| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | L-Eflornithine (monohydrochloride) perturbation in J82 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the L-Eflornithine (monohydrochloride)_J82 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.320695 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.166479 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.163486 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.148418 |
| CALR | calreticulin | 0.110199 |
| FLNB | filamin B, beta | 0.107768 |
| MT1X | metallothionein 1X | 0.0986041 |
| CD44 | CD44 molecule (Indian blood group) | 0.0948301 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.088743 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0866416 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0860276 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0839328 |
| ATP13A3 | ATPase type 13A3 | 0.0806389 |
| UBC | ubiquitin C | 0.0805516 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0782196 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0773465 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0745337 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0719381 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0690819 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.068306 |
| CANX | calnexin | 0.0682598 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0665315 |
| ENO1 | enolase 1, (alpha) | 0.0661516 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0632603 |
| VEGFA | vascular endothelial growth factor A | 0.0622637 |
| ERBIN | erbb2 interacting protein | 0.0615138 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0611148 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.060579 |
| HLA-A | major histocompatibility complex, class I, A | 0.0566197 |
| PGK1 | phosphoglycerate kinase 1 | 0.0501336 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0491285 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0474398 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.046529 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0451913 |
| LDHA | lactate dehydrogenase A | 0.0444523 |
| ARF4 | ADP-ribosylation factor 4 | 0.0439621 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0426227 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0414205 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0407969 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | 0.0390809 |
| OGA | O-GlcNAcase | 0.0389483 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0389049 |
| SLC12A8 | solute carrier family 12, member 8 | 0.0387964 |
| TMEM41B | transmembrane protein 41B | 0.0384782 |
| DENND5A | DENN/MADD domain containing 5A | 0.0376635 |
| CALU | calumenin | 0.0374484 |
| MMP12 | matrix metallopeptidase 12 | 0.0372986 |
| SDC4 | syndecan 4 | 0.0370367 |
| NUP98 | nucleoporin 98kDa | 0.0370058 |
| STK4 | serine/threonine kinase 4 | 0.0360827 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0357521 |
| COL5A1 | collagen, type V, alpha 1 | 0.0351393 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0343014 |
| GOLGA4 | golgin A4 | 0.0337162 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0336431 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0335379 |
| AHNAK | AHNAK nucleoprotein | 0.0334642 |
| RASA2 | RAS p21 protein activator 2 | 0.0332395 |
| PLK2 | polo-like kinase 2 | 0.0331493 |
| TMEM165 | transmembrane protein 165 | 0.0330081 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0329625 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0326354 |
| COL7A1 | collagen, type VII, alpha 1 | 0.032389 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.0323875 |
| EGFR | epidermal growth factor receptor | 0.0323278 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0322221 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0317009 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0316631 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0316197 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0313384 |
| STARD13 | StAR-related lipid transfer (START) domain containing 13 | 0.0306189 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0306127 |
| TGFB2 | transforming growth factor, beta 2 | 0.0306043 |
| FNIP1 | folliculin interacting protein 1 | 0.0303942 |
| SETX | senataxin | 0.0303422 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0303332 |
| IL1RAP | interleukin 1 receptor accessory protein | 0.0303055 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0298475 |
| VMP1 | vacuole membrane protein 1 | 0.0297986 |
| TUBB | tubulin, beta class I | 0.0294199 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.028849 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.028769 |
| COPA | coatomer protein complex, subunit alpha | 0.0286272 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0283952 |
| NGLY1 | N-glycanase 1 | 0.0283287 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0282723 |
| CUL4B | cullin 4B | 0.0280173 |
| CTTN | cortactin | 0.0273894 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0267147 |
| CD46 | CD46 molecule, complement regulatory protein | 0.026429 |
| COG5 | component of oligomeric golgi complex 5 | 0.0263109 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | 0.0260048 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0257538 |
| GNAI3 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 | 0.0256809 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | 0.0256648 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0256215 |
| CORO1C | coronin, actin binding protein, 1C | 0.0254097 |
| XPO6 | exportin 6 | 0.0254022 |
| SFTPA2 | surfactant protein A2 | 0.0253914 |
| ACTN4 | actinin, alpha 4 | 0.025329 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FTL | ferritin, light polypeptide | -0.0934232 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0920756 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0903315 |
| TXNRD1 | thioredoxin reductase 1 | -0.0728861 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0726511 |
| RPS6 | ribosomal protein S6 | -0.0636144 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0558842 |
| HLA-B | major histocompatibility complex, class I, B | -0.0552193 |
| RPL35A | ribosomal protein L35a | -0.0535114 |
| CAVIN1 | caveolae associated protein 1 | -0.0429912 |
| DEK | DEK proto-oncogene | -0.0426194 |
| CCND1 | cyclin D1 | -0.0400838 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | -0.0390048 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0368483 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0367092 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0364446 |
| RPS8 | ribosomal protein S8 | -0.0356645 |
| MAP1B | microtubule-associated protein 1B | -0.0355369 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0353917 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0349363 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0343191 |
| RPL30 | ribosomal protein L30 | -0.0336475 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0333496 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0329603 |
| SQSTM1 | sequestosome 1 | -0.0328629 |
| RPS2 | ribosomal protein S2 | -0.032123 |
| ASPH | aspartate beta-hydroxylase | -0.0318039 |
| RPS21 | ribosomal protein S21 | -0.0315606 |
| RPL11 | ribosomal protein L11 | -0.0310925 |
| RPL37A | ribosomal protein L37a | -0.0302597 |
| UBQLN1 | ubiquilin 1 | -0.0298695 |
| RPLP1 | ribosomal protein, large, P1 | -0.0296154 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0295728 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0294228 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0291776 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0290372 |
| GNAS | GNAS complex locus | -0.0285395 |
| LMNA | lamin A/C | -0.0283225 |
| PARD3B | par-3 family cell polarity regulator beta | -0.0282231 |
| HMGB1 | high mobility group box 1 | -0.0281085 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0279719 |
| SPIDR | scaffolding protein involved in DNA repair | -0.027908 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0278758 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0277787 |
| SMYD3 | SET and MYND domain containing 3 | -0.0276181 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0268986 |
| RPL19 | ribosomal protein L19 | -0.0267413 |
| NDRG1 | N-myc downstream regulated 1 | -0.0267103 |
| RPL38 | ribosomal protein L38 | -0.0260464 |
| ZFR | zinc finger RNA binding protein | -0.0248597 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0248349 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | -0.0244576 |
| ZNF804A | zinc finger protein 804A | -0.0244017 |
| RPL9 | ribosomal protein L9 | -0.0242146 |
| CDK6 | cyclin-dependent kinase 6 | -0.0237899 |
| PTMA | prothymosin, alpha | -0.0236526 |
| MKI67 | marker of proliferation Ki-67 | -0.0235957 |
| UBB | ubiquitin B | -0.0235552 |
| KRT7 | keratin 7, type II | -0.0231562 |
| LDHB | lactate dehydrogenase B | -0.023114 |
| HMGA1 | high mobility group AT-hook 1 | -0.0229737 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0229141 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0227334 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0225168 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0224895 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 | -0.0220465 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.022022 |
| GNAI2 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 | -0.0219264 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0218832 |
| TMEM178B | transmembrane protein 178B | -0.0218348 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0217284 |
| PLSCR1 | phospholipid scramblase 1 | -0.0216845 |
| RPL32 | ribosomal protein L32 | -0.0216409 |
| FLNA | filamin A, alpha | -0.021585 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.021512 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0213493 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | -0.0212788 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | -0.0212611 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0212335 |
| RPS20 | ribosomal protein S20 | -0.0211803 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide | -0.0211573 |
| RPL35 | ribosomal protein L35 | -0.0210817 |
| SLC25A5 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | -0.021025 |
| PLCB4 | phospholipase C, beta 4 | -0.0210008 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0209487 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0209412 |
| FOXP1 | forkhead box P1 | -0.0207496 |
| SCLT1 | sodium channel and clathrin linker 1 | -0.0206524 |
| TMSB10 | thymosin beta 10 | -0.0205952 |
| CTR9 | CTR9, Paf1/RNA polymerase II complex component | -0.0205305 |
| RPS29 | ribosomal protein S29 | -0.0204801 |
| NRXN3 | neurexin 3 | -0.0204439 |
| CEP128 | centrosomal protein 128kDa | -0.0203658 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0202943 |
| YBX3 | Y box binding protein 3 | -0.0201027 |
| RPLP2 | ribosomal protein, large, P2 | -0.0200984 |
| CCDC80 | coiled-coil domain containing 80 | -0.0196464 |
| VIM | vimentin | -0.0195326 |
| HSPE1 | heat shock 10kDa protein 1 | -0.0193516 |
| TCEAL4 | transcription elongation factor A (SII)-like 4 | -0.0192376 |
