| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | L-Eflornithine (monohydrochloride) perturbation in hTERT-HPNE cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the L-Eflornithine (monohydrochloride)_hTERT-HPNE drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| INHBA | inhibin, beta A | 0.238406 |
| VIM | vimentin | 0.148191 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.142896 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.10579 |
| LOX | lysyl oxidase | 0.0780441 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0697164 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0695261 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0670376 |
| CALR | calreticulin | 0.0656398 |
| CALU | calumenin | 0.0641169 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0639434 |
| INSIG1 | insulin induced gene 1 | 0.0614119 |
| COL8A1 | collagen, type VIII, alpha 1 | 0.0612792 |
| VEGFA | vascular endothelial growth factor A | 0.0550811 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0548766 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0502298 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0501121 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0488711 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0486892 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0476397 |
| CANX | calnexin | 0.0471363 |
| MMP12 | matrix metallopeptidase 12 | 0.0465156 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0463239 |
| LDHA | lactate dehydrogenase A | 0.0462796 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0460865 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0454624 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0449757 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0433412 |
| YTHDC1 | YTH domain containing 1 | 0.0432472 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | 0.0428898 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0427686 |
| PDE8A | phosphodiesterase 8A | 0.0423617 |
| TMEM263 | transmembrane protein 263 | 0.0417484 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0417267 |
| NGLY1 | N-glycanase 1 | 0.0405859 |
| OGA | O-GlcNAcase | 0.0405073 |
| ZNF451 | zinc finger protein 451 | 0.0396705 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.038816 |
| UBC | ubiquitin C | 0.0382733 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0381524 |
| CLINT1 | clathrin interactor 1 | 0.0381417 |
| HMGB2 | high mobility group box 2 | 0.0374536 |
| ATP13A3 | ATPase type 13A3 | 0.0372937 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0366648 |
| SDC4 | syndecan 4 | 0.0366307 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0357767 |
| SGIP1 | SH3-domain GRB2-like (endophilin) interacting protein 1 | 0.0357746 |
| H1-0 | H1.0 linker histone | 0.0345238 |
| PDXDC1 | pyridoxal-dependent decarboxylase domain containing 1 | 0.0345192 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0340961 |
| CD44 | CD44 molecule (Indian blood group) | 0.0337428 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0335152 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0334467 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0330103 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | 0.0329784 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0329114 |
| TUBB | tubulin, beta class I | 0.0326958 |
| UBAP2L | ubiquitin associated protein 2-like | 0.0322851 |
| CUL3 | cullin 3 | 0.0319041 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.031183 |
| NUP98 | nucleoporin 98kDa | 0.0304084 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0301435 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.030081 |
| DNER | delta/notch-like EGF repeat containing | 0.029708 |
| RAI1 | retinoic acid induced 1 | 0.0294576 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0291589 |
| DUSP10 | dual specificity phosphatase 10 | 0.0288799 |
| HELZ | helicase with zinc finger | 0.0286307 |
| HLA-A | major histocompatibility complex, class I, A | 0.0285778 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0284058 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | 0.027885 |
| AP1G1 | adaptor-related protein complex 1, gamma 1 subunit | 0.0277387 |
| ARHGAP35 | Rho GTPase activating protein 35 | 0.0275024 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.027322 |
| COL1A2 | collagen, type I, alpha 2 | 0.0270999 |
| TBC1D23 | TBC1 domain family, member 23 | 0.0265849 |
| VCL | vinculin | 0.0265072 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0264526 |
| TRPC4 | transient receptor potential cation channel, subfamily C, member 4 | 0.026289 |
| SUCO | SUN domain containing ossification factor | 0.0261375 |
| SEPTIN9 | septin 9 | 0.0261102 |
| TMED10 | transmembrane emp24-like trafficking protein 10 (yeast) | 0.0260013 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0259884 |
| ADM | adrenomedullin | 0.0257835 |
| MCL1 | myeloid cell leukemia 1 | 0.0254417 |
| NR2F2 | nuclear receptor subfamily 2, group F, member 2 | 0.0253327 |
| HOOK3 | hook microtubule-tethering protein 3 | 0.0252777 |
| RPL3 | ribosomal protein L3 | 0.0252497 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0250034 |
| DIAPH1 | diaphanous-related formin 1 | 0.0248162 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0248142 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0248114 |
| COL6A2 | collagen, type VI, alpha 2 | 0.0241389 |
| SPAG9 | sperm associated antigen 9 | 0.0239528 |
| PGK1 | phosphoglycerate kinase 1 | 0.0238251 |
| AXL | AXL receptor tyrosine kinase | 0.0238095 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0237937 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0236949 |
| COG6 | component of oligomeric golgi complex 6 | 0.0236381 |
| APOLD1 | apolipoprotein L domain containing 1 | 0.0234676 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NALF1 | NALCN channel auxiliary factor 1 | -0.204275 |
| PRKG1 | protein kinase, cGMP-dependent, type I | -0.160427 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0991572 |
| NDRG1 | N-myc downstream regulated 1 | -0.0987578 |
| COL1A1 | collagen, type I, alpha 1 | -0.0858155 |
| ADAMTS12 | ADAM metallopeptidase with thrombospondin type 1 motif, 12 | -0.0734366 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0717978 |
| MT2A | metallothionein 2A | -0.0664656 |
| RPS6 | ribosomal protein S6 | -0.0657678 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0655345 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0651876 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0628468 |
| MYO10 | myosin X | -0.062671 |
| FRMD4A | FERM domain containing 4A | -0.0597936 |
| GLIS3 | GLIS family zinc finger 3 | -0.0594101 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0567071 |
| LOXL2 | lysyl oxidase-like 2 | -0.0520128 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.050839 |
| RPL37A | ribosomal protein L37a | -0.0507212 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0494873 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0480177 |
| RPL9 | ribosomal protein L9 | -0.0474845 |
| RAI14 | retinoic acid induced 14 | -0.0471795 |
| ZNF292 | zinc finger protein 292 | -0.0458406 |
| HMGA2 | high mobility group AT-hook 2 | -0.0453877 |
| RPS2 | ribosomal protein S2 | -0.0434015 |
| GREM1 | gremlin 1, DAN family BMP antagonist | -0.0427153 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0423514 |
| IER3 | immediate early response 3 | -0.0412982 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0411573 |
| NAV1 | neuron navigator 1 | -0.0410765 |
| RPL34 | ribosomal protein L34 | -0.0405452 |
| RPL19 | ribosomal protein L19 | -0.0398363 |
| FBN1 | fibrillin 1 | -0.0398105 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0397521 |
| ACTG1 | actin gamma 1 | -0.0386189 |
| HIPK2 | homeodomain interacting protein kinase 2 | -0.0385153 |
| CLMP | CXADR-like membrane protein | -0.0376685 |
| RFX8 | RFX family member 8, lacking RFX DNA binding domain | -0.0371806 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0356509 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | -0.0352189 |
| FOXP1 | forkhead box P1 | -0.0352153 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.0351993 |
| RPS12 | ribosomal protein S12 | -0.034583 |
| RPL11 | ribosomal protein L11 | -0.0345159 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0342257 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0328901 |
| RPL26 | ribosomal protein L26 | -0.0327735 |
| PRR16 | proline rich 16 | -0.0319438 |
| RPL38 | ribosomal protein L38 | -0.031789 |
| CCDC102B | coiled-coil domain containing 102B | -0.0314193 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.0307949 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0302509 |
| RPS8 | ribosomal protein S8 | -0.0297846 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.029759 |
| CDK6 | cyclin-dependent kinase 6 | -0.0297305 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.0292982 |
| CD59 | CD59 molecule, complement regulatory protein | -0.0291947 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0289153 |
| RPL5 | ribosomal protein L5 | -0.0288505 |
| MAP4 | microtubule-associated protein 4 | -0.0280661 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0280086 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.0279151 |
| SAMD3 | sterile alpha motif domain containing 3 | -0.0276548 |
| CCND1 | cyclin D1 | -0.0273289 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0272802 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.0272368 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | -0.027208 |
| JMJD1C | jumonji domain containing 1C | -0.0270842 |
| RPS16 | ribosomal protein S16 | -0.0270512 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0267437 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0265937 |
| KLF12 | Kruppel-like factor 12 | -0.0263069 |
| RPL35A | ribosomal protein L35a | -0.0261306 |
| PTK2 | protein tyrosine kinase 2 | -0.0253035 |
| RPL10A | ribosomal protein L10a | -0.0251387 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0250449 |
| CDH13 | cadherin 13 | -0.0248641 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0245127 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0244998 |
| SNX9 | sorting nexin 9 | -0.0243378 |
| GNG12 | guanine nucleotide binding protein (G protein), gamma 12 | -0.0243366 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0239878 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0239196 |
| DSTN | destrin (actin depolymerizing factor) | -0.0238235 |
| TAOK3 | TAO kinase 3 | -0.0233732 |
| KIAA1549L | KIAA1549-like | -0.0233154 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0231899 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0231004 |
| PCDH7 | protocadherin 7 | -0.0227795 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0226091 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0225922 |
| RPL30 | ribosomal protein L30 | -0.0225617 |
| GRIK5 | glutamate receptor, ionotropic, kainate 5 | -0.0224502 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | -0.022389 |
| RPS29 | ribosomal protein S29 | -0.0222854 |
| RPL7 | ribosomal protein L7 | -0.0220868 |
| MTSS1 | metastasis suppressor 1 | -0.0220844 |
| ASPH | aspartate beta-hydroxylase | -0.0220743 |
| RPS23 | ribosomal protein S23 | -0.0220095 |
