Kuru Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores 2025
Category disease or phenotype associations
Type disease
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Genes

69 genes co-occuring with the disease Kuru in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset.

Symbol Name Standardized Value
PRNP prion protein 3.61
SPRN shadow of prion protein homolog (zebrafish) 2.346
SNCA synuclein, alpha (non A4 component of amyloid precursor) 2.332
PRND prion protein 2 (dublet) 2.284
MSMB microseminoprotein, beta- 2.277
STMN2 stathmin 2 2.173
APP amyloid beta (A4) precursor protein 2.038
TARDBP TAR DNA binding protein 2.019
ERI3 ERI1 exoribonuclease family member 3 1.938
HTT huntingtin 1.927
ZBTB38 zinc finger and BTB domain containing 38 1.839
MAPT microtubule-associated protein tau 1.815
PEPD peptidase D 1.728
PSEN1 presenilin 1 1.708
PSEN2 presenilin 2 1.702
SCN2A sodium channel, voltage gated, type II alpha subunit 1.694
CPEB1 cytoplasmic polyadenylation element binding protein 1 1.692
RARB retinoic acid receptor, beta 1.682
SOD1 superoxide dismutase 1, soluble 1.665
FUS FUS RNA binding protein 1.658
TXNDC9 thioredoxin domain containing 9 1.655
RASA2 RAS p21 protein activator 2 1.62
APOE apolipoprotein E 1.54
ADGRL3 adhesion G protein-coupled receptor L3 1.516
FYN FYN proto-oncogene, Src family tyrosine kinase 1.444
STIP1 stress-induced phosphoprotein 1 1.431
MTMR7 myotubularin related protein 7 1.428
HSPA4 heat shock 70kDa protein 4 1.417
RPSA ribosomal protein SA 1.386
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta 1.383
GFAP glial fibrillary acidic protein 1.352
C9ORF72 chromosome 9 open reading frame 72 1.351
CHN2 chimerin 2 1.342
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1 1.336
GH1 growth hormone 1 1.325
BACE1 beta-site APP-cleaving enzyme 1 1.323
OR5B3 olfactory receptor, family 5, subfamily B, member 3 1.302
GAL3ST1 galactose-3-O-sulfotransferase 1 1.299
PXDNL peroxidasin-like 1.292
PXDN peroxidasin 1.29
TTR transthyretin 1.285
IAPP islet amyloid polypeptide 1.251
ENO2 enolase 2 (gamma, neuronal) 1.251
NWD2 NACHT and WD repeat domain containing 2 1.249
MGRN1 mahogunin ring finger 1, E3 ubiquitin protein ligase 1.241
ITM2B integral membrane protein 2B 1.235
ADGRG6 adhesion G protein-coupled receptor G6 1.215
CA4 carbonic anhydrase IV 1.201
NEFL neurofilament, light polypeptide 1.183
TRIT1 tRNA isopentenyltransferase 1 1.159
PRKN parkin RBR E3 ubiquitin protein ligase 1.148
TIA1 TIA1 cytotoxic granule-associated RNA binding protein 1.113
MAN2B1 mannosidase, alpha, class 2B, member 1 1.101
PARK7 parkinson protein 7 1.095
OPRD1 opioid receptor, delta 1 1.087
SHOC1 shortage in chiasmata 1 1.079
PDIA3 protein disulfide isomerase family A, member 3 1.077
RBM8A RNA binding motif protein 8A 1.075
LRP1 low density lipoprotein receptor-related protein 1 1.054
UBQLN2 ubiquilin 2 1.054
FLOT1 flotillin 1 1.054
MAN2A1 mannosidase, alpha, class 2A, member 1 1.043
PINK1 PTEN induced putative kinase 1 1.039
CLU clusterin 1.035
CPNE3 copine III 1.034
S100B S100 calcium binding protein B 1.034
HSPA8 heat shock 70kDa protein 8 1.032
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 1.021
NCSTN nicastrin 1.013