| Dataset | DeepCoverMOA Drug Mechanisms of Action |
| Category | proteomics |
| Type | drug perturbation |
| External Link | https://pubchem.ncbi.nlm.nih.gov/compound/16666 |
| Similar Terms | |
| Downloads & Tools |
197 proteins with high or low expression in L-Menthol relative to other proteins from the DeepCoverMOA Drug Mechanisms of Action dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NR1D2 | nuclear receptor subfamily 1, group D, member 2 | 1.54 |
| FN1 | fibronectin 1 | 0.78 |
| DOHH | deoxyhypusine hydroxylase/monooxygenase | 0.7 |
| NMNAT3 | nicotinamide nucleotide adenylyltransferase 3 | 0.7 |
| PEX19 | peroxisomal biogenesis factor 19 | 0.69 |
| HGH1 | HGH1 homolog (S. cerevisiae) | 0.67 |
| MYL3 | myosin, light chain 3, alkali; ventricular, skeletal, slow | 0.6 |
| PIP | prolactin-induced protein | 0.58 |
| ATP6V1F | ATPase, H+ transporting, lysosomal 14kDa, V1 subunit F | 0.56 |
| CLTA | clathrin, light chain A | 0.56 |
| SPC24 | SPC24, NDC80 kinetochore complex component | 0.56 |
| RPE | ribulose-5-phosphate-3-epimerase | 0.54 |
| NENF | neudesin neurotrophic factor | 0.52 |
| ANAPC16 | anaphase promoting complex subunit 16 | 0.52 |
| MCFD2 | multiple coagulation factor deficiency 2 | 0.5 |
| HSBP1 | heat shock factor binding protein 1 | 0.49 |
| NUCB1 | nucleobindin 1 | 0.48 |
| PPP1R2 | protein phosphatase 1, regulatory (inhibitor) subunit 2 | 0.48 |
| MXRA7 | matrix-remodelling associated 7 | 0.44 |
| CNTRL | centriolin | 0.44 |
| PPP1R2B | PPP1R2 family member B | 0.43 |
| BID | BH3 interacting domain death agonist | 0.42 |
| COA4 | cytochrome c oxidase assembly factor 4 homolog (S. cerevisiae) | 0.42 |
| TIGD5 | tigger transposable element derived 5 | 0.42 |
| MIEN1 | migration and invasion enhancer 1 | 0.41 |
| MKX | mohawk homeobox | 0.4 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.39 |
| POLR2J | polymerase (RNA) II (DNA directed) polypeptide J, 13.3kDa | 0.38 |
| C2CD3 | C2 calcium-dependent domain containing 3 | 0.38 |
| POLR2I | polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa | 0.37 |
| NDUFAB1 | NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1, 8kDa | 0.37 |
| ZNF268 | zinc finger protein 268 | 0.37 |
| KLHL15 | kelch-like family member 15 | 0.37 |
| N6AMT1 | N-6 adenine-specific DNA methyltransferase 1 (putative) | 0.36 |
| ZNF12 | zinc finger protein 12 | 0.35 |
| GON7 | GON7 subunit of KEOPS complex | 0.35 |
| ZNF263 | zinc finger protein 263 | 0.35 |
| CHCHD4 | coiled-coil-helix-coiled-coil-helix domain containing 4 | 0.34 |
| DIXDC1 | DIX domain containing 1 | 0.34 |
| GATC | glutamyl-tRNA(Gln) amidotransferase, subunit C | 0.34 |
| KIAA0825 | KIAA0825 | 0.34 |
| PFDN5 | prefoldin subunit 5 | 0.34 |
| SSNA1 | Sjogren syndrome nuclear autoantigen 1 | 0.34 |
| DCTPP1 | dCTP pyrophosphatase 1 | 0.33 |
| CIAO2B | cytosolic iron-sulfur assembly component 2B | 0.33 |
| CYB5A | cytochrome b5 type A (microsomal) | 0.32 |
| MAP3K12 | mitogen-activated protein kinase kinase kinase 12 | 0.32 |
| SBNO2 | strawberry notch homolog 2 (Drosophila) | 0.32 |
| TAF9B | TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa | 0.32 |
| LSM3 | LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae) | 0.32 |
| ASTE1 | asteroid homolog 1 (Drosophila) | 0.32 |
| METTL26 | methyltransferase like 26 | 0.32 |
| PFDN4 | prefoldin subunit 4 | 0.32 |
| FANCC | Fanconi anemia, complementation group C | 0.31 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | 0.31 |
| TICRR | TOPBP1-interacting checkpoint and replication regulator | 0.31 |
| CCDC91 | coiled-coil domain containing 91 | 0.31 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.31 |
| RPLP1 | ribosomal protein, large, P1 | 0.31 |
| TIMM8B | translocase of inner mitochondrial membrane 8 homolog B (yeast) | 0.31 |
| IQGAP2 | IQ motif containing GTPase activating protein 2 | 0.3 |
| SKP1 | S-phase kinase-associated protein 1 | 0.3 |
| HINT1 | histidine triad nucleotide binding protein 1 | 0.3 |
| SMAD1 | SMAD family member 1 | 0.3 |
| DCBLD1 | discoidin, CUB and LCCL domain containing 1 | 0.3 |
| HSP90AB3P | heat shock protein 90kDa alpha (cytosolic), class B member 3, pseudogene | 0.3 |
| PMF1 | polyamine-modulated factor 1 | 0.3 |
| MARK4 | MAP/microtubule affinity-regulating kinase 4 | 0.29 |
| PSRC1 | proline/serine-rich coiled-coil 1 | 0.29 |
| ARL14EP | ADP-ribosylation factor-like 14 effector protein | 0.29 |
| DIABLO | diablo, IAP-binding mitochondrial protein | 0.29 |
| AKNA | AT-hook transcription factor | 0.29 |
| POLQ | polymerase (DNA directed), theta | 0.29 |
| S100A2 | S100 calcium binding protein A2 | 0.29 |
| CDC37L1 | cell division cycle 37-like 1 | 0.29 |
| PEX5 | peroxisomal biogenesis factor 5 | 0.29 |
| COMMD9 | COMM domain containing 9 | 0.28 |
| ATP5PF | ATP synthase peripheral stalk subunit F6 | 0.28 |
| DNAJC24 | DnaJ (Hsp40) homolog, subfamily C, member 24 | 0.28 |
| SPTB | spectrin, beta, erythrocytic | 0.28 |
| TXN2 | thioredoxin 2 | 0.28 |
| CCSER2 | coiled-coil serine-rich protein 2 | 0.28 |
| MYCBP | MYC binding protein | 0.28 |
| GINS4 | GINS complex subunit 4 (Sld5 homolog) | 0.27 |
| UQCRH | ubiquinol-cytochrome c reductase hinge protein | 0.27 |
| CHST7 | carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7 | 0.27 |
| SS18L1 | synovial sarcoma translocation gene on chromosome 18-like 1 | 0.27 |
| DBI | diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein) | 0.27 |
| CCDC85B | coiled-coil domain containing 85B | 0.27 |
| ARHGEF35 | Rho guanine nucleotide exchange factor (GEF) 35 | 0.27 |
| ZNF100 | zinc finger protein 100 | 0.27 |
| COMMD8 | COMM domain containing 8 | 0.27 |
| SERF2 | small EDRK-rich factor 2 | 0.27 |
| SIRPA | signal-regulatory protein alpha | 0.27 |
| ASIC1 | acid sensing (proton gated) ion channel 1 | 0.27 |
| LIPE | lipase, hormone-sensitive | 0.27 |
| ATXN7L2 | ataxin 7-like 2 | 0.26 |
| ARMC7 | armadillo repeat containing 7 | 0.26 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SGSH | N-sulfoglucosamine sulfohydrolase | -1.05 |
| PCBD1 | pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha | -0.9 |
| CD58 | CD58 molecule | -0.63 |
| DDN | dendrin | -0.62 |
| ZCCHC14 | zinc finger, CCHC domain containing 14 | -0.51 |
| COX10 | COX10 heme A:farnesyltransferase cytochrome c oxidase assembly factor | -0.47 |
| MKS1 | Meckel syndrome, type 1 | -0.46 |
| TMEM159 | transmembrane protein 159 | -0.44 |
| PRG4 | proteoglycan 4 | -0.41 |
| ARHGEF37 | Rho guanine nucleotide exchange factor (GEF) 37 | -0.41 |
| NIPSNAP3A | nipsnap homolog 3A (C. elegans) | -0.41 |
| RCAN3 | RCAN family member 3 | -0.4 |
| FUT10 | fucosyltransferase 10 (alpha (1,3) fucosyltransferase) | -0.39 |
| TMEM41B | transmembrane protein 41B | -0.38 |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase | -0.37 |
| ATP6V0A1 | ATPase, H+ transporting, lysosomal V0 subunit a1 | -0.37 |
| CTHRC1 | collagen triple helix repeat containing 1 | -0.37 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.36 |
| ZNF566 | zinc finger protein 566 | -0.36 |
| PRRG1 | proline rich Gla (G-carboxyglutamic acid) 1 | -0.35 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.35 |
| DNAJC30 | DnaJ (Hsp40) homolog, subfamily C, member 30 | -0.35 |
| WWC2 | WW and C2 domain containing 2 | -0.35 |
| OTC | ornithine carbamoyltransferase | -0.34 |
| CCDC57 | coiled-coil domain containing 57 | -0.34 |
| ZXDB | zinc finger, X-linked, duplicated B | -0.33 |
| TEP1 | telomerase-associated protein 1 | -0.33 |
| DHRS13 | dehydrogenase/reductase (SDR family) member 13 | -0.33 |
| LMLN | leishmanolysin-like (metallopeptidase M8 family) | -0.33 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.33 |
| AMACR | alpha-methylacyl-CoA racemase | -0.32 |
| HNF4A | hepatocyte nuclear factor 4, alpha | -0.32 |
| CPA4 | carboxypeptidase A4 | -0.31 |
| TNFRSF1A | tumor necrosis factor receptor superfamily, member 1A | -0.31 |
| METTL22 | methyltransferase like 22 | -0.3 |
| TM7SF2 | transmembrane 7 superfamily member 2 | -0.3 |
| KLHL17 | kelch-like family member 17 | -0.3 |
| MLLT6 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6 | -0.3 |
| LETMD1 | LETM1 domain containing 1 | -0.29 |
| RELT | RELT tumor necrosis factor receptor | -0.29 |
| ARID3A | AT rich interactive domain 3A (BRIGHT-like) | -0.29 |
| AASS | aminoadipate-semialdehyde synthase | -0.29 |
| RHOQ | ras homolog family member Q | -0.28 |
| SGCE | sarcoglycan, epsilon | -0.28 |
| DAP | death-associated protein | -0.27 |
| TAB3 | TGF-beta activated kinase 1/MAP3K7 binding protein 3 | -0.27 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.27 |
| UQCC2 | ubiquinol-cytochrome c reductase complex assembly factor 2 | -0.26 |
| CNNM1 | cyclin and CBS domain divalent metal cation transport mediator 1 | -0.26 |
| TM7SF3 | transmembrane 7 superfamily member 3 | -0.26 |
| XRCC5 | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) | -0.26 |
| BRD3 | bromodomain containing 3 | -0.26 |
| C4BPA | complement component 4 binding protein, alpha | -0.26 |
| RHOD | ras homolog family member D | -0.26 |
| MYADM | myeloid-associated differentiation marker | -0.26 |
| ARHGAP44 | Rho GTPase activating protein 44 | -0.26 |
| AMMECR1L | AMMECR1-like | -0.25 |
| ENO1 | enolase 1, (alpha) | -0.25 |
| TFAP2C | transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) | -0.25 |
| MPV17 | MpV17 mitochondrial inner membrane protein | -0.25 |
| MLXIPL | MLX interacting protein-like | -0.25 |
| SNX16 | sorting nexin 16 | -0.25 |
| GRK5 | G protein-coupled receptor kinase 5 | -0.24 |
| BCDIN3D | BCDIN3 domain containing | -0.24 |
| CCDC77 | coiled-coil domain containing 77 | -0.24 |
| LPIN3 | lipin 3 | -0.24 |
| CDC42EP2 | CDC42 effector protein (Rho GTPase binding) 2 | -0.24 |
| HDIP1 | HDAC and MIER1 interacting protein 1 | -0.24 |
| KIRREL1 | kirre like nephrin family adhesion molecule 1 | -0.23 |
| ROGDI | rogdi homolog (Drosophila) | -0.23 |
| C1QTNF3 | C1q and tumor necrosis factor related protein 3 | -0.23 |
| ENTPD5 | ectonucleoside triphosphate diphosphohydrolase 5 | -0.23 |
| PCNX1 | pecanex 1 | -0.23 |
| LAPTM4A | lysosomal protein transmembrane 4 alpha | -0.23 |
| MSL2 | male-specific lethal 2 homolog (Drosophila) | -0.23 |
| AP4S1 | adaptor-related protein complex 4, sigma 1 subunit | -0.23 |
| STX17 | syntaxin 17 | -0.23 |
| FOXM1 | forkhead box M1 | -0.23 |
| TSPAN15 | tetraspanin 15 | -0.22 |
| APOBEC3G | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G | -0.22 |
| TMEM179B | transmembrane protein 179B | -0.22 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | -0.22 |
| NDRG1 | N-myc downstream regulated 1 | -0.22 |
| BTBD11 | BTB (POZ) domain containing 11 | -0.22 |
| ADCK1 | aarF domain containing kinase 1 | -0.22 |
| DZIP3 | DAZ interacting zinc finger protein 3 | -0.22 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.22 |
| SORBS1 | sorbin and SH3 domain containing 1 | -0.21 |
| PRDM16 | PR domain containing 16 | -0.21 |
| CLN3 | ceroid-lipofuscinosis, neuronal 3 | -0.21 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.21 |
| FAM124A | family with sequence similarity 124A | -0.21 |
| GSR | glutathione reductase | -0.21 |
| NHSL1 | NHS-like 1 | -0.21 |
| FAM171A2 | family with sequence similarity 171, member A2 | -0.21 |
| AKT1S1 | AKT1 substrate 1 (proline-rich) | -0.2 |
| KCNN4 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 | -0.2 |
| ELFN2 | extracellular leucine-rich repeat and fibronectin type III domain containing 2 | -0.2 |
| ING4 | inhibitor of growth family, member 4 | -0.2 |
