| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | L-Eflornithine (monohydrochloride) perturbation in SW480 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the L-Eflornithine (monohydrochloride)_SW480 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.203635 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.159392 |
| ENO1 | enolase 1, (alpha) | 0.151604 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.14907 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.120245 |
| PDGFA | platelet-derived growth factor alpha polypeptide | 0.11565 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.115424 |
| ITGA6 | integrin, alpha 6 | 0.106658 |
| KRT8 | keratin 8, type II | 0.100796 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0951926 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0937725 |
| VCL | vinculin | 0.0915969 |
| LDHA | lactate dehydrogenase A | 0.0895639 |
| KRT18 | keratin 18, type I | 0.086045 |
| PGK1 | phosphoglycerate kinase 1 | 0.0829698 |
| ACTN4 | actinin, alpha 4 | 0.075794 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0756091 |
| CANX | calnexin | 0.070781 |
| AHNAK | AHNAK nucleoprotein | 0.0704818 |
| ANLN | anillin, actin binding protein | 0.0700676 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0653264 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0627746 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0598677 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.0598541 |
| UBC | ubiquitin C | 0.0595428 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0591782 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0587442 |
| DSPP | dentin sialophosphoprotein | 0.0581786 |
| BCL2L1 | BCL2-like 1 | 0.057688 |
| PKM | pyruvate kinase, muscle | 0.0572004 |
| ANXA2 | annexin A2 | 0.0547637 |
| DST | dystonin | 0.0546941 |
| VMP1 | vacuole membrane protein 1 | 0.0545147 |
| EZR | ezrin | 0.0537973 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0526697 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0525301 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0522033 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0521355 |
| ASPH | aspartate beta-hydroxylase | 0.051722 |
| ANO1 | anoctamin 1, calcium activated chloride channel | 0.0509631 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.050471 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0503373 |
| SLC1A5 | solute carrier family 1 (neutral amino acid transporter), member 5 | 0.05025 |
| MED13 | mediator complex subunit 13 | 0.04882 |
| SDC4 | syndecan 4 | 0.0484724 |
| HMGB2 | high mobility group box 2 | 0.0469321 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0467062 |
| MYOF | myoferlin | 0.0465585 |
| NEBL | nebulette | 0.0462825 |
| RPL3 | ribosomal protein L3 | 0.0461447 |
| TPM4 | tropomyosin 4 | 0.0457299 |
| PTMA | prothymosin, alpha | 0.0455403 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0441492 |
| FLNB | filamin B, beta | 0.0432136 |
| ZNF638 | zinc finger protein 638 | 0.0428704 |
| OSBPL3 | oxysterol binding protein-like 3 | 0.0425794 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.0421327 |
| H1-0 | H1.0 linker histone | 0.0421186 |
| NAV2 | neuron navigator 2 | 0.0416308 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0415471 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0415107 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0415098 |
| FYN | FYN proto-oncogene, Src family tyrosine kinase | 0.0408523 |
| ACTN1 | actinin, alpha 1 | 0.0407848 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0407568 |
| CDH13 | cadherin 13 | 0.0407179 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0406653 |
| SPATA13 | spermatogenesis associated 13 | 0.0398027 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0393783 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0392553 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.039085 |
| CD46 | CD46 molecule, complement regulatory protein | 0.0390375 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0390292 |
| NTSR1 | neurotensin receptor 1 (high affinity) | 0.038714 |
| SEPTIN9 | septin 9 | 0.0382992 |
| EGR1 | early growth response 1 | 0.0382789 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0379272 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | 0.0376047 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0373053 |
| TMSB4X | thymosin beta 4, X-linked | 0.0371284 |
| RPL4 | ribosomal protein L4 | 0.0369256 |
| ITGB4 | integrin, beta 4 | 0.0367901 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | 0.0366893 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0365572 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0364347 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0364019 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.036218 |
| TUBB | tubulin, beta class I | 0.0360003 |
| CCND1 | cyclin D1 | 0.0359884 |
| MKI67 | marker of proliferation Ki-67 | 0.0354269 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0353026 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0349058 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0344356 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0342214 |
| KIZ | kizuna centrosomal protein | 0.0341815 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0341416 |
| POTEF | POTE ankyrin domain family, member F | 0.0340976 |
| SNX9 | sorting nexin 9 | 0.0330391 |
| ECT2 | epithelial cell transforming 2 | 0.0329592 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0327772 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0897151 |
| RPS2 | ribosomal protein S2 | -0.0829465 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0723529 |
| SYT1 | synaptotagmin I | -0.0706274 |
| RPS6 | ribosomal protein S6 | -0.0558629 |
| WWOX | WW domain containing oxidoreductase | -0.047874 |
| RPS12 | ribosomal protein S12 | -0.0414846 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | -0.0383207 |
| RPL7 | ribosomal protein L7 | -0.0377202 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.0365803 |
| RPL9 | ribosomal protein L9 | -0.0362487 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0347272 |
| ARL15 | ADP-ribosylation factor-like 15 | -0.03179 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0310863 |
| TNS3 | tensin 3 | -0.0295412 |
| VGLL4 | vestigial-like family member 4 | -0.0292296 |
| GPHN | gephyrin | -0.028375 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0265749 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0263683 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0262137 |
| RPL38 | ribosomal protein L38 | -0.0261084 |
| RPL19 | ribosomal protein L19 | -0.0259921 |
| RPL37A | ribosomal protein L37a | -0.0253174 |
| PIBF1 | progesterone immunomodulatory binding factor 1 | -0.025051 |
| BMP5 | bone morphogenetic protein 5 | -0.0247348 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0229228 |
| RPL5 | ribosomal protein L5 | -0.0217276 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | -0.0211507 |
| NKTR | natural killer cell triggering receptor | -0.0200684 |
| RPL11 | ribosomal protein L11 | -0.0199907 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | -0.0199807 |
| MMS22L | MMS22-like, DNA repair protein | -0.0194239 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0192762 |
| RPS8 | ribosomal protein S8 | -0.0192125 |
| HELZ | helicase with zinc finger | -0.0190097 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0189858 |
| RPS23 | ribosomal protein S23 | -0.0187754 |
| RPLP2 | ribosomal protein, large, P2 | -0.0184386 |
| TNRC6A | trinucleotide repeat containing 6A | -0.0183053 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0179721 |
| RPL27 | ribosomal protein L27 | -0.0177983 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0177445 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0177047 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0176966 |
| RPS21 | ribosomal protein S21 | -0.0176414 |
| UBR3 | ubiquitin protein ligase E3 component n-recognin 3 (putative) | -0.0174546 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | -0.0174186 |
| POLA1 | polymerase (DNA directed), alpha 1, catalytic subunit | -0.017403 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -0.0171779 |
| RPL36 | ribosomal protein L36 | -0.0168922 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -0.0168537 |
| SPIDR | scaffolding protein involved in DNA repair | -0.0167818 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0166504 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.0166476 |
| RPL26 | ribosomal protein L26 | -0.0164933 |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain | -0.0161318 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 | -0.0159601 |
| ELP4 | elongator acetyltransferase complex subunit 4 | -0.0159538 |
| SBF2 | SET binding factor 2 | -0.015944 |
| HLCS | holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase) | -0.0158937 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | -0.0156702 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | -0.0156466 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | -0.0156029 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.0153689 |
| RECQL | RecQ helicase-like | -0.0152338 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.0152295 |
| SMYD3 | SET and MYND domain containing 3 | -0.0151272 |
| RNF43 | ring finger protein 43 | -0.015112 |
| HMGA1 | high mobility group AT-hook 1 | -0.0149964 |
| ICE1 | interactor of little elongation complex ELL subunit 1 | -0.0149847 |
| RBM39 | RNA binding motif protein 39 | -0.0148148 |
| UBQLN1 | ubiquilin 1 | -0.014633 |
| H1-4 | H1.4 linker histone, cluster member | -0.0144673 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | -0.0143697 |
| AGO3 | argonaute RISC catalytic component 3 | -0.014271 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0142157 |
| TXNRD1 | thioredoxin reductase 1 | -0.0142122 |
| TTLL7 | tubulin tyrosine ligase-like family member 7 | -0.0141811 |
| WDPCP | WD repeat containing planar cell polarity effector | -0.0141772 |
| ZFC3H1 | zinc finger, C3H1-type containing | -0.0141487 |
| RPL12 | ribosomal protein L12 | -0.0138909 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide | -0.0138757 |
| SESN3 | sestrin 3 | -0.013801 |
| RBL1 | retinoblastoma-like 1 | -0.0137204 |
| RPLP0 | ribosomal protein, large, P0 | -0.0136206 |
| UQCRC2 | ubiquinol-cytochrome c reductase core protein II | -0.0136101 |
| FOXP1 | forkhead box P1 | -0.0135773 |
| DDX39B | DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B | -0.0135397 |
| RPS29 | ribosomal protein S29 | -0.0135384 |
| RPL32 | ribosomal protein L32 | -0.013513 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | -0.0134385 |
| JMJD1C | jumonji domain containing 1C | -0.0134315 |
| EVI5 | ecotropic viral integration site 5 | -0.0132453 |
| SERGEF | secretion regulating guanine nucleotide exchange factor | -0.0131965 |
| STK38L | serine/threonine kinase 38 like | -0.013102 |
| USP15 | ubiquitin specific peptidase 15 | -0.0130971 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0130763 |
| BICC1 | BicC family RNA binding protein 1 | -0.013068 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | -0.012952 |
| COA1 | cytochrome c oxidase assembly factor 1 homolog (S. cerevisiae) | -0.0128293 |
