| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | L-Eflornithine (monohydrochloride) perturbation in HOP62 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the L-Eflornithine (monohydrochloride)_HOP62 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.290146 |
| FN1 | fibronectin 1 | 0.116202 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.105372 |
| VEGFA | vascular endothelial growth factor A | 0.0974208 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0726409 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0671809 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0647248 |
| SPAG9 | sperm associated antigen 9 | 0.0628126 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0577538 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0539427 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0537102 |
| VCL | vinculin | 0.0527049 |
| EGR1 | early growth response 1 | 0.0504563 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0497463 |
| NGLY1 | N-glycanase 1 | 0.0491977 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0421734 |
| MSN | moesin | 0.0404749 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0401797 |
| SEPTIN9 | septin 9 | 0.0399769 |
| DUSP6 | dual specificity phosphatase 6 | 0.0399527 |
| LOX | lysyl oxidase | 0.0395557 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0366881 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0357635 |
| OGA | O-GlcNAcase | 0.0356518 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0356007 |
| PTMA | prothymosin, alpha | 0.0353965 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 0.0331614 |
| RPL3 | ribosomal protein L3 | 0.0320269 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0304839 |
| RBM39 | RNA binding motif protein 39 | 0.03039 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0302866 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0302711 |
| COL6A2 | collagen, type VI, alpha 2 | 0.0301255 |
| STC1 | stanniocalcin 1 | 0.0293803 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0287789 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0273701 |
| NUMB | numb homolog (Drosophila) | 0.0268141 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | 0.0265034 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0260371 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0256881 |
| COPA | coatomer protein complex, subunit alpha | 0.0255009 |
| RTN4 | reticulon 4 | 0.0253196 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0250365 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0236782 |
| CUL4B | cullin 4B | 0.0233258 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0232094 |
| TMF1 | TATA element modulatory factor 1 | 0.0231234 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.022593 |
| PDE10A | phosphodiesterase 10A | 0.0225495 |
| HPCAL1 | hippocalcin-like 1 | 0.022504 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0224564 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 | 0.0224096 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0224054 |
| SBF2 | SET binding factor 2 | 0.0220335 |
| IGFBP4 | insulin-like growth factor binding protein 4 | 0.0218446 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0216348 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0213589 |
| MARCHF7 | membrane associated ring-CH-type finger 7 | 0.0210014 |
| MT1X | metallothionein 1X | 0.0206479 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0196587 |
| WDR45B | WD repeat domain 45B | 0.0193801 |
| SFTPA2 | surfactant protein A2 | 0.0192868 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0192707 |
| RLIM | ring finger protein, LIM domain interacting | 0.0188992 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.0188389 |
| TMEM263 | transmembrane protein 263 | 0.0187785 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.0185472 |
| MEF2A | myocyte enhancer factor 2A | 0.0184875 |
| LCORL | ligand dependent nuclear receptor corepressor-like | 0.0184089 |
| SUCO | SUN domain containing ossification factor | 0.0183445 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.018099 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0179644 |
| FAM13A | family with sequence similarity 13, member A | 0.0179469 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0177688 |
| INHBA | inhibin, beta A | 0.017729 |
| SEPTIN10 | septin 10 | 0.0177274 |
| CLIC4 | chloride intracellular channel 4 | 0.0176111 |
| SETD5 | SET domain containing 5 | 0.0175563 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0174719 |
| MAPK8 | mitogen-activated protein kinase 8 | 0.0174316 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.0173901 |
| YES1 | YES proto-oncogene 1, Src family tyrosine kinase | 0.0173749 |
| RAI1 | retinoic acid induced 1 | 0.0172219 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0172032 |
| RASA3 | RAS p21 protein activator 3 | 0.0171882 |
| NECTIN2 | nectin cell adhesion molecule 2 | 0.0171446 |
| SNX14 | sorting nexin 14 | 0.0170527 |
| MKI67 | marker of proliferation Ki-67 | 0.0169114 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0168639 |
| RAP1B | RAP1B, member of RAS oncogene family | 0.0168102 |
| INSIG1 | insulin induced gene 1 | 0.0168001 |
| TNS1 | tensin 1 | 0.0166835 |
| GOLT1B | golgi transport 1B | 0.0166525 |
| ARF4 | ADP-ribosylation factor 4 | 0.0166453 |
| PGK1 | phosphoglycerate kinase 1 | 0.01664 |
| CLTC | clathrin, heavy chain (Hc) | 0.0165578 |
| TMEM41B | transmembrane protein 41B | 0.016246 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.016187 |
| CAPRIN2 | caprin family member 2 | 0.0160237 |
| MIS18BP1 | MIS18 binding protein 1 | 0.0159706 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.41812 |
| VIM | vimentin | -0.354272 |
| TMSB10 | thymosin beta 10 | -0.116195 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.102752 |
| NDRG1 | N-myc downstream regulated 1 | -0.0911516 |
| RPS27A | ribosomal protein S27a | -0.0877299 |
| ENO1 | enolase 1, (alpha) | -0.087276 |
| AHNAK | AHNAK nucleoprotein | -0.0851629 |
| HMGA2 | high mobility group AT-hook 2 | -0.0807229 |
| UBC | ubiquitin C | -0.0714668 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0689639 |
| COL5A1 | collagen, type V, alpha 1 | -0.061263 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0512232 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0510804 |
| JUN | jun proto-oncogene | -0.0507897 |
| PCBP2 | poly(rC) binding protein 2 | -0.050462 |
| ASPH | aspartate beta-hydroxylase | -0.0475347 |
| RPL23 | ribosomal protein L23 | -0.0456976 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.044701 |
| MT2A | metallothionein 2A | -0.0440405 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0428529 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0405238 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0390914 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0388915 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0384568 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0384204 |
| ANXA2 | annexin A2 | -0.0366826 |
| SMYD3 | SET and MYND domain containing 3 | -0.0365216 |
| SFPQ | splicing factor proline/glutamine-rich | -0.0356438 |
| PLEC | plectin | -0.0350846 |
| FLNA | filamin A, alpha | -0.0349032 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.034373 |
| RPL37A | ribosomal protein L37a | -0.0342609 |
| PKM | pyruvate kinase, muscle | -0.0341535 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0322502 |
| RPL9 | ribosomal protein L9 | -0.0321529 |
| RPS6 | ribosomal protein S6 | -0.0319138 |
| LMNA | lamin A/C | -0.0317972 |
| NAV1 | neuron navigator 1 | -0.0311361 |
| RPLP1 | ribosomal protein, large, P1 | -0.0309678 |
| RPS8 | ribosomal protein S8 | -0.0309075 |
| IGF2 | insulin-like growth factor 2 | -0.0307842 |
| RPL12 | ribosomal protein L12 | -0.0305707 |
| MLPH | melanophilin | -0.0305403 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.0304356 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0299531 |
| RPS12 | ribosomal protein S12 | -0.0292109 |
| TXNRD1 | thioredoxin reductase 1 | -0.0277181 |
| NAV3 | neuron navigator 3 | -0.0273778 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0272812 |
| GLIS3 | GLIS family zinc finger 3 | -0.0271453 |
| MYO10 | myosin X | -0.0266306 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0263359 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0261427 |
| TPM1 | tropomyosin 1 (alpha) | -0.0258719 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0251866 |
| COL1A1 | collagen, type I, alpha 1 | -0.0248813 |
| CDK6 | cyclin-dependent kinase 6 | -0.0247237 |
| GNAS | GNAS complex locus | -0.0246402 |
| ACTN4 | actinin, alpha 4 | -0.0246063 |
| RPS20 | ribosomal protein S20 | -0.0244933 |
| RPL11 | ribosomal protein L11 | -0.0242937 |
| ATXN1 | ataxin 1 | -0.0242261 |
| HMGA1 | high mobility group AT-hook 1 | -0.0236977 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0236903 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0234106 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0232502 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0223879 |
| RPLP0 | ribosomal protein, large, P0 | -0.0223452 |
| RPL28 | ribosomal protein L28 | -0.0220044 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.02191 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0218404 |
| RPS16 | ribosomal protein S16 | -0.0217896 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0215401 |
| SMAD3 | SMAD family member 3 | -0.0214777 |
| RPL15 | ribosomal protein L15 | -0.0212872 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0211365 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0211125 |
| TXNIP | thioredoxin interacting protein | -0.0210218 |
| EMP1 | epithelial membrane protein 1 | -0.0208876 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0206556 |
| WWOX | WW domain containing oxidoreductase | -0.0206461 |
| ERGIC1 | endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1 | -0.020547 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0204356 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0201441 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0198896 |
| RPL19 | ribosomal protein L19 | -0.0198087 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0196752 |
| PTK2 | protein tyrosine kinase 2 | -0.0195245 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.0193687 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0191212 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.019115 |
| RPS19 | ribosomal protein S19 | -0.0190748 |
| NRP1 | neuropilin 1 | -0.0188721 |
| UBB | ubiquitin B | -0.0188334 |
| RPL35A | ribosomal protein L35a | -0.0187267 |
| RPL36A | ribosomal protein L36a | -0.018497 |
| RPL5 | ribosomal protein L5 | -0.0184501 |
| NSMCE2 | non-SMC element 2, MMS21 homolog (S. cerevisiae) | -0.0180606 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0180215 |
