| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | L-Eflornithine (monohydrochloride) perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the L-Eflornithine (monohydrochloride)_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SOD2 | superoxide dismutase 2, mitochondrial | 0.133944 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.128498 |
| FN1 | fibronectin 1 | 0.0968145 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0894015 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0737256 |
| OGA | O-GlcNAcase | 0.0726189 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0645462 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0613194 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.054977 |
| MYOF | myoferlin | 0.0549439 |
| DST | dystonin | 0.0548849 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0544064 |
| PDE10A | phosphodiesterase 10A | 0.0543354 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0532656 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0521828 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0515134 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0503521 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0492359 |
| UBC | ubiquitin C | 0.0481716 |
| AHNAK | AHNAK nucleoprotein | 0.047335 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0461851 |
| ZNF292 | zinc finger protein 292 | 0.0454646 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.044458 |
| NAV2 | neuron navigator 2 | 0.0434923 |
| SPAG9 | sperm associated antigen 9 | 0.0430347 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0426903 |
| CUL4B | cullin 4B | 0.040988 |
| ARRDC3 | arrestin domain containing 3 | 0.0393231 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0386989 |
| SMAD3 | SMAD family member 3 | 0.0383206 |
| CANX | calnexin | 0.0382047 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0375146 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.036718 |
| SLC38A2 | solute carrier family 38, member 2 | 0.035931 |
| RBM39 | RNA binding motif protein 39 | 0.0358807 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0355134 |
| LDHA | lactate dehydrogenase A | 0.0346613 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0345776 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0340352 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0335935 |
| LAMP2 | lysosomal-associated membrane protein 2 | 0.0328677 |
| PHF3 | PHD finger protein 3 | 0.0315215 |
| VCL | vinculin | 0.0314684 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0308581 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0307916 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0307284 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0291486 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0290412 |
| AHR | aryl hydrocarbon receptor | 0.0287141 |
| ANXA2 | annexin A2 | 0.0283853 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0278318 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0276281 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0272479 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0272421 |
| PRELID2 | PRELI domain containing 2 | 0.0268332 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0266184 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0264857 |
| ANLN | anillin, actin binding protein | 0.0263957 |
| SBF2 | SET binding factor 2 | 0.0261133 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.02601 |
| SDC4 | syndecan 4 | 0.0257691 |
| APP | amyloid beta (A4) precursor protein | 0.0257671 |
| FOXO3 | forkhead box O3 | 0.0256457 |
| RPL14 | ribosomal protein L14 | 0.0255318 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0251576 |
| RTN4 | reticulon 4 | 0.0250852 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0248307 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0246452 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | 0.0243729 |
| PGK1 | phosphoglycerate kinase 1 | 0.0243114 |
| NCOA7 | nuclear receptor coactivator 7 | 0.024134 |
| HELZ | helicase with zinc finger | 0.023855 |
| GOLGB1 | golgin B1 | 0.0234438 |
| OPTN | optineurin | 0.0225922 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.022441 |
| FLNB | filamin B, beta | 0.0220002 |
| MKI67 | marker of proliferation Ki-67 | 0.0219364 |
| CEP250 | centrosomal protein 250kDa | 0.0217306 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0213516 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0213412 |
| ENO1 | enolase 1, (alpha) | 0.02124 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked | 0.0212016 |
| PLPP6 | phospholipid phosphatase 6 | 0.0210974 |
| STAG2 | stromal antigen 2 | 0.0209907 |
| KLF6 | Kruppel-like factor 6 | 0.0207222 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0206651 |
| RPL4 | ribosomal protein L4 | 0.0205794 |
| ARFGEF3 | ARFGEF family member 3 | 0.0204787 |
| FNIP1 | folliculin interacting protein 1 | 0.0203842 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0202667 |
| CD2AP | CD2-associated protein | 0.0199924 |
| NEK7 | NIMA-related kinase 7 | 0.0199737 |
| VEGFA | vascular endothelial growth factor A | 0.0199345 |
| RIGI | RNA sensor RIG-I | 0.0198597 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0195403 |
| ZNF608 | zinc finger protein 608 | 0.0195177 |
| CENPF | centromere protein F, 350/400kDa | 0.0193975 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0193411 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.019235 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.019157 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.209467 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0946008 |
| TMSB10 | thymosin beta 10 | -0.0715078 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0693167 |
| HLA-B | major histocompatibility complex, class I, B | -0.0651407 |
| GLIS3 | GLIS family zinc finger 3 | -0.0631549 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0522745 |
| NDRG1 | N-myc downstream regulated 1 | -0.0514675 |
| CDH13 | cadherin 13 | -0.0514559 |
| FRMD4A | FERM domain containing 4A | -0.0498548 |
| EGR1 | early growth response 1 | -0.0484635 |
| HMGA2 | high mobility group AT-hook 2 | -0.0483477 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0471463 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0435855 |
| ADM | adrenomedullin | -0.0425104 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0424589 |
| CTSD | cathepsin D | -0.0412984 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.036468 |
| PLIN2 | perilipin 2 | -0.0361298 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0359293 |
| HMGA1 | high mobility group AT-hook 1 | -0.0341189 |
| RPL35A | ribosomal protein L35a | -0.0326169 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0323565 |
| HLA-A | major histocompatibility complex, class I, A | -0.0316125 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0315004 |
| CLMP | CXADR-like membrane protein | -0.0308018 |
| CD44 | CD44 molecule (Indian blood group) | -0.0306805 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0284682 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0273154 |
| FTL | ferritin, light polypeptide | -0.0272514 |
| RPS21 | ribosomal protein S21 | -0.0272217 |
| ARFGAP3 | ADP-ribosylation factor GTPase activating protein 3 | -0.0269232 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0243066 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0238204 |
| NAV1 | neuron navigator 1 | -0.0235102 |
| SAMD3 | sterile alpha motif domain containing 3 | -0.0233329 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.022763 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0226812 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0219578 |
| AFF3 | AF4/FMR2 family, member 3 | -0.0219277 |
| C3 | complement component 3 | -0.0218423 |
| RPL9 | ribosomal protein L9 | -0.0217847 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0217052 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0214174 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0207902 |
| INHBA | inhibin, beta A | -0.020046 |
| GRIN2A | glutamate receptor, ionotropic, N-methyl D-aspartate 2A | -0.0198212 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0197415 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0195418 |
| S100A9 | S100 calcium binding protein A9 | -0.0195329 |
| KRT19 | keratin 19, type I | -0.0193173 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.0187839 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0187197 |
| IER3 | immediate early response 3 | -0.0183429 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0182963 |
| TMEM132D | transmembrane protein 132D | -0.0182315 |
| BNC2 | basonuclin 2 | -0.0182021 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0180501 |
| DIAPH2 | diaphanous-related formin 2 | -0.0177828 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0177431 |
| STC2 | stanniocalcin 2 | -0.017472 |
| PFN1 | profilin 1 | -0.0174707 |
| TPM4 | tropomyosin 4 | -0.017338 |
| MT2A | metallothionein 2A | -0.0173251 |
| FRMPD4 | FERM and PDZ domain containing 4 | -0.0164406 |
| ADAM12 | ADAM metallopeptidase domain 12 | -0.0163844 |
| SFRP1 | secreted frizzled-related protein 1 | -0.0163633 |
| IL6 | interleukin 6 | -0.0155957 |
| RPL37A | ribosomal protein L37a | -0.0155915 |
| LSAMP | limbic system-associated membrane protein | -0.0154671 |
| ATF4 | activating transcription factor 4 | -0.0153583 |
| RPS23 | ribosomal protein S23 | -0.0153356 |
| ASTN2 | astrotactin 2 | -0.0149772 |
| EGFR | epidermal growth factor receptor | -0.0147846 |
| EFNA5 | ephrin-A5 | -0.0147031 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 | -0.0145596 |
| SLC43A3 | solute carrier family 43, member 3 | -0.014535 |
| RAI14 | retinoic acid induced 14 | -0.0142262 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0142227 |
| RPS19 | ribosomal protein S19 | -0.014147 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0141264 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0140775 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0139681 |
| ERGIC1 | endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1 | -0.0139028 |
| GSTO1 | glutathione S-transferase omega 1 | -0.0137817 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0137685 |
| RPS14 | ribosomal protein S14 | -0.0137102 |
| FOXP1 | forkhead box P1 | -0.0136964 |
| ADAMTS12 | ADAM metallopeptidase with thrombospondin type 1 motif, 12 | -0.0133861 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0132975 |
| RPS10 | ribosomal protein S10 | -0.0132305 |
| RND3 | Rho family GTPase 3 | -0.0131929 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.013088 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0130858 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0129283 |
| CD63 | CD63 molecule | -0.0128102 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0126153 |
| SCGB1D1 | secretoglobin, family 1D, member 1 | -0.012591 |
| NRP1 | neuropilin 1 | -0.0124107 |
| RBM3 | RNA binding motif (RNP1, RRM) protein 3 | -0.0122264 |
