Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5459-01A-01R-1503-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Kidney renal clear cell carcinoma_KIRC (The Cancer Genome Atlas)
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326 genes with high or low expression in Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5459-01A-01R-1503-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
ABCA12 ATP-binding cassette, sub-family A (ABC1), member 12
ACRV1 acrosomal vesicle protein 1
ACSM5 acyl-CoA synthetase medium-chain family member 5
ADAM18 ADAM metallopeptidase domain 18
ADAMTS20 ADAM metallopeptidase with thrombospondin type 1 motif, 20
ADCK4 aarF domain containing kinase 4
ADD2 adducin 2 (beta)
ADGRB3 adhesion G protein-coupled receptor B3
ADM adrenomedullin
AGBL4 ATP/GTP binding protein-like 4
AKAP14 A kinase (PRKA) anchor protein 14
ALDH3B1 aldehyde dehydrogenase 3 family, member B1
ALOX12B arachidonate 12-lipoxygenase, 12R type
ALOX5 arachidonate 5-lipoxygenase
ALPL alkaline phosphatase, liver/bone/kidney
ANGPTL4 angiopoietin-like 4
ANXA2R annexin A2 receptor
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1
ASB17 ankyrin repeat and SOCS box containing 17
ASPA aspartoacylase
ASPRV1 aspartic peptidase, retroviral-like 1
ATP8A2 ATPase, aminophospholipid transporter, class I, type 8A, member 2
B3GNT9 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9
BAX BCL2-associated X protein
BCKDK branched chain ketoacid dehydrogenase kinase
BCL2L10 BCL2-like 10 (apoptosis facilitator)
BIRC7 baculoviral IAP repeat containing 7
BOLA1 bolA family member 1
BRCA1 breast cancer 1, early onset
BRCA2 breast cancer 2, early onset
BRE brain and reproductive organ-expressed (TNFRSF1A modulator)
C10ORF10 chromosome 10 open reading frame 10
C11ORF70 chromosome 11 open reading frame 70
C14ORF79 chromosome 14 open reading frame 79
C17ORF105 chromosome 17 open reading frame 105
C17ORF82 chromosome 17 open reading frame 82
C19ORF57 chromosome 19 open reading frame 57
C1ORF56 chromosome 1 open reading frame 56
C2CD4D C2 calcium-dependent domain containing 4D
C6ORF48 chromosome 6 open reading frame 48
CAPN14 calpain 14
CARD10 caspase recruitment domain family, member 10
CBWD5 COBW domain containing 5
CCDC74B coiled-coil domain containing 74B
CCDC8 coiled-coil domain containing 8
CCDC87 coiled-coil domain containing 87
CCNB3 cyclin B3
CCR6 chemokine (C-C motif) receptor 6
CD300A CD300a molecule
CDC45 cell division cycle 45
CDCA7 cell division cycle associated 7
CDK20 cyclin-dependent kinase 20
CDT1 chromatin licensing and DNA replication factor 1
CENPM centromere protein M
CENPU centromere protein U
CHAF1A chromatin assembly factor 1, subunit A (p150)
CHEK1 checkpoint kinase 1
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CIB3 calcium and integrin binding family member 3
CISH cytokine inducible SH2-containing protein
CIT citron rho-interacting serine/threonine kinase
CNTNAP3 contactin associated protein-like 3
COLEC11 collectin sub-family member 11
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
CSPG5 chondroitin sulfate proteoglycan 5 (neuroglycan C)
CYP24A1 cytochrome P450, family 24, subfamily A, polypeptide 1
DCAF12L2 DDB1 and CUL4 associated factor 12-like 2
DDIT4 DNA-damage-inducible transcript 4
DDX43 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43
DHRS7C dehydrogenase/reductase (SDR family) member 7C
DHX37 DEAH (Asp-Glu-Ala-His) box polypeptide 37
DIAPH3 diaphanous-related formin 3
DMBX1 diencephalon/mesencephalon homeobox 1
DMRTC1B DMRT-like family C1B
DOK6 docking protein 6
DPEP3 dipeptidase 3
DRD3 dopamine receptor D3
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila)
DTX1 deltex 1, E3 ubiquitin ligase
E2F1 E2F transcription factor 1
E2F8 E2F transcription factor 8
EBF4 early B-cell factor 4
EDN2 endothelin 2
EEF2 eukaryotic translation elongation factor 2
EFCAB11 EF-hand calcium binding domain 11
EIF3CL eukaryotic translation initiation factor 3, subunit C-like
ELFN2 extracellular leucine-rich repeat and fibronectin type III domain containing 2
EXO1 exonuclease 1
FAM110B family with sequence similarity 110, member B
FAM111B family with sequence similarity 111, member B
FAM120AOS family with sequence similarity 120A opposite strand
FAM159A family with sequence similarity 159, member A
FAM50B family with sequence similarity 50, member B
FAM71C family with sequence similarity 71, member C
FAM86B1 family with sequence similarity 86, member B1
FANCA Fanconi anemia, complementation group A
FARSA phenylalanyl-tRNA synthetase, alpha subunit
FBXO47 F-box protein 47
FDXR ferredoxin reductase
FGB fibrinogen beta chain
FKBPL FK506 binding protein like
FTH1P3 ferritin, heavy polypeptide 1 pseudogene 3
FUZ fuzzy planar cell polarity protein
GALNTL5 polypeptide N-acetylgalactosaminyltransferase-like 5
GDF15 growth differentiation factor 15
GHDC GH3 domain containing
GINS2 GINS complex subunit 2 (Psf2 homolog)
GINS4 GINS complex subunit 4 (Sld5 homolog)
GLB1L3 galactosidase, beta 1-like 3
GLTSCR2 glioma tumor suppressor candidate region gene 2
GNAS-AS1 GNAS antisense RNA 1
GPR62 G protein-coupled receptor 62
GTF2F1 general transcription factor IIF, polypeptide 1, 74kDa
H2BFXP H2B histone family, member X, pseudogene
HAUS4 HAUS augmin-like complex, subunit 4
HBG1 hemoglobin, gamma A
HBG2 hemoglobin, gamma G
HCCAT5 hepatocellular carcinoma associated transcript 5 (non-protein coding)
HELLS helicase, lymphoid-specific
HELQ helicase, POLQ-like
HES1 hes family bHLH transcription factor 1
HEXIM2 hexamethylene bis-acetamide inducible 2
HFM1 HFM1, ATP-dependent DNA helicase homolog (S. cerevisiae)
HILPDA hypoxia inducible lipid droplet-associated
HIPK4 homeodomain interacting protein kinase 4
HIST1H2AB histone cluster 1, H2ab
HIST1H2BO histone cluster 1, H2bo
HIST3H3 histone cluster 3, H3
HLA-C major histocompatibility complex, class I, C
HMOX1 heme oxygenase 1
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1
HPDL 4-hydroxyphenylpyruvate dioxygenase-like
HTR6 5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled
IFNA1 interferon, alpha 1
IGBP1P1 immunoglobulin (CD79A) binding protein 1 pseudogene 1
IGFL4 IGF-like family member 4
IL1RL2 interleukin 1 receptor-like 2
IL27RA interleukin 27 receptor, alpha
INO80B INO80 complex subunit B
IPO4 importin 4
IQCD IQ motif containing D
JUN jun proto-oncogene
JUNB jun B proto-oncogene
KCNIP4 Kv channel interacting protein 4
KDM4E lysine (K)-specific demethylase 4E
KIAA0101 KIAA0101
KIAA1804 mixed lineage kinase 4
KIAA2013 KIAA2013
KNDC1 kinase non-catalytic C-lobe domain (KIND) containing 1
KRTAP10-3 keratin associated protein 10-3
KRTDAP keratinocyte differentiation-associated protein
LHX5 LIM homeobox 5
LIAS lipoic acid synthetase
LINC00094 long intergenic non-protein coding RNA 94
LINC00589 long intergenic non-protein coding RNA 589
LINC01587 long intergenic non-protein coding RNA 1587
LMTK3 lemur tyrosine kinase 3
LOC100132111 uncharacterized LOC100132111
LOC100133669 uncharacterized LOC100133669
LOC100133985 uncharacterized LOC100133985
LOC100270746 uncharacterized LOC100270746
LOC401127 WD repeat domain 5 pseudogene
LOC441454 prothymosin, alpha pseudogene
LOC81691 exonuclease NEF-sp
LRRC4C leucine rich repeat containing 4C
LRRC75A leucine rich repeat containing 75A
LRRC75A-AS1 LRRC75A antisense RNA 1
LY6E lymphocyte antigen 6 complex, locus E
MAP2K1 mitogen-activated protein kinase kinase 1
MCM3 minichromosome maintenance complex component 3
MCM4 minichromosome maintenance complex component 4
MCM5 minichromosome maintenance complex component 5
MCM6 minichromosome maintenance complex component 6
MEGF11 multiple EGF-like-domains 11
METTL12 methyltransferase like 12
METTL21B methyltransferase like 21B
MGARP mitochondria-localized glutamic acid-rich protein
MGME1 mitochondrial genome maintenance exonuclease 1
MND1 meiotic nuclear divisions 1 homolog (S. cerevisiae)
MOAP1 modulator of apoptosis 1
MRGPRE MAS-related GPR, member E
MT1H metallothionein 1H
MTG1 mitochondrial ribosome-associated GTPase 1
MYBPC2 myosin binding protein C, fast type
MYL6B myosin, light chain 6B, alkali, smooth muscle and non-muscle
NACA2 nascent polypeptide-associated complex alpha subunit 2
NACAP1 nascent-polypeptide-associated complex alpha polypeptide pseudogene 1
NCOR1P1 nuclear receptor corepressor 1 pseudogene 1
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NHLRC1 NHL repeat containing E3 ubiquitin protein ligase 1
NKX6-3 NK6 homeobox 3
NOA1 nitric oxide associated 1
NOB1 NIN1/RPN12 binding protein 1 homolog (S. cerevisiae)
NOXA1 NADPH oxidase activator 1
NPAS1 neuronal PAS domain protein 1
NPTX2 neuronal pentraxin II
NRM nurim (nuclear envelope membrane protein)
OOEP oocyte expressed protein
OPLAH 5-oxoprolinase (ATP-hydrolysing)
OR11H6 olfactory receptor, family 11, subfamily H, member 6
OR52E6 olfactory receptor, family 52, subfamily E, member 6
OR6C2 olfactory receptor, family 6, subfamily C, member 2
OR7E37P olfactory receptor, family 7, subfamily E, member 37 pseudogene
ORC1 origin recognition complex, subunit 1
OSM oncostatin M
PABPC4 poly(A) binding protein, cytoplasmic 4 (inducible form)
PACSIN3 protein kinase C and casein kinase substrate in neurons 3
PCDHGA6 protocadherin gamma subfamily A, 6
PHYHD1 phytanoyl-CoA dioxygenase domain containing 1
PIFO primary cilia formation
PIM3 Pim-3 proto-oncogene, serine/threonine kinase
PIWIL2 piwi-like RNA-mediated gene silencing 2
PKMYT1 protein kinase, membrane associated tyrosine/threonine 1
PLEKHG4 pleckstrin homology domain containing, family G (with RhoGef domain) member 4
PLP2 proteolipid protein 2 (colonic epithelium-enriched)
POLD1 polymerase (DNA directed), delta 1, catalytic subunit
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit
POLR2E polymerase (RNA) II (DNA directed) polypeptide E, 25kDa
POMC proopiomelanocortin
PPP1R15A protein phosphatase 1, regulatory subunit 15A
PPP1R3B protein phosphatase 1, regulatory subunit 3B
PRIM1 primase, DNA, polypeptide 1 (49kDa)
PRR18 proline rich 18
PSMC3IP PSMC3 interacting protein
PTCHD4 patched domain containing 4
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
PTPRR protein tyrosine phosphatase, receptor type, R
PYDC1 PYD (pyrin domain) containing 1
QPCT glutaminyl-peptide cyclotransferase
QRFP pyroglutamylated RFamide peptide
RAD54B RAD54 homolog B (S. cerevisiae)
REXO4 REX4, RNA exonuclease 4 homolog (S. cerevisiae)
RFC5 replication factor C (activator 1) 5, 36.5kDa
RGS20 regulator of G-protein signaling 20
RIBC2 RIB43A domain with coiled-coils 2
RIPK4 receptor-interacting serine-threonine kinase 4
RMI2 RecQ mediated genome instability 2
RNASE9 ribonuclease, RNase A family, 9 (non-active)
RNASEH2A ribonuclease H2, subunit A
RNF186 ring finger protein 186
RNF212 ring finger protein 212
RNF5P1 ring finger protein 5, E3 ubiquitin protein ligase pseudogene 1
RPL12 ribosomal protein L12
RPL22 ribosomal protein L22
RPL23 ribosomal protein L23
RPL3 ribosomal protein L3
RPS12 ribosomal protein S12
RPS8 ribosomal protein S8
RPUSD4 RNA pseudouridylate synthase domain containing 4
RSPH14 radial spoke head 14 homolog (Chlamydomonas)
SDHA succinate dehydrogenase complex, subunit A, flavoprotein (Fp)
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SFTA3 surfactant associated 3
SHANK2 SH3 and multiple ankyrin repeat domains 2
SIX3 SIX homeobox 3
SLC22A17 solute carrier family 22, member 17
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5
SLC39A1 solute carrier family 39 (zinc transporter), member 1
SLC43A3 solute carrier family 43, member 3
SLFN13 schlafen family member 13
SMC1B structural maintenance of chromosomes 1B
SNHG5 small nucleolar RNA host gene 5
SNHG7 small nucleolar RNA host gene 7
SNHG8 small nucleolar RNA host gene 8
SOHLH2 spermatogenesis and oogenesis specific basic helix-loop-helix 2
SOX30 SRY (sex determining region Y)-box 30
SPATA17 spermatogenesis associated 17
SPATA7 spermatogenesis associated 7
SPEM1 spermatid maturation 1
SPP1 secreted phosphoprotein 1
SSTR1 somatostatin receptor 1
SSTR4 somatostatin receptor 4
STATH statherin
SUGT1P1 SUGT1 pseudogene 1
SYCE1L synaptonemal complex central element protein 1-like
SYS1-DBNDD2 SYS1-DBNDD2 readthrough (NMD candidate)
TDRD9 tudor domain containing 9
TEX15 testis expressed 15
TICAM1 toll-like receptor adaptor molecule 1
TIGD5 tigger transposable element derived 5
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast)
TMCO4 transmembrane and coiled-coil domains 4
TMEM105 transmembrane protein 105
TMEM121 transmembrane protein 121
TMEM18 transmembrane protein 18
TMEM220 transmembrane protein 220
TMEM91 transmembrane protein 91
TMEM97 transmembrane protein 97
TOMM20L translocase of outer mitochondrial membrane 20 homolog (yeast)-like
TONSL tonsoku-like, DNA repair protein
TRIB3 tribbles pseudokinase 3
TSEN34 TSEN34 tRNA splicing endonuclease subunit
TTC9B tetratricopeptide repeat domain 9B
TYMS thymidylate synthetase
TYMSOS TYMS opposite strand
VCX variable charge, X-linked
WDR64 WD repeat domain 64
WDR76 WD repeat domain 76
WWC2-AS2 WWC2 antisense RNA 2
XKR3 XK, Kell blood group complex subunit-related family, member 3
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1
ZBTB12 zinc finger and BTB domain containing 12
ZBTB42 zinc finger and BTB domain containing 42
ZHX2 zinc fingers and homeoboxes 2
ZNF454 zinc finger protein 454
ZNF581 zinc finger protein 581
ZNF826P zinc finger protein 826, pseudogene
ZWINT ZW10 interacting kinetochore protein

low expression

Symbol Name
ASTE1 asteroid homolog 1 (Drosophila)
DBR1 debranching RNA lariats 1
FBXL12 F-box and leucine-rich repeat protein 12
KPNA1 karyopherin alpha 1 (importin alpha 5)
MSL2 male-specific lethal 2 homolog (Drosophila)
NCBP2 nuclear cap binding protein subunit 2, 20kDa
RYK receptor-like tyrosine kinase
SEC22A SEC22 vesicle trafficking protein homolog A (S. cerevisiae)
SENP2 SUMO1/sentrin/SMT3 specific peptidase 2
VPS8 vacuolar protein sorting 8 homolog (S. cerevisiae)
WDR37 WD repeat domain 37
ZNF256 zinc finger protein 256
ZNF304 zinc finger protein 304
ZNF35 zinc finger protein 35
ZNF543 zinc finger protein 543
ZNF761 zinc finger protein 761
ZNF845 zinc finger protein 845