L-363 Gene Set

Dataset COSMIC Cell Line Gene Mutation Profiles
Category genomics
Type cell line
Description Multiple myeloma cell line expressing syndecan-1. (BRENDA Tissue and Enzyme Source Ontology, BTO_0003308)
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Genes

427 genes mutated in the L-363 cell line from the COSMIC Cell Line Gene Mutation Profiles dataset.

Symbol Name
ABHD12 abhydrolase domain containing 12
ABHD4 abhydrolase domain containing 4
ABI3BP ABI family, member 3 (NESH) binding protein
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase
ACACA acetyl-CoA carboxylase alpha
ACTL9 actin-like 9
ACYP2 acylphosphatase 2, muscle type
ADAM12 ADAM metallopeptidase domain 12
ADAM19 ADAM metallopeptidase domain 19
ADAMTS20 ADAM metallopeptidase with thrombospondin type 1 motif, 20
ADGRF1 adhesion G protein-coupled receptor F1
ADGRF5 adhesion G protein-coupled receptor F5
ADGRG4 adhesion G protein-coupled receptor G4
ADRA1A adrenoceptor alpha 1A
ADRA1B adrenoceptor alpha 1B
AGBL1 ATP/GTP binding protein-like 1
AGRN agrin
AKAP11 A kinase (PRKA) anchor protein 11
AKIP1 A kinase (PRKA) interacting protein 1
ALDH1L1 aldehyde dehydrogenase 1 family, member L1
ALDH1L2 aldehyde dehydrogenase 1 family, member L2
ANK2 ankyrin 2, neuronal
ANK3 ankyrin 3, node of Ranvier (ankyrin G)
ANKLE1 ankyrin repeat and LEM domain containing 1
ANKRD17 ankyrin repeat domain 17
ANO1 anoctamin 1, calcium activated chloride channel
AOX1 aldehyde oxidase 1
AP5Z1 adaptor-related protein complex 5, zeta 1 subunit
APAF1 apoptotic peptidase activating factor 1
APLNR apelin receptor
APOA5 apolipoprotein A-V
APOD apolipoprotein D
APOL4 apolipoprotein L, 4
ARHGAP12 Rho GTPase activating protein 12
ARHGAP15 Rho GTPase activating protein 15
ARHGAP40 Rho GTPase activating protein 40
ARHGEF11 Rho guanine nucleotide exchange factor (GEF) 11
ARID1A AT rich interactive domain 1A (SWI-like)
ASF1B anti-silencing function 1B histone chaperone
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila)
ATG2A autophagy related 2A
ATP8B4 ATPase, class I, type 8B, member 4
B3GNT6 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 6
B4GALNT2 beta-1,4-N-acetyl-galactosaminyl transferase 2
BCAR1 breast cancer anti-estrogen resistance 1
BCR breakpoint cluster region
BIRC3 baculoviral IAP repeat containing 3
BMS1 BMS1 ribosome biogenesis factor
BRD1 bromodomain containing 1
BRPF1 bromodomain and PHD finger containing, 1
C3 complement component 3
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit
CAND1 cullin-associated and neddylation-dissociated 1
CAPN8 calpain 8
CCDC40 coiled-coil domain containing 40
CCT4 chaperonin containing TCP1, subunit 4 (delta)
CD53 CD53 molecule
CDON cell adhesion associated, oncogene regulated
CECR2 cat eye syndrome chromosome region, candidate 2
CENPF centromere protein F, 350/400kDa
CEP68 centrosomal protein 68kDa
CEP97 centrosomal protein 97kDa
CFHR3 complement factor H-related 3
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CHD1 chromodomain helicase DNA binding protein 1
CHST10 carbohydrate sulfotransferase 10
CHST4 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4
CLCN6 chloride channel, voltage-sensitive 6
CLK4 CDC-like kinase 4
CMKLR1 chemerin chemokine-like receptor 1
CNGA3 cyclic nucleotide gated channel alpha 3
CNR2 cannabinoid receptor 2 (macrophage)
CNTN5 contactin 5
COG2 component of oligomeric golgi complex 2
COL11A1 collagen, type XI, alpha 1
COL16A1 collagen, type XVI, alpha 1
COL6A3 collagen, type VI, alpha 3
COLGALT2 collagen beta(1-O)galactosyltransferase 2
COPZ1 coatomer protein complex, subunit zeta 1
CORIN corin, serine peptidase
CREBBP CREB binding protein
CRTAC1 cartilage acidic protein 1
CSMD1 CUB and Sushi multiple domains 1
CSPP1 centrosome and spindle pole associated protein 1
CTSE cathepsin E
CUL9 cullin 9
CYP2C8 cytochrome P450, family 2, subfamily C, polypeptide 8
CYP4V2 cytochrome P450, family 4, subfamily V, polypeptide 2
DAD1 defender against cell death 1
DBR1 debranching RNA lariats 1
DCAF13 DDB1 and CUL4 associated factor 13
DCDC5 doublecortin domain containing 5
DDX11 DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11
DDX25 DEAD (Asp-Glu-Ala-Asp) box helicase 25
DEFB127 defensin, beta 127
DENND2D DENN/MADD domain containing 2D
DHRS7C dehydrogenase/reductase (SDR family) member 7C
DHX16 DEAH (Asp-Glu-Ala-His) box polypeptide 16
DHX38 DEAH (Asp-Glu-Ala-His) box polypeptide 38
DIDO1 death inducer-obliterator 1
DISP2 dispatched homolog 2 (Drosophila)
DNAH1 dynein, axonemal, heavy chain 1
DNAH11 dynein, axonemal, heavy chain 11
DNAH14 dynein, axonemal, heavy chain 14
DNAH17 dynein, axonemal, heavy chain 17
DNAJC27 DnaJ (Hsp40) homolog, subfamily C, member 27
DNAJC30 DnaJ (Hsp40) homolog, subfamily C, member 30
DNM3 dynamin 3
DPH3 diphthamide biosynthesis 3
DPYSL4 dihydropyrimidinase-like 4
DXO decapping exoribonuclease
DYNC1I1 dynein, cytoplasmic 1, intermediate chain 1
DYNC1LI1 dynein, cytoplasmic 1, light intermediate chain 1
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
EAF2 ELL associated factor 2
EEA1 early endosome antigen 1
EFCAB9 EF-hand calcium binding domain 9
EIF2AK4 eukaryotic translation initiation factor 2 alpha kinase 4
EIF3A eukaryotic translation initiation factor 3, subunit A
EIF3CL eukaryotic translation initiation factor 3, subunit C-like
EIF4G3 eukaryotic translation initiation factor 4 gamma, 3
EIF5B eukaryotic translation initiation factor 5B
ELAVL1 ELAV like RNA binding protein 1
ELFN2 extracellular leucine-rich repeat and fibronectin type III domain containing 2
EMC8 ER membrane protein complex subunit 8
EML4 echinoderm microtubule associated protein like 4
ENAM enamelin
EPB41L4A erythrocyte membrane protein band 4.1 like 4A
ERBB3 erb-b2 receptor tyrosine kinase 3
ERICH6B glutamate-rich 6B
ESPL1 extra spindle pole bodies homolog 1 (S. cerevisiae)
FAM193A family with sequence similarity 193, member A
FAM3B family with sequence similarity 3, member B
FAM81A family with sequence similarity 81, member A
FAM89A family with sequence similarity 89, member A
FANCA Fanconi anemia, complementation group A
FANCD2 Fanconi anemia, complementation group D2
FANCI Fanconi anemia, complementation group I
FBN3 fibrillin 3
FBXL6 F-box and leucine-rich repeat protein 6
FGR FGR proto-oncogene, Src family tyrosine kinase
FHAD1 forkhead-associated (FHA) phosphopeptide binding domain 1
FIGLA folliculogenesis specific basic helix-loop-helix
FMN2 formin 2
FOXD3 forkhead box D3
FOXO3 forkhead box O3
GABRB3 gamma-aminobutyric acid (GABA) A receptor, beta 3
GADL1 glutamate decarboxylase-like 1
GDF9 growth differentiation factor 9
GGA3 golgi-associated, gamma adaptin ear containing, ARF binding protein 3
GIN1 gypsy retrotransposon integrase 1
GJA1 gap junction protein, alpha 1, 43kDa
GJA3 gap junction protein, alpha 3, 46kDa
GLB1L3 galactosidase, beta 1-like 3
GOLIM4 golgi integral membrane protein 4
GPER1 G protein-coupled estrogen receptor 1
GPRIN2 G protein regulated inducer of neurite outgrowth 2
GRAP2 GRB2-related adaptor protein 2
GUCY2F guanylate cyclase 2F, retinal
GUSB glucuronidase, beta
HACL1 2-hydroxyacyl-CoA lyase 1
HAPLN1 hyaluronan and proteoglycan link protein 1
HAUS8 HAUS augmin-like complex, subunit 8
HEXIM1 hexamethylene bis-acetamide inducible 1
HLA-C major histocompatibility complex, class I, C
HOXA3 homeobox A3
HOXD4 homeobox D4
HPN hepsin
HS1BP3 HCLS1 binding protein 3
HSPG2 heparan sulfate proteoglycan 2
IDO2 indoleamine 2,3-dioxygenase 2
IGF1R insulin-like growth factor 1 receptor
IGSF22 immunoglobulin superfamily, member 22
IMPG1 interphotoreceptor matrix proteoglycan 1
INPPL1 inositol polyphosphate phosphatase-like 1
INTS1 integrator complex subunit 1
INTS5 integrator complex subunit 5
INTS8 integrator complex subunit 8
IPCEF1 interaction protein for cytohesin exchange factors 1
IQCJ IQ motif containing J
IQCJ-SCHIP1 IQCJ-SCHIP1 readthrough
IQSEC3 IQ motif and Sec7 domain 3
IRF8 interferon regulatory factor 8
IRS4 insulin receptor substrate 4
ISM2 isthmin 2
ITGA11 integrin, alpha 11
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
JADE1 jade family PHD finger 1
KAT6B K(lysine) acetyltransferase 6B
KDM2A lysine (K)-specific demethylase 2A
KDM4D lysine (K)-specific demethylase 4D
KIAA1671 KIAA1671
KIF13B kinesin family member 13B
KIF3C kinesin family member 3C
KIR2DL3 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3
KLHL38 kelch-like family member 38
KLHL6 kelch-like family member 6
L3MBTL4 l(3)mbt-like 4 (Drosophila)
LAD1 ladinin 1
LAMB1 laminin, beta 1
LAX1 lymphocyte transmembrane adaptor 1
LIPG lipase, endothelial
LIPN lipase, family member N
LNX2 ligand of numb-protein X 2
LOXL1 lysyl oxidase-like 1
LRFN2 leucine rich repeat and fibronectin type III domain containing 2
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1
LRIT1 leucine-rich repeat, immunoglobulin-like and transmembrane domains 1
LRP1 low density lipoprotein receptor-related protein 1
LRP8 low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
LRPPRC leucine-rich pentatricopeptide repeat containing
LRRC43 leucine rich repeat containing 43
LRRC4B leucine rich repeat containing 4B
LYST lysosomal trafficking regulator
MAB21L3 mab-21-like 3 (C. elegans)
MAGEC1 melanoma antigen family C1
MAMLD1 mastermind-like domain containing 1
MAPK8IP2 mitogen-activated protein kinase 8 interacting protein 2
MARCH7 membrane-associated ring finger (C3HC4) 7, E3 ubiquitin protein ligase
METRN meteorin, glial cell differentiation regulator
MKLN1 muskelin 1, intracellular mediator containing kelch motifs
MOB3B MOB kinase activator 3B
MRGPRX2 MAS-related GPR, member X2
MROH2A maestro heat-like repeat family member 2A
MRPL37 mitochondrial ribosomal protein L37
MUC16 mucin 16, cell surface associated
MUC4 mucin 4, cell surface associated
MUSK muscle, skeletal, receptor tyrosine kinase
MYH11 myosin, heavy chain 11, smooth muscle
MYO1E myosin IE
MYO1F myosin IF
NAMPT nicotinamide phosphoribosyltransferase
NAPG N-ethylmaleimide-sensitive factor attachment protein, gamma
NAV3 neuron navigator 3
NDUFV1 NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa
NEBL nebulette
NEK9 NIMA-related kinase 9
NET1 neuroepithelial cell transforming 1
NFYC nuclear transcription factor Y, gamma
NOD2 nucleotide-binding oligomerization domain containing 2
NOTCH4 notch 4
NPSR1 neuropeptide S receptor 1
NR1I3 nuclear receptor subfamily 1, group I, member 3
NRAP nebulin-related anchoring protein
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog
NRIP1 nuclear receptor interacting protein 1
NSD1 nuclear receptor binding SET domain protein 1
NSUN5P2 NOP2/Sun domain family, member 5 pseudogene 2
NSUN7 NOP2/Sun domain family, member 7
NUAK2 NUAK family, SNF1-like kinase, 2
NUTM2F NUT family member 2F
ODF3L2 outer dense fiber of sperm tails 3-like 2
OR13C2 olfactory receptor, family 13, subfamily C, member 2
OR1J1 olfactory receptor, family 1, subfamily J, member 1
OR1Q1 olfactory receptor, family 1, subfamily Q, member 1
OR4A13P olfactory receptor, family 4, subfamily A, member 13 pseudogene
OR52N4 olfactory receptor, family 52, subfamily N, member 4 (gene/pseudogene)
OR5AP2 olfactory receptor, family 5, subfamily AP, member 2
OR5B21 olfactory receptor, family 5, subfamily B, member 21
OR7E5P olfactory receptor, family 7, subfamily E, member 5 pseudogene
OR8J3 olfactory receptor, family 8, subfamily J, member 3
OR8U1 olfactory receptor, family 8, subfamily U, member 1
OVCH2 ovochymase 2 (gene/pseudogene)
PAAF1 proteasomal ATPase-associated factor 1
PABPC1 poly(A) binding protein, cytoplasmic 1
PARP4 poly (ADP-ribose) polymerase family, member 4
PCDH7 protocadherin 7
PCDHB5 protocadherin beta 5
PCDHGA8 protocadherin gamma subfamily A, 8
PCLO piccolo presynaptic cytomatrix protein
PCMTD2 protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2
PCSK5 proprotein convertase subtilisin/kexin type 5
PDE4DIP phosphodiesterase 4D interacting protein
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
PGS1 phosphatidylglycerophosphate synthase 1
PHGDH phosphoglycerate dehydrogenase
PIAS2 protein inhibitor of activated STAT, 2
PIEZO1 piezo-type mechanosensitive ion channel component 1
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PJA2 praja ring finger 2, E3 ubiquitin protein ligase
PKN1 protein kinase N1
PLCB4 phospholipase C, beta 4
PLEKHG4 pleckstrin homology domain containing, family G (with RhoGef domain) member 4
PLEKHH3 pleckstrin homology domain containing, family H (with MyTH4 domain) member 3
PLEKHM3 pleckstrin homology domain containing, family M, member 3
PLSCR5 phospholipid scramblase family, member 5
POM121L12 POM121 transmembrane nucleoporin-like 12
PON3 paraoxonase 3
PPM1A protein phosphatase, Mg2+/Mn2+ dependent, 1A
PRDM2 PR domain containing 2, with ZNF domain
PRDM7 PR domain containing 7
PRPF4 pre-mRNA processing factor 4
PRPF40B PRP40 pre-mRNA processing factor 40 homolog B (S. cerevisiae)
PRRC2A proline-rich coiled-coil 2A
PRTG protogenin
PSMC3IP PSMC3 interacting protein
PTGER4 prostaglandin E receptor 4 (subtype EP4)
PTGIS prostaglandin I2 (prostacyclin) synthase
PTPN4 protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)
PTPRB protein tyrosine phosphatase, receptor type, B
PTPRR protein tyrosine phosphatase, receptor type, R
RAB33B RAB33B, member RAS oncogene family
RAB39B RAB39B, member RAS oncogene family
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RANGRF RAN guanine nucleotide release factor
RB1CC1 RB1-inducible coiled-coil 1
RBM12B RNA binding motif protein 12B
RBPJL recombination signal binding protein for immunoglobulin kappa J region-like
RC3H2 ring finger and CCCH-type domains 2
RFPL3 ret finger protein-like 3
RFPL4A ret finger protein-like 4A
RFX1 regulatory factor X, 1 (influences HLA class II expression)
RFX4 regulatory factor X, 4 (influences HLA class II expression)
RFX7 regulatory factor X, 7
RFX8 RFX family member 8, lacking RFX DNA binding domain
RHOD ras homolog family member D
RNF213 ring finger protein 213
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
RPTN repetin
RSBN1L round spermatid basic protein 1-like
RTTN rotatin
SAFB2 scaffold attachment factor B2
SART3 squamous cell carcinoma antigen recognized by T cells 3
SEC13 SEC13 homolog (S. cerevisiae)
SEC16A SEC16 homolog A (S. cerevisiae)
SEC16B SEC16 homolog B (S. cerevisiae)
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SHANK1 SH3 and multiple ankyrin repeat domains 1
SHANK2 SH3 and multiple ankyrin repeat domains 2
SHISA6 shisa family member 6
SI sucrase-isomaltase (alpha-glucosidase)
SIPA1L2 signal-induced proliferation-associated 1 like 2
SLC25A41 solute carrier family 25, member 41
SLC26A5 solute carrier family 26 (anion exchanger), member 5
SLC26A7 solute carrier family 26 (anion exchanger), member 7
SLC26A9 solute carrier family 26 (anion exchanger), member 9
SLC39A12 solute carrier family 39 (zinc transporter), member 12
SLC39A4 solute carrier family 39 (zinc transporter), member 4
SLC5A1 solute carrier family 5 (sodium/glucose cotransporter), member 1
SLC6A16 solute carrier family 6, member 16
SLC6A5 solute carrier family 6 (neurotransmitter transporter), member 5
SLC7A9 solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9
SLCO1B3 solute carrier organic anion transporter family, member 1B3
SLCO1B7 solute carrier organic anion transporter family, member 1B7 (non-functional)
SMC4 structural maintenance of chromosomes 4
SMG5 SMG5 nonsense mediated mRNA decay factor
SNUPN snurportin 1
SORCS2 sortilin-related VPS10 domain containing receptor 2
SORCS3 sortilin-related VPS10 domain containing receptor 3
SPEF2 sperm flagellar 2
SPINT3 serine peptidase inhibitor, Kunitz type, 3
ST13 suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein)
ST8SIA5 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5
SVEP1 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
SYNE1 spectrin repeat containing, nuclear envelope 1
TACC2 transforming, acidic coiled-coil containing protein 2
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
TBC1D1 TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1
TBC1D10A TBC1 domain family, member 10A
TBCK TBC1 domain containing kinase
TBX5 T-box 5
TCERG1L transcription elongation regulator 1-like
TCHH trichohyalin
TENM4 teneurin transmembrane protein 4
TFDP1 transcription factor Dp-1
TFDP2 transcription factor Dp-2 (E2F dimerization partner 2)
TGFBI transforming growth factor, beta-induced, 68kDa
THSD7A thrombospondin, type I, domain containing 7A
TLN2 talin 2
TMC4 transmembrane channel-like 4
TMEM132D transmembrane protein 132D
TMEM215 transmembrane protein 215
TMEM219 transmembrane protein 219
TNFRSF6B tumor necrosis factor receptor superfamily, member 6b, decoy
TP53 tumor protein p53
TP53INP2 tumor protein p53 inducible nuclear protein 2
TPST1 tyrosylprotein sulfotransferase 1
TRAF7 TNF receptor-associated factor 7, E3 ubiquitin protein ligase
TRIM16L tripartite motif containing 16-like
TRIM4 tripartite motif containing 4
TRIM52 tripartite motif containing 52
TRIM55 tripartite motif containing 55
TRIM66 tripartite motif containing 66
TRIO trio Rho guanine nucleotide exchange factor
TRMT1L tRNA methyltransferase 1 homolog (S. cerevisiae)-like
TTC21A tetratricopeptide repeat domain 21A
TTLL10 tubulin tyrosine ligase-like family member 10
TTN titin
TUBG2 tubulin, gamma 2
TULP4 tubby like protein 4
TYW3 tRNA-yW synthesizing protein 3 homolog (S. cerevisiae)
UBE4B ubiquitination factor E4B
UBTD1 ubiquitin domain containing 1
UNC13B unc-13 homolog B (C. elegans)
UQCRC1 ubiquinol-cytochrome c reductase core protein I
USH2A Usher syndrome 2A (autosomal recessive, mild)
USP43 ubiquitin specific peptidase 43
USP54 ubiquitin specific peptidase 54
USP7 ubiquitin specific peptidase 7 (herpes virus-associated)
VAMP5 vesicle-associated membrane protein 5
VCX variable charge, X-linked
VCX2 variable charge, X-linked 2
VSNL1 visinin-like 1
VWA2 von Willebrand factor A domain containing 2
WDFY3 WD repeat and FYVE domain containing 3
WDR87 WD repeat domain 87
WNK4 WNK lysine deficient protein kinase 4
XRRA1 X-ray radiation resistance associated 1
ZCCHC16 zinc finger, CCHC domain containing 16
ZFHX3 zinc finger homeobox 3
ZFYVE26 zinc finger, FYVE domain containing 26
ZG16B zymogen granule protein 16B
ZNF106 zinc finger protein 106
ZNF148 zinc finger protein 148
ZNF2 zinc finger protein 2
ZNF253 zinc finger protein 253
ZNF263 zinc finger protein 263
ZNF266 zinc finger protein 266
ZNF407 zinc finger protein 407
ZNF492 zinc finger protein 492
ZNF610 zinc finger protein 610
ZNF770 zinc finger protein 770
ZNF786 zinc finger protein 786
ZNHIT6 zinc finger, HIT-type containing 6
ZNRF1 zinc and ring finger 1, E3 ubiquitin protein ligase
ZSCAN32 zinc finger and SCAN domain containing 32