| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | L-Thyroxine (sodium salt pentahydrate) perturbation in AsPC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the L-Thyroxine (sodium salt pentahydrate)_AsPC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0861988 |
| NDRG1 | N-myc downstream regulated 1 | 0.074706 |
| RPS2 | ribosomal protein S2 | 0.0447755 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0439172 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0399486 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.037897 |
| SMAD3 | SMAD family member 3 | 0.0372492 |
| EFNA5 | ephrin-A5 | 0.0366629 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0308057 |
| FAM107B | family with sequence similarity 107, member B | 0.0278922 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.02616 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0258607 |
| OGA | O-GlcNAcase | 0.0254349 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0252013 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0245098 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0235227 |
| SEPTIN9 | septin 9 | 0.0235062 |
| DSPP | dentin sialophosphoprotein | 0.0229689 |
| PLEC | plectin | 0.0223836 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0213427 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.021144 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0206358 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0203489 |
| ITGA6 | integrin, alpha 6 | 0.0203001 |
| HPCAL1 | hippocalcin-like 1 | 0.0200751 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0192542 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0190273 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0190226 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0188511 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0187225 |
| ATP13A3 | ATPase type 13A3 | 0.0183041 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0182235 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0180719 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0175316 |
| GDA | guanine deaminase | 0.0172999 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.017162 |
| MT2A | metallothionein 2A | 0.0171408 |
| RUNX1 | runt-related transcription factor 1 | 0.0169534 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0169081 |
| CDCP1 | CUB domain containing protein 1 | 0.0168887 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0167382 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0164423 |
| ARRDC3 | arrestin domain containing 3 | 0.0163447 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | 0.016164 |
| NCKAP1 | NCK-associated protein 1 | 0.016088 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0160859 |
| NEK7 | NIMA-related kinase 7 | 0.0160232 |
| MED13L | mediator complex subunit 13-like | 0.0159706 |
| ASPH | aspartate beta-hydroxylase | 0.0159622 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0159312 |
| RSL1D1 | ribosomal L1 domain containing 1 | 0.0157184 |
| ANO6 | anoctamin 6 | 0.0157114 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | 0.0155688 |
| FAM13A | family with sequence similarity 13, member A | 0.0154939 |
| MATR3 | matrin 3 | 0.0153123 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0153038 |
| RBM39 | RNA binding motif protein 39 | 0.0152032 |
| OSBPL3 | oxysterol binding protein-like 3 | 0.0150933 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0145226 |
| CUL3 | cullin 3 | 0.0144869 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0141104 |
| TOP1 | topoisomerase (DNA) I | 0.0139482 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0139293 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0136655 |
| MYOF | myoferlin | 0.0136401 |
| TPM3 | tropomyosin 3 | 0.0136248 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0136174 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0135378 |
| ABTB3 | ankyrin repeat and BTB domain containing 3 | 0.013534 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0134247 |
| IPO7 | importin 7 | 0.0133363 |
| RNF145 | ring finger protein 145 | 0.0132856 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0131478 |
| KIF5B | kinesin family member 5B | 0.0130447 |
| CAB39 | calcium binding protein 39 | 0.0130182 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0129397 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0128398 |
| PCSK5 | proprotein convertase subtilisin/kexin type 5 | 0.012767 |
| DSG2 | desmoglein 2 | 0.0126188 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0125983 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0125793 |
| FMNL2 | formin-like 2 | 0.0124814 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.012468 |
| AGPAT4 | 1-acylglycerol-3-phosphate O-acyltransferase 4 | 0.012392 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0123652 |
| SLTM | SAFB-like, transcription modulator | 0.0123508 |
| TMEM41B | transmembrane protein 41B | 0.0123463 |
| TMF1 | TATA element modulatory factor 1 | 0.0122992 |
| AP3S1 | adaptor-related protein complex 3, sigma 1 subunit | 0.0122521 |
| RCOR1 | REST corepressor 1 | 0.0121748 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | 0.012154 |
| IL1RAP | interleukin 1 receptor accessory protein | 0.0120887 |
| AFDN | afadin, adherens junction formation factor | 0.0119854 |
| HIBADH | 3-hydroxyisobutyrate dehydrogenase | 0.0118351 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0117865 |
| ZNF706 | zinc finger protein 706 | 0.0117471 |
| CNBP | CCHC-type zinc finger, nucleic acid binding protein | 0.0115869 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0114745 |
| CLTC | clathrin, heavy chain (Hc) | 0.0114341 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0113084 |
| Symbol | Name | Standardized Value |
|---|---|---|
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 | -0.159904 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.133853 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.133222 |
| TMSB10 | thymosin beta 10 | -0.122283 |
| LAMB3 | laminin, beta 3 | -0.106701 |
| KLK10 | kallikrein-related peptidase 10 | -0.101707 |
| ARPC1B | actin related protein 2/3 complex, subunit 1B, 41kDa | -0.101558 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0840157 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0819359 |
| SACK1A | scaffolding CK1 anchoring protein A | -0.0747345 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.071616 |
| MUC17 | mucin 17, cell surface associated | -0.069309 |
| TXNIP | thioredoxin interacting protein | -0.0621972 |
| LMO7 | LIM domain 7 | -0.0618072 |
| NPSR1 | neuropeptide S receptor 1 | -0.0581791 |
| MXD1 | MAX dimerization protein 1 | -0.0568721 |
| ARPC1A | actin related protein 2/3 complex, subunit 1A, 41kDa | -0.0529902 |
| TXNRD1 | thioredoxin reductase 1 | -0.0525311 |
| SLC35F3 | solute carrier family 35, member F3 | -0.052167 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0512916 |
| HMGA1 | high mobility group AT-hook 1 | -0.0494589 |
| TMBIM1 | transmembrane BAX inhibitor motif containing 1 | -0.0448847 |
| TPM4 | tropomyosin 4 | -0.04476 |
| VIM | vimentin | -0.0442989 |
| SMC3 | structural maintenance of chromosomes 3 | -0.0437001 |
| EGR1 | early growth response 1 | -0.0431526 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.042707 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0417736 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0412701 |
| PDXDC1 | pyridoxal-dependent decarboxylase domain containing 1 | -0.0401872 |
| DIAPH2 | diaphanous-related formin 2 | -0.0398006 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0387647 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0387147 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0383823 |
| VCAN | versican | -0.0380151 |
| SKAP2 | src kinase associated phosphoprotein 2 | -0.038013 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0378614 |
| LAMA4 | laminin, alpha 4 | -0.0375 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0374782 |
| PERP | PERP, TP53 apoptosis effector | -0.0358656 |
| ARF4 | ADP-ribosylation factor 4 | -0.0343821 |
| SP100 | SP100 nuclear antigen | -0.0342418 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0339715 |
| GREB1L | growth regulation by estrogen in breast cancer-like | -0.0318256 |
| HDAC9 | histone deacetylase 9 | -0.031773 |
| B2M | beta-2-microglobulin | -0.0312672 |
| S100A11 | S100 calcium binding protein A11 | -0.0312432 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0310424 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0309199 |
| FTL | ferritin, light polypeptide | -0.0302625 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.030181 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0299631 |
| RPL35A | ribosomal protein L35a | -0.0290033 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0288259 |
| PARD3 | par-3 family cell polarity regulator | -0.0279839 |
| RASAL2 | RAS protein activator like 2 | -0.0278393 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0274188 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0273905 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0273776 |
| FERMT1 | fermitin family member 1 | -0.0273451 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0266475 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0264315 |
| EGFR | epidermal growth factor receptor | -0.0255395 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0254119 |
| GNAS | GNAS complex locus | -0.025315 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0252559 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | -0.02449 |
| PRSS3 | protease, serine, 3 | -0.0241006 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0240375 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0236955 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.023632 |
| AK1 | adenylate kinase 1 | -0.0236258 |
| FLNB | filamin B, beta | -0.0234845 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0230687 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0226134 |
| ACTN4 | actinin, alpha 4 | -0.0225807 |
| PARD6B | par-6 family cell polarity regulator beta | -0.0222169 |
| POTEF | POTE ankyrin domain family, member F | -0.0222014 |
| DIAPH1 | diaphanous-related formin 1 | -0.0216565 |
| RIOK3 | RIO kinase 3 | -0.0215361 |
| ATG16L1 | autophagy related 16-like 1 (S. cerevisiae) | -0.0208441 |
| UBE2R2 | ubiquitin-conjugating enzyme E2R 2 | -0.0200899 |
| MIDN | midnolin | -0.0198402 |
| RAPH1 | Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 | -0.0196773 |
| ANXA2 | annexin A2 | -0.0196648 |
| INPP5D | inositol polyphosphate-5-phosphatase, 145kDa | -0.0195752 |
| PGK1 | phosphoglycerate kinase 1 | -0.0195433 |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 | -0.0194219 |
| DENND2C | DENN/MADD domain containing 2C | -0.0193324 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.018454 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa | -0.0183599 |
| XIAP | X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase | -0.0183132 |
| LAMC2 | laminin, gamma 2 | -0.0182779 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0179714 |
| NBEAL1 | neurobeachin-like 1 | -0.0179686 |
| JUP | junction plakoglobin | -0.0178647 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0178615 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.017806 |
| TGFA | transforming growth factor, alpha | -0.0177743 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0177054 |
