| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | L-Eflornithine (monohydrochloride) perturbation in NCI-H1573 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the L-Eflornithine (monohydrochloride)_NCI-H1573 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EGFR | epidermal growth factor receptor | 0.126271 |
| MT2A | metallothionein 2A | 0.0738542 |
| MCL1 | myeloid cell leukemia 1 | 0.0629633 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0609405 |
| UBC | ubiquitin C | 0.0578544 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0570255 |
| LAMA4 | laminin, alpha 4 | 0.056859 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0539341 |
| LAMC2 | laminin, gamma 2 | 0.0490754 |
| GOLGB1 | golgin B1 | 0.0485894 |
| MKI67 | marker of proliferation Ki-67 | 0.0483232 |
| FRY | furry homolog (Drosophila) | 0.0478871 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0464342 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0462812 |
| CES1 | carboxylesterase 1 | 0.0458733 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0407181 |
| BLZF1 | basic leucine zipper nuclear factor 1 | 0.040191 |
| OSMR | oncostatin M receptor | 0.0394127 |
| TOP1 | topoisomerase (DNA) I | 0.0390348 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0388086 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0387758 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0375643 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0360576 |
| PYGL | phosphorylase, glycogen, liver | 0.0355682 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | 0.0353142 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0325403 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | 0.0322669 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0321591 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0302024 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0297099 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0294469 |
| UBR1 | ubiquitin protein ligase E3 component n-recognin 1 | 0.0289656 |
| NGLY1 | N-glycanase 1 | 0.0289449 |
| ZNF638 | zinc finger protein 638 | 0.0281673 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0274144 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0269891 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0263297 |
| GRAMD1B | GRAM domain containing 1B | 0.0261338 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.026075 |
| ATP11A | ATPase, class VI, type 11A | 0.0256804 |
| SENP5 | SUMO1/sentrin specific peptidase 5 | 0.0248793 |
| NPC1 | Niemann-Pick disease, type C1 | 0.0247898 |
| SETX | senataxin | 0.0247863 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | 0.024308 |
| VCL | vinculin | 0.0242192 |
| SEC24D | SEC24 family member D | 0.0237294 |
| TNFAIP8 | tumor necrosis factor, alpha-induced protein 8 | 0.0236919 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0236415 |
| CANX | calnexin | 0.0234053 |
| WDR26 | WD repeat domain 26 | 0.0233272 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0228634 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0227797 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0223015 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0221198 |
| COPA | coatomer protein complex, subunit alpha | 0.0219512 |
| RTN4 | reticulon 4 | 0.0217405 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0217271 |
| SYAP1 | synapse associated protein 1 | 0.0215637 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0215313 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | 0.0215206 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0211524 |
| RAD51B | RAD51 paralog B | 0.0211457 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0210999 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0207732 |
| RNF149 | ring finger protein 149 | 0.0204152 |
| MYO1E | myosin IE | 0.0201957 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0201824 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0199969 |
| MON2 | MON2 homolog (S. cerevisiae) | 0.0199331 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.0197582 |
| SEPTIN2 | septin 2 | 0.0197031 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0194894 |
| GOLGA4 | golgin A4 | 0.0192142 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.0191643 |
| TRAPPC9 | trafficking protein particle complex 9 | 0.0191328 |
| ATXN1 | ataxin 1 | 0.0190331 |
| XRRA1 | X-ray radiation resistance associated 1 | 0.018835 |
| DSPP | dentin sialophosphoprotein | 0.0188115 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | 0.0187704 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0187462 |
| GPATCH2L | G patch domain containing 2-like | 0.0182454 |
| HM13 | histocompatibility (minor) 13 | 0.0181427 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0178892 |
| VMP1 | vacuole membrane protein 1 | 0.0178399 |
| PRELID2 | PRELI domain containing 2 | 0.0178278 |
| SON | SON DNA binding protein | 0.0177566 |
| TMF1 | TATA element modulatory factor 1 | 0.0177542 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0175525 |
| LDHA | lactate dehydrogenase A | 0.0175375 |
| LGALS12 | lectin, galactoside-binding, soluble, 12 | 0.0174772 |
| HDLBP | high density lipoprotein binding protein | 0.0173355 |
| SCFD1 | sec1 family domain containing 1 | 0.0172407 |
| OGA | O-GlcNAcase | 0.0171677 |
| FAAH2 | fatty acid amide hydrolase 2 | 0.0169992 |
| VEZT | vezatin, adherens junctions transmembrane protein | 0.0169267 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | 0.0168368 |
| NSUN6 | NOP2/Sun domain family, member 6 | 0.0167852 |
| ZNF292 | zinc finger protein 292 | 0.0167132 |
| LPCAT2 | lysophosphatidylcholine acyltransferase 2 | 0.016656 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0164675 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.125902 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.114301 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0855114 |
| TXNRD1 | thioredoxin reductase 1 | -0.0816074 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0782776 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0681856 |
| PTMA | prothymosin, alpha | -0.0541549 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.0494552 |
| ANXA2 | annexin A2 | -0.0432859 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0401594 |
| ASPH | aspartate beta-hydroxylase | -0.0398656 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0379354 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0378692 |
| KRT7 | keratin 7, type II | -0.0363773 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0359169 |
| TPD52 | tumor protein D52 | -0.0356131 |
| CCND1 | cyclin D1 | -0.0348525 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0346283 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.033685 |
| RNF213 | ring finger protein 213 | -0.031944 |
| LMO7 | LIM domain 7 | -0.0318007 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0307106 |
| MYOF | myoferlin | -0.030573 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0279093 |
| KCMF1 | potassium channel modulatory factor 1 | -0.0276686 |
| VOPP1 | vesicular, overexpressed in cancer, prosurvival protein 1 | -0.0267257 |
| LRP1B | low density lipoprotein receptor-related protein 1B | -0.0263257 |
| CAV2 | caveolin 2 | -0.026164 |
| NDRG1 | N-myc downstream regulated 1 | -0.0259947 |
| RPL35A | ribosomal protein L35a | -0.0258175 |
| ACTG1 | actin gamma 1 | -0.0257759 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0255837 |
| AHNAK | AHNAK nucleoprotein | -0.0250368 |
| KRT8 | keratin 8, type II | -0.0249813 |
| KRT18 | keratin 18, type I | -0.0248661 |
| SCEL | sciellin | -0.024652 |
| RPL37A | ribosomal protein L37a | -0.0239034 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0238504 |
| PKM | pyruvate kinase, muscle | -0.0238321 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0237767 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0234468 |
| H1-0 | H1.0 linker histone | -0.0218847 |
| FTL | ferritin, light polypeptide | -0.021745 |
| DENND5B | DENN/MADD domain containing 5B | -0.0211874 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0209985 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0207031 |
| AP1S3 | adaptor-related protein complex 1, sigma 3 subunit | -0.0206486 |
| RPS3 | ribosomal protein S3 | -0.0200945 |
| S100A10 | S100 calcium binding protein A10 | -0.0200453 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0198212 |
| SMAD3 | SMAD family member 3 | -0.0197047 |
| FLNB | filamin B, beta | -0.0195385 |
| AHNAK2 | AHNAK nucleoprotein 2 | -0.0189667 |
| PRKCA | protein kinase C, alpha | -0.0186608 |
| TNS3 | tensin 3 | -0.0186539 |
| RPS24 | ribosomal protein S24 | -0.0186001 |
| RPLP1 | ribosomal protein, large, P1 | -0.0183986 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0181707 |
| RAB27B | RAB27B, member RAS oncogene family | -0.0180644 |
| RNF145 | ring finger protein 145 | -0.0172954 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0171691 |
| CST3 | cystatin C | -0.0171086 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0169418 |
| RAB10 | RAB10, member RAS oncogene family | -0.0169156 |
| CHML | choroideremia-like (Rab escort protein 2) | -0.0168567 |
| PCED1B | PC-esterase domain containing 1B | -0.0168316 |
| RPS25 | ribosomal protein S25 | -0.0167594 |
| UVRAG | UV radiation resistance associated | -0.0167328 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0164219 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0161611 |
| B2M | beta-2-microglobulin | -0.0161041 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.0160737 |
| CD163L1 | CD163 molecule-like 1 | -0.0155239 |
| PARD3 | par-3 family cell polarity regulator | -0.0152978 |
| CLOCK | clock circadian regulator | -0.0152599 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0150515 |
| ANKRD37 | ankyrin repeat domain 37 | -0.014806 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0146179 |
| KRT19 | keratin 19, type I | -0.0145088 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0145001 |
| ATG14 | autophagy related 14 | -0.0144749 |
| RPL19 | ribosomal protein L19 | -0.0144281 |
| PGK1 | phosphoglycerate kinase 1 | -0.0143778 |
| RPL34 | ribosomal protein L34 | -0.0143258 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.014285 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0139741 |
| SLMAP | sarcolemma associated protein | -0.0138685 |
| LMNA | lamin A/C | -0.0137953 |
| STC2 | stanniocalcin 2 | -0.0137215 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0136508 |
| RPS14 | ribosomal protein S14 | -0.0134557 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | -0.0133562 |
| S100A6 | S100 calcium binding protein A6 | -0.0133076 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0131423 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | -0.013103 |
| HBP1 | HMG-box transcription factor 1 | -0.0130586 |
| RPL31 | ribosomal protein L31 | -0.0129045 |
| MX1 | MX dynamin-like GTPase 1 | -0.0128899 |
| DSG2 | desmoglein 2 | -0.0128624 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0127656 |
