| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | L-Eflornithine (monohydrochloride) perturbation in SNU-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the L-Eflornithine (monohydrochloride)_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.140442 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.133732 |
| TJP1 | tight junction protein 1 | 0.115979 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.102235 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0938504 |
| VCL | vinculin | 0.0908266 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0874086 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0821567 |
| NBEA | neurobeachin | 0.0776503 |
| TXNRD1 | thioredoxin reductase 1 | 0.0765125 |
| SOX6 | SRY (sex determining region Y)-box 6 | 0.0745346 |
| PDGFC | platelet derived growth factor C | 0.0730142 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0715528 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0701951 |
| ZNF608 | zinc finger protein 608 | 0.0692608 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0642338 |
| UBC | ubiquitin C | 0.0608678 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0581461 |
| TGFBR3 | transforming growth factor, beta receptor III | 0.0579563 |
| EZR | ezrin | 0.0559341 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.051578 |
| FLNB | filamin B, beta | 0.0514549 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0510283 |
| LDHA | lactate dehydrogenase A | 0.0505715 |
| ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 | 0.0462682 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0459004 |
| EGFR | epidermal growth factor receptor | 0.0457353 |
| GLI2 | GLI family zinc finger 2 | 0.0455418 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0447738 |
| QKI | QKI, KH domain containing, RNA binding | 0.0441 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0438634 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0437768 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0433856 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0428921 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0419298 |
| DUSP4 | dual specificity phosphatase 4 | 0.0416993 |
| SEC24D | SEC24 family member D | 0.0414073 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0402335 |
| RAB27B | RAB27B, member RAS oncogene family | 0.0401534 |
| RRBP1 | ribosome binding protein 1 | 0.0398604 |
| EFNA5 | ephrin-A5 | 0.0398088 |
| PRELID2 | PRELI domain containing 2 | 0.039303 |
| GOLGA4 | golgin A4 | 0.039293 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0389781 |
| SQSTM1 | sequestosome 1 | 0.0385348 |
| AHCYL2 | adenosylhomocysteinase-like 2 | 0.0381097 |
| ZNF292 | zinc finger protein 292 | 0.0370149 |
| ANK2 | ankyrin 2, neuronal | 0.0366353 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.0356963 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0355242 |
| HDLBP | high density lipoprotein binding protein | 0.0355212 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0343011 |
| ALDH3A2 | aldehyde dehydrogenase 3 family, member A2 | 0.0339508 |
| PHF3 | PHD finger protein 3 | 0.0336335 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0336302 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0334058 |
| RTN4 | reticulon 4 | 0.0328399 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.0321857 |
| DIAPH2 | diaphanous-related formin 2 | 0.0320136 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0313792 |
| PUM2 | pumilio RNA-binding family member 2 | 0.031347 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0313375 |
| ENOX1 | ecto-NOX disulfide-thiol exchanger 1 | 0.0312847 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0310851 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0310113 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.0309031 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0306453 |
| CALU | calumenin | 0.0305389 |
| RBM26 | RNA binding motif protein 26 | 0.0304627 |
| INTS6 | integrator complex subunit 6 | 0.0301941 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0299782 |
| TMEM263 | transmembrane protein 263 | 0.0299431 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0298035 |
| PGM3 | phosphoglucomutase 3 | 0.0295298 |
| COPA | coatomer protein complex, subunit alpha | 0.0295205 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | 0.0289472 |
| RPL4 | ribosomal protein L4 | 0.0287448 |
| TRIM44 | tripartite motif containing 44 | 0.0286678 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0284184 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0280873 |
| NCOA3 | nuclear receptor coactivator 3 | 0.0280515 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0277746 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0277066 |
| USP47 | ubiquitin specific peptidase 47 | 0.0275192 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | 0.0273538 |
| CLIP1 | CAP-GLY domain containing linker protein 1 | 0.0272406 |
| HEG1 | heart development protein with EGF-like domains 1 | 0.0272136 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.027139 |
| NT5C2 | 5'-nucleotidase, cytosolic II | 0.0266203 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0265852 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0264466 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0264287 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0262897 |
| VMP1 | vacuole membrane protein 1 | 0.0262529 |
| ANXA1 | annexin A1 | 0.0262518 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0259223 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | 0.025906 |
| PMM2 | phosphomannomutase 2 | 0.0257649 |
| ACTG1 | actin gamma 1 | 0.0255548 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0254958 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.166824 |
| RPL35A | ribosomal protein L35a | -0.0813626 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0746131 |
| RPS6 | ribosomal protein S6 | -0.072271 |
| BMP10 | bone morphogenetic protein 10 | -0.0719752 |
| MKI67 | marker of proliferation Ki-67 | -0.0683112 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.058729 |
| RPLP1 | ribosomal protein, large, P1 | -0.0484788 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0483985 |
| RPL23 | ribosomal protein L23 | -0.04362 |
| CENPF | centromere protein F, 350/400kDa | -0.0429618 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0419656 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0414661 |
| AHNAK | AHNAK nucleoprotein | -0.0405193 |
| RPLP2 | ribosomal protein, large, P2 | -0.0392957 |
| RPL34 | ribosomal protein L34 | -0.0380563 |
| PFN1 | profilin 1 | -0.0369307 |
| EVI5 | ecotropic viral integration site 5 | -0.0354397 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0352238 |
| S100A9 | S100 calcium binding protein A9 | -0.0346666 |
| LOXL3 | lysyl oxidase-like 3 | -0.0346161 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0340431 |
| UNC13A | unc-13 homolog A (C. elegans) | -0.0340059 |
| CUX1 | cut-like homeobox 1 | -0.0339655 |
| S100A4 | S100 calcium binding protein A4 | -0.0339271 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.033137 |
| HLA-B | major histocompatibility complex, class I, B | -0.0330642 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0330209 |
| EBNA1BP2 | EBNA1 binding protein 2 | -0.0330015 |
| RPL31 | ribosomal protein L31 | -0.0327839 |
| RPS21 | ribosomal protein S21 | -0.0326645 |
| EMP3 | epithelial membrane protein 3 | -0.0320104 |
| DIAPH3 | diaphanous-related formin 3 | -0.0316669 |
| HJURP | Holliday junction recognition protein | -0.0316338 |
| TNFRSF11B | tumor necrosis factor receptor superfamily, member 11b | -0.0314872 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0308473 |
| RPL37A | ribosomal protein L37a | -0.030615 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0289858 |
| PARD3 | par-3 family cell polarity regulator | -0.02893 |
| HMGA1 | high mobility group AT-hook 1 | -0.0286417 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0280138 |
| SMIM44 | small integral membrane protein 44 | -0.027974 |
| ITGA10 | integrin, alpha 10 | -0.0279089 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -0.0278025 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.026883 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0267033 |
| SMNDC1 | survival motor neuron domain containing 1 | -0.0266238 |
| TOB1 | transducer of ERBB2, 1 | -0.0263946 |
| GNAS | GNAS complex locus | -0.0262931 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0259615 |
| RPS19 | ribosomal protein S19 | -0.0258614 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0258362 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0254708 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | -0.024457 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.024121 |
| CRPPA | CDP-L-ribitol pyrophosphorylase A | -0.0239413 |
| MYL12B | myosin, light chain 12B, regulatory | -0.023834 |
| RPL9 | ribosomal protein L9 | -0.0237946 |
| RBM25 | RNA binding motif protein 25 | -0.0236729 |
| RPL36 | ribosomal protein L36 | -0.023386 |
| ATAD2 | ATPase family, AAA domain containing 2 | -0.0225053 |
| FOXP1 | forkhead box P1 | -0.0224018 |
| CDR2 | cerebellar degeneration-related protein 2, 62kDa | -0.0223193 |
| RAN | RAN, member RAS oncogene family | -0.0222161 |
| POTEF | POTE ankyrin domain family, member F | -0.0215368 |
| RFC3 | replication factor C (activator 1) 3, 38kDa | -0.0213998 |
| PCBP2 | poly(rC) binding protein 2 | -0.0209193 |
| RPS23 | ribosomal protein S23 | -0.0207774 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | -0.0207569 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | -0.0205529 |
| CHD4 | chromodomain helicase DNA binding protein 4 | -0.0205229 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0204805 |
| JMJD1C | jumonji domain containing 1C | -0.0204447 |
| RPL15 | ribosomal protein L15 | -0.020334 |
| RHOA | ras homolog family member A | -0.0201834 |
| PRSS23 | protease, serine, 23 | -0.0201648 |
| RPL36A | ribosomal protein L36a | -0.0200847 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0200225 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0199478 |
| RBL1 | retinoblastoma-like 1 | -0.0198785 |
| SEPTIN9 | septin 9 | -0.0194423 |
| ASTN2 | astrotactin 2 | -0.0194072 |
| PTMS | parathymosin | -0.0193451 |
| TMSB10 | thymosin beta 10 | -0.0191886 |
| ZNF438 | zinc finger protein 438 | -0.0191388 |
| DEK | DEK proto-oncogene | -0.0190631 |
| RPS13 | ribosomal protein S13 | -0.0189673 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0188049 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | -0.0186487 |
| SIK3 | SIK family kinase 3 | -0.0186447 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0186046 |
| PA2G4 | proliferation-associated 2G4, 38kDa | -0.0185792 |
| GSE1 | Gse1 coiled-coil protein | -0.0182898 |
| ACACA | acetyl-CoA carboxylase alpha | -0.0182362 |
| TUBA1B | tubulin, alpha 1b | -0.0181533 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0181206 |
| PRMT2 | protein arginine methyltransferase 2 | -0.0180508 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | -0.0179439 |
| PKP4 | plakophilin 4 | -0.0179363 |
| RPS14 | ribosomal protein S14 | -0.0178871 |
