| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | L-Eflornithine (monohydrochloride) perturbation in PANC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the L-Eflornithine (monohydrochloride)_PANC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.46963 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.203151 |
| VIM | vimentin | 0.191127 |
| VCL | vinculin | 0.169037 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.145803 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.112125 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0959569 |
| UBC | ubiquitin C | 0.0685933 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0616829 |
| FBL | fibrillarin | 0.0581738 |
| SFTPA2 | surfactant protein A2 | 0.0554507 |
| AHNAK | AHNAK nucleoprotein | 0.0517275 |
| ACTN4 | actinin, alpha 4 | 0.0476118 |
| MCL1 | myeloid cell leukemia 1 | 0.0472953 |
| SEPTIN9 | septin 9 | 0.0455982 |
| TMEM41B | transmembrane protein 41B | 0.0424546 |
| EGR1 | early growth response 1 | 0.0407834 |
| ENO1 | enolase 1, (alpha) | 0.0405455 |
| CANX | calnexin | 0.0396418 |
| VMP1 | vacuole membrane protein 1 | 0.0383854 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0377669 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0374668 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0363322 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.035632 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0340994 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | 0.0330206 |
| VEGFA | vascular endothelial growth factor A | 0.0329462 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.032757 |
| SLC38A2 | solute carrier family 38, member 2 | 0.029973 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0298361 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0296637 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | 0.029308 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0292887 |
| OGA | O-GlcNAcase | 0.0291855 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0290739 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0289499 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0281226 |
| TPM1 | tropomyosin 1 (alpha) | 0.0269376 |
| ANGPTL4 | angiopoietin-like 4 | 0.0266356 |
| MYOF | myoferlin | 0.0265904 |
| PLEKHG2 | pleckstrin homology domain containing, family G (with RhoGef domain) member 2 | 0.0263469 |
| PGK1 | phosphoglycerate kinase 1 | 0.0262852 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0262837 |
| H1-0 | H1.0 linker histone | 0.0261597 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0255161 |
| PAF1 | Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae) | 0.0252695 |
| RPL3 | ribosomal protein L3 | 0.0251807 |
| ACTG1 | actin gamma 1 | 0.0250011 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0247172 |
| S100A6 | S100 calcium binding protein A6 | 0.0246618 |
| LDHA | lactate dehydrogenase A | 0.0237852 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0232579 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0230945 |
| RSL1D1 | ribosomal L1 domain containing 1 | 0.0227184 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.0226246 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0219339 |
| CALR | calreticulin | 0.0218782 |
| RTN4 | reticulon 4 | 0.0217212 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0214995 |
| INSIG1 | insulin induced gene 1 | 0.0213461 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0211368 |
| RAP1B | RAP1B, member of RAS oncogene family | 0.020344 |
| APP | amyloid beta (A4) precursor protein | 0.02028 |
| MARS1 | methionyl-tRNA synthetase 1 | 0.0201013 |
| RPL4 | ribosomal protein L4 | 0.0183645 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0182994 |
| FDPS | farnesyl diphosphate synthase | 0.018156 |
| MSN | moesin | 0.0181424 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0181361 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0179935 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0179934 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.017921 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | 0.0179073 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0174836 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0168334 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0166857 |
| CALCOCO2 | calcium binding and coiled-coil domain 2 | 0.0166587 |
| MAP2K1 | mitogen-activated protein kinase kinase 1 | 0.0163792 |
| HLA-A | major histocompatibility complex, class I, A | 0.0163299 |
| HLA-B | major histocompatibility complex, class I, B | 0.0163209 |
| KLF6 | Kruppel-like factor 6 | 0.0162289 |
| SEPTIN10 | septin 10 | 0.0162263 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.016127 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.015806 |
| RSU1 | Ras suppressor protein 1 | 0.0157557 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0155841 |
| ECH1 | enoyl CoA hydratase 1, peroxisomal | 0.0152586 |
| CTTN | cortactin | 0.0152123 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | 0.0151336 |
| XRCC5 | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) | 0.0150789 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0150441 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0149983 |
| POTEF | POTE ankyrin domain family, member F | 0.0149507 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | 0.0149451 |
| IER3 | immediate early response 3 | 0.0147151 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | 0.0146738 |
| EIF3D | eukaryotic translation initiation factor 3, subunit D | 0.0146685 |
| CD44 | CD44 molecule (Indian blood group) | 0.0145557 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | 0.0145048 |
| CTSD | cathepsin D | 0.014319 |
| Symbol | Name | Standardized Value |
|---|---|---|
| RPS16 | ribosomal protein S16 | -0.168063 |
| SAMD4B | sterile alpha motif domain containing 4B | -0.0769428 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0730411 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0657299 |
| RPS2 | ribosomal protein S2 | -0.0654159 |
| SMAD3 | SMAD family member 3 | -0.0582659 |
| RPS12 | ribosomal protein S12 | -0.0477446 |
| TXNRD1 | thioredoxin reductase 1 | -0.0452837 |
| CENPF | centromere protein F, 350/400kDa | -0.043252 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0414945 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0403936 |
| SMYD3 | SET and MYND domain containing 3 | -0.0390854 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0389706 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0386045 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0374824 |
| RPLP2 | ribosomal protein, large, P2 | -0.0372602 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0358578 |
| RPS8 | ribosomal protein S8 | -0.035681 |
| RPL37A | ribosomal protein L37a | -0.0347762 |
| MT2A | metallothionein 2A | -0.0344527 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0344111 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0342845 |
| PTK2 | protein tyrosine kinase 2 | -0.0329707 |
| RPL28 | ribosomal protein L28 | -0.0312144 |
| MED13L | mediator complex subunit 13-like | -0.0309806 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0309105 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0309025 |
| RPL7 | ribosomal protein L7 | -0.0298841 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0296302 |
| ASPH | aspartate beta-hydroxylase | -0.0294676 |
| ANXA2 | annexin A2 | -0.0288484 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0288286 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0283041 |
| CCDC88A | coiled-coil domain containing 88A | -0.0280352 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0275579 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | -0.0274541 |
| ZNF292 | zinc finger protein 292 | -0.0271571 |
| RPS6 | ribosomal protein S6 | -0.0270887 |
| RPL9 | ribosomal protein L9 | -0.0269863 |
| CARD18 | caspase recruitment domain family, member 18 | -0.0267397 |
| RPL11 | ribosomal protein L11 | -0.0266068 |
| JMJD1C | jumonji domain containing 1C | -0.0265537 |
| EFNA5 | ephrin-A5 | -0.0263073 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.026236 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | -0.0254741 |
| SPAG9 | sperm associated antigen 9 | -0.0244079 |
| RPLP1 | ribosomal protein, large, P1 | -0.0238134 |
| RPL12 | ribosomal protein L12 | -0.0233729 |
| LMNA | lamin A/C | -0.0233127 |
| RPS19 | ribosomal protein S19 | -0.0231528 |
| S100A10 | S100 calcium binding protein A10 | -0.0230467 |
| MAPK8 | mitogen-activated protein kinase 8 | -0.0227847 |
| RPS25 | ribosomal protein S25 | -0.0227311 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0226828 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0226128 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0225181 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0225005 |
| SBF2 | SET binding factor 2 | -0.0223173 |
| RPS5 | ribosomal protein S5 | -0.0221722 |
| RPL38 | ribosomal protein L38 | -0.0221089 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | -0.0220301 |
| MORF4L2 | mortality factor 4 like 2 | -0.0218406 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0210588 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.021025 |
| GOLGA4 | golgin A4 | -0.0209151 |
| TFRC | transferrin receptor | -0.0208542 |
| RPS20 | ribosomal protein S20 | -0.0207977 |
| ASXL1 | additional sex combs like transcriptional regulator 1 | -0.0204658 |
| ZC3H12B | zinc finger CCCH-type containing 12B | -0.0204424 |
| NF1 | neurofibromin 1 | -0.02035 |
| GPHN | gephyrin | -0.0201151 |
| PCBP2 | poly(rC) binding protein 2 | -0.0200858 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0199946 |
| ANLN | anillin, actin binding protein | -0.0199561 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.0197097 |
| MTDH | metadherin | -0.0195 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.019419 |
| CDK6 | cyclin-dependent kinase 6 | -0.0191435 |
| GLCCI1 | glucocorticoid induced 1 | -0.0188795 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.0188707 |
| RPS3 | ribosomal protein S3 | -0.0188483 |
| KIF5B | kinesin family member 5B | -0.0187678 |
| PDE3B | phosphodiesterase 3B, cGMP-inhibited | -0.018706 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.018621 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | -0.0184683 |
| ZNF207 | zinc finger protein 207 | -0.0184605 |
| HELLS | helicase, lymphoid-specific | -0.0184356 |
| IL6ST | interleukin 6 signal transducer | -0.018158 |
| FAM3C | family with sequence similarity 3, member C | -0.0181428 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0180982 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | -0.0180589 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0180326 |
| RDX | radixin | -0.0180064 |
| NOP58 | NOP58 ribonucleoprotein | -0.0178474 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0177599 |
| GOLM2 | golgi membrane protein 2 | -0.0177104 |
| ZFR | zinc finger RNA binding protein | -0.0175885 |
| NSMCE2 | non-SMC element 2, MMS21 homolog (S. cerevisiae) | -0.0174127 |
| PRELID2 | PRELI domain containing 2 | -0.0173997 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0173689 |
