| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | L-Eflornithine (monohydrochloride) perturbation in RKO cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the L-Eflornithine (monohydrochloride)_RKO drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0989195 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0898456 |
| ACTG1 | actin gamma 1 | 0.0825823 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0781633 |
| RPL3 | ribosomal protein L3 | 0.0771367 |
| MCL1 | myeloid cell leukemia 1 | 0.0652601 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0647615 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0642509 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0641282 |
| JMJD1C | jumonji domain containing 1C | 0.0623635 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0596044 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0578105 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0577899 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0576987 |
| UBC | ubiquitin C | 0.0563137 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0546466 |
| CAPRIN2 | caprin family member 2 | 0.0494739 |
| LDHA | lactate dehydrogenase A | 0.0486838 |
| POTEF | POTE ankyrin domain family, member F | 0.0483676 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0468211 |
| CALU | calumenin | 0.046094 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.0453875 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.0451335 |
| DLC1 | DLC1 Rho GTPase activating protein | 0.0441779 |
| FNIP1 | folliculin interacting protein 1 | 0.0432895 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.042175 |
| HDAC9 | histone deacetylase 9 | 0.0418464 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0390358 |
| DGKI | diacylglycerol kinase, iota | 0.0388848 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0382795 |
| SET | SET nuclear proto-oncogene | 0.0381303 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0377933 |
| CORO1C | coronin, actin binding protein, 1C | 0.0371736 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0369531 |
| RASA2 | RAS p21 protein activator 2 | 0.0369459 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0363958 |
| TUT7 | terminal uridylyl transferase 7 | 0.0363476 |
| CREB5 | cAMP responsive element binding protein 5 | 0.0360057 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0341166 |
| LAMB3 | laminin, beta 3 | 0.0336539 |
| ENO1 | enolase 1, (alpha) | 0.0335624 |
| OGA | O-GlcNAcase | 0.0328184 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.032199 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0320078 |
| FAM91A1 | family with sequence similarity 91, member A1 | 0.0316809 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.03151 |
| PGK1 | phosphoglycerate kinase 1 | 0.0314886 |
| FRMD4A | FERM domain containing 4A | 0.0314465 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.0313557 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0309883 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0296843 |
| GLRX | glutaredoxin (thioltransferase) | 0.0291211 |
| TXNRD1 | thioredoxin reductase 1 | 0.0290017 |
| PTK2 | protein tyrosine kinase 2 | 0.0289026 |
| STK4 | serine/threonine kinase 4 | 0.0288028 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.028199 |
| GPATCH2L | G patch domain containing 2-like | 0.0281808 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0280196 |
| RTN4 | reticulon 4 | 0.0276799 |
| VMP1 | vacuole membrane protein 1 | 0.0275107 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0272278 |
| TMF1 | TATA element modulatory factor 1 | 0.0268963 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0268545 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0267567 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0265983 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0264764 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.026404 |
| EFL1 | elongation factor like GTPase 1 | 0.026393 |
| GDI2 | GDP dissociation inhibitor 2 | 0.0263603 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0258653 |
| RCC1 | regulator of chromosome condensation 1 | 0.0257907 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0257664 |
| GLG1 | golgi glycoprotein 1 | 0.0256988 |
| ANO6 | anoctamin 6 | 0.0253847 |
| SETX | senataxin | 0.0253131 |
| BTBD10 | BTB (POZ) domain containing 10 | 0.0252881 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | 0.0252806 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | 0.0251757 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0250364 |
| NBAS | neuroblastoma amplified sequence | 0.0248917 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0248366 |
| CTTN | cortactin | 0.0239123 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0239026 |
| SGMS2 | sphingomyelin synthase 2 | 0.0238527 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0235253 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0234144 |
| THOC2 | THO complex 2 | 0.0232295 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0231464 |
| CANX | calnexin | 0.0231344 |
| MON2 | MON2 homolog (S. cerevisiae) | 0.023105 |
| CALD1 | caldesmon 1 | 0.0229849 |
| FEZ2 | fasciculation and elongation protein zeta 2 (zygin II) | 0.0226856 |
| CRYBG3 | beta-gamma crystallin domain containing 3 | 0.022118 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0219985 |
| WDR26 | WD repeat domain 26 | 0.0219423 |
| MAPK8 | mitogen-activated protein kinase 8 | 0.0215573 |
| RPL4 | ribosomal protein L4 | 0.0215476 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0214854 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0214796 |
| ZNF146 | zinc finger protein 146 | 0.021386 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | -0.168052 |
| RPS6 | ribosomal protein S6 | -0.0815567 |
| PTMA | prothymosin, alpha | -0.0675899 |
| RPL35A | ribosomal protein L35a | -0.0608946 |
| RPS8 | ribosomal protein S8 | -0.0587168 |
| RPLP1 | ribosomal protein, large, P1 | -0.0558358 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0553326 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0490782 |
| RPS21 | ribosomal protein S21 | -0.0487984 |
| TMSB10 | thymosin beta 10 | -0.0465492 |
| RPL8 | ribosomal protein L8 | -0.042179 |
| RPLP2 | ribosomal protein, large, P2 | -0.0410523 |
| RPLP0 | ribosomal protein, large, P0 | -0.040807 |
| GNAS | GNAS complex locus | -0.0397507 |
| RPS19 | ribosomal protein S19 | -0.0390302 |
| HMGA1 | high mobility group AT-hook 1 | -0.0389875 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0375807 |
| RPL11 | ribosomal protein L11 | -0.0371155 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0366862 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.036348 |
| RPL30 | ribosomal protein L30 | -0.0357905 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0353703 |
| RPS24 | ribosomal protein S24 | -0.0346536 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.0339832 |
| RPL23 | ribosomal protein L23 | -0.032308 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0318568 |
| PA2G4 | proliferation-associated 2G4, 38kDa | -0.0317334 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0314727 |
| RPL38 | ribosomal protein L38 | -0.0313496 |
| HMGB1 | high mobility group box 1 | -0.0313137 |
| RPL36 | ribosomal protein L36 | -0.0312764 |
| RPL32 | ribosomal protein L32 | -0.0304865 |
| DIAPH3 | diaphanous-related formin 3 | -0.0297467 |
| RPS15 | ribosomal protein S15 | -0.0278885 |
| RPL37A | ribosomal protein L37a | -0.0276142 |
| RPL12 | ribosomal protein L12 | -0.0272228 |
| RPL19 | ribosomal protein L19 | -0.0270058 |
| CENPF | centromere protein F, 350/400kDa | -0.0268259 |
| RPL5 | ribosomal protein L5 | -0.0267901 |
| RRBP1 | ribosome binding protein 1 | -0.0267846 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0264482 |
| RPS29 | ribosomal protein S29 | -0.0258753 |
| RAB3IP | RAB3A interacting protein | -0.0254422 |
| RPS20 | ribosomal protein S20 | -0.0253631 |
| RPL35 | ribosomal protein L35 | -0.0251544 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0251544 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0251235 |
| HMGB2 | high mobility group box 2 | -0.0245874 |
| RPS13 | ribosomal protein S13 | -0.0243855 |
| USP3 | ubiquitin specific peptidase 3 | -0.0237746 |
| FTL | ferritin, light polypeptide | -0.0236398 |
| SRPK2 | SRSF protein kinase 2 | -0.0234344 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0233336 |
| KRR1 | KRR1, small subunit (SSU) processome component, homolog (yeast) | -0.0232571 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0231432 |
| EEF1B2 | eukaryotic translation elongation factor 1 beta 2 | -0.0231422 |
| RPS25 | ribosomal protein S25 | -0.022863 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0226182 |
| TFRC | transferrin receptor | -0.0224745 |
| ARF1 | ADP-ribosylation factor 1 | -0.022343 |
| GPHN | gephyrin | -0.0221463 |
| RPL34 | ribosomal protein L34 | -0.0220612 |
| MKI67 | marker of proliferation Ki-67 | -0.0220134 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0216632 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | -0.0213542 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | -0.021284 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0212311 |
| MT1X | metallothionein 1X | -0.0211257 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0210914 |
| MX2 | MX dynamin-like GTPase 2 | -0.0209065 |
| LDHB | lactate dehydrogenase B | -0.0208723 |
| TUBA1B | tubulin, alpha 1b | -0.0203392 |
| AHNAK | AHNAK nucleoprotein | -0.0203385 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | -0.0201985 |
| TPX2 | TPX2, microtubule-associated | -0.0201912 |
| MTAP | methylthioadenosine phosphorylase | -0.0201538 |
| WAC | WW domain containing adaptor with coiled-coil | -0.020147 |
| CUX1 | cut-like homeobox 1 | -0.0201396 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0200574 |
| RPS23 | ribosomal protein S23 | -0.020053 |
| DEK | DEK proto-oncogene | -0.0200359 |
| PDS5B | PDS5 cohesin associated factor B | -0.0197257 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0196335 |
| PARD3 | par-3 family cell polarity regulator | -0.0195619 |
| RPL7 | ribosomal protein L7 | -0.0194235 |
| S100A2 | S100 calcium binding protein A2 | -0.0192356 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0191658 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0191566 |
| FUS | FUS RNA binding protein | -0.0190985 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | -0.0190053 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | -0.0188697 |
| MEMO1 | mediator of cell motility 1 | -0.0188595 |
| NDRG1 | N-myc downstream regulated 1 | -0.018755 |
| RPS12 | ribosomal protein S12 | -0.0187184 |
| NUP58 | nucleoporin 58 | -0.0185852 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0185569 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0185022 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0184771 |
| RPS17 | ribosomal protein S17 | -0.0184132 |
| FAM162A | family with sequence similarity 162, member A | -0.0184099 |
