| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | L-Eflornithine (monohydrochloride) perturbation in HS-578T cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the L-Eflornithine (monohydrochloride)_HS-578T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VEGFA | vascular endothelial growth factor A | 0.263325 |
| COL6A3 | collagen, type VI, alpha 3 | 0.224941 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.153107 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.150921 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.108224 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.104055 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0995166 |
| FN1 | fibronectin 1 | 0.0937839 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0927338 |
| CALR | calreticulin | 0.0889794 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0883235 |
| UBC | ubiquitin C | 0.0858468 |
| LDHA | lactate dehydrogenase A | 0.0823321 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0747647 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0745685 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0695377 |
| PDE10A | phosphodiesterase 10A | 0.0689278 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0685626 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0685149 |
| CANX | calnexin | 0.0644964 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0611256 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0603791 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.059977 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0591532 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.058559 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0562579 |
| GOLGA4 | golgin A4 | 0.052317 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0509368 |
| COL5A1 | collagen, type V, alpha 1 | 0.049661 |
| NAV2 | neuron navigator 2 | 0.0493707 |
| ENO1 | enolase 1, (alpha) | 0.0485542 |
| VMP1 | vacuole membrane protein 1 | 0.0484876 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0464767 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0453568 |
| VCAN | versican | 0.0434387 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.042783 |
| CADM1 | cell adhesion molecule 1 | 0.0424174 |
| RPL3 | ribosomal protein L3 | 0.0423738 |
| MT1X | metallothionein 1X | 0.0417479 |
| TMEM165 | transmembrane protein 165 | 0.0416075 |
| SPAG9 | sperm associated antigen 9 | 0.0408732 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0408327 |
| MSN | moesin | 0.0406079 |
| ARRDC3 | arrestin domain containing 3 | 0.0401364 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0399428 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0386787 |
| SDC2 | syndecan 2 | 0.0383289 |
| COPA | coatomer protein complex, subunit alpha | 0.0382959 |
| FNIP1 | folliculin interacting protein 1 | 0.0382245 |
| LOX | lysyl oxidase | 0.038172 |
| CD44 | CD44 molecule (Indian blood group) | 0.0377532 |
| FBN1 | fibrillin 1 | 0.0369728 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0368291 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0360242 |
| TMF1 | TATA element modulatory factor 1 | 0.0357755 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0357367 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0355816 |
| ATP13A3 | ATPase type 13A3 | 0.0353068 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0350924 |
| GOLGB1 | golgin B1 | 0.0349599 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0347507 |
| SQLE | squalene epoxidase | 0.0343794 |
| INHBA | inhibin, beta A | 0.0337053 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0333389 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0332998 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0330948 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0327217 |
| MYO10 | myosin X | 0.032658 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0323844 |
| HYOU1 | hypoxia up-regulated 1 | 0.0320585 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0319965 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0317687 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0314617 |
| SETD5 | SET domain containing 5 | 0.031195 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0310545 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.029919 |
| RASA2 | RAS p21 protein activator 2 | 0.0298007 |
| DST | dystonin | 0.0294887 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0292039 |
| CD109 | CD109 molecule | 0.0291705 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0291279 |
| PTK2 | protein tyrosine kinase 2 | 0.0290279 |
| AXL | AXL receptor tyrosine kinase | 0.0289586 |
| WASF2 | WAS protein family, member 2 | 0.0289292 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0287034 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0281802 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0276584 |
| NOTCH2 | notch 2 | 0.0275389 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0272156 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0270502 |
| RUNX1 | runt-related transcription factor 1 | 0.026953 |
| TNS1 | tensin 1 | 0.0268263 |
| TBC1D23 | TBC1 domain family, member 23 | 0.0266528 |
| B2M | beta-2-microglobulin | 0.0266466 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0265663 |
| FMNL2 | formin-like 2 | 0.0264235 |
| OGA | O-GlcNAcase | 0.0262417 |
| DSPP | dentin sialophosphoprotein | 0.0258844 |
| SUCO | SUN domain containing ossification factor | 0.0256441 |
| GDI2 | GDP dissociation inhibitor 2 | 0.0256352 |
| Symbol | Name | Standardized Value |
|---|---|---|
| COL1A1 | collagen, type I, alpha 1 | -0.171828 |
| RPL35A | ribosomal protein L35a | -0.104738 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.10185 |
| VIM | vimentin | -0.0852313 |
| TMSB10 | thymosin beta 10 | -0.0816619 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0654512 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | -0.0601601 |
| IER3 | immediate early response 3 | -0.0590635 |
| HLA-B | major histocompatibility complex, class I, B | -0.0555904 |
| RPS8 | ribosomal protein S8 | -0.0525688 |
| RPL11 | ribosomal protein L11 | -0.051169 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0470011 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.043624 |
| LOXL2 | lysyl oxidase-like 2 | -0.0431474 |
| ACTG1 | actin gamma 1 | -0.0430439 |
| CAVIN1 | caveolae associated protein 1 | -0.0426597 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0387449 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0368181 |
| RPL37A | ribosomal protein L37a | -0.0361366 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0346139 |
| RPS6 | ribosomal protein S6 | -0.0340716 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0338208 |
| RPL34 | ribosomal protein L34 | -0.0334118 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0327965 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0319237 |
| HMGA2 | high mobility group AT-hook 2 | -0.0314317 |
| RRBP1 | ribosome binding protein 1 | -0.0310222 |
| RPS20 | ribosomal protein S20 | -0.0306183 |
| S100A9 | S100 calcium binding protein A9 | -0.0302647 |
| RPLP1 | ribosomal protein, large, P1 | -0.0296255 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.029504 |
| FTL | ferritin, light polypeptide | -0.0293371 |
| RPS24 | ribosomal protein S24 | -0.0284646 |
| RPL28 | ribosomal protein L28 | -0.0280754 |
| RPL30 | ribosomal protein L30 | -0.0278692 |
| VDAC1 | voltage-dependent anion channel 1 | -0.027748 |
| RPS21 | ribosomal protein S21 | -0.0276951 |
| LMNA | lamin A/C | -0.0274264 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0273153 |
| RPS25 | ribosomal protein S25 | -0.0272116 |
| RPLP2 | ribosomal protein, large, P2 | -0.0270071 |
| TPM4 | tropomyosin 4 | -0.0257069 |
| EEF1D | eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) | -0.0254486 |
| GNAS | GNAS complex locus | -0.0254381 |
| RPL9 | ribosomal protein L9 | -0.0252691 |
| RPL26 | ribosomal protein L26 | -0.023903 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0235713 |
| SEC61G | Sec61 gamma subunit | -0.022974 |
| OSMR | oncostatin M receptor | -0.022867 |
| RPL31 | ribosomal protein L31 | -0.0224552 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0223645 |
| RPS5 | ribosomal protein S5 | -0.022334 |
| RPS23 | ribosomal protein S23 | -0.0222276 |
| RPS16 | ribosomal protein S16 | -0.0219778 |
| NDRG1 | N-myc downstream regulated 1 | -0.0219022 |
| RPS13 | ribosomal protein S13 | -0.0215086 |
| COL1A2 | collagen, type I, alpha 2 | -0.0213556 |
| RPL23 | ribosomal protein L23 | -0.0212284 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0211583 |
| RPL38 | ribosomal protein L38 | -0.0208466 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0202766 |
| RPS19 | ribosomal protein S19 | -0.0200333 |
| RPS15 | ribosomal protein S15 | -0.019929 |
| ANXA2 | annexin A2 | -0.0198446 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | -0.0196867 |
| RPS14 | ribosomal protein S14 | -0.0196495 |
| FOXP1 | forkhead box P1 | -0.0191861 |
| OAZ1 | ornithine decarboxylase antizyme 1 | -0.018744 |
| RPS10 | ribosomal protein S10 | -0.0186759 |
| RPL36 | ribosomal protein L36 | -0.0186739 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0186449 |
| IL6ST | interleukin 6 signal transducer | -0.0184576 |
| RPLP0 | ribosomal protein, large, P0 | -0.0184178 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0182488 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0175416 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0171365 |
| MX2 | MX dynamin-like GTPase 2 | -0.0170568 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0170349 |
| TOMM7 | translocase of outer mitochondrial membrane 7 homolog (yeast) | -0.0165919 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0164843 |
| PTMA | prothymosin, alpha | -0.0163344 |
| CD63 | CD63 molecule | -0.0163234 |
| ARF1 | ADP-ribosylation factor 1 | -0.0156452 |
| PXDN | peroxidasin | -0.0155948 |
| PIEZO2 | piezo-type mechanosensitive ion channel component 2 | -0.0154611 |
| ATG7 | autophagy related 7 | -0.0153858 |
| RPS29 | ribosomal protein S29 | -0.0153508 |
| STC1 | stanniocalcin 1 | -0.015219 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0150716 |
| RPL5 | ribosomal protein L5 | -0.0150583 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0148697 |
| HLA-C | major histocompatibility complex, class I, C | -0.0147151 |
| MYDGF | myeloid-derived growth factor | -0.014395 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0143491 |
| SYNJ2 | synaptojanin 2 | -0.0143268 |
| RIGI | RNA sensor RIG-I | -0.014324 |
| AGPAT3 | 1-acylglycerol-3-phosphate O-acyltransferase 3 | -0.0141706 |
| RPS27A | ribosomal protein S27a | -0.0137581 |
| RPL36A | ribosomal protein L36a | -0.0137184 |
| FHL2 | four and a half LIM domains 2 | -0.0136657 |
