| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | L-Eflornithine (monohydrochloride) perturbation in HepG2/C3A cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the L-Eflornithine (monohydrochloride)_HepG2/C3A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.200574 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.139186 |
| FN1 | fibronectin 1 | 0.127026 |
| SLC38A2 | solute carrier family 38, member 2 | 0.12354 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.116634 |
| APOB | apolipoprotein B | 0.100418 |
| VCL | vinculin | 0.0975624 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0775996 |
| C3 | complement component 3 | 0.07438 |
| DSPP | dentin sialophosphoprotein | 0.0737788 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0730844 |
| GPC3 | glypican 3 | 0.0717504 |
| ITGAV | integrin, alpha V | 0.0704895 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 0.0663888 |
| ARHGAP9 | Rho GTPase activating protein 9 | 0.0654303 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0629268 |
| VEGFA | vascular endothelial growth factor A | 0.0582716 |
| TRIM26 | tripartite motif containing 26 | 0.0562756 |
| PAWR | PRKC, apoptosis, WT1, regulator | 0.0546133 |
| FNDC3B | fibronectin type III domain containing 3B | 0.054453 |
| JMJD1C | jumonji domain containing 1C | 0.0536209 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0524681 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0514358 |
| GPAM | glycerol-3-phosphate acyltransferase, mitochondrial | 0.0512201 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0508888 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.050502 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | 0.0503378 |
| AFDN | afadin, adherens junction formation factor | 0.0502278 |
| MT2A | metallothionein 2A | 0.0494766 |
| VPS54 | vacuolar protein sorting 54 homolog (S. cerevisiae) | 0.0492039 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0490285 |
| DLC1 | DLC1 Rho GTPase activating protein | 0.0485085 |
| VMP1 | vacuole membrane protein 1 | 0.0484171 |
| MSI2 | musashi RNA-binding protein 2 | 0.0478221 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0473513 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0464088 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0449792 |
| SMAD3 | SMAD family member 3 | 0.0449421 |
| MALT1 | MALT1 paracaspase | 0.0430351 |
| ENO1 | enolase 1, (alpha) | 0.0416471 |
| FRMD5 | FERM domain containing 5 | 0.041566 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0409011 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0408827 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0392997 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0390942 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0387596 |
| KIF1B | kinesin family member 1B | 0.0385684 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | 0.0385221 |
| DENND4A | DENN/MADD domain containing 4A | 0.0381508 |
| MRTFA | myocardin related transcription factor A | 0.0381473 |
| RBM25 | RNA binding motif protein 25 | 0.037718 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0375425 |
| ZSWIM5 | zinc finger, SWIM-type containing 5 | 0.0375216 |
| RPL3 | ribosomal protein L3 | 0.0374574 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0365461 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0364689 |
| ENAH | enabled homolog (Drosophila) | 0.0364584 |
| ITGB5 | integrin, beta 5 | 0.0362191 |
| RBM39 | RNA binding motif protein 39 | 0.0362051 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.035513 |
| YTHDC1 | YTH domain containing 1 | 0.0353967 |
| BCL2L1 | BCL2-like 1 | 0.035147 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0341374 |
| LCOR | ligand dependent nuclear receptor corepressor | 0.0332028 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0331666 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0331423 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0327651 |
| CRLS1 | cardiolipin synthase 1 | 0.0325334 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0322069 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0320555 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0315753 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0312749 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0312566 |
| ABTB3 | ankyrin repeat and BTB domain containing 3 | 0.031156 |
| SVIL | supervillin | 0.0310975 |
| ARHGEF18 | Rho/Rac guanine nucleotide exchange factor (GEF) 18 | 0.0309899 |
| ABCA5 | ATP-binding cassette, sub-family A (ABC1), member 5 | 0.0309441 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | 0.030899 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0303002 |
| CPE | carboxypeptidase E | 0.0301466 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0300159 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0298828 |
| CUL3 | cullin 3 | 0.0296561 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | 0.0292633 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0292158 |
| DST | dystonin | 0.0288391 |
| RUNX1 | runt-related transcription factor 1 | 0.0283007 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0280954 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | 0.0276856 |
| RTN4 | reticulon 4 | 0.027552 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0273217 |
| MBNL3 | muscleblind-like splicing regulator 3 | 0.0271094 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0270695 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0269043 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0266409 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0265796 |
| SDC4 | syndecan 4 | 0.0261916 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.026124 |
| SPAG9 | sperm associated antigen 9 | 0.0260555 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 | 0.0260415 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGF2 | insulin-like growth factor 2 | -0.419844 |
| RPS8 | ribosomal protein S8 | -0.0628962 |
| RPL37A | ribosomal protein L37a | -0.0561582 |
| CCL20 | chemokine (C-C motif) ligand 20 | -0.0552027 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0537406 |
| GK | glycerol kinase | -0.0534922 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0520184 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0495279 |
| CP | ceruloplasmin (ferroxidase) | -0.0442511 |
| IGFBP1 | insulin-like growth factor binding protein 1 | -0.04413 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0426243 |
| RPS13 | ribosomal protein S13 | -0.0370886 |
| FTL | ferritin, light polypeptide | -0.0362356 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | -0.0317201 |
| DTNA | dystrobrevin, alpha | -0.0316979 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0285368 |
| RPL35A | ribosomal protein L35a | -0.0282857 |
| AHSG | alpha-2-HS-glycoprotein | -0.0280637 |
| RPL38 | ribosomal protein L38 | -0.0280635 |
| EHBP1 | EH domain binding protein 1 | -0.0279778 |
| RPS29 | ribosomal protein S29 | -0.0269377 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.0260272 |
| MAP1B | microtubule-associated protein 1B | -0.0259757 |
| RNF213 | ring finger protein 213 | -0.025662 |
| HDLBP | high density lipoprotein binding protein | -0.0255044 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.0250651 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0249821 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0247026 |
| RPL32 | ribosomal protein L32 | -0.0242125 |
| ATF3 | activating transcription factor 3 | -0.0241756 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 | -0.0239535 |
| INTS6 | integrator complex subunit 6 | -0.0237951 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | -0.0236977 |
| CMIP | c-Maf inducing protein | -0.0234681 |
| FABP1 | fatty acid binding protein 1, liver | -0.0234504 |
| APOE | apolipoprotein E | -0.0225576 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0221238 |
| RPS19 | ribosomal protein S19 | -0.0218778 |
| RACK1 | receptor for activated C kinase 1 | -0.0215404 |
| RPL10A | ribosomal protein L10a | -0.0210863 |
| TFRC | transferrin receptor | -0.0210515 |
| RRBP1 | ribosome binding protein 1 | -0.0210089 |
| APOA1 | apolipoprotein A-I | -0.0206094 |
| SQSTM1 | sequestosome 1 | -0.0204755 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0204602 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | -0.0202522 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.0200127 |
| RPLP2 | ribosomal protein, large, P2 | -0.0198314 |
| GNAS | GNAS complex locus | -0.0197693 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0197024 |
| STK17A | serine/threonine kinase 17a | -0.0195371 |
| KRT23 | keratin 23, type I | -0.0188909 |
| NPR2 | natriuretic peptide receptor 2 | -0.0185689 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0185577 |
| SRPK1 | SRSF protein kinase 1 | -0.0184161 |
| DNAH5 | dynein, axonemal, heavy chain 5 | -0.0181864 |
| CANX | calnexin | -0.0181182 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0180627 |
| LMCD1 | LIM and cysteine-rich domains 1 | -0.0180417 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0177823 |
| DNAH17 | dynein, axonemal, heavy chain 17 | -0.0174275 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0172551 |
| RPLP1 | ribosomal protein, large, P1 | -0.0172067 |
| RAPGEF5 | Rap guanine nucleotide exchange factor (GEF) 5 | -0.0171877 |
| PLXDC2 | plexin domain containing 2 | -0.0170616 |
| ATF6 | activating transcription factor 6 | -0.0170364 |
| DUSP6 | dual specificity phosphatase 6 | -0.0169789 |
| RPS16 | ribosomal protein S16 | -0.0169584 |
| SEC24D | SEC24 family member D | -0.016549 |
| SYNE1 | spectrin repeat containing, nuclear envelope 1 | -0.0164716 |
| JUN | jun proto-oncogene | -0.0163838 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0163457 |
| PNPLA8 | patatin-like phospholipase domain containing 8 | -0.0161387 |
| GOLGB1 | golgin B1 | -0.0161357 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0159527 |
| FAM162A | family with sequence similarity 162, member A | -0.0159337 |
| CD2AP | CD2-associated protein | -0.015894 |
| UGDH | UDP-glucose 6-dehydrogenase | -0.01574 |
| SYN3 | synapsin III | -0.0157142 |
| TMSB10 | thymosin beta 10 | -0.0155679 |
| RPL28 | ribosomal protein L28 | -0.0154131 |
| MORF4L2 | mortality factor 4 like 2 | -0.0153121 |
| TXNRD1 | thioredoxin reductase 1 | -0.0152114 |
| BMERB1 | bMERB domain containing 1 | -0.015201 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0151978 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0151906 |
| RPL34 | ribosomal protein L34 | -0.0151354 |
| RPS25 | ribosomal protein S25 | -0.0150491 |
| RPS10 | ribosomal protein S10 | -0.0149173 |
| AEBP2 | AE binding protein 2 | -0.0148508 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0147548 |
| EEF1B2 | eukaryotic translation elongation factor 1 beta 2 | -0.0146343 |
| TCERG1 | transcription elongation regulator 1 | -0.0145906 |
| ABAT | 4-aminobutyrate aminotransferase | -0.0145046 |
| RAI14 | retinoic acid induced 14 | -0.0144316 |
| SRP54 | signal recognition particle 54kDa | -0.014393 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.014379 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | -0.0140406 |
| RBBP6 | retinoblastoma binding protein 6 | -0.0139776 |
| XBP1 | X-box binding protein 1 | -0.0138032 |
