| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | L-Eflornithine (monohydrochloride) perturbation in LOX-IMVI cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the L-Eflornithine (monohydrochloride)_LOX-IMVI drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.217476 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.112716 |
| ASPH | aspartate beta-hydroxylase | 0.0976065 |
| EFNA5 | ephrin-A5 | 0.0905771 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0843854 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.0812781 |
| MSN | moesin | 0.0810487 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.080998 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0797551 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0790276 |
| LDHA | lactate dehydrogenase A | 0.0738565 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0707781 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0672462 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0668372 |
| MT2A | metallothionein 2A | 0.0655686 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0638775 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.063085 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0612487 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0610365 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0579845 |
| RPL3 | ribosomal protein L3 | 0.0566842 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0545669 |
| UBC | ubiquitin C | 0.0524078 |
| CD109 | CD109 molecule | 0.0520571 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0515554 |
| VCL | vinculin | 0.0511394 |
| RTN4 | reticulon 4 | 0.0503613 |
| PKM | pyruvate kinase, muscle | 0.0502686 |
| FTL | ferritin, light polypeptide | 0.049631 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0490001 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0469559 |
| DTNA | dystrobrevin, alpha | 0.0468786 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0464962 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0462878 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0449251 |
| MCL1 | myeloid cell leukemia 1 | 0.0440948 |
| ENO1 | enolase 1, (alpha) | 0.0435646 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0431279 |
| BRD2 | bromodomain containing 2 | 0.0423352 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0421165 |
| TXNIP | thioredoxin interacting protein | 0.0419801 |
| TPM3 | tropomyosin 3 | 0.0417141 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0412432 |
| ATP13A3 | ATPase type 13A3 | 0.0405929 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0403246 |
| MYOF | myoferlin | 0.0401421 |
| SET | SET nuclear proto-oncogene | 0.0401391 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0394557 |
| VEGFA | vascular endothelial growth factor A | 0.0393582 |
| ANO6 | anoctamin 6 | 0.0392608 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0388266 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.0387286 |
| OGA | O-GlcNAcase | 0.0384544 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0383653 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0371907 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0364208 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0359564 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0356252 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0355855 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0355794 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0353789 |
| SEPTIN7 | septin 7 | 0.0341169 |
| YAP1 | Yes-associated protein 1 | 0.0340423 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0337243 |
| NGLY1 | N-glycanase 1 | 0.0328928 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0326831 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | 0.032139 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0318311 |
| MMP12 | matrix metallopeptidase 12 | 0.0316285 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0315817 |
| PTMA | prothymosin, alpha | 0.0314033 |
| WDR26 | WD repeat domain 26 | 0.0306964 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0306294 |
| USP34 | ubiquitin specific peptidase 34 | 0.0306179 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0305691 |
| RPS18 | ribosomal protein S18 | 0.0301394 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0300295 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | 0.0293989 |
| POTEF | POTE ankyrin domain family, member F | 0.0292728 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0292097 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0291094 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0290758 |
| NEK7 | NIMA-related kinase 7 | 0.0289505 |
| RPL21 | ribosomal protein L21 | 0.0287857 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0285265 |
| MYO6 | myosin VI | 0.0282105 |
| TOP1 | topoisomerase (DNA) I | 0.0280635 |
| FNIP1 | folliculin interacting protein 1 | 0.028057 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0276845 |
| CUL3 | cullin 3 | 0.0276489 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0275905 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0274557 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0274111 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0272998 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0272641 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.027144 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0270635 |
| AXL | AXL receptor tyrosine kinase | 0.027031 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0268356 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.026685 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SAMD3 | sterile alpha motif domain containing 3 | -0.0778202 |
| PTCHD4 | patched domain containing 4 | -0.0685657 |
| TMSB10 | thymosin beta 10 | -0.0678861 |
| NTM | neurotrimin | -0.0615189 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0579574 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.057658 |
| PHACTR1 | phosphatase and actin regulator 1 | -0.0545484 |
| PRKG1 | protein kinase, cGMP-dependent, type I | -0.0538004 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.0517766 |
| ANXA2 | annexin A2 | -0.0513474 |
| VIM | vimentin | -0.039779 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0395089 |
| AHNAK | AHNAK nucleoprotein | -0.0389909 |
| RPS6 | ribosomal protein S6 | -0.0388152 |
| FOXP1 | forkhead box P1 | -0.0385611 |
| ZNF804A | zinc finger protein 804A | -0.0372159 |
| HDAC9 | histone deacetylase 9 | -0.0350164 |
| RPLP1 | ribosomal protein, large, P1 | -0.0349857 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | -0.0336995 |
| GNAS | GNAS complex locus | -0.0331842 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0325721 |
| ACTG1 | actin gamma 1 | -0.0322598 |
| KIAA1217 | KIAA1217 | -0.032004 |
| FMN1 | formin 1 | -0.0311609 |
| RPL11 | ribosomal protein L11 | -0.0310039 |
| INTS6 | integrator complex subunit 6 | -0.0303941 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0288718 |
| CDH13 | cadherin 13 | -0.0286403 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0285993 |
| CDK14 | cyclin-dependent kinase 14 | -0.0281016 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | -0.0278148 |
| BNC2 | basonuclin 2 | -0.0274935 |
| MSR1 | macrophage scavenger receptor 1 | -0.0273204 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.027233 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0272225 |
| AEBP2 | AE binding protein 2 | -0.0269299 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0265387 |
| NABP1 | nucleic acid binding protein 1 | -0.026536 |
| NAV3 | neuron navigator 3 | -0.0263557 |
| KYNU | kynureninase | -0.0263381 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0256728 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.025546 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0254147 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0252788 |
| PCDH11X | protocadherin 11 X-linked | -0.0251926 |
| RPL32 | ribosomal protein L32 | -0.0251743 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0250649 |
| RPS20 | ribosomal protein S20 | -0.0248383 |
| CAVIN1 | caveolae associated protein 1 | -0.0242344 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0236859 |
| RPL36 | ribosomal protein L36 | -0.023339 |
| CDK6 | cyclin-dependent kinase 6 | -0.023189 |
| OR51B5 | olfactory receptor, family 51, subfamily B, member 5 | -0.0226195 |
| WNT2B | wingless-type MMTV integration site family, member 2B | -0.0224519 |
| SYNE1 | spectrin repeat containing, nuclear envelope 1 | -0.0220698 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0218327 |
| RPL35A | ribosomal protein L35a | -0.0217607 |
| NEGR1 | neuronal growth regulator 1 | -0.0215059 |
| ARF1 | ADP-ribosylation factor 1 | -0.0212406 |
| RPLP0 | ribosomal protein, large, P0 | -0.0210245 |
| CFAP299 | cilia and flagella associated protein 299 | -0.0208161 |
| PPP1R10 | protein phosphatase 1, regulatory subunit 10 | -0.0208158 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0207089 |
| MAPKAP1 | mitogen-activated protein kinase associated protein 1 | -0.020674 |
| ETV6 | ets variant 6 | -0.0203341 |
| FBN2 | fibrillin 2 | -0.0194407 |
| PRSS23 | protease, serine, 23 | -0.0188973 |
| PAX3 | paired box 3 | -0.0187273 |
| GPHN | gephyrin | -0.0185942 |
| HS3ST3A1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 | -0.0184691 |
| PTK2 | protein tyrosine kinase 2 | -0.01828 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0182668 |
| DOCK1 | dedicator of cytokinesis 1 | -0.0181088 |
| E2F3 | E2F transcription factor 3 | -0.0178435 |
| BPTF | bromodomain PHD finger transcription factor | -0.0176312 |
| RFX3 | regulatory factor X, 3 (influences HLA class II expression) | -0.0176174 |
| RNF213 | ring finger protein 213 | -0.0175149 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0172502 |
| MAP4 | microtubule-associated protein 4 | -0.0170882 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0170856 |
| NOP58 | NOP58 ribonucleoprotein | -0.0170706 |
| CUX1 | cut-like homeobox 1 | -0.017059 |
| COLEC10 | collectin sub-family member 10 (C-type lectin) | -0.0170382 |
| LRRC23 | leucine rich repeat containing 23 | -0.0167105 |
| PUM3 | pumilio RNA binding family member 3 | -0.0165656 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | -0.0164362 |
| RAD51B | RAD51 paralog B | -0.0164072 |
| GLIS3 | GLIS family zinc finger 3 | -0.0163201 |
| IPO9 | importin 9 | -0.015985 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0159123 |
| RLF | rearranged L-myc fusion | -0.0158424 |
| VOPP1 | vesicular, overexpressed in cancer, prosurvival protein 1 | -0.0157316 |
| TEX14 | testis expressed 14 | -0.0156324 |
| MCPH1 | microcephalin 1 | -0.0156086 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | -0.0156028 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | -0.0155852 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0155781 |
| FLNC | filamin C, gamma | -0.0155036 |
| ADAM32 | ADAM metallopeptidase domain 32 | -0.0154405 |
| PTPRB | protein tyrosine phosphatase, receptor type, B | -0.0153626 |
