| Dataset | DeepCoverMOA Drug Mechanisms of Action |
| Category | proteomics |
| Type | drug perturbation |
| External Link | https://pubchem.ncbi.nlm.nih.gov/compound/440473 |
| Similar Terms | |
| Downloads & Tools |
197 proteins with high or low expression in L-Mimosine relative to other proteins from the DeepCoverMOA Drug Mechanisms of Action dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | 1.98 |
| KMT2B | lysine (K)-specific methyltransferase 2B | 1.28 |
| F13A1 | coagulation factor XIII, A1 polypeptide | 1.04 |
| PREX1 | phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1 | 0.94 |
| PYGM | phosphorylase, glycogen, muscle | 0.74 |
| MYH2 | myosin, heavy chain 2, skeletal muscle, adult | 0.74 |
| CTNND2 | catenin (cadherin-associated protein), delta 2 | 0.57 |
| COPZ1 | coatomer protein complex, subunit zeta 1 | 0.46 |
| TPST2 | tyrosylprotein sulfotransferase 2 | 0.45 |
| TNFRSF1A | tumor necrosis factor receptor superfamily, member 1A | 0.44 |
| SERF2 | small EDRK-rich factor 2 | 0.42 |
| RCBTB1 | regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1 | 0.4 |
| N6AMT1 | N-6 adenine-specific DNA methyltransferase 1 (putative) | 0.4 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.39 |
| BTBD11 | BTB (POZ) domain containing 11 | 0.36 |
| ECHDC3 | enoyl CoA hydratase domain containing 3 | 0.34 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | 0.34 |
| RCAN3 | RCAN family member 3 | 0.34 |
| PARP3 | poly (ADP-ribose) polymerase family, member 3 | 0.33 |
| PMS1 | PMS1 postmeiotic segregation increased 1 (S. cerevisiae) | 0.33 |
| METTL26 | methyltransferase like 26 | 0.32 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.32 |
| DST | dystonin | 0.32 |
| COMMD8 | COMM domain containing 8 | 0.32 |
| PRKX | protein kinase, X-linked | 0.31 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | 0.31 |
| IFT22 | intraflagellar transport 22 | 0.3 |
| TIGD5 | tigger transposable element derived 5 | 0.3 |
| FGFR1 | fibroblast growth factor receptor 1 | 0.29 |
| GINS4 | GINS complex subunit 4 (Sld5 homolog) | 0.29 |
| SPC24 | SPC24, NDC80 kinetochore complex component | 0.29 |
| BRK1 | BRICK1, SCAR/WAVE actin-nucleating complex subunit | 0.28 |
| RILPL2 | Rab interacting lysosomal protein-like 2 | 0.27 |
| CCDC170 | coiled-coil domain containing 170 | 0.27 |
| CCND3 | cyclin D3 | 0.27 |
| PRR3 | proline rich 3 | 0.26 |
| ZNF552 | zinc finger protein 552 | 0.26 |
| NFU1 | NFU1 iron-sulfur cluster scaffold | 0.26 |
| LGALSL | lectin, galactoside-binding-like | 0.26 |
| PTMA | prothymosin, alpha | 0.26 |
| SYAP1 | synapse associated protein 1 | 0.26 |
| ZNF799 | zinc finger protein 799 | 0.26 |
| SLC26A2 | solute carrier family 26 (anion exchanger), member 2 | 0.26 |
| UCHL5 | ubiquitin carboxyl-terminal hydrolase L5 | 0.26 |
| MARK2 | MAP/microtubule affinity-regulating kinase 2 | 0.26 |
| MYLK | myosin light chain kinase | 0.26 |
| UBE2A | ubiquitin-conjugating enzyme E2A | 0.25 |
| RABEP2 | rabaptin, RAB GTPase binding effector protein 2 | 0.25 |
| ZNF76 | zinc finger protein 76 | 0.25 |
| CLTA | clathrin, light chain A | 0.25 |
| GRID1 | glutamate receptor, ionotropic, delta 1 | 0.25 |
| FAM171A2 | family with sequence similarity 171, member A2 | 0.25 |
| MIEN1 | migration and invasion enhancer 1 | 0.25 |
| EIF3K | eukaryotic translation initiation factor 3, subunit K | 0.25 |
| GPRC5B | G protein-coupled receptor, class C, group 5, member B | 0.25 |
| PAFAH1B2 | platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa) | 0.25 |
| SKP1 | S-phase kinase-associated protein 1 | 0.24 |
| TNFAIP1 | tumor necrosis factor, alpha-induced protein 1 (endothelial) | 0.24 |
| AKNA | AT-hook transcription factor | 0.24 |
| DIXDC1 | DIX domain containing 1 | 0.24 |
| SLC10A4 | solute carrier family 10, member 4 | 0.24 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.24 |
| RPS15 | ribosomal protein S15 | 0.24 |
| RPLP1 | ribosomal protein, large, P1 | 0.24 |
| NUTF2 | nuclear transport factor 2 | 0.23 |
| PGRMC1 | progesterone receptor membrane component 1 | 0.23 |
| FBXO44 | F-box protein 44 | 0.23 |
| UQCRH | ubiquinol-cytochrome c reductase hinge protein | 0.23 |
| CSTF2 | cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa | 0.23 |
| CCSER2 | coiled-coil serine-rich protein 2 | 0.23 |
| FDX1 | ferredoxin 1 | 0.23 |
| MARK4 | MAP/microtubule affinity-regulating kinase 4 | 0.23 |
| FBXL3 | F-box and leucine-rich repeat protein 3 | 0.22 |
| CHCHD4 | coiled-coil-helix-coiled-coil-helix domain containing 4 | 0.22 |
| ELOB | elongin B | 0.22 |
| LSM3 | LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae) | 0.22 |
| HGH1 | HGH1 homolog (S. cerevisiae) | 0.22 |
| COMMD3 | COMM domain containing 3 | 0.22 |
| NAXE | NAD(P)HX epimerase | 0.22 |
| DNAH9 | dynein, axonemal, heavy chain 9 | 0.22 |
| SGTA | small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha | 0.22 |
| TTN | titin | 0.22 |
| PDE4DIP | phosphodiesterase 4D interacting protein | 0.22 |
| AAGAB | alpha- and gamma-adaptin binding protein | 0.22 |
| UBE2W | ubiquitin-conjugating enzyme E2W (putative) | 0.22 |
| FAM126B | family with sequence similarity 126, member B | 0.21 |
| ZBTB49 | zinc finger and BTB domain containing 49 | 0.21 |
| ZNF200 | zinc finger protein 200 | 0.21 |
| SP100 | SP100 nuclear antigen | 0.21 |
| ISCA2 | iron-sulfur cluster assembly 2 | 0.21 |
| MLLT3 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 | 0.21 |
| RPL26 | ribosomal protein L26 | 0.21 |
| CDC7 | cell division cycle 7 | 0.21 |
| UBQLN1 | ubiquilin 1 | 0.21 |
| RARG | retinoic acid receptor, gamma | 0.21 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.21 |
| UBE2L6 | ubiquitin-conjugating enzyme E2L 6 | 0.21 |
| ZC3H14 | zinc finger CCCH-type containing 14 | 0.21 |
| ALKBH7 | alkB, alkylation repair homolog 7 (E. coli) | 0.2 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LMOD1 | leiomodin 1 (smooth muscle) | -1.89 |
| PCBD1 | pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha | -1.05 |
| KLHL29 | kelch-like family member 29 | -0.99 |
| ADCY10 | adenylate cyclase 10 (soluble) | -0.76 |
| KIAA1210 | KIAA1210 | -0.69 |
| ENPP1 | ectonucleotide pyrophosphatase/phosphodiesterase 1 | -0.63 |
| PAH | phenylalanine hydroxylase | -0.6 |
| PIP | prolactin-induced protein | -0.59 |
| NRBF2 | nuclear receptor binding factor 2 | -0.59 |
| TTLL4 | tubulin tyrosine ligase-like family member 4 | -0.58 |
| TFDP2 | transcription factor Dp-2 (E2F dimerization partner 2) | -0.55 |
| SLC22A18 | solute carrier family 22, member 18 | -0.55 |
| SGSH | N-sulfoglucosamine sulfohydrolase | -0.54 |
| TCEA2 | transcription elongation factor A (SII), 2 | -0.53 |
| C4BPA | complement component 4 binding protein, alpha | -0.51 |
| DAP | death-associated protein | -0.51 |
| SERINC5 | serine incorporator 5 | -0.5 |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) | -0.49 |
| MRC2 | mannose receptor, C type 2 | -0.49 |
| CD58 | CD58 molecule | -0.48 |
| NRP1 | neuropilin 1 | -0.48 |
| WWOX | WW domain containing oxidoreductase | -0.47 |
| TM7SF3 | transmembrane 7 superfamily member 3 | -0.47 |
| PRG4 | proteoglycan 4 | -0.47 |
| OASL | 2'-5'-oligoadenylate synthetase-like | -0.46 |
| C15ORF41 | chromosome 15 open reading frame 41 | -0.46 |
| KIAA0825 | KIAA0825 | -0.44 |
| NIPSNAP3A | nipsnap homolog 3A (C. elegans) | -0.43 |
| TMEM59 | transmembrane protein 59 | -0.42 |
| ACE | angiotensin I converting enzyme | -0.42 |
| ZNF12 | zinc finger protein 12 | -0.41 |
| ELOVL6 | ELOVL fatty acid elongase 6 | -0.41 |
| PPIE | peptidylprolyl isomerase E (cyclophilin E) | -0.4 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.4 |
| SDR16C5 | short chain dehydrogenase/reductase family 16C, member 5 | -0.39 |
| FAM8A1 | family with sequence similarity 8, member A1 | -0.39 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | -0.39 |
| EVA1C | eva-1 homolog C (C. elegans) | -0.39 |
| CHRD | chordin | -0.38 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.37 |
| NRBP2 | nuclear receptor binding protein 2 | -0.36 |
| PLPP3 | phospholipid phosphatase 3 | -0.36 |
| ZG16B | zymogen granule protein 16B | -0.36 |
| TOR2A | torsin family 2, member A | -0.35 |
| ZXDB | zinc finger, X-linked, duplicated B | -0.35 |
| SLC25A44 | solute carrier family 25, member 44 | -0.35 |
| SHFL | shiftless antiviral inhibitor of ribosomal frameshifting | -0.34 |
| FAM171B | family with sequence similarity 171, member B | -0.34 |
| SS18L1 | synovial sarcoma translocation gene on chromosome 18-like 1 | -0.34 |
| GMEB2 | glucocorticoid modulatory element binding protein 2 | -0.34 |
| NCKAP5L | NCK-associated protein 5-like | -0.33 |
| TSSC4 | tumor suppressing subtransferable candidate 4 | -0.33 |
| APOE | apolipoprotein E | -0.33 |
| MT-ND5 | NADH dehydrogenase, subunit 5 (complex I) | -0.33 |
| FAM122A | family with sequence similarity 122A | -0.33 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.33 |
| ACVR2A | activin A receptor, type IIA | -0.33 |
| TLE1 | transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) | -0.32 |
| FBXO41 | F-box protein 41 | -0.32 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | -0.32 |
| MEGF8 | multiple EGF-like-domains 8 | -0.32 |
| NPHP1 | nephronophthisis 1 (juvenile) | -0.32 |
| MCTP2 | multiple C2 domains, transmembrane 2 | -0.32 |
| LTN1 | listerin E3 ubiquitin protein ligase 1 | -0.32 |
| ENO1 | enolase 1, (alpha) | -0.32 |
| ARG2 | arginase 2 | -0.31 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.31 |
| CPA4 | carboxypeptidase A4 | -0.31 |
| KLF4 | Kruppel-like factor 4 (gut) | -0.3 |
| ADIRF | adipogenesis regulatory factor | -0.3 |
| MAX | MYC associated factor X | -0.3 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.3 |
| SNRPC | small nuclear ribonucleoprotein polypeptide C | -0.3 |
| DNAJC30 | DnaJ (Hsp40) homolog, subfamily C, member 30 | -0.29 |
| PRRG1 | proline rich Gla (G-carboxyglutamic acid) 1 | -0.29 |
| NDRG1 | N-myc downstream regulated 1 | -0.29 |
| MT1X | metallothionein 1X | -0.29 |
| PPP1R11 | protein phosphatase 1, regulatory (inhibitor) subunit 11 | -0.29 |
| DHRSX | dehydrogenase/reductase (SDR family) X-linked | -0.29 |
| NEMP1 | nuclear envelope integral membrane protein 1 | -0.29 |
| DYNLT3 | dynein, light chain, Tctex-type 3 | -0.29 |
| SLC25A38 | solute carrier family 25, member 38 | -0.29 |
| CDC26 | cell division cycle 26 | -0.28 |
| RNF111 | ring finger protein 111 | -0.28 |
| JUN | jun proto-oncogene | -0.28 |
| EML3 | echinoderm microtubule associated protein like 3 | -0.28 |
| COL14A1 | collagen, type XIV, alpha 1 | -0.28 |
| ITM2C | integral membrane protein 2C | -0.28 |
| LPIN1 | lipin 1 | -0.27 |
| ARHGEF35 | Rho guanine nucleotide exchange factor (GEF) 35 | -0.27 |
| GLT8D2 | glycosyltransferase 8 domain containing 2 | -0.27 |
| PCGF3 | polycomb group ring finger 3 | -0.27 |
| KLHL25 | kelch-like family member 25 | -0.27 |
| DCLRE1B | DNA cross-link repair 1B | -0.27 |
| ZNF189 | zinc finger protein 189 | -0.27 |
| TPM1 | tropomyosin 1 (alpha) | -0.27 |
| COX11 | COX11 cytochrome c oxidase copper chaperone | -0.27 |
| CEP104 | centrosomal protein 104kDa | -0.27 |
