L-Proline Gene Set
Dataset
DrugBank Drug Targets
Category
physical interactions
Type
drug
Description
Pyrrolidine in which the pro-S hydrogen at position 2 is substituted by a carboxylic acid group. L-Proline is the only one of the twenty DNA-encoded amino acids which has a secondary amino group alpha to the carboxyl group. It is an essential component of collagen and is important for proper functioning of joints and tendons. It also helps maintain and strengthen heart muscles. (Chemical Entities of Biological Interest Ontology , CHEBI_17203 )
External Link
http://www.drugbank.ca/drugs/DB00172
Similar Terms
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Genes
22 interacting proteins for the L-Proline drug from the curated DrugBank Drug Targets dataset.
Symbol
Name
EPRS
glutamyl-prolyl-tRNA synthetase
L3HYPDH
L-3-hydroxyproline dehydratase (trans-)
P3H1
prolyl 3-hydroxylase 1
P3H2
prolyl 3-hydroxylase 2
P3H3
prolyl 3-hydroxylase 3
P4HA1
prolyl 4-hydroxylase, alpha polypeptide I
P4HA2
prolyl 4-hydroxylase, alpha polypeptide II
PARS2
prolyl-tRNA synthetase 2, mitochondrial (putative)
PPIA
peptidylprolyl isomerase A (cyclophilin A)
PPIB
peptidylprolyl isomerase B (cyclophilin B)
PPIC
peptidylprolyl isomerase C (cyclophilin C)
PPIF
peptidylprolyl isomerase F
PPIG
peptidylprolyl isomerase G (cyclophilin G)
PPIH
peptidylprolyl isomerase H (cyclophilin H)
PRODH
proline dehydrogenase (oxidase) 1
PROSC
proline synthetase co-transcribed homolog (bacterial)
PYCR1
pyrroline-5-carboxylate reductase 1
PYCR2
pyrroline-5-carboxylate reductase family, member 2
PYCRL
pyrroline-5-carboxylate reductase-like
SLC16A10
solute carrier family 16 (aromatic amino acid transporter), member 10
SLC6A14
solute carrier family 6 (amino acid transporter), member 14
SLC6A7
solute carrier family 6 (neurotransmitter transporter), member 7
