L-Proline Gene Set

Dataset HMDB Metabolites of Enzymes
Category physical interactions
Type metabolite
Description Pyrrolidine in which the pro-S hydrogen at position 2 is substituted by a carboxylic acid group. L-Proline is the only one of the twenty DNA-encoded amino acids which has a secondary amino group alpha to the carboxyl group. It is an essential component of collagen and is important for proper functioning of joints and tendons. It also helps maintain and strengthen heart muscles. (Chemical Entities of Biological Interest Ontology, CHEBI_17203)
External Link http://www.hmdb.ca/metabolites/HMDB00162
Similar Terms
Downloads & Tools

Genes

29 interacting proteins for the L-Proline metabolite from the curated HMDB Metabolites of Enzymes dataset.

Symbol Name
EGLN1 egl-9 family hypoxia-inducible factor 1
EGLN2 egl-9 family hypoxia-inducible factor 2
EGLN3 egl-9 family hypoxia-inducible factor 3
EPRS glutamyl-prolyl-tRNA synthetase
L3HYPDH L-3-hydroxyproline dehydratase (trans-)
LAP3 leucine aminopeptidase 3
P3H1 prolyl 3-hydroxylase 1
P3H2 prolyl 3-hydroxylase 2
P3H3 prolyl 3-hydroxylase 3
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II
P4HA3 prolyl 4-hydroxylase, alpha polypeptide III
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
PARS2 prolyl-tRNA synthetase 2, mitochondrial (putative)
PPIA peptidylprolyl isomerase A (cyclophilin A)
PPIB peptidylprolyl isomerase B (cyclophilin B)
PPIF peptidylprolyl isomerase F
PPIG peptidylprolyl isomerase G (cyclophilin G)
PPIH peptidylprolyl isomerase H (cyclophilin H)
PRODH proline dehydrogenase (oxidase) 1
PRODH2 proline dehydrogenase (oxidase) 2
PROSC proline synthetase co-transcribed homolog (bacterial)
PYCR1 pyrroline-5-carboxylate reductase 1
PYCR2 pyrroline-5-carboxylate reductase family, member 2
PYCRL pyrroline-5-carboxylate reductase-like
SLC16A10 solute carrier family 16 (aromatic amino acid transporter), member 10
SLC6A14 solute carrier family 6 (amino acid transporter), member 14
SLC6A7 solute carrier family 6 (neurotransmitter transporter), member 7
TRPM1 transient receptor potential cation channel, subfamily M, member 1