| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | L-Thyroxine (sodium salt pentahydrate) perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the L-Thyroxine (sodium salt pentahydrate)_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TRIO | trio Rho guanine nucleotide exchange factor | 0.15771 |
| PODXL | podocalyxin-like | 0.148021 |
| CDH13 | cadherin 13 | 0.139791 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.105159 |
| COL5A1 | collagen, type V, alpha 1 | 0.0828534 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 | 0.0749833 |
| SLC39A11 | solute carrier family 39, member 11 | 0.0745295 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0683675 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0676286 |
| CENPF | centromere protein F, 350/400kDa | 0.0587015 |
| EGFR | epidermal growth factor receptor | 0.0583697 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0571504 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0543665 |
| MAP1B | microtubule-associated protein 1B | 0.0540912 |
| POTEF | POTE ankyrin domain family, member F | 0.0540418 |
| EFNA5 | ephrin-A5 | 0.0533214 |
| TPM4 | tropomyosin 4 | 0.0528251 |
| MT2A | metallothionein 2A | 0.0518877 |
| ASPH | aspartate beta-hydroxylase | 0.0514985 |
| MSN | moesin | 0.0513203 |
| FSTL1 | follistatin-like 1 | 0.0497178 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.048467 |
| DGKG | diacylglycerol kinase, gamma 90kDa | 0.0481698 |
| TPM3 | tropomyosin 3 | 0.0473324 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0470833 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0467941 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.046469 |
| NAV1 | neuron navigator 1 | 0.0462015 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0461928 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0457416 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0455733 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0450359 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0448436 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0442753 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0422192 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | 0.042076 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0420192 |
| FLNB | filamin B, beta | 0.0417419 |
| RPS2 | ribosomal protein S2 | 0.0416405 |
| PRKAG2 | protein kinase, AMP-activated, gamma 2 non-catalytic subunit | 0.0405448 |
| CSTB | cystatin B (stefin B) | 0.0395316 |
| FAM107B | family with sequence similarity 107, member B | 0.0391068 |
| NAV2 | neuron navigator 2 | 0.0388504 |
| DSPP | dentin sialophosphoprotein | 0.0388201 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0383383 |
| CYTH3 | cytohesin 3 | 0.0383099 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | 0.0382562 |
| RPL37A | ribosomal protein L37a | 0.0379981 |
| SEPTIN9 | septin 9 | 0.0373046 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.037109 |
| LMNA | lamin A/C | 0.0366495 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | 0.0365922 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0364377 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0344561 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0338722 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0333426 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0330887 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0330546 |
| PLXNA2 | plexin A2 | 0.0324736 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0323825 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0322602 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0321276 |
| FLT1 | fms-related tyrosine kinase 1 | 0.0319763 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.0312795 |
| SYTL3 | synaptotagmin-like 3 | 0.0307499 |
| NDRG1 | N-myc downstream regulated 1 | 0.0307033 |
| SH3BP5 | SH3-domain binding protein 5 (BTK-associated) | 0.0301843 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | 0.0299838 |
| CEP170 | centrosomal protein 170kDa | 0.0298604 |
| ANO6 | anoctamin 6 | 0.0297676 |
| MYOF | myoferlin | 0.0294744 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0286361 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | 0.0286227 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.0282345 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | 0.0274221 |
| HDAC9 | histone deacetylase 9 | 0.0270518 |
| RAB11FIP3 | RAB11 family interacting protein 3 (class II) | 0.0268227 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.02674 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0266601 |
| SPDL1 | spindle apparatus coiled-coil protein 1 | 0.0264159 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0258213 |
| VEGFA | vascular endothelial growth factor A | 0.0257112 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0253256 |
| FN1 | fibronectin 1 | 0.0251864 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0251838 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0251083 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0248656 |
| MTCL1 | microtubule crosslinking factor 1 | 0.0247723 |
| ERBIN | erbb2 interacting protein | 0.0246581 |
| ENO1 | enolase 1, (alpha) | 0.0244248 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0243297 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0242803 |
| LAMC2 | laminin, gamma 2 | 0.0241383 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | 0.023978 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0237702 |
| HS3ST3A1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 | 0.0236977 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0236659 |
| CALR | calreticulin | 0.0233683 |
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase | 0.0233188 |
| FARP1 | FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) | 0.0231721 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FBN1 | fibrillin 1 | -0.23438 |
| LOX | lysyl oxidase | -0.153136 |
| COL1A2 | collagen, type I, alpha 2 | -0.129656 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.121776 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.118597 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.115702 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.106659 |
| VIM | vimentin | -0.104384 |
| TMSB10 | thymosin beta 10 | -0.0912897 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0862836 |
| UBC | ubiquitin C | -0.0792777 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0775986 |
| COL5A2 | collagen, type V, alpha 2 | -0.0734442 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0716289 |
| AHNAK | AHNAK nucleoprotein | -0.0697684 |
| COL3A1 | collagen, type III, alpha 1 | -0.0621474 |
| DPYSL3 | dihydropyrimidinase-like 3 | -0.0587253 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0557977 |
| MX2 | MX dynamin-like GTPase 2 | -0.05402 |
| AUTS2 | autism susceptibility candidate 2 | -0.0535099 |
| THBS2 | thrombospondin 2 | -0.053147 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0522072 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0498808 |
| ANXA2 | annexin A2 | -0.0493816 |
| GPC6 | glypican 6 | -0.0475655 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0453845 |
| HLA-B | major histocompatibility complex, class I, B | -0.0453306 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0451223 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0448499 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0436399 |
| FRMD5 | FERM domain containing 5 | -0.0414461 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0409546 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.03946 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0391439 |
| ARL15 | ADP-ribosylation factor-like 15 | -0.0381114 |
| MEIS2 | Meis homeobox 2 | -0.0377632 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0368308 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0362455 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0347711 |
| HLA-E | major histocompatibility complex, class I, E | -0.0346127 |
| TUBB | tubulin, beta class I | -0.0345276 |
| SQSTM1 | sequestosome 1 | -0.0333563 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | -0.033023 |
| SAMD9L | sterile alpha motif domain containing 9-like | -0.0320359 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.031549 |
| KIFAP3 | kinesin-associated protein 3 | -0.0309823 |
| GLIS3 | GLIS family zinc finger 3 | -0.0302294 |
| VCL | vinculin | -0.0301366 |
| SBF2 | SET binding factor 2 | -0.0299624 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | -0.0297939 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0295042 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0293903 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0281219 |
| WDFY1 | WD repeat and FYVE domain containing 1 | -0.0274115 |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) | -0.0273707 |
| PGK1 | phosphoglycerate kinase 1 | -0.0272896 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0271863 |
| ANKRD10 | ankyrin repeat domain 10 | -0.027042 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0269547 |
| WTAP | Wilms tumor 1 associated protein | -0.0260465 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0260217 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0258086 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0255562 |
| SOX9 | SRY (sex determining region Y)-box 9 | -0.0255199 |
| TRIM22 | tripartite motif containing 22 | -0.0255097 |
| PXDN | peroxidasin | -0.025411 |
| IER3 | immediate early response 3 | -0.0253712 |
| DST | dystonin | -0.0247303 |
| TMEM123 | transmembrane protein 123 | -0.0242936 |
| EHBP1 | EH domain binding protein 1 | -0.0240801 |
| CD99 | CD99 molecule | -0.0234813 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0230014 |
| ACTN4 | actinin, alpha 4 | -0.0229501 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0228251 |
| PRRX1 | paired related homeobox 1 | -0.0223408 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0223049 |
| TDRD7 | tudor domain containing 7 | -0.0221463 |
| TMOD1 | tropomodulin 1 | -0.0221346 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0221227 |
| ATP13A3 | ATPase type 13A3 | -0.0221176 |
| GPBP1 | GC-rich promoter binding protein 1 | -0.0221167 |
| EPAS1 | endothelial PAS domain protein 1 | -0.021521 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0214425 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.0213799 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0211714 |
| IRF1 | interferon regulatory factor 1 | -0.0211586 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0211529 |
| DENND5A | DENN/MADD domain containing 5A | -0.0211461 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0210765 |
| TXNIP | thioredoxin interacting protein | -0.0209234 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.020815 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0207329 |
| YME1L1 | YME1-like 1 ATPase | -0.0207293 |
| SVIL | supervillin | -0.0206007 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0205198 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0204116 |
| ZNF207 | zinc finger protein 207 | -0.0203828 |
| BSG | basigin (Ok blood group) | -0.0201936 |
| MAP4 | microtubule-associated protein 4 | -0.0201812 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0201741 |
