| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | L-Eflornithine (monohydrochloride) perturbation in HCT15 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the L-Eflornithine (monohydrochloride)_HCT15 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ENO1 | enolase 1, (alpha) | 0.167628 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.151391 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.144808 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.124414 |
| AHNAK | AHNAK nucleoprotein | 0.123412 |
| LDHA | lactate dehydrogenase A | 0.12215 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.119893 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.114748 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.113836 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0991639 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0890653 |
| NDRG1 | N-myc downstream regulated 1 | 0.0883076 |
| EZR | ezrin | 0.0877731 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0859769 |
| PTMA | prothymosin, alpha | 0.0819606 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0803853 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0796052 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0741572 |
| ASPH | aspartate beta-hydroxylase | 0.0735627 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0724276 |
| VEGFA | vascular endothelial growth factor A | 0.0706016 |
| MKI67 | marker of proliferation Ki-67 | 0.0700513 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0699584 |
| TBC1D22A | TBC1 domain family, member 22A | 0.068039 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0679754 |
| UBC | ubiquitin C | 0.0676761 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0657596 |
| ZNF638 | zinc finger protein 638 | 0.0651427 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0648871 |
| RPL3 | ribosomal protein L3 | 0.0645691 |
| DSPP | dentin sialophosphoprotein | 0.0641721 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0631368 |
| FAT1 | FAT atypical cadherin 1 | 0.0626054 |
| CANX | calnexin | 0.0609529 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.059906 |
| MCL1 | myeloid cell leukemia 1 | 0.0590085 |
| MYOF | myoferlin | 0.058655 |
| PGK1 | phosphoglycerate kinase 1 | 0.0584707 |
| PKM | pyruvate kinase, muscle | 0.0564986 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0557119 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0551323 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0546257 |
| HMGB2 | high mobility group box 2 | 0.0528153 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0515148 |
| TPM3 | tropomyosin 3 | 0.0513704 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0505138 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0492028 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0488523 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0484806 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.046931 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0466925 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0464447 |
| PCM1 | pericentriolar material 1 | 0.0462496 |
| VMP1 | vacuole membrane protein 1 | 0.0459345 |
| TMF1 | TATA element modulatory factor 1 | 0.0456157 |
| YEATS2 | YEATS domain containing 2 | 0.044622 |
| HELZ | helicase with zinc finger | 0.0445322 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0437265 |
| GOLGA4 | golgin A4 | 0.0426993 |
| POTEF | POTE ankyrin domain family, member F | 0.0424973 |
| CTBP2 | C-terminal binding protein 2 | 0.0423423 |
| CENPF | centromere protein F, 350/400kDa | 0.042299 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.041845 |
| PCBP2 | poly(rC) binding protein 2 | 0.0408891 |
| PRELID2 | PRELI domain containing 2 | 0.0406754 |
| PATJ | PATJ crumbs cell polarity complex component | 0.0404543 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0404238 |
| YTHDC1 | YTH domain containing 1 | 0.038958 |
| ZNF654 | zinc finger protein 654 | 0.0386348 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0382926 |
| FOXO3 | forkhead box O3 | 0.0380401 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0379935 |
| BRD2 | bromodomain containing 2 | 0.0378268 |
| GOLGB1 | golgin B1 | 0.037408 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0368649 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0361407 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0361369 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0359096 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0358623 |
| SUCO | SUN domain containing ossification factor | 0.0358278 |
| FNIP1 | folliculin interacting protein 1 | 0.0358264 |
| FLNB | filamin B, beta | 0.0357513 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0352287 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0352213 |
| OGA | O-GlcNAcase | 0.0346284 |
| SET | SET nuclear proto-oncogene | 0.0344526 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0343884 |
| ZNF292 | zinc finger protein 292 | 0.0343526 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0341624 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0338908 |
| PFKP | phosphofructokinase, platelet | 0.0338261 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0337257 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0334975 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0333137 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0332497 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0331119 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0330385 |
| SEPTIN7 | septin 7 | 0.0330046 |
| CORO1C | coronin, actin binding protein, 1C | 0.0329498 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0327051 |
| Symbol | Name | Standardized Value |
|---|---|---|
| RPL35A | ribosomal protein L35a | -0.0793011 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.061678 |
| TMSB10 | thymosin beta 10 | -0.0451955 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0430502 |
| RPS21 | ribosomal protein S21 | -0.0413057 |
| RPS19 | ribosomal protein S19 | -0.0355865 |
| RPL37A | ribosomal protein L37a | -0.0350843 |
| RPS6 | ribosomal protein S6 | -0.0346378 |
| RPL34 | ribosomal protein L34 | -0.0328474 |
| RPL11 | ribosomal protein L11 | -0.0323047 |
| RPLP1 | ribosomal protein, large, P1 | -0.029926 |
| RPLP0 | ribosomal protein, large, P0 | -0.0296637 |
| RPS15 | ribosomal protein S15 | -0.0296245 |
| RPS24 | ribosomal protein S24 | -0.0283742 |
| RPL36 | ribosomal protein L36 | -0.0278171 |
| RPS16 | ribosomal protein S16 | -0.0270185 |
| RPL9 | ribosomal protein L9 | -0.0265603 |
| RPS20 | ribosomal protein S20 | -0.0249879 |
| RPL23 | ribosomal protein L23 | -0.0249027 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0248305 |
| RPL38 | ribosomal protein L38 | -0.0247586 |
| RPS27A | ribosomal protein S27a | -0.0238811 |
| FHIT | fragile histidine triad | -0.0227387 |
| RPS28 | ribosomal protein S28 | -0.0227211 |
| RPLP2 | ribosomal protein, large, P2 | -0.0223963 |
| RPL26 | ribosomal protein L26 | -0.0214398 |
| RPS8 | ribosomal protein S8 | -0.0212773 |
| SRP72 | signal recognition particle 72kDa | -0.0211672 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0209796 |
| RPL27 | ribosomal protein L27 | -0.020894 |
| RPS23 | ribosomal protein S23 | -0.0200376 |
| AGPAT3 | 1-acylglycerol-3-phosphate O-acyltransferase 3 | -0.0192581 |
| RRBP1 | ribosome binding protein 1 | -0.0189974 |
| ZC3H12B | zinc finger CCCH-type containing 12B | -0.0184445 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0177791 |
| RPL30 | ribosomal protein L30 | -0.0175803 |
| RPS10 | ribosomal protein S10 | -0.0174518 |
| RPL12 | ribosomal protein L12 | -0.0169984 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0168656 |
| EEF1D | eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) | -0.0168361 |
| RPL32 | ribosomal protein L32 | -0.0167768 |
| HMGA1 | high mobility group AT-hook 1 | -0.0165848 |
| RPS25 | ribosomal protein S25 | -0.0165753 |
| GNAS | GNAS complex locus | -0.0162292 |
| PPP2CA | protein phosphatase 2, catalytic subunit, alpha isozyme | -0.0162104 |
| PRDX1 | peroxiredoxin 1 | -0.0161249 |
| HOXB3 | homeobox B3 | -0.0159116 |
| LARP1B | La ribonucleoprotein domain family, member 1B | -0.0158875 |
| RPL28 | ribosomal protein L28 | -0.0158294 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0157874 |
| EWSR1 | EWS RNA-binding protein 1 | -0.0156788 |
| WWOX | WW domain containing oxidoreductase | -0.0156717 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0155985 |
| SAP18 | Sin3A-associated protein, 18kDa | -0.015571 |
| RPL8 | ribosomal protein L8 | -0.0155203 |
| RPL27A | ribosomal protein L27a | -0.0154986 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0154781 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.014721 |
| SRSF6 | serine/arginine-rich splicing factor 6 | -0.0146609 |
| NDUFA4 | NDUFA4, mitochondrial complex associated | -0.0145033 |
| HDAC8 | histone deacetylase 8 | -0.0140221 |
| RPL7 | ribosomal protein L7 | -0.0139088 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | -0.0135825 |
| NACA | nascent polypeptide-associated complex alpha subunit | -0.0134266 |
| HMGB1 | high mobility group box 1 | -0.0132923 |
| SLC25A5 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | -0.0130718 |
| PHF14 | PHD finger protein 14 | -0.0130628 |
| TMED2 | transmembrane emp24 domain trafficking protein 2 | -0.0129392 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0128869 |
| RBM3 | RNA binding motif (RNP1, RRM) protein 3 | -0.0128743 |
| RPS29 | ribosomal protein S29 | -0.0128477 |
| HIBCH | 3-hydroxyisobutyryl-CoA hydrolase | -0.0127259 |
| VWA8 | von Willebrand factor A domain containing 8 | -0.0126981 |
| CUL1 | cullin 1 | -0.0126475 |
| MACROH2A1 | macroH2A.1 histone | -0.0124868 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.012399 |
| MANF | mesencephalic astrocyte-derived neurotrophic factor | -0.0123539 |
| TFRC | transferrin receptor | -0.0123307 |
| BBS9 | Bardet-Biedl syndrome 9 | -0.0122831 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -0.0122411 |
| HLA-B | major histocompatibility complex, class I, B | -0.0121752 |
| ZNF33A | zinc finger protein 33A | -0.0121703 |
| GSTP1 | glutathione S-transferase pi 1 | -0.0121523 |
| GALK2 | galactokinase 2 | -0.0121291 |
| RSL24D1 | ribosomal L24 domain containing 1 | -0.0120426 |
| EIF4H | eukaryotic translation initiation factor 4H | -0.0118496 |
| FGFRL1 | fibroblast growth factor receptor-like 1 | -0.0118408 |
| ELP4 | elongator acetyltransferase complex subunit 4 | -0.0117744 |
| SMIM14 | small integral membrane protein 14 | -0.0117673 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0117085 |
| SSB | Sjogren syndrome antigen B (autoantigen La) | -0.0115113 |
| IZUMO1 | izumo sperm-egg fusion 1 | -0.0115081 |
| RNF216 | ring finger protein 216 | -0.0114929 |
| HLCS | holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase) | -0.0114168 |
| RPL36AL | ribosomal protein L36a-like | -0.0114148 |
| RPL31 | ribosomal protein L31 | -0.0113407 |
| TEX14 | testis expressed 14 | -0.0112033 |
| TOMM7 | translocase of outer mitochondrial membrane 7 homolog (yeast) | -0.0112001 |
| PPP6R2 | protein phosphatase 6, regulatory subunit 2 | -0.011145 |
| ERCC6L2 | excision repair cross-complementation group 6-like 2 | -0.0110133 |
