| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | L-Eflornithine (monohydrochloride) perturbation in NCI-H23 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the L-Eflornithine (monohydrochloride)_NCI-H23 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.326002 |
| YBX3 | Y box binding protein 3 | 0.110642 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.096961 |
| RAD51B | RAD51 paralog B | 0.0947351 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0944582 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0882646 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0713114 |
| VCL | vinculin | 0.0641837 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0612935 |
| MT2A | metallothionein 2A | 0.0564471 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0556797 |
| OSMR | oncostatin M receptor | 0.0480806 |
| EGR1 | early growth response 1 | 0.046349 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.045787 |
| CTTN | cortactin | 0.0442877 |
| EXOC4 | exocyst complex component 4 | 0.0440047 |
| BBX | bobby sox homolog (Drosophila) | 0.0438924 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0424675 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0419935 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0394141 |
| MMP12 | matrix metallopeptidase 12 | 0.0393689 |
| HMGA2 | high mobility group AT-hook 2 | 0.0382615 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0375909 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | 0.0368858 |
| MORF4L2 | mortality factor 4 like 2 | 0.0365491 |
| CCNL1 | cyclin L1 | 0.0365306 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | 0.0365234 |
| AFF3 | AF4/FMR2 family, member 3 | 0.0354544 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0346328 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0342167 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0339165 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0337682 |
| MKI67 | marker of proliferation Ki-67 | 0.0337344 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0335423 |
| KLF6 | Kruppel-like factor 6 | 0.0332262 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | 0.0329237 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0328756 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0328539 |
| PYGL | phosphorylase, glycogen, liver | 0.0327966 |
| FMNL2 | formin-like 2 | 0.0326062 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0325195 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0324448 |
| CALD1 | caldesmon 1 | 0.0317091 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | 0.0316879 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | 0.03141 |
| CUL4B | cullin 4B | 0.0313885 |
| YES1 | YES proto-oncogene 1, Src family tyrosine kinase | 0.0306487 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0306412 |
| TPM4 | tropomyosin 4 | 0.0301703 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0296456 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0291551 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0291115 |
| DENND5B | DENN/MADD domain containing 5B | 0.0286873 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0284798 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.027983 |
| PDE10A | phosphodiesterase 10A | 0.027253 |
| STMN1 | stathmin 1 | 0.0267179 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0265258 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | 0.0265219 |
| ANO6 | anoctamin 6 | 0.0257437 |
| NTSR1 | neurotensin receptor 1 (high affinity) | 0.0255949 |
| DENND1A | DENN/MADD domain containing 1A | 0.0255365 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0253153 |
| EHBP1 | EH domain binding protein 1 | 0.0252849 |
| POTEF | POTE ankyrin domain family, member F | 0.0248516 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0246897 |
| PPM1L | protein phosphatase, Mg2+/Mn2+ dependent, 1L | 0.0246578 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0241746 |
| SENP6 | SUMO1/sentrin specific peptidase 6 | 0.0239171 |
| JMJD1C | jumonji domain containing 1C | 0.0238464 |
| ANKRD36B | ankyrin repeat domain 36B | 0.0238409 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | 0.0237725 |
| NABP1 | nucleic acid binding protein 1 | 0.0236484 |
| ACIN1 | apoptotic chromatin condensation inducer 1 | 0.0236346 |
| SBF2 | SET binding factor 2 | 0.0228192 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0225324 |
| CCDC91 | coiled-coil domain containing 91 | 0.0224512 |
| DSPP | dentin sialophosphoprotein | 0.0223543 |
| ODF2L | outer dense fiber of sperm tails 2-like | 0.0223461 |
| PATJ | PATJ crumbs cell polarity complex component | 0.0222523 |
| MT1X | metallothionein 1X | 0.0222387 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0222168 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0218651 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0216919 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.0216534 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0216058 |
| PLSCR1 | phospholipid scramblase 1 | 0.0214866 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | 0.0214089 |
| CUX1 | cut-like homeobox 1 | 0.0209953 |
| YAP1 | Yes-associated protein 1 | 0.0207889 |
| STXBP3 | syntaxin binding protein 3 | 0.0207623 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | 0.0207379 |
| SNX14 | sorting nexin 14 | 0.0204503 |
| PTK2 | protein tyrosine kinase 2 | 0.0202338 |
| EGFR | epidermal growth factor receptor | 0.0199078 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0198979 |
| XRN1 | 5'-3' exoribonuclease 1 | 0.0198455 |
| CENPF | centromere protein F, 350/400kDa | 0.0198173 |
| VMP1 | vacuole membrane protein 1 | 0.0197056 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0196337 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TFPI2 | tissue factor pathway inhibitor 2 | -0.209261 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.161264 |
| UBC | ubiquitin C | -0.152032 |
| RPS27A | ribosomal protein S27a | -0.143196 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.137389 |
| TMSB10 | thymosin beta 10 | -0.112051 |
| VIM | vimentin | -0.110959 |
| PCBP2 | poly(rC) binding protein 2 | -0.1043 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0864361 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0805879 |
| RPL23 | ribosomal protein L23 | -0.0766325 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0667009 |
| AHNAK | AHNAK nucleoprotein | -0.0653552 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0648286 |
| SFPQ | splicing factor proline/glutamine-rich | -0.0605088 |
| ENO1 | enolase 1, (alpha) | -0.060234 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0548858 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.052388 |
| RPL37A | ribosomal protein L37a | -0.0511699 |
| RPS8 | ribosomal protein S8 | -0.0469817 |
| VCP | valosin containing protein | -0.0452059 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0450127 |
| PKM | pyruvate kinase, muscle | -0.0420632 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0410507 |
| RPS3 | ribosomal protein S3 | -0.0410011 |
| RPL5 | ribosomal protein L5 | -0.0408436 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0400294 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0382866 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0379696 |
| PTMA | prothymosin, alpha | -0.0361834 |
| PREPL | prolyl endopeptidase-like | -0.0354794 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | -0.035257 |
| RPS21 | ribosomal protein S21 | -0.0340695 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.034055 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0328611 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0326594 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | -0.0326571 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0325762 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0321185 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0311776 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0308667 |
| LDHB | lactate dehydrogenase B | -0.0307003 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0295421 |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha | -0.029367 |
| XPO1 | exportin 1 | -0.0289331 |
| NONO | non-POU domain containing, octamer-binding | -0.028659 |
| AHCYL1 | adenosylhomocysteinase-like 1 | -0.0283731 |
| HSPA1A | heat shock 70kDa protein 1A | -0.0280681 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0277879 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0277793 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0273204 |
| RPS29 | ribosomal protein S29 | -0.0272326 |
| RPS12 | ribosomal protein S12 | -0.0272276 |
| TNPO1 | transportin 1 | -0.0262894 |
| RPS10 | ribosomal protein S10 | -0.0259465 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | -0.0258587 |
| MARCHF4 | membrane associated ring-CH-type finger 4 | -0.0253101 |
| IPO7 | importin 7 | -0.0244391 |
| TOP1 | topoisomerase (DNA) I | -0.0244144 |
| WNK1 | WNK lysine deficient protein kinase 1 | -0.0243429 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.024249 |
| ADRM1 | adhesion regulating molecule 1 | -0.0240812 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0240306 |
| ZNF207 | zinc finger protein 207 | -0.0239733 |
| CANX | calnexin | -0.0239589 |
| CALU | calumenin | -0.0239076 |
| PHIP | pleckstrin homology domain interacting protein | -0.0238692 |
| TLN1 | talin 1 | -0.0235518 |
| YBX1 | Y box binding protein 1 | -0.0234554 |
| TPM3 | tropomyosin 3 | -0.0228015 |
| CAVIN1 | caveolae associated protein 1 | -0.0227773 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | -0.0227502 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.0226377 |
| RPS17 | ribosomal protein S17 | -0.0225191 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0224743 |
| TRIP12 | thyroid hormone receptor interactor 12 | -0.0222599 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | -0.0221806 |
| FAM199X | family with sequence similarity 199, X-linked | -0.0221511 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0219298 |
| COG5 | component of oligomeric golgi complex 5 | -0.0215908 |
| CCT4 | chaperonin containing TCP1, subunit 4 (delta) | -0.0209794 |
| RPL9 | ribosomal protein L9 | -0.0208064 |
| RPL15 | ribosomal protein L15 | -0.0206042 |
| VAPA | VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa | -0.0205062 |
| GTPBP4 | GTP binding protein 4 | -0.0204068 |
| CCND1 | cyclin D1 | -0.0203894 |
| RPLP2 | ribosomal protein, large, P2 | -0.0202829 |
| EIF3B | eukaryotic translation initiation factor 3, subunit B | -0.0202536 |
| ZNF638 | zinc finger protein 638 | -0.0199674 |
| XPOT | exportin, tRNA | -0.01996 |
| RPS15 | ribosomal protein S15 | -0.0197801 |
| CCND2 | cyclin D2 | -0.0197052 |
| CDK12 | cyclin-dependent kinase 12 | -0.0196303 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0195749 |
| JUN | jun proto-oncogene | -0.0195543 |
| KHSRP | KH-type splicing regulatory protein | -0.0195415 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0195053 |
| RPL26 | ribosomal protein L26 | -0.0193793 |
| CCT5 | chaperonin containing TCP1, subunit 5 (epsilon) | -0.0193025 |
| SRPK2 | SRSF protein kinase 2 | -0.0192485 |
