| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | L-Eflornithine (monohydrochloride) perturbation in NCI-H596 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the L-Eflornithine (monohydrochloride)_NCI-H596 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TRIO | trio Rho guanine nucleotide exchange factor | 0.123382 |
| SPAG9 | sperm associated antigen 9 | 0.112534 |
| PGK1 | phosphoglycerate kinase 1 | 0.106975 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.103678 |
| FN1 | fibronectin 1 | 0.102319 |
| USP34 | ubiquitin specific peptidase 34 | 0.0984453 |
| WDR45B | WD repeat domain 45B | 0.0869256 |
| DST | dystonin | 0.0863094 |
| ENO1 | enolase 1, (alpha) | 0.0811104 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0799628 |
| LDHA | lactate dehydrogenase A | 0.0785877 |
| STC1 | stanniocalcin 1 | 0.0755496 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0693986 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0690084 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0681999 |
| COPA | coatomer protein complex, subunit alpha | 0.0657776 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0655166 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0648584 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0616808 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0592594 |
| ASPH | aspartate beta-hydroxylase | 0.0580896 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0533611 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0532837 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0531306 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0530836 |
| RBM39 | RNA binding motif protein 39 | 0.0505815 |
| RPL11 | ribosomal protein L11 | 0.0491279 |
| FMNL2 | formin-like 2 | 0.0477005 |
| VMP1 | vacuole membrane protein 1 | 0.0470602 |
| RPS12 | ribosomal protein S12 | 0.0459876 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0456148 |
| ATP13A3 | ATPase type 13A3 | 0.0451348 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0439365 |
| NDRG1 | N-myc downstream regulated 1 | 0.0427205 |
| RACK1 | receptor for activated C kinase 1 | 0.0423312 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0418484 |
| SRPK2 | SRSF protein kinase 2 | 0.0407496 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0402261 |
| GLG1 | golgi glycoprotein 1 | 0.0398258 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0391048 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0389944 |
| ANO6 | anoctamin 6 | 0.0386735 |
| PKM | pyruvate kinase, muscle | 0.0375922 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0367804 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0349572 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0346224 |
| MT2A | metallothionein 2A | 0.0342591 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0339192 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0337862 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0329652 |
| IGF2 | insulin-like growth factor 2 | 0.0327527 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.03228 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0310665 |
| NAP1L4 | nucleosome assembly protein 1-like 4 | 0.0309568 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0305309 |
| MYOF | myoferlin | 0.0303131 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0301575 |
| MATR3 | matrin 3 | 0.0290702 |
| RORA | RAR-related orphan receptor A | 0.0284598 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | 0.0280788 |
| RPS16 | ribosomal protein S16 | 0.0278244 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0274522 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0273149 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0270251 |
| COL5A2 | collagen, type V, alpha 2 | 0.0265573 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0265003 |
| ZNF292 | zinc finger protein 292 | 0.0257335 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 0.0255243 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0255136 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0238331 |
| BBX | bobby sox homolog (Drosophila) | 0.0232784 |
| RPS3 | ribosomal protein S3 | 0.0229169 |
| RTN4 | reticulon 4 | 0.0227431 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0224951 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0219615 |
| PHF3 | PHD finger protein 3 | 0.0210025 |
| CD44 | CD44 molecule (Indian blood group) | 0.0207254 |
| RPLP1 | ribosomal protein, large, P1 | 0.0198551 |
| TXNRD1 | thioredoxin reductase 1 | 0.019415 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0186084 |
| CALR | calreticulin | 0.0181858 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0178359 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0177519 |
| NUCB2 | nucleobindin 2 | 0.0173855 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0169372 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.0166934 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0160056 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0145672 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.0143174 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.0143109 |
| PDE10A | phosphodiesterase 10A | 0.0119734 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0105158 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0104876 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.00992066 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.00988286 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.00946139 |
| TPR | translocated promoter region, nuclear basket protein | 0.00941143 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.00929898 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.00912908 |
| FBL | fibrillarin | 0.00903752 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.127904 |
| CANX | calnexin | -0.101762 |
| HMGA2 | high mobility group AT-hook 2 | -0.0998333 |
| RAD51B | RAD51 paralog B | -0.0904459 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0762554 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.075437 |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 | -0.0752233 |
| FHIT | fragile histidine triad | -0.0742698 |
| LAMA4 | laminin, alpha 4 | -0.0721627 |
| EFNA5 | ephrin-A5 | -0.070048 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0696523 |
| BAZ2B | bromodomain adjacent to zinc finger domain, 2B | -0.0694759 |
| EGR1 | early growth response 1 | -0.069361 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0692354 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0664605 |
| ATP11A | ATPase, class VI, type 11A | -0.0645939 |
| ZNF608 | zinc finger protein 608 | -0.0644967 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0638742 |
| PRKCA | protein kinase C, alpha | -0.0635571 |
| PEG10 | paternally expressed 10 | -0.0618792 |
| TMSB10 | thymosin beta 10 | -0.0610331 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0586708 |
| MED13 | mediator complex subunit 13 | -0.0585803 |
| CHD9 | chromodomain helicase DNA binding protein 9 | -0.0578426 |
| EGFR | epidermal growth factor receptor | -0.0577428 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0569653 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0548124 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0539179 |
| RPL37 | ribosomal protein L37 | -0.0531966 |
| RPS19 | ribosomal protein S19 | -0.0530501 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0524731 |
| LAMC2 | laminin, gamma 2 | -0.0521831 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0520173 |
| MYO1E | myosin IE | -0.0497716 |
| VIM | vimentin | -0.0495564 |
| RNF213 | ring finger protein 213 | -0.0483086 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0481187 |
| TUT7 | terminal uridylyl transferase 7 | -0.0472768 |
| SPG11 | spastic paraplegia 11 (autosomal recessive) | -0.0460659 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0458285 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0455483 |
| FTL | ferritin, light polypeptide | -0.0452916 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0445904 |
| PARD3 | par-3 family cell polarity regulator | -0.0444793 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0443066 |
| EXOC4 | exocyst complex component 4 | -0.0442678 |
| PDE8A | phosphodiesterase 8A | -0.0432416 |
| RPS13 | ribosomal protein S13 | -0.0429834 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.041215 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0409028 |
| GOLGB1 | golgin B1 | -0.0391463 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0384342 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0375306 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0370594 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0370192 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0366592 |
| CDK13 | cyclin-dependent kinase 13 | -0.0364556 |
| ATXN1 | ataxin 1 | -0.0348851 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | -0.0346517 |
| PRPF38B | pre-mRNA processing factor 38B | -0.0346372 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | -0.0344501 |
| LMO7 | LIM domain 7 | -0.034252 |
| S100A10 | S100 calcium binding protein A10 | -0.0340169 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0335612 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0334725 |
| CCNI | cyclin I | -0.0331472 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0324205 |
| RPS8 | ribosomal protein S8 | -0.0323529 |
| CDH13 | cadherin 13 | -0.0320911 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0320209 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0316431 |
| RPL15 | ribosomal protein L15 | -0.0315911 |
| RPL35A | ribosomal protein L35a | -0.0309767 |
| OGA | O-GlcNAcase | -0.0305205 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.0301305 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | -0.0301235 |
| DNER | delta/notch-like EGF repeat containing | -0.029951 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0297292 |
| SGIP1 | SH3-domain GRB2-like (endophilin) interacting protein 1 | -0.0292844 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0284846 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0284627 |
| RRBP1 | ribosome binding protein 1 | -0.0259448 |
| RPL31 | ribosomal protein L31 | -0.0258849 |
| ACTG1 | actin gamma 1 | -0.025789 |
| SLTM | SAFB-like, transcription modulator | -0.0247936 |
| HOOK2 | hook microtubule-tethering protein 2 | -0.024535 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0242734 |
| ATF6 | activating transcription factor 6 | -0.0233064 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0226765 |
| ANXA2 | annexin A2 | -0.0225147 |
| RABGAP1 | RAB GTPase activating protein 1 | -0.0224205 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | -0.0217041 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.0213554 |
| FAM13A | family with sequence similarity 13, member A | -0.0210078 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.020361 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0202764 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0200013 |
| MED13L | mediator complex subunit 13-like | -0.0196364 |
| RSF1 | remodeling and spacing factor 1 | -0.0189986 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0186776 |
