Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5402-01A-01R-1503-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Kidney renal clear cell carcinoma_KIRC (The Cancer Genome Atlas)
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417 genes with high or low expression in Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5402-01A-01R-1503-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
A2M alpha-2-macroglobulin
AAMP angio-associated, migratory cell protein
ADAM22 ADAM metallopeptidase domain 22
ADGRG2 adhesion G protein-coupled receptor G2
ADI1 acireductone dioxygenase 1
ADRA1A adrenoceptor alpha 1A
ADRA1B adrenoceptor alpha 1B
AFF1 AF4/FMR2 family, member 1
AFF3 AF4/FMR2 family, member 3
AKAP13 A kinase (PRKA) anchor protein 13
ALDH7A1 aldehyde dehydrogenase 7 family, member A1
AMZ2 archaelysin family metallopeptidase 2
ANKHD1 ankyrin repeat and KH domain containing 1
ANKRD16 ankyrin repeat domain 16
ANKRD32 ankyrin repeat domain 32
APOL3 apolipoprotein L, 3
AQP7 aquaporin 7
ARHGAP42 Rho GTPase activating protein 42
ARRDC2 arrestin domain containing 2
ASB13 ankyrin repeat and SOCS box containing 13
ASH2L ash2 (absent, small, or homeotic)-like (Drosophila)
BHLHA15 basic helix-loop-helix family, member a15
BMP4 bone morphogenetic protein 4
BTBD11 BTB (POZ) domain containing 11
C15ORF26 chromosome 15 open reading frame 26
C17ORF107 chromosome 17 open reading frame 107
C17ORF98 chromosome 17 open reading frame 98
C22ORF15 chromosome 22 open reading frame 15
C2ORF27B chromosome 2 open reading frame 27B
C4ORF22 chromosome 4 open reading frame 22
CACHD1 cache domain containing 1
CALCOCO2 calcium binding and coiled-coil domain 2
CBLB Cbl proto-oncogene B, E3 ubiquitin protein ligase
CBLN3 cerebellin 3 precursor
CCDC112 coiled-coil domain containing 112
CCDC146 coiled-coil domain containing 146
CCDC178 coiled-coil domain containing 178
CCDC89 coiled-coil domain containing 89
CCHCR1 coiled-coil alpha-helical rod protein 1
CD109 CD109 molecule
CD300LG CD300 molecule-like family member g
CDC5L cell division cycle 5-like
CDH26 cadherin 26
CEP112 centrosomal protein 112kDa
CEP120 centrosomal protein 120kDa
CHD2 chromodomain helicase DNA binding protein 2
CHMP4A charged multivesicular body protein 4A
CNOT8 CCR4-NOT transcription complex, subunit 8
COG6 component of oligomeric golgi complex 6
COLCA1 colorectal cancer associated 1
COLCA2 colorectal cancer associated 2
COMP cartilage oligomeric matrix protein
COPA coatomer protein complex, subunit alpha
COPB1 coatomer protein complex, subunit beta 1
COPB2 coatomer protein complex, subunit beta 2 (beta prime)
CPM carboxypeptidase M
CRADD CASP2 and RIPK1 domain containing adaptor with death domain
CSHL1 chorionic somatomammotropin hormone-like 1
CUL7 cullin 7
CYP7B1 cytochrome P450, family 7, subfamily B, polypeptide 1
DCAF12L1 DDB1 and CUL4 associated factor 12-like 1
DCTN6 dynactin 6
DDX42 DEAD (Asp-Glu-Ala-Asp) box helicase 42
DDX46 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46
DEPTOR DEP domain containing MTOR-interacting protein
DIEXF digestive organ expansion factor homolog (zebrafish)
DIS3L DIS3 like exosome 3'-5' exoribonuclease
DIXDC1 DIX domain containing 1
DKFZP434K028 uncharacterized LOC26070
DNAH11 dynein, axonemal, heavy chain 11
DNAJB13 DnaJ (Hsp40) homolog, subfamily B, member 13
DNM1P46 dynamin 1 pseudogene 46
DOCK9 dedicator of cytokinesis 9
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1
DZIP3 DAZ interacting zinc finger protein 3
EBAG9 estrogen receptor binding site associated, antigen, 9
EFHC2 EF-hand domain (C-terminal) containing 2
EIF2AK4 eukaryotic translation initiation factor 2 alpha kinase 4
ELP2 elongator acetyltransferase complex subunit 2
EPHA6 EPH receptor A6
EPRS glutamyl-prolyl-tRNA synthetase
ERICH5 glutamate-rich 5
ERN1 endoplasmic reticulum to nucleus signaling 1
ETNK2 ethanolamine kinase 2
EYS eyes shut homolog (Drosophila)
F2RL1 coagulation factor II (thrombin) receptor-like 1
FAM199X family with sequence similarity 199, X-linked
FAM214A family with sequence similarity 214, member A
FAM50B family with sequence similarity 50, member B
FAM76A family with sequence similarity 76, member A
FAM8A1 family with sequence similarity 8, member A1
FBXO21 F-box protein 21
FBXO38 F-box protein 38
FBXO48 F-box protein 48
FCN3 ficolin (collagen/fibrinogen domain containing) 3
FGD4 FYVE, RhoGEF and PH domain containing 4
FHL5 four and a half LIM domains 5
FKBP5 FK506 binding protein 5
FLNB filamin B, beta
FOLH1 folate hydrolase (prostate-specific membrane antigen) 1
FOLH1B folate hydrolase 1B
FOXO3 forkhead box O3
FOXO3B forkhead box O3B pseudogene
FOXP2 forkhead box P2
FRG1B FSHD region gene 1 family, member B
FRRS1 ferric-chelate reductase 1
FUNDC2P2 FUN14 domain containing 2 pseudogene 2
GALNT15 polypeptide N-acetylgalactosaminyltransferase 15
GCLM glutamate-cysteine ligase, modifier subunit
GEMIN5 gem (nuclear organelle) associated protein 5
GFOD1 glucose-fructose oxidoreductase domain containing 1
GHR growth hormone receptor
GLIPR1L2 GLI pathogenesis-related 1 like 2
GLUL glutamate-ammonia ligase
GOLGB1 golgin B1
GPR88 G protein-coupled receptor 88
GPRASP2 G protein-coupled receptor associated sorting protein 2
GPX3 glutathione peroxidase 3
GRAMD3 GRAM domain containing 3
GRB10 growth factor receptor-bound protein 10
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene)
H6PD hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
HACD4 3-hydroxyacyl-CoA dehydratase 4
HBP1 HMG-box transcription factor 1
HEATR5B HEAT repeat containing 5B
HELB helicase (DNA) B
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3
HFE hemochromatosis
HIF3A hypoxia inducible factor 3, alpha subunit
HIRIP3 HIRA interacting protein 3
HIST1H2BN histone cluster 1, H2bn
HIST1H3E histone cluster 1, H3e
HMBOX1 homeobox containing 1
HMGXB4 HMG box domain containing 4
HN1L hematological and neurological expressed 1-like
HNRNPUL2 heterogeneous nuclear ribonucleoprotein U-like 2
HOXC12 homeobox C12
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
HR hair growth associated
HRASLS HRAS-like suppressor
HSD3B2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2
HSPA1L heat shock 70kDa protein 1-like
HSPA9 heat shock 70kDa protein 9 (mortalin)
HTR6 5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial
IDO1 indoleamine 2,3-dioxygenase 1
IGF2BP1 insulin-like growth factor 2 mRNA binding protein 1
IK IK cytokine, down-regulator of HLA II
IL1RL2 interleukin 1 receptor-like 2
IL6R interleukin 6 receptor
ING2 inhibitor of growth family, member 2
IPO5 importin 5
IRGM immunity-related GTPase family, M
JAKMIP2 janus kinase and microtubule interacting protein 2
JPH2 junctophilin 2
KCND2 potassium channel, voltage gated Shal related subfamily D, member 2
KCNJ3 potassium channel, inwardly rectifying subfamily J, member 3
KCTD18 potassium channel tetramerization domain containing 18
KCTD3 potassium channel tetramerization domain containing 3
KGFLP1 fibroblast growth factor 7 pseudogene
KIAA1429 KIAA1429
KIAA1549 KIAA1549
KLF13 Kruppel-like factor 13
KLF15 Kruppel-like factor 15
KLF7 Kruppel-like factor 7 (ubiquitous)
KLHL4 kelch-like family member 4
KLRC1 killer cell lectin-like receptor subfamily C, member 1
KRTAP24-1 keratin associated protein 24-1
KSR2 kinase suppressor of ras 2
LARS leucyl-tRNA synthetase
LEO1 Leo1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)
LGALS4 lectin, galactoside-binding, soluble, 4
LMAN1 lectin, mannose-binding, 1
LOC100134368 uncharacterized LOC100134368
LOC145783 uncharacterized LOC145783
LOC285593 uncharacterized LOC285593
LOC285768 uncharacterized LOC285768
LOC285847 uncharacterized LOC285847
LPIN2 lipin 2
LURAP1L leucine rich adaptor protein 1-like
MAOA monoamine oxidase A
MAP7D3 MAP7 domain containing 3
MASTL microtubule associated serine/threonine kinase-like
MCC mutated in colorectal cancers
MED30 mediator complex subunit 30
MGAM maltase-glucoamylase
MGAT5 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase
MIA2 melanoma inhibitory activity 2
MIOS missing oocyte, meiosis regulator, homolog (Drosophila)
MLH3 mutL homolog 3
MLIP muscular LMNA-interacting protein
MMRN1 multimerin 1
MON2 MON2 homolog (S. cerevisiae)
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
MRPS23 mitochondrial ribosomal protein S23
MTR 5-methyltetrahydrofolate-homocysteine methyltransferase
MUM1L1 melanoma associated antigen (mutated) 1-like 1
MXD4 MAX dimerization protein 4
MYCBP2 MYC binding protein 2, E3 ubiquitin protein ligase
MYO9A myosin IXA
NBN nibrin
NBPF14 neuroblastoma breakpoint family, member 14
NCOA3 nuclear receptor coactivator 3
NCR1 natural cytotoxicity triggering receptor 1
NEK5 NIMA-related kinase 5
NETO1 neuropilin (NRP) and tolloid (TLL)-like 1
NFE2L1 nuclear factor, erythroid 2-like 1
NFXL1 nuclear transcription factor, X-box binding-like 1
NRG1 neuregulin 1
NUCB2 nucleobindin 2
NUDT16 nudix (nucleoside diphosphate linked moiety X)-type motif 16
NUDT17 nudix (nucleoside diphosphate linked moiety X)-type motif 17
NYNRIN NYN domain and retroviral integrase containing
OPCML opioid binding protein/cell adhesion molecule-like
OR13J1 olfactory receptor, family 13, subfamily J, member 1
OR5B3 olfactory receptor, family 5, subfamily B, member 3
OR5K4 olfactory receptor, family 5, subfamily K, member 4
OR6B1 olfactory receptor, family 6, subfamily B, member 1
OSBPL11 oxysterol binding protein-like 11
OSBPL1A oxysterol binding protein-like 1A
OSGIN2 oxidative stress induced growth inhibitor family member 2
OTUB2 OTU deubiquitinase, ubiquitin aldehyde binding 2
OTUD7A OTU deubiquitinase 7A
OTUD7B OTU deubiquitinase 7B
P2RX3 purinergic receptor P2X, ligand gated ion channel, 3
P3H2 prolyl 3-hydroxylase 2
PAK3 p21 protein (Cdc42/Rac)-activated kinase 3
PCDHA10 protocadherin alpha 10
PCDHA11 protocadherin alpha 11
PCDHB12 protocadherin beta 12
PCDHGB1 protocadherin gamma subfamily B, 1
PCDHGB7 protocadherin gamma subfamily B, 7
PCM1 pericentriolar material 1
PCTP phosphatidylcholine transfer protein
PDCD7 programmed cell death 7
PDE7A phosphodiesterase 7A
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PGA4 pepsinogen 4, group I (pepsinogen A)
PHAX phosphorylated adaptor for RNA export
PHF3 PHD finger protein 3
PI16 peptidase inhibitor 16
PIAS1 protein inhibitor of activated STAT, 1
PITRM1 pitrilysin metallopeptidase 1
PIWIL2 piwi-like RNA-mediated gene silencing 2
PJA2 praja ring finger 2, E3 ubiquitin protein ligase
PKP2 plakophilin 2
PNMA2 paraneoplastic Ma antigen 2
POLR3C polymerase (RNA) III (DNA directed) polypeptide C (62kD)
POLR3D polymerase (RNA) III (DNA directed) polypeptide D, 44kDa
PPAPDC1B phosphatidic acid phosphatase type 2 domain containing 1B
PPP1R8 protein phosphatase 1, regulatory subunit 8
PPP2CB protein phosphatase 2, catalytic subunit, beta isozyme
PRMT5 protein arginine methyltransferase 5
PROS1 protein S (alpha)
PRPF8 pre-mRNA processing factor 8
PRR26 proline rich 26
PRRC1 proline-rich coiled-coil 1
PRSS12 protease, serine, 12 (neurotrypsin, motopsin)
PRSS16 protease, serine, 16 (thymus)
PSD4 pleckstrin and Sec7 domain containing 4
PTGER3 prostaglandin E receptor 3 (subtype EP3)
PTPN9 protein tyrosine phosphatase, non-receptor type 9
PTPRB protein tyrosine phosphatase, receptor type, B
PWP1 PWP1 homolog (S. cerevisiae)
RAPGEF6 Rap guanine nucleotide exchange factor (GEF) 6
RARB retinoic acid receptor, beta
RASL11A RAS-like, family 11, member A
RAVER2 ribonucleoprotein, PTB-binding 2
RBM24 RNA binding motif protein 24
RERE arginine-glutamic acid dipeptide (RE) repeats
RERG RAS-like, estrogen-regulated, growth inhibitor
RFX3 regulatory factor X, 3 (influences HLA class II expression)
RHOB ras homolog family member B
RNASE11 ribonuclease, RNase A family, 11 (non-active)
RNASE4 ribonuclease, RNase A family, 4
RNF115 ring finger protein 115
RNF125 ring finger protein 125, E3 ubiquitin protein ligase
RNF151 ring finger protein 151
RNF170 ring finger protein 170
RNF214 ring finger protein 214
RNF5P1 ring finger protein 5, E3 ubiquitin protein ligase pseudogene 1
RORA RAR-related orphan receptor A
RPS4Y1 ribosomal protein S4, Y-linked 1
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5
RSG1 REM2 and RAB-like small GTPase 1
RSL1D1 ribosomal L1 domain containing 1
RTTN rotatin
RUFY1 RUN and FYVE domain containing 1
SARAF store-operated calcium entry-associated regulatory factor
SCN8A sodium channel, voltage gated, type VIII alpha subunit
SCN9A sodium channel, voltage gated, type IX alpha subunit
SDPR serum deprivation response
SEC31A SEC31 homolog A (S. cerevisiae)
SENP2 SUMO1/sentrin/SMT3 specific peptidase 2
SH2D1B SH2 domain containing 1B
SLC10A6 solute carrier family 10 (sodium/bile acid cotransporter), member 6
SLC26A9 solute carrier family 26 (anion exchanger), member 9
SLC35E3 solute carrier family 35, member E3
SLC38A2 solute carrier family 38, member 2
SLC39A14 solute carrier family 39 (zinc transporter), member 14
SMCR8 Smith-Magenis syndrome chromosome region, candidate 8
SMG8 SMG8 nonsense mediated mRNA decay factor
SMYD4 SET and MYND domain containing 4
SNORA27 small nucleolar RNA, H/ACA box 27
SNORA75 small nucleolar RNA, H/ACA box 75
SNORD115-26 small nucleolar RNA, C/D box 115-26
SNORD116-4 small nucleolar RNA, C/D box 116-4
SNRNP200 small nuclear ribonucleoprotein 200kDa (U5)
SORBS2 sorbin and SH3 domain containing 2
SP6 Sp6 transcription factor
SPATA17 spermatogenesis associated 17
SPECC1L sperm antigen with calponin homology and coiled-coil domains 1-like
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor)
SPRY2 sprouty homolog 2 (Drosophila)
SRD5A3 steroid 5 alpha-reductase 3
SRP68 signal recognition particle 68kDa
SRRM4 serine/arginine repetitive matrix 4
SSR3 signal sequence receptor, gamma (translocon-associated protein gamma)
ST13 suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein)
ST18 suppression of tumorigenicity 18, zinc finger
STAG1 stromal antigen 1
STAMBP STAM binding protein
STARD13 StAR-related lipid transfer (START) domain containing 13
STARD8 StAR-related lipid transfer (START) domain containing 8
STC1 stanniocalcin 1
STK39 serine threonine kinase 39
STON1-GTF2A1L STON1-GTF2A1L readthrough
STX12 syntaxin 12
SYBU syntabulin (syntaxin-interacting)
TACC1 transforming, acidic coiled-coil containing protein 1
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
TAF8 TAF8 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 43kDa
TAPBPL TAP binding protein-like
TARSL2 threonyl-tRNA synthetase-like 2
TBC1D10A TBC1 domain family, member 10A
TBC1D8 TBC1 domain family, member 8 (with GRAM domain)
TBC1D8B TBC1 domain family, member 8B (with GRAM domain)
TCP11L1 t-complex 11, testis-specific-like 1
TEDDM1 transmembrane epididymal protein 1
TEX15 testis expressed 15
THRAP3 thyroid hormone receptor associated protein 3
TIMP4 TIMP metallopeptidase inhibitor 4
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TIRAP toll-interleukin 1 receptor (TIR) domain containing adaptor protein
TLN2 talin 2
TMCO6 transmembrane and coiled-coil domains 6
TMEM100 transmembrane protein 100
TMEM106A transmembrane protein 106A
TMEM159 transmembrane protein 159
TMEM39A transmembrane protein 39A
TMEM91 transmembrane protein 91
TNFRSF10A tumor necrosis factor receptor superfamily, member 10a
TNS1 tensin 1
TOR1AIP2 torsin A interacting protein 2
TOX4 TOX high mobility group box family member 4
TP53TG3B TP53 target 3B
TPO thyroid peroxidase
TPR translocated promoter region, nuclear basket protein
TRIM4 tripartite motif containing 4
TRIM5 tripartite motif containing 5
TRIM56 tripartite motif containing 56
TRIM6-TRIM34 TRIM6-TRIM34 readthrough
TRIM61 tripartite motif containing 61
TSPYL2 TSPY-like 2
TSSK1B testis-specific serine kinase 1B
TTC17 tetratricopeptide repeat domain 17
TTC37 tetratricopeptide repeat domain 37
TUBA3C tubulin, alpha 3c
TUBA3D tubulin, alpha 3d
TUBA3E tubulin, alpha 3e
TXLNGY taxilin gamma pseudogene, Y-linked
USO1 USO1 vesicle transport factor
USP13 ubiquitin specific peptidase 13 (isopeptidase T-3)
USP48 ubiquitin specific peptidase 48
UTY ubiquitously transcribed tetratricopeptide repeat containing, Y-linked
WASF2 WAS protein family, member 2
WBP4 WW domain binding protein 4
WDR66 WD repeat domain 66
WDR81 WD repeat domain 81
YIPF5 Yip1 domain family, member 5
YME1L1 YME1-like 1 ATPase
ZBED3 zinc finger, BED-type containing 3
ZBTB16 zinc finger and BTB domain containing 16
ZC2HC1C zinc finger, C2HC-type containing 1C
ZC3H13 zinc finger CCCH-type containing 13
ZC3H7A zinc finger CCCH-type containing 7A
ZKSCAN3 zinc finger with KRAB and SCAN domains 3
ZNF184 zinc finger protein 184
ZNF281 zinc finger protein 281
ZNF366 zinc finger protein 366
ZNF37A zinc finger protein 37A
ZNF391 zinc finger protein 391
ZNF397 zinc finger protein 397
ZNF430 zinc finger protein 430
ZNF521 zinc finger protein 521
ZNF526 zinc finger protein 526
ZNF543 zinc finger protein 543
ZNF546 zinc finger protein 546
ZNF550 zinc finger protein 550
ZNF616 zinc finger protein 616
ZNF646 zinc finger protein 646
ZNF704 zinc finger protein 704
ZNF766 zinc finger protein 766
ZNF776 zinc finger protein 776
ZNF804B zinc finger protein 804B
ZNF826P zinc finger protein 826, pseudogene
ZPR1 ZPR1 zinc finger
ZSCAN20 zinc finger and SCAN domain containing 20
ZXDB zinc finger, X-linked, duplicated B

low expression

Symbol Name
ADO 2-aminoethanethiol (cysteamine) dioxygenase
DDX19B DEAD (Asp-Glu-Ala-Asp) box polypeptide 19B
TERF2 telomeric repeat binding factor 2
USP10 ubiquitin specific peptidase 10
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1