| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | L-Eflornithine (monohydrochloride) perturbation in CHP-212 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the L-Eflornithine (monohydrochloride)_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | 0.400171 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.204715 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.159379 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.143864 |
| PTMA | prothymosin, alpha | 0.13827 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0812262 |
| PLAT | plasminogen activator, tissue | 0.0758775 |
| VIM | vimentin | 0.0723641 |
| RPL23 | ribosomal protein L23 | 0.06851 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0672055 |
| MEIS2 | Meis homeobox 2 | 0.0630199 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0606587 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0592902 |
| TLE4 | transducin-like enhancer of split 4 | 0.0522677 |
| RPS6 | ribosomal protein S6 | 0.0511964 |
| MAP1B | microtubule-associated protein 1B | 0.0506929 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0483077 |
| FMN1 | formin 1 | 0.0474417 |
| PGK1 | phosphoglycerate kinase 1 | 0.0472008 |
| RPL12 | ribosomal protein L12 | 0.0464692 |
| DST | dystonin | 0.0461568 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0457911 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0453163 |
| HMGB2 | high mobility group box 2 | 0.044728 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0446691 |
| VEGFA | vascular endothelial growth factor A | 0.044405 |
| DPH6 | diphthamine biosynthesis 6 | 0.0439417 |
| PKM | pyruvate kinase, muscle | 0.0428477 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0427034 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0425057 |
| GOLGA4 | golgin A4 | 0.0422795 |
| RPS3 | ribosomal protein S3 | 0.0419873 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0417866 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0415008 |
| APP | amyloid beta (A4) precursor protein | 0.041235 |
| RPL19 | ribosomal protein L19 | 0.0408223 |
| CENPF | centromere protein F, 350/400kDa | 0.0407144 |
| SET | SET nuclear proto-oncogene | 0.0404266 |
| RPLP1 | ribosomal protein, large, P1 | 0.0402556 |
| MEF2A | myocyte enhancer factor 2A | 0.0395008 |
| MYCN | v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog | 0.0394439 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0392346 |
| SYT1 | synaptotagmin I | 0.0391936 |
| USP34 | ubiquitin specific peptidase 34 | 0.039174 |
| WDR45B | WD repeat domain 45B | 0.0390821 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0388203 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0387938 |
| B2M | beta-2-microglobulin | 0.0372119 |
| UBC | ubiquitin C | 0.0369064 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0364552 |
| RPL37A | ribosomal protein L37a | 0.0356107 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | 0.0355984 |
| ACTG1 | actin gamma 1 | 0.0352446 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0350176 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0346483 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0343434 |
| TPR | translocated promoter region, nuclear basket protein | 0.0342579 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.0342157 |
| RPL35A | ribosomal protein L35a | 0.0337093 |
| SEPTIN9 | septin 9 | 0.0333941 |
| H3-3B | H3.3 histone B | 0.0331093 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | 0.032823 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.032182 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0321758 |
| TOP1 | topoisomerase (DNA) I | 0.0319591 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0314626 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0313712 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0310527 |
| RPS27 | ribosomal protein S27 | 0.0307069 |
| MYO6 | myosin VI | 0.0306405 |
| TPST1 | tyrosylprotein sulfotransferase 1 | 0.0305809 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0304628 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.0304619 |
| RSL1D1 | ribosomal L1 domain containing 1 | 0.0304277 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0304224 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0303705 |
| JMJD1C | jumonji domain containing 1C | 0.0302654 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0302076 |
| ANXA2 | annexin A2 | 0.0301931 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0300252 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | 0.029999 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | 0.0298014 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0296984 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0294251 |
| RPL38 | ribosomal protein L38 | 0.0292901 |
| SLITRK6 | SLIT and NTRK-like family, member 6 | 0.0292897 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0290986 |
| AHR | aryl hydrocarbon receptor | 0.0290168 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0289357 |
| RSF1 | remodeling and spacing factor 1 | 0.0288911 |
| GNAS | GNAS complex locus | 0.0285025 |
| RPLP0 | ribosomal protein, large, P0 | 0.0284998 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0283492 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0281866 |
| SENP6 | SUMO1/sentrin specific peptidase 6 | 0.0279082 |
| IGF2 | insulin-like growth factor 2 | 0.0278498 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0277079 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0276972 |
| VMP1 | vacuole membrane protein 1 | 0.027617 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.0275153 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LSAMP | limbic system-associated membrane protein | -0.0693285 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.054771 |
| TRIB2 | tribbles pseudokinase 2 | -0.041164 |
| MAPK10 | mitogen-activated protein kinase 10 | -0.0276281 |
| LARGE1 | LARGE xylosyl- and glucuronyltransferase 1 | -0.0246376 |
| GSE1 | Gse1 coiled-coil protein | -0.0246076 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0237052 |
| RPTOR | regulatory associated protein of MTOR, complex 1 | -0.0228025 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0224202 |
| ST6GALNAC3 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 | -0.0209286 |
| MSI2 | musashi RNA-binding protein 2 | -0.0197063 |
| ANTXR1 | anthrax toxin receptor 1 | -0.0194528 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | -0.0192649 |
| DACH2 | dachshund family transcription factor 2 | -0.0191445 |
| ANK2 | ankyrin 2, neuronal | -0.0191058 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.018795 |
| KDM4C | lysine (K)-specific demethylase 4C | -0.0185215 |
| RNF150 | ring finger protein 150 | -0.0181778 |
| DNAH14 | dynein, axonemal, heavy chain 14 | -0.0180778 |
| ATF7IP2 | activating transcription factor 7 interacting protein 2 | -0.0174598 |
| COL18A1 | collagen, type XVIII, alpha 1 | -0.0171407 |
| LRFN5 | leucine rich repeat and fibronectin type III domain containing 5 | -0.0165526 |
| ZNF804A | zinc finger protein 804A | -0.0163333 |
| SMYD3 | SET and MYND domain containing 3 | -0.0159996 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0159727 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | -0.0158111 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0157873 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | -0.0157316 |
| KDM3B | lysine (K)-specific demethylase 3B | -0.0152356 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0148146 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0147198 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | -0.0147062 |
| EGFR | epidermal growth factor receptor | -0.01457 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0144587 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0144544 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0143452 |
| PBX1 | pre-B-cell leukemia homeobox 1 | -0.0142231 |
| FREM1 | FRAS1 related extracellular matrix 1 | -0.0141609 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0140778 |
| COL4A6 | collagen, type IV, alpha 6 | -0.0140233 |
| UNC5C | unc-5 homolog C (C. elegans) | -0.0139904 |
| NBEA | neurobeachin | -0.0139532 |
| FGF14 | fibroblast growth factor 14 | -0.0138451 |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 | -0.0135461 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | -0.0129082 |
| CBR4 | carbonyl reductase 4 | -0.012839 |
| FILIP1L | filamin A interacting protein 1-like | -0.0128198 |
| KDM4B | lysine (K)-specific demethylase 4B | -0.0127784 |
| AEBP2 | AE binding protein 2 | -0.0126594 |
| NETO1 | neuropilin (NRP) and tolloid (TLL)-like 1 | -0.0126305 |
| CLINT1 | clathrin interactor 1 | -0.0126291 |
| AFF3 | AF4/FMR2 family, member 3 | -0.0126211 |
| DIAPH2 | diaphanous-related formin 2 | -0.0125198 |
| NREP | neuronal regeneration related protein | -0.0123649 |
| GPR75-ASB3 | GPR75-ASB3 readthrough | -0.0122652 |
| VAV2 | vav 2 guanine nucleotide exchange factor | -0.0122437 |
| PKD1 | polycystic kidney disease 1 (autosomal dominant) | -0.0121371 |
| BLTP1 | bridge-like lipid transfer protein family member 1 | -0.0121188 |
| ZFYVE28 | zinc finger, FYVE domain containing 28 | -0.0120364 |
| SMAD6 | SMAD family member 6 | -0.0119561 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.0119184 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0117939 |
| PHF21A | PHD finger protein 21A | -0.0117565 |
| C1ORF21 | chromosome 1 open reading frame 21 | -0.0115824 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0115608 |
| DISC1 | disrupted in schizophrenia 1 | -0.0115535 |
| TPM1 | tropomyosin 1 (alpha) | -0.0114739 |
| TRIM24 | tripartite motif containing 24 | -0.0114467 |
| FOXK1 | forkhead box K1 | -0.0113557 |
| HIBADH | 3-hydroxyisobutyrate dehydrogenase | -0.0112251 |
| CCDC88A | coiled-coil domain containing 88A | -0.0111464 |
| UHRF2 | ubiquitin-like with PHD and ring finger domains 2, E3 ubiquitin protein ligase | -0.0111052 |
| HOMER1 | homer scaffolding protein 1 | -0.011063 |
| PTPRS | protein tyrosine phosphatase, receptor type, S | -0.0110491 |
| IFRD1 | interferon-related developmental regulator 1 | -0.0110317 |
| PRKCE | protein kinase C, epsilon | -0.0109841 |
| PDZRN3 | PDZ domain containing ring finger 3 | -0.0108934 |
| SLC25A26 | solute carrier family 25 (S-adenosylmethionine carrier), member 26 | -0.0108413 |
| SRSF7 | serine/arginine-rich splicing factor 7 | -0.0108068 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0107758 |
| NFIB | nuclear factor I/B | -0.0107679 |
| ARF1 | ADP-ribosylation factor 1 | -0.0107468 |
| UBAP1 | ubiquitin associated protein 1 | -0.0107353 |
| JAM3 | junctional adhesion molecule 3 | -0.0107261 |
| EFNA5 | ephrin-A5 | -0.0106968 |
| GTF2E2 | general transcription factor IIE, polypeptide 2, beta 34kDa | -0.0106937 |
| FAM53C | family with sequence similarity 53, member C | -0.0106072 |
| ACACA | acetyl-CoA carboxylase alpha | -0.0105529 |
| IFT140 | intraflagellar transport 140 | -0.0105149 |
| ITGB3BP | integrin beta 3 binding protein (beta3-endonexin) | -0.0104978 |
| TIAM2 | T-cell lymphoma invasion and metastasis 2 | -0.0104863 |
| FBXL4 | F-box and leucine-rich repeat protein 4 | -0.010454 |
| AIG1 | androgen-induced 1 | -0.0104134 |
| KANSL1L | KAT8 regulatory NSL complex subunit 1-like | -0.0104094 |
| NOTCH1 | notch 1 | -0.0103432 |
| KIAA1217 | KIAA1217 | -0.0103268 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.010267 |
| PCDH11Y | protocadherin 11 Y-linked | -0.010266 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | -0.0102068 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | -0.0102036 |
