Kyphosis Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores 2025
Category disease or phenotype associations
Type disease
Description Exaggerated anterior convexity of the thoracic vertebral column. (Human Phenotype Ontology, HP_0002808)
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Genes

515 genes co-occuring with the disease Kyphosis in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset.

Symbol Name Standardized Value
GALNS galactosamine (N-acetyl)-6-sulfatase 2.506
CRP C-reactive protein, pentraxin-related 2.372
UTRN utrophin 2.292
PTH parathyroid hormone 2.287
IDUA iduronidase, alpha-L- 2.224
COL2A1 collagen, type II, alpha 1 2.198
FBN1 fibrillin 1 2.194
BMP2 bone morphogenetic protein 2 2.171
NF1 neurofibromin 1 2.162
FGFR3 fibroblast growth factor receptor 3 2.157
CRTAP cartilage associated protein 2.11
ZMPSTE24 zinc metallopeptidase STE24 2.11
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11 2.072
COL1A1 collagen, type I, alpha 1 2.07
BGLAP bone gamma-carboxyglutamate (gla) protein 2.063
IGF1 insulin-like growth factor 1 (somatomedin C) 2.053
COL1A2 collagen, type I, alpha 2 2.025
GLB1 galactosidase, beta 1 2.008
CKM creatine kinase, muscle 2.004
CHST14 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 14 1.976
FGF23 fibroblast growth factor 23 1.956
ERCC1 excision repair cross-complementation group 1 1.924
ACAN aggrecan 1.922
SP7 Sp7 transcription factor 1.903
ARSB arylsulfatase B 1.895
IFITM5 interferon induced transmembrane protein 5 1.893
SOST sclerostin 1.891
B4GALT7 xylosylprotein beta 1,4-galactosyltransferase, polypeptide 7 1.888
POLG polymerase (DNA directed), gamma 1.876
CKMT2 creatine kinase, mitochondrial 2 (sarcomeric) 1.874
P3H1 prolyl 3-hydroxylase 1 1.873
CKMT1B creatine kinase, mitochondrial 1B 1.87
CKB creatine kinase, brain 1.87
RUNX2 runt-related transcription factor 2 1.866
KL klotho 1.854
PAX1 paired box 1 1.853
NPPC natriuretic peptide C 1.852
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b 1.851
IHH indian hedgehog 1.846
GFAP glial fibrillary acidic protein 1.84
TBX6 T-box 6 1.84
FLNB filamin B, beta 1.837
ALB albumin 1.836
GAPDH glyceraldehyde-3-phosphate dehydrogenase 1.827
TBPL1 TBP-like 1 1.822
PLOD1 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 1.819
MCAT malonyl CoA:ACP acyltransferase (mitochondrial) 1.809
TGFB1 transforming growth factor, beta 1 1.805
IDS iduronate 2-sulfatase 1.797
ACTB actin, beta 1.796
PAX7 paired box 7 1.784
MESP2 mesoderm posterior basic helix-loop-helix transcription factor 2 1.782
FKBP10 FK506 binding protein 10, 65 kDa 1.779
SOX9 SRY (sex determining region Y)-box 9 1.771
MECP2 methyl CpG binding protein 2 1.77
ERCC2 excision repair cross-complementation group 2 1.769
TNF tumor necrosis factor 1.764
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) 1.763
SH3PXD2B SH3 and PX domains 2B 1.753
IL6 interleukin 6 1.748
PLS3 plastin 3 1.734
AIF1 allograft inflammatory factor 1 1.728
MYH14 myosin, heavy chain 14, non-muscle 1.728
ERCC8 excision repair cross-complementation group 8 1.716
ACP5 acid phosphatase 5, tartrate resistant 1.714
CTSK cathepsin K 1.713
SRD5A3 steroid 5 alpha-reductase 3 1.703
GNPTAB N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits 1.687
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha 1.687
TP53 tumor protein p53 1.682
DMD dystrophin 1.678
XYLT2 xylosyltransferase II 1.674
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1) 1.674
FBN2 fibrillin 2 1.672
COL10A1 collagen, type X, alpha 1 1.67
B3GAT3 beta-1,3-glucuronyltransferase 3 1.669
ATXN1 ataxin 1 1.658
CCN6 cellular communication network factor 6 1.649
ELN elastin 1.644
INS insulin 1.641
COL11A2 collagen, type XI, alpha 2 1.638
XPA xeroderma pigmentosum, complementation group A 1.632
TWNK twinkle mtDNA helicase 1.632
CDKN2A cyclin-dependent kinase inhibitor 2A 1.63
RBFOX3 RNA binding protein, fox-1 homolog (C. elegans) 3 1.627
IL1B interleukin 1, beta 1.627
DCN decorin 1.622
CHRNG cholinergic receptor, nicotinic, gamma (muscle) 1.62
SIRT6 sirtuin 6 1.615
PXDN peroxidasin 1.613
PXDNL peroxidasin-like 1.612
PHEX phosphate regulating endopeptidase homolog, X-linked 1.609
ALPL alkaline phosphatase, liver/bone/kidney 1.603
MTOR mechanistic target of rapamycin (serine/threonine kinase) 1.599
RYR1 ryanodine receptor 1 (skeletal) 1.597
TMEM38B transmembrane protein 38B 1.596
CHST3 carbohydrate (chondroitin 6) sulfotransferase 3 1.589
MYOG myogenin (myogenic factor 4) 1.589
LRP5 low density lipoprotein receptor-related protein 5 1.585
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 1.581
TFAM transcription factor A, mitochondrial 1.58
MYH4 myosin, heavy chain 4, skeletal muscle 1.577
PPIB peptidylprolyl isomerase B (cyclophilin B) 1.571
GTF2H5 general transcription factor IIH, polypeptide 5 1.57
SMAD9 SMAD family member 9 1.566
DSE dermatan sulfate epimerase 1.564
ERCC6 excision repair cross-complementation group 6 1.564
WNT1 wingless-type MMTV integration site family, member 1 1.561
SIRT7 sirtuin 7 1.561
COL9A3 collagen, type IX, alpha 3 1.559
SLC39A6 solute carrier family 39 (zinc transporter), member 6 1.547
MSTN myostatin 1.544
CALB1 calbindin 1, 28kDa 1.542
B3GALT6 UDP-Gal:betaGal beta 1,3-galactosyltransferase polypeptide 6 1.542
DNAH8 dynein, axonemal, heavy chain 8 1.541
GUSB glucuronidase, beta 1.541
ERCC3 excision repair cross-complementation group 3 1.537
MYH6 myosin, heavy chain 6, cardiac muscle, alpha 1.536
RIPPLY2 ripply transcriptional repressor 2 1.535
COL9A1 collagen, type IX, alpha 1 1.531
MFN2 mitofusin 2 1.53
FKBP14 FK506 binding protein 14, 22 kDa 1.53
SLC26A2 solute carrier family 26 (anion exchanger), member 2 1.53
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B 1.528
WRN Werner syndrome, RecQ helicase-like 1.523
ELP1 elongator acetyltransferase complex subunit 1 1.521
SLC34A1 solute carrier family 34 (type II sodium/phosphate cotransporter), member 1 1.52
SSPN sarcospan 1.513
LMNA lamin A/C 1.506
TRIM63 tripartite motif containing 63, E3 ubiquitin protein ligase 1.506
FBXO32 F-box protein 32 1.497
MATK megakaryocyte-associated tyrosine kinase 1.495
SIRT1 sirtuin 1 1.492
ESR1 estrogen receptor 1 1.481
XYLT1 xylosyltransferase I 1.479
PTHLH parathyroid hormone-like hormone 1.478
MYOD1 myogenic differentiation 1 1.476
LOX lysyl oxidase 1.471
SOD1 superoxide dismutase 1, soluble 1.47
LAMA2 laminin, alpha 2 1.469
TARDBP TAR DNA binding protein 1.468
AKT1 v-akt murine thymoma viral oncogene homolog 1 1.468
TNNT1 troponin T type 1 (skeletal, slow) 1.466
SUMF1 sulfatase modifying factor 1 1.463
MSGN1 mesogenin 1 1.459
MTM1 myotubularin 1 1.457
TRAPPC2 trafficking protein particle complex 2 1.454
JUN jun proto-oncogene 1.451
SPP1 secreted phosphoprotein 1 1.448
MYH3 myosin, heavy chain 3, skeletal muscle, embryonic 1.444
LTBP3 latent transforming growth factor beta binding protein 3 1.441
FGF8 fibroblast growth factor 8 (androgen-induced) 1.441
CANT1 calcium activated nucleotidase 1 1.44
COL11A1 collagen, type XI, alpha 1 1.439
DYSF dysferlin 1.437
IL1A interleukin 1, alpha 1.434
STRADA STE20-related kinase adaptor alpha 1.434
OPA1 optic atrophy 1 (autosomal dominant) 1.433
NAGLU N-acetylglucosaminidase, alpha 1.431
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 1.424
CYC1 cytochrome c-1 1.418
FGF18 fibroblast growth factor 18 1.418
HSPG2 heparan sulfate proteoglycan 2 1.417
NPC1 Niemann-Pick disease, type C1 1.415
NFIX nuclear factor I/X (CCAAT-binding transcription factor) 1.415
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 1.413
BMP1 bone morphogenetic protein 1 1.409
SMAD3 SMAD family member 3 1.407
GH1 growth hormone 1 1.401
SNCA synuclein, alpha (non A4 component of amyloid precursor) 1.399
FGF3 fibroblast growth factor 3 1.396
PKD2L1 polycystic kidney disease 2-like 1 1.391
AGRN agrin 1.391
COL12A1 collagen, type XII, alpha 1 1.39
OSTN osteocrin 1.384
RGS3 regulator of G-protein signaling 3 1.383
PTPRC protein tyrosine phosphatase, receptor type, C 1.382
FGF9 fibroblast growth factor 9 1.378
COL5A1 collagen, type V, alpha 1 1.375
FGF21 fibroblast growth factor 21 1.374
PRL prolactin 1.373
COL6A1 collagen, type VI, alpha 1 1.373
FGF4 fibroblast growth factor 4 1.372
CD4 CD4 molecule 1.371
BGN biglycan 1.37
MBTPS1 membrane-bound transcription factor peptidase, site 1 1.37
GDF5 growth differentiation factor 5 1.37
SMR3A submaxillary gland androgen regulated protein 3A 1.369
ATP12A ATPase, H+/K+ transporting, nongastric, alpha polypeptide 1.368
GDF6 growth differentiation factor 6 1.368
ATP4A ATPase, H+/K+ exchanging, alpha polypeptide 1.368
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) 1.367
FGF10 fibroblast growth factor 10 1.367
VRTN vertebrae development associated 1.367
RFK riboflavin kinase 1.363
POMC proopiomelanocortin 1.358
SLC39A13 solute carrier family 39 (zinc transporter), member 13 1.356
FAM20B family with sequence similarity 20, member B 1.356
COL5A2 collagen, type V, alpha 2 1.356
NPR2 natriuretic peptide receptor 2 1.355
PTPN11 protein tyrosine phosphatase, non-receptor type 11 1.355
MTR 5-methyltetrahydrofolate-homocysteine methyltransferase 1.354
FGF17 fibroblast growth factor 17 1.353
TTN titin 1.353
GPT glutamic-pyruvate transaminase (alanine aminotransferase) 1.353
EGF epidermal growth factor 1.352
FGF7 fibroblast growth factor 7 1.35
SMN2 survival of motor neuron 2, centromeric 1.349
MYL1 myosin, light chain 1, alkali; skeletal, fast 1.348
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) 1.347
CLMP CXADR-like membrane protein 1.347
CASP3 caspase 3, apoptosis-related cysteine peptidase 1.346
LEP leptin 1.345
PIEZO2 piezo-type mechanosensitive ion channel component 2 1.345
LTBP2 latent transforming growth factor beta binding protein 2 1.344
HGD homogentisate 1,2-dioxygenase 1.34
LMNB1 lamin B1 1.338
FN1 fibronectin 1 1.338
PINK1 PTEN induced putative kinase 1 1.337
BMP4 bone morphogenetic protein 4 1.335
FGF6 fibroblast growth factor 6 1.334
IBSP integrin-binding sialoprotein 1.334
SMN1 survival of motor neuron 1, telomeric 1.332
ATM ATM serine/threonine kinase 1.331
GNPTG N-acetylglucosamine-1-phosphate transferase, gamma subunit 1.331
CREB3L1 cAMP responsive element binding protein 3-like 1 1.33
ACTA1 actin, alpha 1, skeletal muscle 1.33
LETM1 leucine zipper-EF-hand containing transmembrane protein 1 1.328
FGF5 fibroblast growth factor 5 1.326
SGSH N-sulfoglucosamine sulfohydrolase 1.326
MMP13 matrix metallopeptidase 13 1.325
FGF20 fibroblast growth factor 20 1.323
NDUFS4 NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase) 1.322
H3-3B H3.3 histone B 1.322
H3-4 H3.4 histone, cluster member 1.321
FGF22 fibroblast growth factor 22 1.319
CHAT choline O-acetyltransferase 1.319
SQSTM1 sequestosome 1 1.318
FGF16 fibroblast growth factor 16 1.318
H3-5 H3.5 histone 1.315
NEB nebulin 1.315
H3C13 H3 clustered histone 13 1.314
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2 1.313
MYF5 myogenic factor 5 1.313
APP amyloid beta (A4) precursor protein 1.312
CAPN3 calpain 3, (p94) 1.311
H3C12 H3 clustered histone 12 1.31
IFNG interferon, gamma 1.309
CD68 CD68 molecule 1.307
MYH2 myosin, heavy chain 2, skeletal muscle, adult 1.306
PRKN parkin RBR E3 ubiquitin protein ligase 1.303
SLC34A3 solute carrier family 34 (type II sodium/phosphate cotransporter), member 3 1.302
CTSA cathepsin A 1.301
ATXN7 ataxin 7 1.299
PRNP prion protein 1.299
MAPK3 mitogen-activated protein kinase 3 1.299
TGFBR1 transforming growth factor, beta receptor 1 1.297
MYBPC1 myosin binding protein C, slow type 1.297
COMP cartilage oligomeric matrix protein 1.296
TP53BP1 tumor protein p53 binding protein 1 1.294
TRPV4 transient receptor potential cation channel, subfamily V, member 4 1.294
CLEC3B C-type lectin domain family 3, member B 1.294
SOX6 SRY (sex determining region Y)-box 6 1.293
MFF mitochondrial fission factor 1.291
FOXO3 forkhead box O3 1.29
SMAD2 SMAD family member 2 1.289
ALMS1 Alstrom syndrome protein 1 1.288
ONECUT2 one cut homeobox 2 1.288
CAMK2A calcium/calmodulin-dependent protein kinase II alpha 1.286
SHOX short stature homeobox 1.285
DKK1 dickkopf WNT signaling pathway inhibitor 1 1.284
MYH8 myosin, heavy chain 8, skeletal muscle, perinatal 1.281
SOX5 SRY (sex determining region Y)-box 5 1.28
NES nestin 1.277
EXTL3 exostosin-like glycosyltransferase 3 1.271
FMOD fibromodulin 1.271
SHH sonic hedgehog 1.265
MAGEL2 melanoma antigen family L2 1.265
GH2 growth hormone 2 1.265
POTEF POTE ankyrin domain family, member F 1.262
DNM2 dynamin 2 1.26
SGCA sarcoglycan, alpha (50kDa dystrophin-associated glycoprotein) 1.258
MUSK muscle, skeletal, receptor tyrosine kinase 1.258
COL9A2 collagen, type IX, alpha 2 1.254
QRFPR pyroglutamylated RFamide peptide receptor 1.252
FGF2 fibroblast growth factor 2 (basic) 1.251
SUPV3L1 suppressor of var1, 3-like 1 (S. cerevisiae) 1.251
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1 1.251
SELENON selenoprotein N 1.25
COL3A1 collagen, type III, alpha 1 1.244
FDPS farnesyl diphosphate synthase 1.244
NDUFB8 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19kDa 1.244
UVSSA UV-stimulated scaffold protein A 1.243
NKX3-2 NK3 homeobox 2 1.243
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator 1.241
SIRT2 sirtuin 2 1.239
ATG5 autophagy related 5 1.239
TBP TATA box binding protein 1.238
BDNF brain-derived neurotrophic factor 1.238
ADAMTS4 ADAM metallopeptidase with thrombospondin type 1 motif, 4 1.238
CHRNA1 cholinergic receptor, nicotinic, alpha 1 (muscle) 1.232
FOS FBJ murine osteosarcoma viral oncogene homolog 1.231
OXT oxytocin/neurophysin I prepropeptide 1.228
GDF3 growth differentiation factor 3 1.225
PTH1R parathyroid hormone 1 receptor 1.225
PLEC plectin 1.224
TH tyrosine hydroxylase 1.223
DLL3 delta-like 3 (Drosophila) 1.223
CHRND cholinergic receptor, nicotinic, delta (muscle) 1.223
MEF2C myocyte enhancer factor 2C 1.222
ATXN1L ataxin 1-like 1.221
MMP9 matrix metallopeptidase 9 1.22
MYOT myotilin 1.22
CYCS cytochrome c, somatic 1.218
HPRT1 hypoxanthine phosphoribosyltransferase 1 1.217
FLNC filamin C, gamma 1.217
TRIM8 tripartite motif containing 8 1.215
CD8A CD8a molecule 1.214
CHRNB1 cholinergic receptor, nicotinic, beta 1 (muscle) 1.211
GHR growth hormone receptor 1.21
SPARC secreted protein, acidic, cysteine-rich (osteonectin) 1.204
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 1.204
MYH7 myosin, heavy chain 7, cardiac muscle, beta 1.203
PNPLA8 patatin-like phospholipase domain containing 8 1.202
LCK LCK proto-oncogene, Src family tyrosine kinase 1.2
MBTPS2 membrane-bound transcription factor peptidase, site 2 1.198
RAPSN receptor-associated protein of the synapse 1.198
ACE angiotensin I converting enzyme 1.195
EMD emerin 1.195
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog 1.194
CD34 CD34 molecule 1.193
POLR1E polymerase (RNA) I polypeptide E, 53kDa 1.193
SYN1 synapsin I 1.193
TGFB3 transforming growth factor, beta 3 1.192
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 1.189
FGFR1 fibroblast growth factor receptor 1 1.188
ZNF106 zinc finger protein 106 1.187
SGCD sarcoglycan, delta (35kDa dystrophin-associated glycoprotein) 1.187
ATG7 autophagy related 7 1.184
BMP7 bone morphogenetic protein 7 1.183
FKRP fukutin related protein 1.18
FUCA1 fucosidase, alpha-L- 1, tissue 1.177
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 1.174
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 1.173
HES7 hes family bHLH transcription factor 7 1.172
MMP3 matrix metallopeptidase 3 1.171
SGCG sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) 1.171
IGFBP3 insulin-like growth factor binding protein 3 1.17
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) 1.17
SLC35A3 solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 1.168
AFG3L2 AFG3-like AAA ATPase 2 1.165
SIRT3 sirtuin 3 1.164
ACVR1 activin A receptor, type I 1.163
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1 1.163
DOC2A double C2-like domains, alpha 1.157
MFN1 mitofusin 1 1.157
SOD2 superoxide dismutase 2, mitochondrial 1.157
SLC18A3 solute carrier family 18 (vesicular acetylcholine transporter), member 3 1.156
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 1.155
EMP1 epithelial membrane protein 1 1.152
MAPT microtubule-associated protein tau 1.149
HSPA4 heat shock 70kDa protein 4 1.148
MEPE matrix extracellular phosphoglycoprotein 1.147
GNS glucosamine (N-acetyl)-6-sulfatase 1.147
SSBP1 single-stranded DNA binding protein 1, mitochondrial 1.147
SV2A synaptic vesicle glycoprotein 2A 1.145
EXT1 exostosin glycosyltransferase 1 1.145
FMR1 fragile X mental retardation 1 1.143
SRC SRC proto-oncogene, non-receptor tyrosine kinase 1.143
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 1.139
SYNE1 spectrin repeat containing, nuclear envelope 1 1.137
SPG7 spastic paraplegia 7 (pure and complicated autosomal recessive) 1.135
CAV3 caveolin 3 1.134
SOX2 SRY (sex determining region Y)-box 2 1.133
TAF8 TAF8 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 43kDa 1.133
BCS1L BC1 (ubiquinol-cytochrome c reductase) synthesis-like 1.133
CACNA1E calcium channel, voltage-dependent, R type, alpha 1E subunit 1.133
TAC1 tachykinin, precursor 1 1.132
PPARGC1B peroxisome proliferator-activated receptor gamma, coactivator 1 beta 1.132
APTX aprataxin 1.131
NDUFA10 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10, 42kDa 1.131
IL10 interleukin 10 1.125
CSH1 chorionic somatomammotropin hormone 1 (placental lactogen) 1.125
UQCRC2 ubiquinol-cytochrome c reductase core protein II 1.125
LBX1 ladybird homeobox 1 1.123
SYP synaptophysin 1.122
RNMT RNA (guanine-7-) methyltransferase 1.118
CHIT1 chitinase 1 (chitotriosidase) 1.115
MEOX1 mesenchyme homeobox 1 1.115
SIM1 single-minded family bHLH transcription factor 1 1.115
NDUFAF4 NADH dehydrogenase (ubiquinone) complex I, assembly factor 4 1.114
IL17A interleukin 17A 1.113
UCP1 uncoupling protein 1 (mitochondrial, proton carrier) 1.113
ZBTB20 zinc finger and BTB domain containing 20 1.111
MSMB microseminoprotein, beta- 1.111
ADGRG6 adhesion G protein-coupled receptor G6 1.109
COL6A3 collagen, type VI, alpha 3 1.108
LRP6 low density lipoprotein receptor-related protein 6 1.107
HTT huntingtin 1.107
VCP valosin containing protein 1.105
THY1 Thy-1 cell surface antigen 1.103
CSH2 chorionic somatomammotropin hormone 2 1.101
ATP2A1 ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 1.101
MYH1 myosin, heavy chain 1, skeletal muscle, adult 1.099
LONP1 lon peptidase 1, mitochondrial 1.099
PAX6 paired box 6 1.099
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 1.098
SEC24D SEC24 family member D 1.097
CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1 1.097
PECAM1 platelet/endothelial cell adhesion molecule 1 1.096
PPARG peroxisome proliferator-activated receptor gamma 1.096
TFRC transferrin receptor 1.093
CHD7 chromodomain helicase DNA binding protein 7 1.092
LEMD3 LEM domain containing 3 1.091
TFEB transcription factor EB 1.089
NTMT1 N-terminal Xaa-Pro-Lys N-methyltransferase 1 1.089
FOXO1 forkhead box O1 1.088
ADAMTS18 ADAM metallopeptidase with thrombospondin type 1 motif, 18 1.088
BMPR1B bone morphogenetic protein receptor, type IB 1.086
BAG3 BCL2-associated athanogene 3 1.082
POLG2 polymerase (DNA directed), gamma 2, accessory subunit 1.081
ZBTB40 zinc finger and BTB domain containing 40 1.081
ATE1 arginyltransferase 1 1.079
NPC2 Niemann-Pick disease, type C2 1.077
OTX2 orthodenticle homeobox 2 1.076
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 1.075
RPTOR regulatory associated protein of MTOR, complex 1 1.074
COL27A1 collagen, type XXVII, alpha 1 1.074
RIPPLY1 ripply transcriptional repressor 1 1.074
EDN3 endothelin 3 1.073
POLRMT polymerase (RNA) mitochondrial (DNA directed) 1.072
FUS FUS RNA binding protein 1.07
CALM3 calmodulin 3 (phosphorylase kinase, delta) 1.07
MAP2K1 mitogen-activated protein kinase kinase 1 1.07
MYC v-myc avian myelocytomatosis viral oncogene homolog 1.069
ADAMTS2 ADAM metallopeptidase with thrombospondin type 1 motif, 2 1.069
OLIG2 oligodendrocyte lineage transcription factor 2 1.069
TOMM20 translocase of outer mitochondrial membrane 20 homolog (yeast) 1.068
ANKRD11 ankyrin repeat domain 11 1.068
PTP4A2 protein tyrosine phosphatase type IVA, member 2 1.067
RBM17 RNA binding motif protein 17 1.067
CHRD chordin 1.064
UNCX UNC homeobox 1.064
TMEM11 transmembrane protein 11 1.06
ACBD5 acyl-CoA binding domain containing 5 1.059
UBE3A ubiquitin protein ligase E3A 1.057
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 1.056
MPLKIP M-phase specific PLK1 interacting protein 1.056
PVALB parvalbumin 1.053
BECN1 beclin 1, autophagy related 1.052
DAO D-amino-acid oxidase 1.051
GNAS GNAS complex locus 1.051
CDH7 cadherin 7, type 2 1.051
FLNA filamin A, alpha 1.049
DUX4 double homeobox 4 1.049
SLN sarcolipin 1.047
CD3E CD3e molecule, epsilon (CD3-TCR complex) 1.047
FGFR2 fibroblast growth factor receptor 2 1.046
BUB3 BUB3 mitotic checkpoint protein 1.046
CDH20 cadherin 20, type 2 1.044
VDAC1 voltage-dependent anion channel 1 1.044
FXN frataxin 1.042
PCNT pericentrin 1.042
CDKL5 cyclin-dependent kinase-like 5 1.041
NOG noggin 1.041
ACO1 aconitase 1, soluble 1.04
MKX mohawk homeobox 1.039
BICD2 bicaudal D homolog 2 (Drosophila) 1.036
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 1.035
GALC galactosylceramidase 1.033
NOTCH2 notch 2 1.033
NPR3 natriuretic peptide receptor 3 1.033
KBTBD13 kelch repeat and BTB (POZ) domain containing 13 1.032
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5 1.031
ADAMTSL2 ADAMTS-like 2 1.029
F2 coagulation factor II (thrombin) 1.029
CCN2 cellular communication network factor 2 1.028
COX4I1 cytochrome c oxidase subunit IV isoform 1 1.027
SNRPN small nuclear ribonucleoprotein polypeptide N 1.025
WNT3A wingless-type MMTV integration site family, member 3A 1.025
PRRX1 paired related homeobox 1 1.024
ATRX alpha thalassemia/mental retardation syndrome X-linked 1.024
CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit 1.021
HSPB8 heat shock 22kDa protein 8 1.02
VCL vinculin 1.02
TGFB2 transforming growth factor, beta 2 1.02
ANK2 ankyrin 2, neuronal 1.02
NDUFV1 NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa 1.018
ULK1 unc-51 like autophagy activating kinase 1 1.018
CALML4 calmodulin-like 4 1.016
SOS1 son of sevenless homolog 1 (Drosophila) 1.016
CALML5 calmodulin-like 5 1.013
SST somatostatin 1.013
SCUBE3 signal peptide, CUB domain, EGF-like 3 1.011
LUM lumican 1.01
BCL2 B-cell CLL/lymphoma 2 1.009
F3 coagulation factor III (thromboplastin, tissue factor) 1.009
SUN1 Sad1 and UNC84 domain containing 1 1.008
THBS2 thrombospondin 2 1.008
GDNF glial cell derived neurotrophic factor 1.007
LRRK1 leucine-rich repeat kinase 1 1.007
POC5 POC5 centriolar protein 1.007
FRG2 FSHD region gene 2 1.006
COL6A2 collagen, type VI, alpha 2 1.006
CUL4B cullin 4B 1.006
STAC3 SH3 and cysteine rich domain 3 1.006
ZDHHC13 zinc finger, DHHC-type containing 13 1.006
ADAMTS3 ADAM metallopeptidase with thrombospondin type 1 motif, 3 1.004
PRKG2 protein kinase, cGMP-dependent, type II 1.004
PAX9 paired box 9 1.003
TERT telomerase reverse transcriptase 1.003
CSF1 colony stimulating factor 1 (macrophage) 1.003
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta 1.002
CALML6 calmodulin-like 6 1.0
MAP1LC3B microtubule-associated protein 1 light chain 3 beta 1.0