| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | L-Eflornithine (monohydrochloride) perturbation in SW1417 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the L-Eflornithine (monohydrochloride)_SW1417 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.110024 |
| DSPP | dentin sialophosphoprotein | 0.0977906 |
| H1-0 | H1.0 linker histone | 0.0856191 |
| EZR | ezrin | 0.084204 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0833068 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0799215 |
| GOLGA4 | golgin A4 | 0.0749363 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0748201 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0710234 |
| LDHA | lactate dehydrogenase A | 0.068493 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0662493 |
| TPX2 | TPX2, microtubule-associated | 0.0660386 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0658446 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0625593 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0625473 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0611513 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | 0.0603745 |
| XPO1 | exportin 1 | 0.059149 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0588803 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0555898 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0519992 |
| AHNAK | AHNAK nucleoprotein | 0.0517534 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0517185 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0516707 |
| CENPF | centromere protein F, 350/400kDa | 0.0513109 |
| UBC | ubiquitin C | 0.0505313 |
| NR1D2 | nuclear receptor subfamily 1, group D, member 2 | 0.0503641 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0499212 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0498988 |
| MKI67 | marker of proliferation Ki-67 | 0.0497381 |
| KRT18 | keratin 18, type I | 0.0478052 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0471395 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0463687 |
| HDLBP | high density lipoprotein binding protein | 0.0455641 |
| CALU | calumenin | 0.0444922 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0438395 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0419725 |
| ZNF292 | zinc finger protein 292 | 0.0417571 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0416526 |
| OSBPL3 | oxysterol binding protein-like 3 | 0.0405134 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0402868 |
| BBX | bobby sox homolog (Drosophila) | 0.0396974 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0389664 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0387286 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0372624 |
| TMEM123 | transmembrane protein 123 | 0.0371707 |
| STT3B | STT3B, subunit of the oligosaccharyltransferase complex (catalytic) | 0.037049 |
| SKAP2 | src kinase associated phosphoprotein 2 | 0.0368565 |
| SPAG9 | sperm associated antigen 9 | 0.0368333 |
| TXNIP | thioredoxin interacting protein | 0.0366284 |
| TMF1 | TATA element modulatory factor 1 | 0.0364953 |
| SON | SON DNA binding protein | 0.0359762 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0357584 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.0356022 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.035573 |
| FNBP1L | formin binding protein 1-like | 0.0355221 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0354107 |
| SNX9 | sorting nexin 9 | 0.0353988 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0353334 |
| FAT1 | FAT atypical cadherin 1 | 0.0347565 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | 0.0347058 |
| APP | amyloid beta (A4) precursor protein | 0.0343401 |
| OXR1 | oxidation resistance 1 | 0.0342618 |
| MATR3 | matrin 3 | 0.0341432 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0339737 |
| OGA | O-GlcNAcase | 0.0339052 |
| XRN2 | 5'-3' exoribonuclease 2 | 0.0335209 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0331966 |
| EPCAM | epithelial cell adhesion molecule | 0.0330597 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.0323668 |
| AFDN | afadin, adherens junction formation factor | 0.0322718 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0321839 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.0321706 |
| LARS1 | leucyl-tRNA synthetase 1 | 0.0319088 |
| TLK1 | tousled-like kinase 1 | 0.0317385 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.0317244 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0316954 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0315011 |
| MED13L | mediator complex subunit 13-like | 0.0312898 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0311386 |
| MLEC | malectin | 0.0310344 |
| SMC5 | structural maintenance of chromosomes 5 | 0.0308392 |
| TMEM41B | transmembrane protein 41B | 0.0306709 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0304315 |
| CDCP1 | CUB domain containing protein 1 | 0.0299803 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0296735 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0295598 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0295529 |
| G3BP1 | GTPase activating protein (SH3 domain) binding protein 1 | 0.0292791 |
| GPSM2 | G-protein signaling modulator 2 | 0.0291482 |
| HMGB2 | high mobility group box 2 | 0.0290124 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | 0.028701 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | 0.0285137 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0284182 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0283929 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0283157 |
| FAM3C | family with sequence similarity 3, member C | 0.0281599 |
| TFDP2 | transcription factor Dp-2 (E2F dimerization partner 2) | 0.0280454 |
| MYOF | myoferlin | 0.0279602 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0279536 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.212007 |
| FTL | ferritin, light polypeptide | -0.130403 |
| RPL35A | ribosomal protein L35a | -0.112708 |
| TMSB10 | thymosin beta 10 | -0.10999 |
| RPS6 | ribosomal protein S6 | -0.0985159 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0957667 |
| RPS13 | ribosomal protein S13 | -0.0678926 |
| RPL37A | ribosomal protein L37a | -0.0659648 |
| RPL31 | ribosomal protein L31 | -0.0607315 |
| GNAS | GNAS complex locus | -0.0604703 |
| RPS25 | ribosomal protein S25 | -0.0593033 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | -0.0545513 |
| RPS12 | ribosomal protein S12 | -0.0534636 |
| RPS21 | ribosomal protein S21 | -0.0522143 |
| RPS29 | ribosomal protein S29 | -0.0507682 |
| RPLP2 | ribosomal protein, large, P2 | -0.0505778 |
| INTS6 | integrator complex subunit 6 | -0.0485171 |
| RPS27A | ribosomal protein S27a | -0.0473298 |
| RPL9 | ribosomal protein L9 | -0.0423893 |
| CCND1 | cyclin D1 | -0.0421288 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0412054 |
| RPS8 | ribosomal protein S8 | -0.0409476 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0407418 |
| RPS23 | ribosomal protein S23 | -0.0401484 |
| MYH14 | myosin, heavy chain 14, non-muscle | -0.0370772 |
| RPS17 | ribosomal protein S17 | -0.0367535 |
| HLA-A | major histocompatibility complex, class I, A | -0.0367117 |
| RPL7A | ribosomal protein L7a | -0.0349971 |
| RPL36 | ribosomal protein L36 | -0.0340954 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0331448 |
| RPLP1 | ribosomal protein, large, P1 | -0.0325699 |
| RPL23 | ribosomal protein L23 | -0.0313716 |
| RPS15 | ribosomal protein S15 | -0.0310355 |
| HMGA1 | high mobility group AT-hook 1 | -0.0309104 |
| RPS3 | ribosomal protein S3 | -0.0308676 |
| RPL38 | ribosomal protein L38 | -0.0306308 |
| RPS16 | ribosomal protein S16 | -0.0301597 |
| HM13 | histocompatibility (minor) 13 | -0.0295341 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0294523 |
| RPS24 | ribosomal protein S24 | -0.0292728 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0288028 |
| RPS19 | ribosomal protein S19 | -0.0287325 |
| RPS11 | ribosomal protein S11 | -0.0283745 |
| RPL37 | ribosomal protein L37 | -0.0271755 |
| S100A2 | S100 calcium binding protein A2 | -0.0268604 |
| UBE2R2 | ubiquitin-conjugating enzyme E2R 2 | -0.0265873 |
| RPL34 | ribosomal protein L34 | -0.0264509 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0261731 |
| RPL28 | ribosomal protein L28 | -0.0259127 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0259019 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0258996 |
| S100A11 | S100 calcium binding protein A11 | -0.0256526 |
| RPL11 | ribosomal protein L11 | -0.0255115 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0253983 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0253822 |
| SIK3 | SIK family kinase 3 | -0.0252307 |
| RCOR1 | REST corepressor 1 | -0.0246754 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0245307 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | -0.0243941 |
| ACTG1 | actin gamma 1 | -0.0241671 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | -0.0239102 |
| HLA-B | major histocompatibility complex, class I, B | -0.0238191 |
| IER3 | immediate early response 3 | -0.0237047 |
| CMIP | c-Maf inducing protein | -0.0236881 |
| EHMT1 | euchromatic histone-lysine N-methyltransferase 1 | -0.023624 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0235293 |
| CST3 | cystatin C | -0.0233522 |
| RPS10 | ribosomal protein S10 | -0.0232401 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0231709 |
| KLK10 | kallikrein-related peptidase 10 | -0.0230153 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 | -0.0228433 |
| RPL13A | ribosomal protein L13a | -0.0224329 |
| PPARD | peroxisome proliferator-activated receptor delta | -0.0222582 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0221629 |
| EEF1B2 | eukaryotic translation elongation factor 1 beta 2 | -0.0218576 |
| RPL5 | ribosomal protein L5 | -0.0218559 |
| CD9 | CD9 molecule | -0.0215148 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0213034 |
| VOPP1 | vesicular, overexpressed in cancer, prosurvival protein 1 | -0.0212359 |
| JUP | junction plakoglobin | -0.0210503 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0209351 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0204012 |
| UQCRQ | ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa | -0.0201421 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.019939 |
| HDGF | hepatoma-derived growth factor | -0.0198359 |
| CTSD | cathepsin D | -0.019754 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | -0.019706 |
| MAP3K8 | mitogen-activated protein kinase kinase kinase 8 | -0.0194016 |
| PKM | pyruvate kinase, muscle | -0.0192001 |
| KCNH8 | potassium channel, voltage gated eag related subfamily H, member 8 | -0.0191884 |
| HNF1A | HNF1 homeobox A | -0.0190177 |
| S100P | S100 calcium binding protein P | -0.0189115 |
| TRMT112 | tRNA methyltransferase 11-2 homolog (S. cerevisiae) | -0.0187232 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | -0.01869 |
| MXD1 | MAX dimerization protein 1 | -0.0184226 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.018103 |
| AGO3 | argonaute RISC catalytic component 3 | -0.0180129 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 | -0.0179758 |
| MAP3K13 | mitogen-activated protein kinase kinase kinase 13 | -0.017857 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0176869 |
