| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | L-Eflornithine (monohydrochloride) perturbation in H4 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the L-Eflornithine (monohydrochloride)_H4 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COL6A3 | collagen, type VI, alpha 3 | 0.184645 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.184439 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.170952 |
| FTL | ferritin, light polypeptide | 0.166448 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.128951 |
| VEGFA | vascular endothelial growth factor A | 0.113861 |
| INHBA | inhibin, beta A | 0.109176 |
| CANX | calnexin | 0.107377 |
| LDHA | lactate dehydrogenase A | 0.101899 |
| GOLGB1 | golgin B1 | 0.07808 |
| EGFR | epidermal growth factor receptor | 0.0777969 |
| CALR | calreticulin | 0.0776171 |
| CADM1 | cell adhesion molecule 1 | 0.0725786 |
| ZNF395 | zinc finger protein 395 | 0.067827 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0666783 |
| MKI67 | marker of proliferation Ki-67 | 0.0655055 |
| SBF2 | SET binding factor 2 | 0.0620651 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.0608359 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0604179 |
| MT2A | metallothionein 2A | 0.0588625 |
| FNIP1 | folliculin interacting protein 1 | 0.0544053 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | 0.0540262 |
| PGK1 | phosphoglycerate kinase 1 | 0.0535677 |
| MYOF | myoferlin | 0.0520492 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0514615 |
| MT1X | metallothionein 1X | 0.0504064 |
| LMAN1 | lectin, mannose-binding, 1 | 0.0503812 |
| CENPF | centromere protein F, 350/400kDa | 0.0487498 |
| MSN | moesin | 0.0486201 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0472434 |
| TUBB | tubulin, beta class I | 0.0468399 |
| SPAG9 | sperm associated antigen 9 | 0.0457397 |
| SERPINH1 | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) | 0.0455454 |
| FNDC3B | fibronectin type III domain containing 3B | 0.045332 |
| CALD1 | caldesmon 1 | 0.0451245 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.04454 |
| TPM4 | tropomyosin 4 | 0.0441316 |
| MON2 | MON2 homolog (S. cerevisiae) | 0.0438838 |
| TPX2 | TPX2, microtubule-associated | 0.0438668 |
| COPA | coatomer protein complex, subunit alpha | 0.0435335 |
| EGR1 | early growth response 1 | 0.0429236 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0424258 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.042072 |
| MORF4L2 | mortality factor 4 like 2 | 0.0419899 |
| ZNF451 | zinc finger protein 451 | 0.0403525 |
| GOLGA4 | golgin A4 | 0.0401692 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0397736 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0394553 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0391192 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0386345 |
| VCL | vinculin | 0.0380402 |
| ZNF146 | zinc finger protein 146 | 0.0367662 |
| TPI1 | triosephosphate isomerase 1 | 0.0367195 |
| WDR45B | WD repeat domain 45B | 0.0363101 |
| SLC3A2 | solute carrier family 3 (amino acid transporter heavy chain), member 2 | 0.03617 |
| MAP1B | microtubule-associated protein 1B | 0.0359966 |
| NBEAL1 | neurobeachin-like 1 | 0.0354729 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0352143 |
| CDK19 | cyclin-dependent kinase 19 | 0.0350748 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0350007 |
| SRP54 | signal recognition particle 54kDa | 0.0348518 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0347816 |
| ATM | ATM serine/threonine kinase | 0.0347297 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0346751 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0346101 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0341226 |
| RARS1 | arginyl-tRNA synthetase 1 | 0.0337483 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0334087 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0332272 |
| HDLBP | high density lipoprotein binding protein | 0.0331269 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.032652 |
| SFTPA2 | surfactant protein A2 | 0.0325148 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0324641 |
| NAV2 | neuron navigator 2 | 0.0322106 |
| BOD1L1 | biorientation of chromosomes in cell division 1-like 1 | 0.0320916 |
| B2M | beta-2-microglobulin | 0.0317868 |
| WASF2 | WAS protein family, member 2 | 0.0316432 |
| TMEM39A | transmembrane protein 39A | 0.0315138 |
| RPL3 | ribosomal protein L3 | 0.0312768 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0312405 |
| VMP1 | vacuole membrane protein 1 | 0.0310982 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0306845 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.030573 |
| GCC2 | GRIP and coiled-coil domain containing 2 | 0.0305459 |
| GPR173 | G protein-coupled receptor 173 | 0.0301248 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0299363 |
| SCFD2 | sec1 family domain containing 2 | 0.0290365 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0289874 |
| AP1G1 | adaptor-related protein complex 1, gamma 1 subunit | 0.0285215 |
| CUL4B | cullin 4B | 0.028428 |
| SMC5 | structural maintenance of chromosomes 5 | 0.0283248 |
| ANLN | anillin, actin binding protein | 0.0282306 |
| ERBIN | erbb2 interacting protein | 0.0281408 |
| TMEM41B | transmembrane protein 41B | 0.0280468 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.027984 |
| USP47 | ubiquitin specific peptidase 47 | 0.0278934 |
| RAI1 | retinoic acid induced 1 | 0.0275993 |
| RLIM | ring finger protein, LIM domain interacting | 0.0275971 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0272713 |
| MMP12 | matrix metallopeptidase 12 | 0.0272383 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.174884 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.113472 |
| RPS27A | ribosomal protein S27a | -0.10282 |
| GLIS3 | GLIS family zinc finger 3 | -0.0898123 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0792172 |
| AHNAK | AHNAK nucleoprotein | -0.0773098 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0772771 |
| ASPH | aspartate beta-hydroxylase | -0.0742713 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0631287 |
| UBC | ubiquitin C | -0.061836 |
| TXNIP | thioredoxin interacting protein | -0.0556399 |
| DTNA | dystrobrevin, alpha | -0.0541426 |
| PCBP2 | poly(rC) binding protein 2 | -0.052281 |
| TENM3 | teneurin transmembrane protein 3 | -0.0513671 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0509096 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.04952 |
| AUTS2 | autism susceptibility candidate 2 | -0.0462998 |
| PTK2 | protein tyrosine kinase 2 | -0.0454775 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0441874 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0441614 |
| JUN | jun proto-oncogene | -0.0436738 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0409221 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0406166 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0402118 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0384997 |
| CD44 | CD44 molecule (Indian blood group) | -0.038247 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0382373 |
| LOC112694756 | uncharaterized LOC112694756 | -0.03742 |
| PRDX1 | peroxiredoxin 1 | -0.0351015 |
| CALN1 | calneuron 1 | -0.0349351 |
| PLEC | plectin | -0.034728 |
| SFPQ | splicing factor proline/glutamine-rich | -0.0342848 |
| RPL37A | ribosomal protein L37a | -0.0326962 |
| TMSB10 | thymosin beta 10 | -0.0323592 |
| TXNRD1 | thioredoxin reductase 1 | -0.0321467 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | -0.0318076 |
| CREB5 | cAMP responsive element binding protein 5 | -0.0312408 |
| ATXN10 | ataxin 10 | -0.0309762 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0308325 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0306538 |
| HIBADH | 3-hydroxyisobutyrate dehydrogenase | -0.030505 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0304686 |
| RPL23 | ribosomal protein L23 | -0.0301655 |
| TAOK1 | TAO kinase 1 | -0.0298449 |
| MAP4 | microtubule-associated protein 4 | -0.0296976 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | -0.0295692 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0294597 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | -0.0292636 |
| PCNX1 | pecanex 1 | -0.0290868 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0286036 |
| SQSTM1 | sequestosome 1 | -0.0285307 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0283496 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0278819 |
| PHF14 | PHD finger protein 14 | -0.0278636 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | -0.0276837 |
| IL6ST | interleukin 6 signal transducer | -0.0270207 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0269513 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0267156 |
| RPS17 | ribosomal protein S17 | -0.0266973 |
| NIBAN2 | niban apoptosis regulator 2 | -0.026401 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0262397 |
| ZNF207 | zinc finger protein 207 | -0.0260844 |
| SMYD3 | SET and MYND domain containing 3 | -0.0260023 |
| SRPK2 | SRSF protein kinase 2 | -0.0256321 |
| CUX1 | cut-like homeobox 1 | -0.0255571 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.025436 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0251787 |
| LNPEP | leucyl/cystinyl aminopeptidase | -0.024933 |
| UBA2 | ubiquitin-like modifier activating enzyme 2 | -0.0247232 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0245732 |
| HLA-B | major histocompatibility complex, class I, B | -0.0242647 |
| ZNF609 | zinc finger protein 609 | -0.0240724 |
| PSMD11 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 | -0.0237667 |
| XPO1 | exportin 1 | -0.0234766 |
| FLNA | filamin A, alpha | -0.0233055 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0232519 |
| OR51B5 | olfactory receptor, family 51, subfamily B, member 5 | -0.0232331 |
| XKR6 | XK, Kell blood group complex subunit-related family, member 6 | -0.0230818 |
| HOOK2 | hook microtubule-tethering protein 2 | -0.0230132 |
| MCL1 | myeloid cell leukemia 1 | -0.0229975 |
| CHRM3 | cholinergic receptor, muscarinic 3 | -0.0229956 |
| NUMB | numb homolog (Drosophila) | -0.0229873 |
| USP34 | ubiquitin specific peptidase 34 | -0.0228616 |
| MTPN | myotrophin | -0.0228445 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0228062 |
| HLCS | holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase) | -0.0226647 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0226327 |
| APP | amyloid beta (A4) precursor protein | -0.0224793 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0224622 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | -0.0223834 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.0222538 |
| EHBP1L1 | EH domain binding protein 1-like 1 | -0.0222405 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0221035 |
| WWOX | WW domain containing oxidoreductase | -0.0220116 |
| WLS | wntless Wnt ligand secretion mediator | -0.0217922 |
| TUSC3 | tumor suppressor candidate 3 | -0.0217436 |
| FMNL2 | formin-like 2 | -0.0216865 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0216576 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0216309 |
| COMMD10 | COMM domain containing 10 | -0.0211968 |
