Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4962-01A-01R-1334-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Kidney renal clear cell carcinoma_KIRC (The Cancer Genome Atlas)
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425 genes with high or low expression in Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4962-01A-01R-1334-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
ABLIM2 actin binding LIM protein family, member 2
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2
ACO2 aconitase 2, mitochondrial
ACOT7 acyl-CoA thioesterase 7
ACP2 acid phosphatase 2, lysosomal
ACSF3 acyl-CoA synthetase family member 3
ACSM6 acyl-CoA synthetase medium-chain family member 6
ACSS2 acyl-CoA synthetase short-chain family member 2
ACTA2 actin, alpha 2, smooth muscle, aorta
ADAP1 ArfGAP with dual PH domains 1
ADCK2 aarF domain containing kinase 2
ADGRL3 adhesion G protein-coupled receptor L3
ADORA3 adenosine A3 receptor
AGXT2 alanine--glyoxylate aminotransferase 2
AHCY adenosylhomocysteinase
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase)
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase)
ALDH3B1 aldehyde dehydrogenase 3 family, member B1
ALDH4A1 aldehyde dehydrogenase 4 family, member A1
ALOX5 arachidonate 5-lipoxygenase
ANTXR1 anthrax toxin receptor 1
AOC3 amine oxidase, copper containing 3
AOX2P aldehyde oxidase 2 pseudogene
AP1M1 adaptor-related protein complex 1, mu 1 subunit
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
AP2A1 adaptor-related protein complex 2, alpha 1 subunit
AQP1 aquaporin 1 (Colton blood group)
ARHGAP10 Rho GTPase activating protein 10
ARMC4 armadillo repeat containing 4
ART4 ADP-ribosyltransferase 4 (Dombrock blood group)
ASB13 ankyrin repeat and SOCS box containing 13
ASPHD1 aspartate beta-hydroxylase domain containing 1
ATG13 autophagy related 13
ATG16L1 autophagy related 16-like 1 (S. cerevisiae)
ATP5G3 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9)
ATP6V1B2 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2
AVP arginine vasopressin
B3GAT1 beta-1,3-glucuronyltransferase 1
B4GALT2 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
BAK1 BCL2-antagonist/killer 1
BCL2L1 BCL2-like 1
BCL7B B-cell CLL/lymphoma 7B
BHLHA15 basic helix-loop-helix family, member a15
BST1 bone marrow stromal cell antigen 1
BTBD17 BTB (POZ) domain containing 17
C10ORF76 chromosome 10 open reading frame 76
C11ORF49 chromosome 11 open reading frame 49
C17ORF98 chromosome 17 open reading frame 98
C19ORF12 chromosome 19 open reading frame 12
C1ORF198 chromosome 1 open reading frame 198
C1QTNF7 C1q and tumor necrosis factor related protein 7
C20ORF24 chromosome 20 open reading frame 24
C9ORF116 chromosome 9 open reading frame 116
C9ORF91 chromosome 9 open reading frame 91
CALD1 caldesmon 1
CAPN1 calpain 1, (mu/I) large subunit
CAPN6 calpain 6
CCDC103 coiled-coil domain containing 103
CCDC106 coiled-coil domain containing 106
CCDC146 coiled-coil domain containing 146
CCDC3 coiled-coil domain containing 3
CCDC51 coiled-coil domain containing 51
CCDC80 coiled-coil domain containing 80
CCL15 chemokine (C-C motif) ligand 15
CCL25 chemokine (C-C motif) ligand 25
CCR9 chemokine (C-C motif) receptor 9
CDHR1 cadherin-related family member 1
CDIP1 cell death-inducing p53 target 1
CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35)
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CHMP1A charged multivesicular body protein 1A
CHRM4 cholinergic receptor, muscarinic 4
CLEC18C C-type lectin domain family 18, member C
CNN1 calponin 1, basic, smooth muscle
CNPPD1 cyclin Pas1/PHO80 domain containing 1
COL14A1 collagen, type XIV, alpha 1
CPED1 cadherin-like and PC-esterase domain containing 1
CRAT carnitine O-acetyltransferase
CREB3 cAMP responsive element binding protein 3
CRYBB1 crystallin, beta B1
CRYBB3 crystallin, beta B3
CSN2 casein beta
CSRP1 cysteine and glycine-rich protein 1
CTNND2 catenin (cadherin-associated protein), delta 2
CTSE cathepsin E
CYB561 cytochrome b561
CYB561A3 cytochrome b561 family, member A3
CYBRD1 cytochrome b reductase 1
CYP11B2 cytochrome P450, family 11, subfamily B, polypeptide 2
DBNL drebrin-like
DEFB128 defensin, beta 128
DENND1A DENN/MADD domain containing 1A
DGCR2 DiGeorge syndrome critical region gene 2
DGCR5 DiGeorge syndrome critical region gene 5 (non-protein coding)
DHRS12 dehydrogenase/reductase (SDR family) member 12
DHRS3 dehydrogenase/reductase (SDR family) member 3
DNAJC5 DnaJ (Hsp40) homolog, subfamily C, member 5
DNASE2 deoxyribonuclease II, lysosomal
DNER delta/notch-like EGF repeat containing
DNPEP aspartyl aminopeptidase
DUSP10 dual specificity phosphatase 10
E2F1 E2F transcription factor 1
EFHD2 EF-hand domain family, member D2
ELN elastin
ENPP7 ectonucleotide pyrophosphatase/phosphodiesterase 7
EPB41 erythrocyte membrane protein band 4.1
EPHA10 EPH receptor A10
ESRRA estrogen-related receptor alpha
EVA1A eva-1 homolog A (C. elegans)
FABP6 fatty acid binding protein 6, ileal
FADS6 fatty acid desaturase 6
FAM118B family with sequence similarity 118, member B
FAM120A family with sequence similarity 120A
FAM120AOS family with sequence similarity 120A opposite strand
FAM129A family with sequence similarity 129, member A
FAM134A family with sequence similarity 134, member A
FAM134B family with sequence similarity 134, member B
FAM53B family with sequence similarity 53, member B
FBXO44 F-box protein 44
FGGY FGGY carbohydrate kinase domain containing
FMO3 flavin containing monooxygenase 3
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase)
GALE UDP-galactose-4-epimerase
GALK1 galactokinase 1
GCHFR GTP cyclohydrolase I feedback regulator
GHRHR growth hormone releasing hormone receptor
GLMP glycosylated lysosomal membrane protein
GML glycosylphosphatidylinositol anchored molecule like
GMPPB GDP-mannose pyrophosphorylase B
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide
GPHB5 glycoprotein hormone beta 5
GPRIN2 G protein regulated inducer of neurite outgrowth 2
GRTP1 growth hormone regulated TBC protein 1
GSDMD gasdermin D
GSTK1 glutathione S-transferase kappa 1
GSTM2P1 glutathione S-transferase mu 2 (muscle) pseudogene 1
GSTM4 glutathione S-transferase mu 4
GSTT1 glutathione S-transferase theta 1
HIST1H2AB histone cluster 1, H2ab
HIST1H4F histone cluster 1, H4f
HLA-DPB1 major histocompatibility complex, class II, DP beta 1
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HLA-DRB5 major histocompatibility complex, class II, DR beta 5
HMGCL 3-hydroxymethyl-3-methylglutaryl-CoA lyase
HMOX1 heme oxygenase 1
HOGA1 4-hydroxy-2-oxoglutarate aldolase 1
HRH2 histamine receptor H2
HS1BP3 HCLS1 binding protein 3
HSD3B7 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
ICMT isoprenylcysteine carboxyl methyltransferase
IFFO2 intermediate filament family orphan 2
IFNA4 interferon, alpha 4
IL17A interleukin 17A
IL26 interleukin 26
INMT indolethylamine N-methyltransferase
IRAK1 interleukin-1 receptor-associated kinase 1
ISOC2 isochorismatase domain containing 2
ITGA11 integrin, alpha 11
ITGA8 integrin, alpha 8
ITGBL1 integrin, beta-like 1 (with EGF-like repeat domains)
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3
KCNJ4 potassium channel, inwardly rectifying subfamily J, member 4
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KCNMB1 potassium channel subfamily M regulatory beta subunit 1
KCNMB4 potassium channel subfamily M regulatory beta subunit 4
KCNS2 potassium voltage-gated channel, modifier subfamily S, member 2
KIAA1522 KIAA1522
KIF1C kinesin family member 1C
KLHL40 kelch-like family member 40
KRT77 keratin 77, type II
KRTAP10-3 keratin associated protein 10-3
KRTAP12-1 keratin associated protein 12-1
KRTAP2-2 keratin associated protein 2-2
KRTAP4-2 keratin associated protein 4-2
KRTAP5-6 keratin associated protein 5-6
KRTAP7-1 keratin associated protein 7-1 (gene/pseudogene)
KRTAP9-9 keratin associated protein 9-9
KSR1 kinase suppressor of ras 1
LCE3A late cornified envelope 3A
LGALS9B lectin, galactoside-binding, soluble, 9B
LILRA2 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2
LIMK1 LIM domain kinase 1
LIN54 lin-54 DREAM MuvB core complex component
LINC00523 long intergenic non-protein coding RNA 523
LMOD1 leiomodin 1 (smooth muscle)
LOC284661 uncharacterized LOC284661
LOC441454 prothymosin, alpha pseudogene
LOC728554 THO complex 3 pseudogene
LPCAT3 lysophosphatidylcholine acyltransferase 3
LPIN2 lipin 2
LRIT1 leucine-rich repeat, immunoglobulin-like and transmembrane domains 1
LRPAP1 low density lipoprotein receptor-related protein associated protein 1
LRRC20 leucine rich repeat containing 20
LRRC7 leucine rich repeat containing 7
LTBP1 latent transforming growth factor beta binding protein 1
LTBP2 latent transforming growth factor beta binding protein 2
LUZP6 leucine zipper protein 6
LY86 lymphocyte antigen 86
MAGEB4 melanoma antigen family B4
MDH1 malate dehydrogenase 1, NAD (soluble)
MDH2 malate dehydrogenase 2, NAD (mitochondrial)
MGAT1 mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
MGP matrix Gla protein
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2
MINOS1 mitochondrial inner membrane organizing system 1
MMP24 matrix metallopeptidase 24 (membrane-inserted)
MOGAT3 monoacylglycerol O-acyltransferase 3
MRPL37 mitochondrial ribosomal protein L37
MSRB3 methionine sulfoxide reductase B3
MVK mevalonate kinase
MYH10 myosin, heavy chain 10, non-muscle
MYH11 myosin, heavy chain 11, smooth muscle
MYL9 myosin, light chain 9, regulatory
MYLK myosin light chain kinase
MYO1D myosin ID
NAGA N-acetylgalactosaminidase, alpha-
NALCN sodium leak channel, non selective
NARFL nuclear prelamin A recognition factor-like
NBL1 neuroblastoma 1, DAN family BMP antagonist
NCEH1 neutral cholesterol ester hydrolase 1
NCS1 neuronal calcium sensor 1
NDRG3 NDRG family member 3
NDUFB3 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa
NECAB3 N-terminal EF-hand calcium binding protein 3
NEFL neurofilament, light polypeptide
NINJ1 ninjurin 1
NIPSNAP1 nipsnap homolog 1 (C. elegans)
NMT1 N-myristoyltransferase 1
NOV nephroblastoma overexpressed
NPPC natriuretic peptide C
NSG1 neuron specific gene family member 1
NT5DC3 5'-nucleotidase domain containing 3
NUCB1 nucleobindin 1
NUDCD3 NudC domain containing 3
NUDT18 nudix (nucleoside diphosphate linked moiety X)-type motif 18
OGDH oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
OGN osteoglycin
OLFM1 olfactomedin 1
OPN1MW opsin 1 (cone pigments), medium-wave-sensitive
OPRL1 opiate receptor-like 1
OR10AG1 olfactory receptor, family 10, subfamily AG, member 1
OR13F1 olfactory receptor, family 13, subfamily F, member 1
OR1M1 olfactory receptor, family 1, subfamily M, member 1
OR2M4 olfactory receptor, family 2, subfamily M, member 4
OR4A16 olfactory receptor, family 4, subfamily A, member 16
OR4C13 olfactory receptor, family 4, subfamily C, member 13
OR4D1 olfactory receptor, family 4, subfamily D, member 1
OR4K14 olfactory receptor, family 4, subfamily K, member 14
OR51D1 olfactory receptor, family 51, subfamily D, member 1
OR52A5 olfactory receptor, family 52, subfamily A, member 5
OR52E2 olfactory receptor, family 52, subfamily E, member 2
OR52E8 olfactory receptor, family 52, subfamily E, member 8
OR52I2 olfactory receptor, family 52, subfamily I, member 2
OR6B1 olfactory receptor, family 6, subfamily B, member 1
OR6C3 olfactory receptor, family 6, subfamily C, member 3
OR7A10 olfactory receptor, family 7, subfamily A, member 10
OR8D2 olfactory receptor, family 8, subfamily D, member 2 (gene/pseudogene)
OTOA otoancorin
PAAF1 proteasomal ATPase-associated factor 1
PALLD palladin, cytoskeletal associated protein
PARVB parvin, beta
PCDH7 protocadherin 7
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PDLIM3 PDZ and LIM domain 3
PDXP pyridoxal (pyridoxine, vitamin B6) phosphatase
PDYN prodynorphin
PEG3-AS1 PEG3 antisense RNA 1
PER4 period circadian clock 3 pseudogene
PEX10 peroxisomal biogenesis factor 10
PGAM1 phosphoglycerate mutase 1 (brain)
PGAM4 phosphoglycerate mutase family member 4
PID1 phosphotyrosine interaction domain containing 1
PITX1 paired-like homeodomain 1
PLA2G12B phospholipase A2, group XIIB
PMCH pro-melanin-concentrating hormone
PMM2 phosphomannomutase 2
PMS2P4 postmeiotic segregation increased 2 pseudogene 4
PODN podocan
POLR2E polymerase (RNA) II (DNA directed) polypeptide E, 25kDa
POTEB POTE ankyrin domain family, member B
PPP1R12B protein phosphatase 1, regulatory subunit 12B
PRADC1 protease-associated domain containing 1
PRDM6 PR domain containing 6
PRELP proline/arginine-rich end leucine-rich repeat protein
PRKAR1B protein kinase, cAMP-dependent, regulatory, type I, beta
PRODH proline dehydrogenase (oxidase) 1
PRR19 proline rich 19
PRR34 proline rich 34
PSAP prosaposin
PTGES prostaglandin E synthase
PTGIS prostaglandin I2 (prostacyclin) synthase
RAB23 RAB23, member RAS oncogene family
RAB3D RAB3D, member RAS oncogene family
RASGEF1A RasGEF domain family, member 1A
RCVRN recoverin
RGS20 regulator of G-protein signaling 20
RGS21 regulator of G-protein signaling 21
RHBDL1 rhomboid, veinlet-like 1 (Drosophila)
RHOC ras homolog family member C
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4
RTCB RNA 2',3'-cyclic phosphate and 5'-OH ligase
RTN1 reticulon 1
RUNX3 runt-related transcription factor 3
SCAMP5 secretory carrier membrane protein 5
SFXN4 sideroflexin 4
SGCD sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)
SH2D5 SH2 domain containing 5
SH3GL1 SH3-domain GRB2-like 1
SH3GL2 SH3-domain GRB2-like 2
SHPK sedoheptulokinase
SIGLEC8 sialic acid binding Ig-like lectin 8
SLC13A1 solute carrier family 13 (sodium/sulfate symporter), member 1
SLC15A3 solute carrier family 15 (oligopeptide transporter), member 3
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3
SLC22A18 solute carrier family 22, member 18
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
SLC25A11 solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11
SLC25A34 solute carrier family 25, member 34
SLC25A42 solute carrier family 25, member 42
SLC2A9 solute carrier family 2 (facilitated glucose transporter), member 9
SLC31A2 solute carrier family 31 (copper transporter), member 2
SLC35A4 solute carrier family 35, member A4
SLC35D2 solute carrier family 35 (UDP-GlcNAc/UDP-glucose transporter), member D2
SLC36A1 solute carrier family 36 (proton/amino acid symporter), member 1
SLC37A2 solute carrier family 37 (glucose-6-phosphate transporter), member 2
SLC39A1 solute carrier family 39 (zinc transporter), member 1
SLC45A3 solute carrier family 45, member 3
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SLC6A20 solute carrier family 6 (proline IMINO transporter), member 20
SLC9A9 solute carrier family 9, subfamily A (NHE9, cation proton antiporter 9), member 9
SMG5 SMG5 nonsense mediated mRNA decay factor
SMOC2 SPARC related modular calcium binding 2
SNORA32 small nucleolar RNA, H/ACA box 32
SNORA4 small nucleolar RNA, H/ACA box 4
SNX8 sorting nexin 8
SPINT1 serine peptidase inhibitor, Kunitz type 1
SPINT2 serine peptidase inhibitor, Kunitz type, 2
SPR sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase)
SRD5A1 steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1)
ST6GALNAC4 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4
STAT5A signal transducer and activator of transcription 5A
STK16 serine/threonine kinase 16
STON1 stonin 1
SUSD5 sushi domain containing 5
SYNPO2 synaptopodin 2
SZRD1 SUZ RNA binding domain containing 1
TAGLN transgelin
TAS2R39 taste receptor, type 2, member 39
TAS2R41 taste receptor, type 2, member 41
TCEB3B transcription elongation factor B polypeptide 3B (elongin A2)
TEX2 testis expressed 2
TEX26 testis expressed 26
THAP9 THAP domain containing 9
THBS2 thrombospondin 2
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast)
TIMP2 TIMP metallopeptidase inhibitor 2
TM6SF2 transmembrane 6 superfamily member 2
TMBIM1 transmembrane BAX inhibitor motif containing 1
TMEM120A transmembrane protein 120A
TMEM132E transmembrane protein 132E
TMEM139 transmembrane protein 139
TMEM222 transmembrane protein 222
TMEM82 transmembrane protein 82
TMEM98 transmembrane protein 98
TNS3 tensin 3
TOLLIP toll interacting protein
TOMM40L translocase of outer mitochondrial membrane 40 homolog (yeast)-like
TPRG1L tumor protein p63 regulated 1-like
TRAPPC3 trafficking protein particle complex 3
TRIM43 tripartite motif containing 43
TRIM77 tripartite motif containing 77
TRPT1 tRNA phosphotransferase 1
TSPAN17 tetraspanin 17
TSSC1 tumor suppressing subtransferable candidate 1
TTC29 tetratricopeptide repeat domain 29
TWF2 twinfilin actin binding protein 2
TXNDC17 thioredoxin domain containing 17
UBE2MP1 ubiquitin-conjugating enzyme E2M pseudogene 1
UBR4 ubiquitin protein ligase E3 component n-recognin 4
UCMA upper zone of growth plate and cartilage matrix associated
UGP2 UDP-glucose pyrophosphorylase 2
UGT3A1 UDP glycosyltransferase 3 family, polypeptide A1
USP35 ubiquitin specific peptidase 35
VN1R2 vomeronasal 1 receptor 2
VPS26B vacuolar protein sorting 26 homolog B (S. pombe)
VPS37C vacuolar protein sorting 37 homolog C (S. cerevisiae)
WBP1L WW domain binding protein 1-like
WBSCR16 Williams-Beuren syndrome chromosome region 16
WDR45 WD repeat domain 45
WIPF3 WAS/WASL interacting protein family, member 3
YKT6 YKT6 v-SNARE homolog (S. cerevisiae)
ZDHHC7 zinc finger, DHHC-type containing 7
ZFYVE19 zinc finger, FYVE domain containing 19
ZFYVE27 zinc finger, FYVE domain containing 27
ZNF576 zinc finger protein 576

low expression

Symbol Name
BRD2 bromodomain containing 2
C17ORF80 chromosome 17 open reading frame 80
C2ORF42 chromosome 2 open reading frame 42
CCAR1 cell division cycle and apoptosis regulator 1
FAM120B family with sequence similarity 120B
FBXW8 F-box and WD repeat domain containing 8
LTV1 LTV1 ribosome biogenesis factor
MAP3K4 mitogen-activated protein kinase kinase kinase 4
MDC1 mediator of DNA-damage checkpoint 1
NCOA5 nuclear receptor coactivator 5
PPIG peptidylprolyl isomerase G (cyclophilin G)
PPP1R11 protein phosphatase 1, regulatory (inhibitor) subunit 11
RBBP6 retinoblastoma binding protein 6
RBM26 RNA binding motif protein 26
RIC8B RIC8 guanine nucleotide exchange factor B
RSRC2 arginine/serine-rich coiled-coil 2
TBP TATA box binding protein
THOC2 THO complex 2
TMEM260 transmembrane protein 260
TTC17 tetratricopeptide repeat domain 17
ZCCHC8 zinc finger, CCHC domain containing 8
ZNF140 zinc finger protein 140
ZNF155 zinc finger protein 155
ZNF329 zinc finger protein 329
ZNF638 zinc finger protein 638