| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | L-Eflornithine (monohydrochloride) perturbation in A549 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the L-Eflornithine (monohydrochloride)_A549 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.475964 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.114484 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.114328 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.111548 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.10566 |
| LDHA | lactate dehydrogenase A | 0.0986097 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0940154 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0896123 |
| UBC | ubiquitin C | 0.0807597 |
| MCL1 | myeloid cell leukemia 1 | 0.0788219 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0782423 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0782001 |
| POTEF | POTE ankyrin domain family, member F | 0.077649 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0774894 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0771991 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0744889 |
| SMAD3 | SMAD family member 3 | 0.0741299 |
| IGFBP4 | insulin-like growth factor binding protein 4 | 0.0696126 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.065684 |
| MSN | moesin | 0.0652941 |
| PKM | pyruvate kinase, muscle | 0.0652011 |
| SPAG9 | sperm associated antigen 9 | 0.0638825 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.062537 |
| FLNB | filamin B, beta | 0.0570622 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.053525 |
| VIM | vimentin | 0.0519441 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0501928 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0497478 |
| EFNA5 | ephrin-A5 | 0.0491586 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0489852 |
| CLTC | clathrin, heavy chain (Hc) | 0.048292 |
| ANXA2 | annexin A2 | 0.0482769 |
| MT1X | metallothionein 1X | 0.0470701 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0467308 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.0461107 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0449923 |
| VEGFA | vascular endothelial growth factor A | 0.04487 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0436773 |
| USP47 | ubiquitin specific peptidase 47 | 0.0428826 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0424674 |
| STC1 | stanniocalcin 1 | 0.042438 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0423563 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0420759 |
| CALU | calumenin | 0.0408868 |
| AXL | AXL receptor tyrosine kinase | 0.0407373 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0406792 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0404266 |
| DUSP5 | dual specificity phosphatase 5 | 0.0402487 |
| MYOF | myoferlin | 0.0399005 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0398419 |
| OPTN | optineurin | 0.0396389 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0394147 |
| USP34 | ubiquitin specific peptidase 34 | 0.0389461 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0387773 |
| CA12 | carbonic anhydrase XII | 0.0386123 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0376419 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0374186 |
| SFTPA2 | surfactant protein A2 | 0.0370335 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0366386 |
| ACTN4 | actinin, alpha 4 | 0.0365621 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0359137 |
| RPL3 | ribosomal protein L3 | 0.0358898 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0358803 |
| CD44 | CD44 molecule (Indian blood group) | 0.0352421 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0351502 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0346432 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0344731 |
| CMIP | c-Maf inducing protein | 0.0339136 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0338449 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0332741 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0325126 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0324196 |
| COPB1 | coatomer protein complex, subunit beta 1 | 0.0319581 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0317772 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0313581 |
| LOC112694756 | uncharaterized LOC112694756 | 0.031253 |
| PFKP | phosphofructokinase, platelet | 0.0312422 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0311604 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.030872 |
| RND3 | Rho family GTPase 3 | 0.0307774 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0305976 |
| CORO1C | coronin, actin binding protein, 1C | 0.0303158 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0302425 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0300741 |
| TCIM | transcriptional and immune response regulator | 0.0300229 |
| PYGL | phosphorylase, glycogen, liver | 0.0299811 |
| COPA | coatomer protein complex, subunit alpha | 0.0299784 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0299759 |
| VMP1 | vacuole membrane protein 1 | 0.0295707 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.0292753 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0291497 |
| ANO6 | anoctamin 6 | 0.0290792 |
| NDRG1 | N-myc downstream regulated 1 | 0.0289161 |
| APP | amyloid beta (A4) precursor protein | 0.0288781 |
| CANX | calnexin | 0.0284189 |
| PGK1 | phosphoglycerate kinase 1 | 0.0283909 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0283583 |
| OGA | O-GlcNAcase | 0.0282086 |
| YEATS2 | YEATS domain containing 2 | 0.0279404 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.027689 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0556128 |
| FTL | ferritin, light polypeptide | -0.054916 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.053435 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0465908 |
| PTMA | prothymosin, alpha | -0.0401522 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0395932 |
| BICC1 | BicC family RNA binding protein 1 | -0.0368154 |
| TMSB10 | thymosin beta 10 | -0.0345543 |
| RPS19 | ribosomal protein S19 | -0.0335729 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0335158 |
| ASPH | aspartate beta-hydroxylase | -0.0331216 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.03226 |
| EHBP1 | EH domain binding protein 1 | -0.0321407 |
| KYNU | kynureninase | -0.031894 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0313142 |
| GLIS3 | GLIS family zinc finger 3 | -0.0307574 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0301274 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0299948 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0295366 |
| RPLP0 | ribosomal protein, large, P0 | -0.0294795 |
| RPLP1 | ribosomal protein, large, P1 | -0.0289082 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0281384 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0267952 |
| RPS8 | ribosomal protein S8 | -0.0267925 |
| GABRB3 | gamma-aminobutyric acid (GABA) A receptor, beta 3 | -0.0265165 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | -0.0265149 |
| RPL35A | ribosomal protein L35a | -0.0263522 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0246006 |
| PDE10A | phosphodiesterase 10A | -0.0245277 |
| NRG1 | neuregulin 1 | -0.0242329 |
| S100A10 | S100 calcium binding protein A10 | -0.0240623 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0233391 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0232707 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0221929 |
| WWOX | WW domain containing oxidoreductase | -0.021908 |
| RPL38 | ribosomal protein L38 | -0.0212041 |
| ETV6 | ets variant 6 | -0.0210917 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0205167 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0192688 |
| ANTXR1 | anthrax toxin receptor 1 | -0.0190479 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0190156 |
| RPL19 | ribosomal protein L19 | -0.0180003 |
| USP3 | ubiquitin specific peptidase 3 | -0.0177967 |
| IGF1R | insulin-like growth factor 1 receptor | -0.01776 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0175607 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0174254 |
| TKT | transketolase | -0.0173778 |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) | -0.0167873 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0167196 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | -0.016692 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.016639 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -0.0166304 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.016592 |
| RPL37A | ribosomal protein L37a | -0.0164315 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0163727 |
| AUTS2 | autism susceptibility candidate 2 | -0.0163077 |
| RPL13A | ribosomal protein L13a | -0.0161792 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 | -0.0160688 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.016054 |
| SMAD2 | SMAD family member 2 | -0.0160525 |
| PDE7B | phosphodiesterase 7B | -0.0160168 |
| RPL12 | ribosomal protein L12 | -0.015997 |
| PBX1 | pre-B-cell leukemia homeobox 1 | -0.0159649 |
| RPS24 | ribosomal protein S24 | -0.0158583 |
| RPS6 | ribosomal protein S6 | -0.0156582 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0156465 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | -0.0155803 |
| TFRC | transferrin receptor | -0.0155647 |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain | -0.0155598 |
| UBB | ubiquitin B | -0.0154301 |
| PTK2 | protein tyrosine kinase 2 | -0.0153703 |
| CDC42SE2 | CDC42 small effector 2 | -0.0153341 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | -0.0151325 |
| MT2A | metallothionein 2A | -0.0150784 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | -0.0150488 |
| AOPEP | aminopeptidase O (putative) | -0.0146521 |
| NCKAP5 | NCK-associated protein 5 | -0.0145532 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0142637 |
| EVA1C | eva-1 homolog C (C. elegans) | -0.0141998 |
| RIOK3 | RIO kinase 3 | -0.0140578 |
| MIPOL1 | mirror-image polydactyly 1 | -0.0140491 |
| ANXA1 | annexin A1 | -0.0139957 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0139761 |
| RAI14 | retinoic acid induced 14 | -0.0139384 |
| CUX1 | cut-like homeobox 1 | -0.0137843 |
| NME2 | NME/NM23 nucleoside diphosphate kinase 2 | -0.0137188 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0137144 |
| NRP1 | neuropilin 1 | -0.013681 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0135667 |
| LMO7 | LIM domain 7 | -0.0135633 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | -0.0135329 |
| USP15 | ubiquitin specific peptidase 15 | -0.0135244 |
| NCOA1 | nuclear receptor coactivator 1 | -0.0134449 |
| RPL28 | ribosomal protein L28 | -0.0134216 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.0133935 |
| GPRIN3 | GPRIN family member 3 | -0.0133397 |
| MCU | mitochondrial calcium uniporter | -0.0132995 |
| NASP | nuclear autoantigenic sperm protein (histone-binding) | -0.0132827 |
| SRSF7 | serine/arginine-rich splicing factor 7 | -0.0132012 |
| NFIB | nuclear factor I/B | -0.0131129 |
