| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | L-Eflornithine (monohydrochloride) perturbation in SK-MEL-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the L-Eflornithine (monohydrochloride)_SK-MEL-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | 0.168646 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.153025 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.132564 |
| FNDC3B | fibronectin type III domain containing 3B | 0.109088 |
| FMN1 | formin 1 | 0.0943468 |
| PRELID2 | PRELI domain containing 2 | 0.0705064 |
| NAV2 | neuron navigator 2 | 0.0582391 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0569357 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0529583 |
| FMNL2 | formin-like 2 | 0.0507785 |
| CD44 | CD44 molecule (Indian blood group) | 0.0486823 |
| MSN | moesin | 0.0458743 |
| SPAG9 | sperm associated antigen 9 | 0.0440877 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | 0.0431361 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0419716 |
| FHIT | fragile histidine triad | 0.0412984 |
| YEATS2 | YEATS domain containing 2 | 0.0408286 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | 0.0405666 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0399209 |
| MT1X | metallothionein 1X | 0.0398538 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0397691 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0390633 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0389111 |
| FNIP1 | folliculin interacting protein 1 | 0.0379166 |
| RAPGEF6 | Rap guanine nucleotide exchange factor (GEF) 6 | 0.0378802 |
| MT2A | metallothionein 2A | 0.0372835 |
| GOLGB1 | golgin B1 | 0.0366382 |
| ICAM1 | intercellular adhesion molecule 1 | 0.0362836 |
| DST | dystonin | 0.0360108 |
| OGA | O-GlcNAcase | 0.0346805 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0345223 |
| CALD1 | caldesmon 1 | 0.0345057 |
| MACROD2 | MACRO domain containing 2 | 0.0340327 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0338607 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0337744 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0337154 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0330188 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0329899 |
| ATXN1 | ataxin 1 | 0.032654 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0325184 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0318023 |
| CLIP4 | CAP-GLY domain containing linker protein family, member 4 | 0.0312897 |
| HDAC9 | histone deacetylase 9 | 0.0306678 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | 0.030598 |
| LDHA | lactate dehydrogenase A | 0.0303043 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0299732 |
| CANX | calnexin | 0.0287681 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0285775 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0283927 |
| RAD51B | RAD51 paralog B | 0.0280266 |
| FER | fer (fps/fes related) tyrosine kinase | 0.0280222 |
| NOTCH2 | notch 2 | 0.0278943 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0278909 |
| AFDN | afadin, adherens junction formation factor | 0.0278578 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0266678 |
| INPP5F | inositol polyphosphate-5-phosphatase F | 0.026524 |
| FLNA | filamin A, alpha | 0.0264518 |
| OPHN1 | oligophrenin 1 | 0.0261106 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0260102 |
| ACTN1 | actinin, alpha 1 | 0.0258726 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0257163 |
| XRCC6 | X-ray repair complementing defective repair in Chinese hamster cells 6 | 0.0257114 |
| VCL | vinculin | 0.025613 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | 0.02551 |
| CRYBG3 | beta-gamma crystallin domain containing 3 | 0.0253026 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0249 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0245909 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0244382 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.024286 |
| DIAPH1 | diaphanous-related formin 1 | 0.0242175 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | 0.0241248 |
| XRN1 | 5'-3' exoribonuclease 1 | 0.0239165 |
| TPM3 | tropomyosin 3 | 0.0238763 |
| CLIC4 | chloride intracellular channel 4 | 0.0237705 |
| KAZN | kazrin, periplakin interacting protein | 0.0234459 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0233945 |
| UBC | ubiquitin C | 0.0233229 |
| USP34 | ubiquitin specific peptidase 34 | 0.0232689 |
| NGLY1 | N-glycanase 1 | 0.023188 |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 | 0.023108 |
| ZNF697 | zinc finger protein 697 | 0.0230428 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0228722 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0228408 |
| TP63 | tumor protein p63 | 0.0227208 |
| FAM219A | family with sequence similarity 219, member A | 0.0226681 |
| IL1RAP | interleukin 1 receptor accessory protein | 0.0225544 |
| CALR | calreticulin | 0.0223803 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0223409 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0220782 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0219333 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.0218053 |
| RLIM | ring finger protein, LIM domain interacting | 0.0217516 |
| GNAI3 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 | 0.0217072 |
| MMP12 | matrix metallopeptidase 12 | 0.0215128 |
| BBX | bobby sox homolog (Drosophila) | 0.0213701 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0213371 |
| ASPH | aspartate beta-hydroxylase | 0.0213161 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0211869 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0211726 |
| CCDC14 | coiled-coil domain containing 14 | 0.0210929 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LSAMP | limbic system-associated membrane protein | -0.164533 |
| VIM | vimentin | -0.135783 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.110751 |
| PTMA | prothymosin, alpha | -0.110726 |
| RPL35A | ribosomal protein L35a | -0.107875 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0965444 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0826354 |
| RPS6 | ribosomal protein S6 | -0.0807071 |
| RPS3 | ribosomal protein S3 | -0.078222 |
| TMSB10 | thymosin beta 10 | -0.0692398 |
| FTL | ferritin, light polypeptide | -0.0677398 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0631972 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | -0.0616613 |
| RPLP1 | ribosomal protein, large, P1 | -0.0605396 |
| NLGN1 | neuroligin 1 | -0.0535516 |
| RPL11 | ribosomal protein L11 | -0.0533462 |
| RPS8 | ribosomal protein S8 | -0.0527219 |
| RPS24 | ribosomal protein S24 | -0.0512168 |
| RPL37A | ribosomal protein L37a | -0.0511152 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0508311 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.049855 |
| RPL31 | ribosomal protein L31 | -0.0493362 |
| RPLP2 | ribosomal protein, large, P2 | -0.0489278 |
| RPS13 | ribosomal protein S13 | -0.048602 |
| RPL34 | ribosomal protein L34 | -0.0469551 |
| RPL38 | ribosomal protein L38 | -0.0465116 |
| S100A9 | S100 calcium binding protein A9 | -0.044803 |
| RPL23 | ribosomal protein L23 | -0.0447897 |
| RPS21 | ribosomal protein S21 | -0.0441817 |
| HLA-B | major histocompatibility complex, class I, B | -0.0434198 |
| IER3 | immediate early response 3 | -0.0430018 |
| RPS12 | ribosomal protein S12 | -0.0417018 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0402893 |
| RPS16 | ribosomal protein S16 | -0.0387716 |
| RPS19 | ribosomal protein S19 | -0.0387029 |
| RPS23 | ribosomal protein S23 | -0.0355234 |
| RPS14 | ribosomal protein S14 | -0.0350561 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0348822 |
| LMNA | lamin A/C | -0.0346203 |
| RPL32 | ribosomal protein L32 | -0.033639 |
| RPS29 | ribosomal protein S29 | -0.0335116 |
| PRAME | preferentially expressed antigen in melanoma | -0.0327234 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.032707 |
| RPL36A | ribosomal protein L36a | -0.0324318 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0322222 |
| RPS27A | ribosomal protein S27a | -0.0320001 |
| PMEL | premelanosome protein | -0.0319914 |
| B2M | beta-2-microglobulin | -0.0318735 |
| RPS17 | ribosomal protein S17 | -0.0316642 |
| CTSD | cathepsin D | -0.0315297 |
| RPL19 | ribosomal protein L19 | -0.0314625 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0313237 |
| RPL36 | ribosomal protein L36 | -0.0311379 |
| RPS15 | ribosomal protein S15 | -0.0296872 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0291885 |
| RPL27 | ribosomal protein L27 | -0.0287128 |
| RPL8 | ribosomal protein L8 | -0.0283905 |
| RPL28 | ribosomal protein L28 | -0.028153 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0278239 |
| RPS25 | ribosomal protein S25 | -0.0275504 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0275474 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | -0.0273749 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0272527 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0271774 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0263809 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0260019 |
| SNU13 | small nuclear ribonucleoprotein 13 | -0.0257576 |
| LITAF | lipopolysaccharide-induced TNF factor | -0.0253225 |
| RPL5 | ribosomal protein L5 | -0.0252652 |
| RPL26 | ribosomal protein L26 | -0.0252208 |
| IFI44L | interferon-induced protein 44-like | -0.0251046 |
| GNAS | GNAS complex locus | -0.0250342 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0250134 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0247298 |
| COX4I1 | cytochrome c oxidase subunit IV isoform 1 | -0.0245588 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0245272 |
| RPS11 | ribosomal protein S11 | -0.0245144 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0244918 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0244374 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0242108 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | -0.0240571 |
| ARPC1B | actin related protein 2/3 complex, subunit 1B, 41kDa | -0.0237981 |
| RPL9 | ribosomal protein L9 | -0.0235492 |
| RPL37 | ribosomal protein L37 | -0.0226942 |
| NOP58 | NOP58 ribonucleoprotein | -0.022556 |
| RPS5 | ribosomal protein S5 | -0.0224643 |
| ATF4 | activating transcription factor 4 | -0.0223479 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0222941 |
| FAM162A | family with sequence similarity 162, member A | -0.0221429 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.021836 |
| RPL7A | ribosomal protein L7a | -0.0217707 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0215547 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0214696 |
| RPL15 | ribosomal protein L15 | -0.0214412 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0211042 |
| HMGA1 | high mobility group AT-hook 1 | -0.0209974 |
| SP100 | SP100 nuclear antigen | -0.0209633 |
| UQCRQ | ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa | -0.0207251 |
| PA2G4 | proliferation-associated 2G4, 38kDa | -0.0207136 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | -0.0204336 |
