Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4694-01A-01R-1277-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Kidney renal clear cell carcinoma_KIRC (The Cancer Genome Atlas)
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304 genes with high or low expression in Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4694-01A-01R-1277-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
ACP2 acid phosphatase 2, lysosomal
ACTN2 actinin, alpha 2
ADAMDEC1 ADAM-like, decysin 1
ADGRG2 adhesion G protein-coupled receptor G2
ADI1 acireductone dioxygenase 1
ADORA3 adenosine A3 receptor
ADPRHL1 ADP-ribosylhydrolase like 1
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
ALK anaplastic lymphoma receptor tyrosine kinase
ALOX15B arachidonate 15-lipoxygenase, type B
ANGPTL5 angiopoietin-like 5
ANKRD2 ankyrin repeat domain 2 (stretch responsive muscle)
ANKRD55 ankyrin repeat domain 55
ANO7 anoctamin 7
AOAH acyloxyacyl hydrolase (neutrophil)
AP2A1 adaptor-related protein complex 2, alpha 1 subunit
APOC1 apolipoprotein C-I
ARPC1B actin related protein 2/3 complex, subunit 1B, 41kDa
ARPC2 actin related protein 2/3 complex, subunit 2, 34kDa
ASB13 ankyrin repeat and SOCS box containing 13
ASB4 ankyrin repeat and SOCS box containing 4
ASCC1 activating signal cointegrator 1 complex subunit 1
ATF5 activating transcription factor 5
ATP6V1B2 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2
ATP9B ATPase, class II, type 9B
AVP arginine vasopressin
AWAT1 acyl-CoA wax alcohol acyltransferase 1
B2M beta-2-microglobulin
BHLHA15 basic helix-loop-helix family, member a15
BST1 bone marrow stromal cell antigen 1
BSX brain-specific homeobox
C17ORF50 chromosome 17 open reading frame 50
C19ORF40 chromosome 19 open reading frame 40
C1QA complement component 1, q subcomponent, A chain
C1QB complement component 1, q subcomponent, B chain
C1QC complement component 1, q subcomponent, C chain
C3AR1 complement component 3a receptor 1
C3ORF30 chromosome 3 open reading frame 30
C4ORF3 chromosome 4 open reading frame 3
CA6 carbonic anhydrase VI
CAPG capping protein (actin filament), gelsolin-like
CARS2 cysteinyl-tRNA synthetase 2, mitochondrial (putative)
CCDC64B coiled-coil domain containing 64B
CCDC91 coiled-coil domain containing 91
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)
CCR1 chemokine (C-C motif) receptor 1
CCZ1 CCZ1 vacuolar protein trafficking and biogenesis associated homolog (S. cerevisiae)
CD14 CD14 molecule
CD226 CD226 molecule
CD244 CD244 molecule, natural killer cell receptor 2B4
CD300A CD300a molecule
CD300LB CD300 molecule-like family member b
CD48 CD48 molecule
CD52 CD52 molecule
CD53 CD53 molecule
CD68 CD68 molecule
CD81 CD81 molecule
CD86 CD86 molecule
CECR1 cat eye syndrome chromosome region, candidate 1
CES2 carboxylesterase 2
CGREF1 cell growth regulator with EF-hand domain 1
CHGA chromogranin A
CHRNA1 cholinergic receptor, nicotinic, alpha 1 (muscle)
CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2
CLRN2 clarin 2
CMKLR1 chemerin chemokine-like receptor 1
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family)
COPS6 COP9 signalosome subunit 6
CORO2A coronin, actin binding protein, 2A
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
CRTAM cytotoxic and regulatory T cell molecule
CRYBB1 crystallin, beta B1
CTSB cathepsin B
CTSS cathepsin S
CTSZ cathepsin Z
CXCL11 chemokine (C-X-C motif) ligand 11
CXCL16 chemokine (C-X-C motif) ligand 16
CXCR6 chemokine (C-X-C motif) receptor 6
DBNL drebrin-like
DCC DCC netrin 1 receptor
DHRS9 dehydrogenase/reductase (SDR family) member 9
DIO3 deiodinase, iodothyronine, type III
DNAJB12 DnaJ (Hsp40) homolog, subfamily B, member 12
DNAJB13 DnaJ (Hsp40) homolog, subfamily B, member 13
DNAJC5B DnaJ (Hsp40) homolog, subfamily C, member 5 beta
DNASE2 deoxyribonuclease II, lysosomal
DNASE2B deoxyribonuclease II beta
DNPEP aspartyl aminopeptidase
DOPEY2 dopey family member 2
DPT dermatopontin
DTHD1 death domain containing 1
EDN3 endothelin 3
EHD2 EH-domain containing 2
EPHA10 EPH receptor A10
ESX1 ESX homeobox 1
EVX1 even-skipped homeobox 1
FAM71C family with sequence similarity 71, member C
FBXO25 F-box protein 25
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide
FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64)
FCGR1B Fc fragment of IgG, high affinity Ib, receptor (CD64)
FCGR3A Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
FCGRT Fc fragment of IgG, receptor, transporter, alpha
FMOD fibromodulin
FOLR2 folate receptor 2 (fetal)
FOXP3 forkhead box P3
FPR3 formyl peptide receptor 3
FTL ferritin, light polypeptide
FUCA1 fucosidase, alpha-L- 1, tissue
GAS2L2 growth arrest-specific 2 like 2
GCHFR GTP cyclohydrolase I feedback regulator
GFAP glial fibrillary acidic protein
GM2A GM2 ganglioside activator
GP5 glycoprotein V (platelet)
GPR35 G protein-coupled receptor 35
GPR45 G protein-coupled receptor 45
GPR62 G protein-coupled receptor 62
GPR89B G protein-coupled receptor 89B
GSDMD gasdermin D
H2BFWT H2B histone family, member W, testis-specific
HAR1A highly accelerated region 1A (non-protein coding)
HCK HCK proto-oncogene, Src family tyrosine kinase
HENMT1 HEN1 methyltransferase homolog 1 (Arabidopsis)
HEXA-AS1 HEXA antisense RNA 1
HGFAC HGF activator
HIST1H2AH histone cluster 1, H2ah
HLA-DMB major histocompatibility complex, class II, DM beta
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HLA-DRA major histocompatibility complex, class II, DR alpha
HNF4A hepatocyte nuclear factor 4, alpha
HPSE heparanase
HS3ST2 heparan sulfate (glucosamine) 3-O-sulfotransferase 2
HTRA4 HtrA serine peptidase 4
IFI30 interferon, gamma-inducible protein 30
IGFBP3 insulin-like growth factor binding protein 3
IGLON5 IgLON family member 5
IL1RN interleukin 1 receptor antagonist
IL26 interleukin 26
IL27RA interleukin 27 receptor, alpha
IL4I1 interleukin 4 induced 1
IMP4 IMP4, U3 small nucleolar ribonucleoprotein
ITGAD integrin, alpha D
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
ITIH5 inter-alpha-trypsin inhibitor heavy chain family, member 5
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3
KCNG1 potassium channel, voltage gated modifier subfamily G, member 1
KCNK18 potassium channel, two pore domain subfamily K, member 18
KIAA1755 KIAA1755
KLHDC7B kelch domain containing 7B
KLRC4 killer cell lectin-like receptor subfamily C, member 4
KLRG1 killer cell lectin-like receptor subfamily G, member 1
KRT36 keratin 36, type I
LACTB lactamase, beta
LAP3 leucine aminopeptidase 3
LAPTM5 lysosomal protein transmembrane 5
LAT linker for activation of T cells
LBX2 ladybird homeobox 2
LCP1 lymphocyte cytosolic protein 1 (L-plastin)
LGALS9 lectin, galactoside-binding, soluble, 9
LILRA2 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2
LILRA4 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 4
LILRB4 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4
LINC00189 long intergenic non-protein coding RNA 189
LIPA lipase A, lysosomal acid, cholesterol esterase
LOC100133985 uncharacterized LOC100133985
LOC340357 uncharacterized LOC340357
LOC653786 otoancorin pseudogene
LPXN leupaxin
LRPAP1 low density lipoprotein receptor-related protein associated protein 1
LSP1 lymphocyte-specific protein 1
LY9 lymphocyte antigen 9
MACROD2 MACRO domain containing 2
MANEAL mannosidase, endo-alpha-like
MAP2K1 mitogen-activated protein kinase kinase 1
ME2 malic enzyme 2, NAD(+)-dependent, mitochondrial
MEDAG mesenteric estrogen-dependent adipogenesis
MFSD1 major facilitator superfamily domain containing 1
MMP12 matrix metallopeptidase 12
MMP19 matrix metallopeptidase 19
MMP8 matrix metallopeptidase 8
MOGAT3 monoacylglycerol O-acyltransferase 3
MRGPRF MAS-related GPR, member F
MS4A4A membrane-spanning 4-domains, subfamily A, member 4A
MS4A6A membrane-spanning 4-domains, subfamily A, member 6A
MS4A6E membrane-spanning 4-domains, subfamily A, member 6E
MSLN mesothelin
MSR1 macrophage scavenger receptor 1
MSRB2 methionine sulfoxide reductase B2
MYOD1 myogenic differentiation 1
NAGA N-acetylgalactosaminidase, alpha-
NAGK N-acetylglucosamine kinase
NBL1 neuroblastoma 1, DAN family BMP antagonist
NCF1B neutrophil cytosolic factor 1B pseudogene
NCF2 neutrophil cytosolic factor 2
NECAP2 NECAP endocytosis associated 2
NEFL neurofilament, light polypeptide
NFAM1 NFAT activating protein with ITAM motif 1
NKG7 natural killer cell granule protein 7
OLFM1 olfactomedin 1
OPN1SW opsin 1 (cone pigments), short-wave-sensitive
OR10H5 olfactory receptor, family 10, subfamily H, member 5
OR51T1 olfactory receptor, family 51, subfamily T, member 1
OR5K1 olfactory receptor, family 5, subfamily K, member 1
OSCAR osteoclast associated, immunoglobulin-like receptor
OTOA otoancorin
OXA1L oxidase (cytochrome c) assembly 1-like
OXCT2 3-oxoacid CoA transferase 2
OXT oxytocin/neurophysin I prepropeptide
PANX3 pannexin 3
PARVB parvin, beta
PCDHGB3 protocadherin gamma subfamily B, 3
PCTP phosphatidylcholine transfer protein
PDE6G phosphodiesterase 6G, cGMP-specific, rod, gamma
PGLYRP4 peptidoglycan recognition protein 4
PGPEP1L pyroglutamyl-peptidase I-like
PILRA paired immunoglobin-like type 2 receptor alpha
PKD2L1 polycystic kidney disease 2-like 1
PKP2 plakophilin 2
PLA2G12B phospholipase A2, group XIIB
PLA2G2D phospholipase A2, group IID
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
PLD3 phospholipase D family, member 3
PLEK pleckstrin
PLTP phospholipid transfer protein
PMS2P1 postmeiotic segregation increased 2 pseudogene 1
POU6F2 POU class 6 homeobox 2
PPIAL4C peptidylprolyl isomerase A (cyclophilin A)-like 4C
PPIAL4G peptidylprolyl isomerase A (cyclophilin A)-like 4G
PPM1M protein phosphatase, Mg2+/Mn2+ dependent, 1M
PPP1R36 protein phosphatase 1, regulatory subunit 36
PPT1 palmitoyl-protein thioesterase 1
PRTFDC1 phosphoribosyl transferase domain containing 1
PSAP prosaposin
PYGL phosphorylase, glycogen, liver
RAB37 RAB37, member RAS oncogene family
RAB42 RAB42, member RAS oncogene family
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
RBFA ribosome binding factor A (putative)
RNF212 ring finger protein 212
RYR1 ryanodine receptor 1 (skeletal)
SARDH sarcosine dehydrogenase
SCN10A sodium channel, voltage gated, type X alpha subunit
SDC3 syndecan 3
SH2D4B SH2 domain containing 4B
SHMT2 serine hydroxymethyltransferase 2 (mitochondrial)
SIGLEC1 sialic acid binding Ig-like lectin 1, sialoadhesin
SIGLEC5 sialic acid binding Ig-like lectin 5
SIGLEC8 sialic acid binding Ig-like lectin 8
SIRPB1 signal-regulatory protein beta 1
SIT1 signaling threshold regulating transmembrane adaptor 1
SLAMF8 SLAM family member 8
SLAMF9 SLAM family member 9
SLC15A3 solute carrier family 15 (oligopeptide transporter), member 3
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3
SLC22A18 solute carrier family 22, member 18
SLC22A18AS solute carrier family 22 (organic cation transporter), member 18 antisense
SLC28A3 solute carrier family 28 (concentrative nucleoside transporter), member 3
SLC29A3 solute carrier family 29 (equilibrative nucleoside transporter), member 3
SLC2A9 solute carrier family 2 (facilitated glucose transporter), member 9
SLC31A2 solute carrier family 31 (copper transporter), member 2
SLC6A11 solute carrier family 6 (neurotransmitter transporter), member 11
SLC6A5 solute carrier family 6 (neurotransmitter transporter), member 5
SLC9A9 solute carrier family 9, subfamily A (NHE9, cation proton antiporter 9), member 9
SMAP2 small ArfGAP2
SMPDL3B sphingomyelin phosphodiesterase, acid-like 3B
SNORA1 small nucleolar RNA, H/ACA box 1
SNORA14B small nucleolar RNA, H/ACA box 14B
SNORA16A small nucleolar RNA, H/ACA box 16A
SNORA27 small nucleolar RNA, H/ACA box 27
SNORA75 small nucleolar RNA, H/ACA box 75
SNX8 sorting nexin 8
SOWAHD sosondowah ankyrin repeat domain family member D
SOX30 SRY (sex determining region Y)-box 30
SP5 Sp5 transcription factor
STAT5A signal transducer and activator of transcription 5A
STK31 serine/threonine kinase 31
STXBP2 syntaxin binding protein 2
SUMO3 small ubiquitin-like modifier 3
TEX11 testis expressed 11
TMEM150B transmembrane protein 150B
TMEM92 transmembrane protein 92
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b
TPI1 triosephosphate isomerase 1
TREM2 triggering receptor expressed on myeloid cells 2
TRIM35 tripartite motif containing 35
TRIM54 tripartite motif containing 54
TYMP thymidine phosphorylase
TYROBP TYRO protein tyrosine kinase binding protein
VMO1 vitelline membrane outer layer 1 homolog (chicken)
VSIG4 V-set and immunoglobulin domain containing 4
WWC2-AS2 WWC2 antisense RNA 2
XKR9 XK, Kell blood group complex subunit-related family, member 9
YBX1 Y box binding protein 1
ZNF521 zinc finger protein 521
ZNF541 zinc finger protein 541

low expression

Symbol Name
BRD2 bromodomain containing 2
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase
KIAA0753 KIAA0753
MAP3K4 mitogen-activated protein kinase kinase kinase 4
NUP43 nucleoporin 43kDa
TBC1D22B TBC1 domain family, member 22B
TRIM39 tripartite motif containing 39
ZNF527 zinc finger protein 527