| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | L-Eflornithine (monohydrochloride) perturbation in BT-474 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the L-Eflornithine (monohydrochloride)_BT-474 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VMP1 | vacuole membrane protein 1 | 0.154949 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.148657 |
| ASPH | aspartate beta-hydroxylase | 0.131541 |
| NCOA3 | nuclear receptor coactivator 3 | 0.107367 |
| CATSPERB | catsper channel auxiliary subunit beta | 0.096101 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0940485 |
| CDK12 | cyclin-dependent kinase 12 | 0.0920365 |
| ANKRD36C | ankyrin repeat domain 36C | 0.0905441 |
| TRPS1 | trichorhinophalangeal syndrome I | 0.0851638 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0800141 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0704217 |
| SMYD3 | SET and MYND domain containing 3 | 0.0695877 |
| CLTC | clathrin, heavy chain (Hc) | 0.0604874 |
| DNAH14 | dynein, axonemal, heavy chain 14 | 0.0547293 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0526015 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0493863 |
| APP | amyloid beta (A4) precursor protein | 0.0489001 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0488715 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0475041 |
| NTN4 | netrin 4 | 0.0474979 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | 0.0462185 |
| TNIK | TRAF2 and NCK interacting kinase | 0.0459001 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.045876 |
| OSMR | oncostatin M receptor | 0.045556 |
| VAV3 | vav 3 guanine nucleotide exchange factor | 0.045304 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0433416 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0430111 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | 0.0429285 |
| STRN3 | striatin, calmodulin binding protein 3 | 0.0418157 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0409967 |
| MYO5B | myosin VB | 0.0409714 |
| TC2N | tandem C2 domains, nuclear | 0.0406918 |
| NCOA7 | nuclear receptor coactivator 7 | 0.0404104 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0402152 |
| SRCIN1 | SRC kinase signaling inhibitor 1 | 0.0386997 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0382778 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0371078 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | 0.0358805 |
| KIAA1217 | KIAA1217 | 0.0356317 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0350636 |
| DST | dystonin | 0.0345197 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0345139 |
| DUSP16 | dual specificity phosphatase 16 | 0.0343473 |
| MYO1D | myosin ID | 0.0326689 |
| AHR | aryl hydrocarbon receptor | 0.0320935 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0320426 |
| SETX | senataxin | 0.0317437 |
| EFNA5 | ephrin-A5 | 0.0310984 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0308684 |
| SHROOM3 | shroom family member 3 | 0.0308466 |
| SGMS1 | sphingomyelin synthase 1 | 0.030642 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0299921 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0297741 |
| GLCCI1 | glucocorticoid induced 1 | 0.0297147 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0297054 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | 0.0287637 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 0.0283414 |
| CEP250 | centrosomal protein 250kDa | 0.0281868 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.0280288 |
| PSMD3 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 | 0.0279672 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0279087 |
| PRRC2B | proline-rich coiled-coil 2B | 0.0275079 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.027345 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0272662 |
| PATJ | PATJ crumbs cell polarity complex component | 0.0271851 |
| TANC1 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 | 0.0267744 |
| ACACA | acetyl-CoA carboxylase alpha | 0.0267625 |
| TNFAIP8 | tumor necrosis factor, alpha-induced protein 8 | 0.0263085 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0259797 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.025773 |
| RAB22A | RAB22A, member RAS oncogene family | 0.0257365 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0256406 |
| PTK2 | protein tyrosine kinase 2 | 0.0253798 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0253478 |
| ENAH | enabled homolog (Drosophila) | 0.0252606 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.024935 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0247049 |
| WASL | Wiskott-Aldrich syndrome-like | 0.0243331 |
| PAWR | PRKC, apoptosis, WT1, regulator | 0.0242933 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0242463 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0240887 |
| DENND1A | DENN/MADD domain containing 1A | 0.0240674 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0233494 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0233156 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | 0.0232564 |
| SYTL2 | synaptotagmin-like 2 | 0.0231676 |
| ITGB6 | integrin, beta 6 | 0.0230553 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0227946 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0227809 |
| FAM168A | family with sequence similarity 168, member A | 0.0227622 |
| FOXP1 | forkhead box P1 | 0.022505 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0224922 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0223858 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0223605 |
| UBC | ubiquitin C | 0.0222826 |
| TAB3 | TGF-beta activated kinase 1/MAP3K7 binding protein 3 | 0.0222773 |
| TMC5 | transmembrane channel-like 5 | 0.0221464 |
| SEPTIN9 | septin 9 | 0.0220891 |
| MSI2 | musashi RNA-binding protein 2 | 0.0220444 |
| TRAPPC9 | trafficking protein particle complex 9 | 0.0220206 |
| Symbol | Name | Standardized Value |
|---|---|---|
| RPL23 | ribosomal protein L23 | -0.162944 |
| PTMA | prothymosin, alpha | -0.122249 |
| RPL19 | ribosomal protein L19 | -0.116868 |
| NDRG1 | N-myc downstream regulated 1 | -0.0974717 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.097123 |
| ACSS2 | acyl-CoA synthetase short-chain family member 2 | -0.0727721 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0722799 |
| LASP1 | LIM and SH3 protein 1 | -0.0718998 |
| RPL35A | ribosomal protein L35a | -0.0610316 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0511806 |
| RPS3 | ribosomal protein S3 | -0.0487604 |
| RPL37A | ribosomal protein L37a | -0.0450407 |
| DSTN | destrin (actin depolymerizing factor) | -0.0449993 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0443341 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.0437311 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming | -0.0431782 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0423758 |
| RPS6 | ribosomal protein S6 | -0.0407194 |
| RPLP1 | ribosomal protein, large, P1 | -0.0385696 |
| TMSB10 | thymosin beta 10 | -0.0377277 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0366512 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0365483 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0359892 |
| ACTG1 | actin gamma 1 | -0.0357751 |
| RPL12 | ribosomal protein L12 | -0.0356012 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0353346 |
| GRB7 | growth factor receptor-bound protein 7 | -0.0348315 |
| MLLT6 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6 | -0.0335011 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0329764 |
| B2M | beta-2-microglobulin | -0.0323734 |
| ERBB2 | erb-b2 receptor tyrosine kinase 2 | -0.0320696 |
| KRT19 | keratin 19, type I | -0.0313635 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0305001 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0303408 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0303302 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0302997 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0300551 |
| CCND1 | cyclin D1 | -0.0295177 |
| FTL | ferritin, light polypeptide | -0.0289848 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0286406 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0285713 |
| RPS8 | ribosomal protein S8 | -0.0278169 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0275132 |
| RPL8 | ribosomal protein L8 | -0.0271639 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.027045 |
| RPS19 | ribosomal protein S19 | -0.0268171 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0258797 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | -0.0254265 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0251408 |
| GNAS | GNAS complex locus | -0.0250841 |
| RPL11 | ribosomal protein L11 | -0.0244134 |
| RPL34 | ribosomal protein L34 | -0.0241719 |
| LMNA | lamin A/C | -0.0238213 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0234846 |
| TPM4 | tropomyosin 4 | -0.0234609 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.023318 |
| GOLGA4 | golgin A4 | -0.0232239 |
| FADS2 | fatty acid desaturase 2 | -0.0229842 |
| TMEM165 | transmembrane protein 165 | -0.0228593 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.0225624 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0225549 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0215827 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0214489 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0213445 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0213085 |
| HLA-B | major histocompatibility complex, class I, B | -0.0209563 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0207338 |
| ESRP1 | epithelial splicing regulatory protein 1 | -0.0206822 |
| RPS12 | ribosomal protein S12 | -0.0206321 |
| PKM | pyruvate kinase, muscle | -0.0204649 |
| GGNBP2 | gametogenetin binding protein 2 | -0.0203772 |
| RPS27A | ribosomal protein S27a | -0.0201067 |
| POTEF | POTE ankyrin domain family, member F | -0.0198549 |
| SRP54 | signal recognition particle 54kDa | -0.0197909 |
| TMSB4X | thymosin beta 4, X-linked | -0.0193829 |
| FDPS | farnesyl diphosphate synthase | -0.0193686 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | -0.0192957 |
| KRT7 | keratin 7, type II | -0.0192401 |
| TPD52 | tumor protein D52 | -0.019051 |
| VEGFA | vascular endothelial growth factor A | -0.0190357 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0190173 |
| ADM | adrenomedullin | -0.0188853 |
| BCAS1 | breast carcinoma amplified sequence 1 | -0.0188436 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0188376 |
| RPL10A | ribosomal protein L10a | -0.018805 |
| RPL35 | ribosomal protein L35 | -0.0187979 |
| RPL31 | ribosomal protein L31 | -0.0187634 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.0185526 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0178887 |
| RPL5 | ribosomal protein L5 | -0.0177703 |
| RBM47 | RNA binding motif protein 47 | -0.0177251 |
| RPS24 | ribosomal protein S24 | -0.0176437 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0176076 |
| RPL37 | ribosomal protein L37 | -0.0175058 |
| TPCN1 | two pore segment channel 1 | -0.0174022 |
| INSIG1 | insulin induced gene 1 | -0.017377 |
| IDI1 | isopentenyl-diphosphate delta isomerase 1 | -0.017285 |
| RPS29 | ribosomal protein S29 | -0.017236 |
| RPL7A | ribosomal protein L7a | -0.0171228 |
| TUBA1B | tubulin, alpha 1b | -0.0171222 |
