| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | L-Eflornithine (monohydrochloride) perturbation in HEC-1-A cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the L-Eflornithine (monohydrochloride)_HEC-1-A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ASPH | aspartate beta-hydroxylase | 0.187145 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.123902 |
| ENO1 | enolase 1, (alpha) | 0.111664 |
| PRELID2 | PRELI domain containing 2 | 0.0986814 |
| AHNAK | AHNAK nucleoprotein | 0.095467 |
| PAX8 | paired box 8 | 0.0927622 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0896924 |
| LDHA | lactate dehydrogenase A | 0.089498 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0855897 |
| POTEF | POTE ankyrin domain family, member F | 0.0855177 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0807492 |
| ITGB8 | integrin, beta 8 | 0.0778735 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0751331 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0745855 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.0727312 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0716719 |
| PKM | pyruvate kinase, muscle | 0.0715188 |
| SVIL | supervillin | 0.0700469 |
| ANXA2 | annexin A2 | 0.0683153 |
| MKI67 | marker of proliferation Ki-67 | 0.0677142 |
| APP | amyloid beta (A4) precursor protein | 0.0671669 |
| ACTG1 | actin gamma 1 | 0.0670534 |
| CD44 | CD44 molecule (Indian blood group) | 0.0638257 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0637142 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0631792 |
| TPM4 | tropomyosin 4 | 0.0622529 |
| RAD51B | RAD51 paralog B | 0.0622366 |
| LAMC2 | laminin, gamma 2 | 0.0615033 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0598761 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0577755 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0571084 |
| KRT7 | keratin 7, type II | 0.0570098 |
| ECT2 | epithelial cell transforming 2 | 0.0552378 |
| SEPTIN9 | septin 9 | 0.0549429 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0535464 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.05247 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0517482 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | 0.0496884 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0496672 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0495398 |
| VCAN | versican | 0.0494894 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0490265 |
| MYOF | myoferlin | 0.0488384 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0482695 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0480636 |
| EGFR | epidermal growth factor receptor | 0.0479293 |
| PATJ | PATJ crumbs cell polarity complex component | 0.0474201 |
| DLC1 | DLC1 Rho GTPase activating protein | 0.047401 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0468337 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0463925 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0463914 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0463533 |
| HMGA2 | high mobility group AT-hook 2 | 0.0456532 |
| UBC | ubiquitin C | 0.0454147 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.045137 |
| BPTF | bromodomain PHD finger transcription factor | 0.0449779 |
| FNIP1 | folliculin interacting protein 1 | 0.0442194 |
| SETD5 | SET domain containing 5 | 0.0441534 |
| SET | SET nuclear proto-oncogene | 0.0438556 |
| FLNB | filamin B, beta | 0.0428746 |
| FNDC3B | fibronectin type III domain containing 3B | 0.042062 |
| EZR | ezrin | 0.0419754 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.041963 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0418359 |
| HELZ | helicase with zinc finger | 0.0416957 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0416215 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0416194 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0414728 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0411857 |
| FNBP1L | formin binding protein 1-like | 0.0409532 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0407889 |
| CREB5 | cAMP responsive element binding protein 5 | 0.0402969 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0400198 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0395495 |
| CANX | calnexin | 0.0385254 |
| WWC1 | WW and C2 domain containing 1 | 0.0385113 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.037715 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0376803 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.0373901 |
| BBX | bobby sox homolog (Drosophila) | 0.0372387 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0371583 |
| DIAPH3 | diaphanous-related formin 3 | 0.0366823 |
| RACK1 | receptor for activated C kinase 1 | 0.0364632 |
| H1-0 | H1.0 linker histone | 0.0361972 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0360433 |
| ANXA1 | annexin A1 | 0.0359155 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0357938 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.035539 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0352115 |
| ANXA3 | annexin A3 | 0.0351713 |
| CD2AP | CD2-associated protein | 0.0351585 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0350794 |
| LAMA4 | laminin, alpha 4 | 0.0349403 |
| FHIT | fragile histidine triad | 0.0346714 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0345873 |
| DARS1 | aspartyl-tRNA synthetase 1 | 0.0344995 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0342485 |
| RPL3 | ribosomal protein L3 | 0.0341585 |
| ERBIN | erbb2 interacting protein | 0.0340435 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0340073 |
| Symbol | Name | Standardized Value |
|---|---|---|
| RPL35A | ribosomal protein L35a | -0.0897783 |
| RPS19 | ribosomal protein S19 | -0.0542442 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0539143 |
| RPLP1 | ribosomal protein, large, P1 | -0.0451658 |
| RPL31 | ribosomal protein L31 | -0.0436394 |
| RPL9 | ribosomal protein L9 | -0.0411689 |
| TMSB10 | thymosin beta 10 | -0.0407312 |
| RPLP2 | ribosomal protein, large, P2 | -0.0395087 |
| RPL32 | ribosomal protein L32 | -0.0340305 |
| RPS15 | ribosomal protein S15 | -0.0336482 |
| RPL11 | ribosomal protein L11 | -0.0329571 |
| RPL37A | ribosomal protein L37a | -0.0319324 |
| RPL36 | ribosomal protein L36 | -0.0319089 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0318005 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0315241 |
| RPS21 | ribosomal protein S21 | -0.0294706 |
| RPL23 | ribosomal protein L23 | -0.0288579 |
| RPL26 | ribosomal protein L26 | -0.0283079 |
| EGR1 | early growth response 1 | -0.0256943 |
| RPL35 | ribosomal protein L35 | -0.0247407 |
| RPL19 | ribosomal protein L19 | -0.0238592 |
| RPL38 | ribosomal protein L38 | -0.0234138 |
| RPS10 | ribosomal protein S10 | -0.0232354 |
| RPL12 | ribosomal protein L12 | -0.0228244 |
| RPS23 | ribosomal protein S23 | -0.0225291 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0217682 |
| RPS25 | ribosomal protein S25 | -0.0216749 |
| RPL30 | ribosomal protein L30 | -0.0212154 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | -0.0211902 |
| NDFIP1 | Nedd4 family interacting protein 1 | -0.0203829 |
| RPS16 | ribosomal protein S16 | -0.0200652 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0200589 |
| RPS27A | ribosomal protein S27a | -0.0195458 |
| RPL28 | ribosomal protein L28 | -0.0186477 |
| RPS29 | ribosomal protein S29 | -0.0185534 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | -0.0182373 |
| RPS17 | ribosomal protein S17 | -0.0176576 |
| RPS13 | ribosomal protein S13 | -0.0173118 |
| RPS6 | ribosomal protein S6 | -0.0169922 |
| RPS12 | ribosomal protein S12 | -0.0169443 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0166169 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.0165632 |
| VIM | vimentin | -0.0162473 |
| RPL27 | ribosomal protein L27 | -0.0162468 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0161628 |
| RPS24 | ribosomal protein S24 | -0.0160385 |
| PPP2CA | protein phosphatase 2, catalytic subunit, alpha isozyme | -0.0156803 |
| HLA-C | major histocompatibility complex, class I, C | -0.0156025 |
| RPL34 | ribosomal protein L34 | -0.0155632 |
| RPL5 | ribosomal protein L5 | -0.0154389 |
| LMNA | lamin A/C | -0.015325 |
| RPS11 | ribosomal protein S11 | -0.0152861 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0152806 |
| RRBP1 | ribosome binding protein 1 | -0.0152733 |
| COX6B1 | cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous) | -0.0149688 |
| GUK1 | guanylate kinase 1 | -0.0148848 |
| SEC61G | Sec61 gamma subunit | -0.0148044 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.014682 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | -0.0145525 |
| UBE2B | ubiquitin-conjugating enzyme E2B | -0.0143462 |
| RPL7A | ribosomal protein L7a | -0.0143009 |
| RPS8 | ribosomal protein S8 | -0.0142301 |
| RPL36A | ribosomal protein L36a | -0.0136213 |
| MTCH1 | mitochondrial carrier 1 | -0.0134119 |
| TCF25 | transcription factor 25 (basic helix-loop-helix) | -0.0133966 |
| TNRC6A | trinucleotide repeat containing 6A | -0.0132833 |
| NDUFA4 | NDUFA4, mitochondrial complex associated | -0.0130331 |
| RPL37 | ribosomal protein L37 | -0.0129084 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0127894 |
| UQCRQ | ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa | -0.01261 |
| COX4I1 | cytochrome c oxidase subunit IV isoform 1 | -0.0125818 |
| TMEM165 | transmembrane protein 165 | -0.0124429 |
| UBQLN1 | ubiquilin 1 | -0.0123902 |
| SEC62 | SEC62 homolog (S. cerevisiae) | -0.0118924 |
| NOP53 | NOP53 ribosome biogenesis factor | -0.0117873 |
| CKS2 | CDC28 protein kinase regulatory subunit 2 | -0.0115669 |
| TMEM167A | transmembrane protein 167A | -0.0115191 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | -0.0114345 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0113627 |
| NDUFA1 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa | -0.0113589 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | -0.0113299 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0112473 |
| ATF4 | activating transcription factor 4 | -0.0112434 |
| CELF1 | CUGBP, Elav-like family member 1 | -0.0111983 |
| SELENOK | selenoprotein K | -0.0111351 |
| CCL20 | chemokine (C-C motif) ligand 20 | -0.0111018 |
| RPS20 | ribosomal protein S20 | -0.011091 |
| POMP | proteasome maturation protein | -0.0110516 |
| QRICH1 | glutamine-rich 1 | -0.0110469 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0109937 |
| GORASP2 | golgi reassembly stacking protein 2, 55kDa | -0.0109604 |
| RAN | RAN, member RAS oncogene family | -0.0109224 |
| ATP5F1E | ATP synthase F1 subunit epsilon | -0.0109164 |
| LAMTOR5 | late endosomal/lysosomal adaptor, MAPK and MTOR activator 5 | -0.0108678 |
| SVIP | small VCP/p97-interacting protein | -0.0108036 |
| TMEM41B | transmembrane protein 41B | -0.0107718 |
| GPX4 | glutathione peroxidase 4 | -0.0106201 |
| CLCC1 | chloride channel CLIC-like 1 | -0.0105808 |
| GSTP1 | glutathione S-transferase pi 1 | -0.0105468 |
| LITAF | lipopolysaccharide-induced TNF factor | -0.0105168 |
