| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | L-Eflornithine (monohydrochloride) perturbation in NCI-H460 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the L-Eflornithine (monohydrochloride)_NCI-H460 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ASPH | aspartate beta-hydroxylase | 0.191087 |
| EFNA5 | ephrin-A5 | 0.185561 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.154734 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.128529 |
| MYOF | myoferlin | 0.125613 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.114359 |
| GDA | guanine deaminase | 0.103461 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.101016 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.100267 |
| PM20D1 | peptidase M20 domain containing 1 | 0.0988347 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0977445 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0939798 |
| GRAMD1B | GRAM domain containing 1B | 0.087618 |
| TXNRD1 | thioredoxin reductase 1 | 0.0866139 |
| KYNU | kynureninase | 0.0849318 |
| COL5A2 | collagen, type V, alpha 2 | 0.0815198 |
| DST | dystonin | 0.079081 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0788038 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0787711 |
| NEK7 | NIMA-related kinase 7 | 0.0764835 |
| NRCAM | neuronal cell adhesion molecule | 0.0755666 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0709651 |
| COL8A1 | collagen, type VIII, alpha 1 | 0.0707764 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0697655 |
| EPB41L3 | erythrocyte membrane protein band 4.1-like 3 | 0.0671888 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0670659 |
| PDE10A | phosphodiesterase 10A | 0.0663162 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0655872 |
| CANX | calnexin | 0.0645241 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0644 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.06088 |
| NPAS2 | neuronal PAS domain protein 2 | 0.060065 |
| CTSC | cathepsin C | 0.0590294 |
| CENPF | centromere protein F, 350/400kDa | 0.0583426 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.058184 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0559199 |
| MKI67 | marker of proliferation Ki-67 | 0.05584 |
| MCL1 | myeloid cell leukemia 1 | 0.0558197 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0557889 |
| TGFBR1 | transforming growth factor, beta receptor 1 | 0.0554408 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0553158 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.054951 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0548244 |
| SLC39A8 | solute carrier family 39 (zinc transporter), member 8 | 0.0537354 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0520819 |
| CD109 | CD109 molecule | 0.0518839 |
| LDHA | lactate dehydrogenase A | 0.0516087 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0515703 |
| MFF | mitochondrial fission factor | 0.0513288 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0512068 |
| UBC | ubiquitin C | 0.0502406 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0501357 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0491482 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0488221 |
| PGK1 | phosphoglycerate kinase 1 | 0.0485452 |
| ENO1 | enolase 1, (alpha) | 0.0477966 |
| OGA | O-GlcNAcase | 0.0471028 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.04652 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0455203 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0450773 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0447724 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0442056 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0440842 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0439533 |
| RTN4 | reticulon 4 | 0.0435596 |
| PCBP3 | poly(rC) binding protein 3 | 0.0430452 |
| TMX4 | thioredoxin-related transmembrane protein 4 | 0.0423629 |
| RGS2 | regulator of G-protein signaling 2 | 0.0419837 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.041982 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0418295 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0414029 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.0402475 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | 0.0402095 |
| FLNB | filamin B, beta | 0.0395204 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | 0.0389228 |
| PTGR1 | prostaglandin reductase 1 | 0.0388582 |
| RAB3B | RAB3B, member RAS oncogene family | 0.0378925 |
| PDGFA | platelet-derived growth factor alpha polypeptide | 0.0377829 |
| TNPO1 | transportin 1 | 0.037638 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.0372244 |
| COL4A6 | collagen, type IV, alpha 6 | 0.0360602 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0358486 |
| COL4A5 | collagen, type IV, alpha 5 | 0.0358284 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0353203 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.0349692 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0349631 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0344093 |
| ENAH | enabled homolog (Drosophila) | 0.0340859 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0337898 |
| PTEN | phosphatase and tensin homolog | 0.0335917 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0335523 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0334783 |
| CUL4B | cullin 4B | 0.0332797 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0332695 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0332693 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0331325 |
| ZNF292 | zinc finger protein 292 | 0.0330702 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0330149 |
| EZR | ezrin | 0.0328261 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0325676 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.117649 |
| DPP10 | dipeptidyl-peptidase 10 (non-functional) | -0.0768086 |
| CDH13 | cadherin 13 | -0.0666927 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0581239 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0558356 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0437543 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0333822 |
| RPL35A | ribosomal protein L35a | -0.0320905 |
| LSAMP | limbic system-associated membrane protein | -0.0318427 |
| AUTS2 | autism susceptibility candidate 2 | -0.0305378 |
| ADGRD1 | adhesion G protein-coupled receptor D1 | -0.0293192 |
| RPL37A | ribosomal protein L37a | -0.0259755 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0257104 |
| CADM2 | cell adhesion molecule 2 | -0.0236552 |
| TMSB10 | thymosin beta 10 | -0.0235213 |
| NCKAP5 | NCK-associated protein 5 | -0.0228808 |
| HLA-B | major histocompatibility complex, class I, B | -0.0227218 |
| SOX6 | SRY (sex determining region Y)-box 6 | -0.022582 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0223089 |
| PCDH9 | protocadherin 9 | -0.0220156 |
| XYLT1 | xylosyltransferase I | -0.0218301 |
| ADARB2 | adenosine deaminase, RNA-specific, B2 (non-functional) | -0.0216658 |
| DHRSX | dehydrogenase/reductase (SDR family) X-linked | -0.0214668 |
| RPS21 | ribosomal protein S21 | -0.0205286 |
| RPS6 | ribosomal protein S6 | -0.0203994 |
| RPS19 | ribosomal protein S19 | -0.0181963 |
| FSTL4 | follistatin-like 4 | -0.0177732 |
| RPLP1 | ribosomal protein, large, P1 | -0.017762 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.017568 |
| RPL34 | ribosomal protein L34 | -0.0171155 |
| AEBP2 | AE binding protein 2 | -0.0169325 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | -0.0169292 |
| UNC5D | unc-5 homolog D (C. elegans) | -0.0160004 |
| VIM | vimentin | -0.0156383 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0153244 |
| RPS24 | ribosomal protein S24 | -0.0151187 |
| TENM3 | teneurin transmembrane protein 3 | -0.0148075 |
| CUX1 | cut-like homeobox 1 | -0.0146985 |
| RPS28 | ribosomal protein S28 | -0.0146517 |
| RPS25 | ribosomal protein S25 | -0.0145419 |
| TENM2 | teneurin transmembrane protein 2 | -0.0145332 |
| PCDH15 | protocadherin-related 15 | -0.0137087 |
| CTNND2 | catenin (cadherin-associated protein), delta 2 | -0.0135962 |
| RPS10 | ribosomal protein S10 | -0.013376 |
| SQSTM1 | sequestosome 1 | -0.0133484 |
| PDE1C | phosphodiesterase 1C, calmodulin-dependent 70kDa | -0.0132887 |
| LAMA5 | laminin, alpha 5 | -0.0128384 |
| SLCO1C1 | solute carrier organic anion transporter family, member 1C1 | -0.0125783 |
| DENND1A | DENN/MADD domain containing 1A | -0.0125017 |
| RPS23 | ribosomal protein S23 | -0.0122883 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.012036 |
| RANBP17 | RAN binding protein 17 | -0.0119802 |
| RPL31 | ribosomal protein L31 | -0.011978 |
| RPS16 | ribosomal protein S16 | -0.0119513 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0119362 |
| RPL38 | ribosomal protein L38 | -0.0116844 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0116112 |
| P3H2 | prolyl 3-hydroxylase 2 | -0.0115046 |
| OGDH | oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) | -0.0114278 |
| SVIL | supervillin | -0.011315 |
| PRSS23 | protease, serine, 23 | -0.0112517 |
| RPS8 | ribosomal protein S8 | -0.0112204 |
| SUMF1 | sulfatase modifying factor 1 | -0.0111711 |
| C9ORF153 | chromosome 9 open reading frame 153 | -0.0110858 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | -0.011079 |
| LAMB4 | laminin, beta 4 | -0.0110402 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0107955 |
| PCDH7 | protocadherin 7 | -0.0107445 |
| TMEM178B | transmembrane protein 178B | -0.0106603 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.010588 |
| AADAC | arylacetamide deacetylase | -0.0104583 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0104214 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0102156 |
| RPS13 | ribosomal protein S13 | -0.00991216 |
| RPL9 | ribosomal protein L9 | -0.00984027 |
| RAD51B | RAD51 paralog B | -0.00960977 |
| RPS17 | ribosomal protein S17 | -0.00952168 |
| RPS12 | ribosomal protein S12 | -0.00945781 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | -0.00944887 |
| RPL36A | ribosomal protein L36a | -0.00943597 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.00943389 |
| ADGRG1 | adhesion G protein-coupled receptor G1 | -0.00933875 |
| HMGA2 | high mobility group AT-hook 2 | -0.00919844 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.00909507 |
| ASTN2 | astrotactin 2 | -0.00908756 |
| RAB31 | RAB31, member RAS oncogene family | -0.00907346 |
| MAF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog | -0.00905666 |
| WNT2B | wingless-type MMTV integration site family, member 2B | -0.00902431 |
| CLMP | CXADR-like membrane protein | -0.00890533 |
| LMNA | lamin A/C | -0.00889964 |
| RBM47 | RNA binding motif protein 47 | -0.00887242 |
| STEAP1B | STEAP family member 1B | -0.00878549 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | -0.00877539 |
| IGFBP6 | insulin-like growth factor binding protein 6 | -0.00874516 |
| KCNE4 | potassium channel, voltage gated subfamily E regulatory beta subunit 4 | -0.00870704 |
| OBSCN | obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF | -0.00863368 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | -0.00860089 |
| KIAA0825 | KIAA0825 | -0.00855518 |
| SEMA3D | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D | -0.00852032 |
| FOXK1 | forkhead box K1 | -0.00847579 |
