| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | L-Eflornithine (monohydrochloride) perturbation in HT-29 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the L-Eflornithine (monohydrochloride)_HT-29 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AHNAK | AHNAK nucleoprotein | 0.0886674 |
| KRT8 | keratin 8, type II | 0.0809642 |
| NDRG1 | N-myc downstream regulated 1 | 0.07374 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0710435 |
| EZR | ezrin | 0.0706335 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.0701074 |
| SAMD12 | sterile alpha motif domain containing 12 | 0.0680384 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0667424 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0662345 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0659126 |
| PTMA | prothymosin, alpha | 0.0648315 |
| ACTN4 | actinin, alpha 4 | 0.064135 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0625665 |
| ANXA2 | annexin A2 | 0.0621437 |
| FRY | furry homolog (Drosophila) | 0.0612532 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0582666 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.055735 |
| NECTIN2 | nectin cell adhesion molecule 2 | 0.0537388 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0518478 |
| ASPH | aspartate beta-hydroxylase | 0.0505938 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0483505 |
| PTK2 | protein tyrosine kinase 2 | 0.0482073 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0482013 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0476329 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0470871 |
| PGK1 | phosphoglycerate kinase 1 | 0.045483 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0453524 |
| TXNRD1 | thioredoxin reductase 1 | 0.0443162 |
| KRT18 | keratin 18, type I | 0.0433392 |
| VEGFA | vascular endothelial growth factor A | 0.042945 |
| ENO1 | enolase 1, (alpha) | 0.0428833 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0424672 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0420629 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0415784 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0410957 |
| CCSER1 | coiled-coil serine-rich protein 1 | 0.0401664 |
| PRELID2 | PRELI domain containing 2 | 0.0395643 |
| MCL1 | myeloid cell leukemia 1 | 0.0386499 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0386378 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0379931 |
| LDHA | lactate dehydrogenase A | 0.0373846 |
| KRT19 | keratin 19, type I | 0.0373187 |
| DIAPH2 | diaphanous-related formin 2 | 0.0368697 |
| DSPP | dentin sialophosphoprotein | 0.0354635 |
| KLF3 | Kruppel-like factor 3 (basic) | 0.0348805 |
| LAMB3 | laminin, beta 3 | 0.0345903 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0339994 |
| EPCAM | epithelial cell adhesion molecule | 0.0337813 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.0332127 |
| MSN | moesin | 0.0328226 |
| UBC | ubiquitin C | 0.0326591 |
| YAP1 | Yes-associated protein 1 | 0.0323346 |
| FBXO32 | F-box protein 32 | 0.0323234 |
| RTN4 | reticulon 4 | 0.0315453 |
| ITGA6 | integrin, alpha 6 | 0.0314075 |
| PKM | pyruvate kinase, muscle | 0.0311441 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0308016 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | 0.0307079 |
| ITPKC | inositol-trisphosphate 3-kinase C | 0.0300319 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.029925 |
| FAT1 | FAT atypical cadherin 1 | 0.0296452 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0292256 |
| CTTN | cortactin | 0.0289785 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0289562 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0281516 |
| OGA | O-GlcNAcase | 0.0279588 |
| ATXN1 | ataxin 1 | 0.0279527 |
| APP | amyloid beta (A4) precursor protein | 0.0276286 |
| TRPS1 | trichorhinophalangeal syndrome I | 0.0266493 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | 0.0264338 |
| FOXO3 | forkhead box O3 | 0.026391 |
| KRT20 | keratin 20, type I | 0.0263886 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0261843 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | 0.0261649 |
| GNGT1 | guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 | 0.0257328 |
| SET | SET nuclear proto-oncogene | 0.0254969 |
| SDC4 | syndecan 4 | 0.0253586 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0250354 |
| MUC13 | mucin 13, cell surface associated | 0.0249877 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0248182 |
| JUP | junction plakoglobin | 0.0246135 |
| CLTC | clathrin, heavy chain (Hc) | 0.0245894 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0245758 |
| HOXB3 | homeobox B3 | 0.0245127 |
| B2M | beta-2-microglobulin | 0.0244487 |
| TMEM45B | transmembrane protein 45B | 0.0244396 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0241332 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0241215 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0237349 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.0236905 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0236235 |
| SBF2 | SET binding factor 2 | 0.0235577 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0234411 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0231078 |
| ACTG1 | actin gamma 1 | 0.0230963 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | 0.0230758 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0229519 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0228613 |
| BBX | bobby sox homolog (Drosophila) | 0.0226446 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0226171 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | -0.0596979 |
| TJP1 | tight junction protein 1 | -0.0555698 |
| FTL | ferritin, light polypeptide | -0.04991 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.039804 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | -0.0397477 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | -0.0378286 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0375924 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0341002 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0319424 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | -0.0313915 |
| PGCKA1 | PDCD10 and GCKIII kinases associated 1 | -0.0293671 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0268538 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | -0.0249129 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0236797 |
| RPS25 | ribosomal protein S25 | -0.0214282 |
| ANKRD17 | ankyrin repeat domain 17 | -0.020733 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0203716 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0192951 |
| SGMS2 | sphingomyelin synthase 2 | -0.0191083 |
| MACC1 | metastasis associated in colon cancer 1 | -0.0190948 |
| TRAM1 | translocation associated membrane protein 1 | -0.0190569 |
| NTN4 | netrin 4 | -0.0189596 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0186102 |
| HKDC1 | hexokinase domain containing 1 | -0.0178284 |
| MYO1E | myosin IE | -0.0177224 |
| RPL35A | ribosomal protein L35a | -0.0175359 |
| UBE2B | ubiquitin-conjugating enzyme E2B | -0.0174985 |
| SLC30A7 | solute carrier family 30 (zinc transporter), member 7 | -0.017084 |
| OCLN | occludin | -0.0168313 |
| ZNF207 | zinc finger protein 207 | -0.0166466 |
| B4GALNT3 | beta-1,4-N-acetyl-galactosaminyl transferase 3 | -0.0164219 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0163947 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.0161024 |
| AHCYL1 | adenosylhomocysteinase-like 1 | -0.0157353 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | -0.0156877 |
| RPL19 | ribosomal protein L19 | -0.0156326 |
| TMCO3 | transmembrane and coiled-coil domains 3 | -0.0156217 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.0156061 |
| ARHGAP42 | Rho GTPase activating protein 42 | -0.015519 |
| RPS19 | ribosomal protein S19 | -0.0151418 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.0149524 |
| RND3 | Rho family GTPase 3 | -0.0147714 |
| RAB3IP | RAB3A interacting protein | -0.0146195 |
| NUP98 | nucleoporin 98kDa | -0.01449 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0144314 |
| ATF4 | activating transcription factor 4 | -0.0143908 |
| ASTN2 | astrotactin 2 | -0.0136386 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0135022 |
| TMEM87A | transmembrane protein 87A | -0.0134142 |
| FHL2 | four and a half LIM domains 2 | -0.0133289 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | -0.013143 |
| TOX3 | TOX high mobility group box family member 3 | -0.0129898 |
| UBE3C | ubiquitin protein ligase E3C | -0.0128283 |
| PHACTR4 | phosphatase and actin regulator 4 | -0.0128276 |
| RNF24 | ring finger protein 24 | -0.0128033 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0127547 |
| WNT2B | wingless-type MMTV integration site family, member 2B | -0.0124852 |
| PRR5L | proline rich 5 like | -0.0124327 |
| PAQR5 | progestin and adipoQ receptor family member V | -0.0123811 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0122656 |
| TTC17 | tetratricopeptide repeat domain 17 | -0.0120535 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.0118665 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | -0.0117366 |
| FOXK1 | forkhead box K1 | -0.0116632 |
| RPL39 | ribosomal protein L39 | -0.0116207 |
| SEC24D | SEC24 family member D | -0.0115571 |
| INO80 | INO80 complex subunit | -0.0114664 |
| ARHGAP23 | Rho GTPase activating protein 23 | -0.0113785 |
| YARS1 | tyrosyl-tRNA synthetase 1 | -0.0112772 |
| PIBF1 | progesterone immunomodulatory binding factor 1 | -0.0112723 |
| SETX | senataxin | -0.0112336 |
| SCFD2 | sec1 family domain containing 2 | -0.0111819 |
| HSD17B2 | hydroxysteroid (17-beta) dehydrogenase 2 | -0.0111608 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.011097 |
| FAM193A | family with sequence similarity 193, member A | -0.0110906 |
| RPS6 | ribosomal protein S6 | -0.0110552 |
| SFSWAP | splicing factor, suppressor of white-apricot family | -0.0110484 |
| GLCCI1 | glucocorticoid induced 1 | -0.0110411 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0109261 |
| AGO2 | argonaute RISC catalytic component 2 | -0.0108653 |
| LRRC58 | leucine rich repeat containing 58 | -0.0108451 |
| KLF12 | Kruppel-like factor 12 | -0.0108017 |
| HIVEP1 | human immunodeficiency virus type I enhancer binding protein 1 | -0.010727 |
| FNBP4 | formin binding protein 4 | -0.0106888 |
| LURAP1L | leucine rich adaptor protein 1-like | -0.0106721 |
| RPS23 | ribosomal protein S23 | -0.0106629 |
| MAGT1 | magnesium transporter 1 | -0.0104808 |
| SULF2 | sulfatase 2 | -0.0104684 |
| HM13 | histocompatibility (minor) 13 | -0.0104626 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0104176 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 | -0.0104037 |
| DDX18 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 18 | -0.0103672 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0103461 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | -0.0103388 |
| OSBPL10 | oxysterol binding protein-like 10 | -0.0102936 |
| BCL2L1 | BCL2-like 1 | -0.0102156 |
| NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) | -0.0102152 |
| BLTP1 | bridge-like lipid transfer protein family member 1 | -0.0100715 |
| RPS5 | ribosomal protein S5 | -0.0100007 |
| CCT6A | chaperonin containing TCP1, subunit 6A (zeta 1) | -0.00987934 |
