| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | L-Thyroxine (sodium salt pentahydrate) perturbation in BT-474 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the L-Thyroxine (sodium salt pentahydrate)_BT-474 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ASPH | aspartate beta-hydroxylase | 0.0983163 |
| CLTC | clathrin, heavy chain (Hc) | 0.0955324 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0896629 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0792145 |
| DSPP | dentin sialophosphoprotein | 0.0718981 |
| ENO1 | enolase 1, (alpha) | 0.0627782 |
| SET | SET nuclear proto-oncogene | 0.0601853 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0549271 |
| VEGFA | vascular endothelial growth factor A | 0.0472828 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0455874 |
| FAM13A | family with sequence similarity 13, member A | 0.042772 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.041838 |
| DTNA | dystrobrevin, alpha | 0.0414428 |
| RPS2 | ribosomal protein S2 | 0.0412751 |
| NDRG1 | N-myc downstream regulated 1 | 0.0411347 |
| VMP1 | vacuole membrane protein 1 | 0.0408496 |
| TMEM123 | transmembrane protein 123 | 0.0406458 |
| CREB5 | cAMP responsive element binding protein 5 | 0.0383749 |
| DSTN | destrin (actin depolymerizing factor) | 0.0373176 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.035406 |
| LDHA | lactate dehydrogenase A | 0.035013 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0346323 |
| MLLT6 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6 | 0.0344284 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0339018 |
| TOM1L1 | target of myb1 (chicken)-like 1 | 0.033286 |
| SPAG9 | sperm associated antigen 9 | 0.0330438 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0323127 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.031841 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0317467 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.0316744 |
| ANLN | anillin, actin binding protein | 0.0308085 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0306269 |
| EGFR | epidermal growth factor receptor | 0.0306258 |
| SETD5 | SET domain containing 5 | 0.0305486 |
| CANX | calnexin | 0.0302928 |
| FLNB | filamin B, beta | 0.030044 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0298384 |
| NCKAP1 | NCK-associated protein 1 | 0.0296916 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0296048 |
| MYOF | myoferlin | 0.0294322 |
| RPL3 | ribosomal protein L3 | 0.0291586 |
| MYO9A | myosin IXA | 0.0288829 |
| AURKA | aurora kinase A | 0.0282329 |
| PGK1 | phosphoglycerate kinase 1 | 0.0280126 |
| SLFN5 | schlafen family member 5 | 0.0275262 |
| ECT2 | epithelial cell transforming 2 | 0.0274514 |
| FAM219A | family with sequence similarity 219, member A | 0.0274031 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0272429 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0272301 |
| NMD3 | NMD3 ribosome export adaptor | 0.0272191 |
| ANO6 | anoctamin 6 | 0.0271486 |
| RPL19 | ribosomal protein L19 | 0.0271239 |
| CENPF | centromere protein F, 350/400kDa | 0.0267768 |
| DSG2 | desmoglein 2 | 0.0266405 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0265405 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0264741 |
| DHX40 | DEAH (Asp-Glu-Ala-His) box polypeptide 40 | 0.0264169 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0262126 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0258761 |
| APP | amyloid beta (A4) precursor protein | 0.0252373 |
| TAOK1 | TAO kinase 1 | 0.0252191 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0249759 |
| ATXN2 | ataxin 2 | 0.0248596 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0248103 |
| JMJD1C | jumonji domain containing 1C | 0.0243405 |
| NCOA3 | nuclear receptor coactivator 3 | 0.0243336 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0242545 |
| POTEF | POTE ankyrin domain family, member F | 0.0242173 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0239877 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | 0.0239693 |
| PKM | pyruvate kinase, muscle | 0.023956 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.0236023 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | 0.0233291 |
| KRT19 | keratin 19, type I | 0.0232132 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0228583 |
| ATAD2 | ATPase family, AAA domain containing 2 | 0.0224362 |
| PFDN4 | prefoldin subunit 4 | 0.0223549 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0223414 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.022318 |
| TAC4 | tachykinin 4 (hemokinin) | 0.0222146 |
| PNN | pinin, desmosome associated protein | 0.0221364 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.021997 |
| BZW2 | basic leucine zipper and W2 domains 2 | 0.0217681 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0217383 |
| ESRP1 | epithelial splicing regulatory protein 1 | 0.0217018 |
| ITGB6 | integrin, beta 6 | 0.0215429 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0214999 |
| AHR | aryl hydrocarbon receptor | 0.021382 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.0213151 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0211108 |
| DST | dystonin | 0.0210209 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0209139 |
| SLC22A23 | solute carrier family 22, member 23 | 0.0209032 |
| RREB1 | ras responsive element binding protein 1 | 0.0208722 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.02086 |
| PDS5B | PDS5 cohesin associated factor B | 0.0207509 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0204135 |
| YEATS2 | YEATS domain containing 2 | 0.0203927 |
| NBEAL1 | neurobeachin-like 1 | 0.0203548 |
| PPP1R9B | protein phosphatase 1, regulatory subunit 9B | 0.0201565 |
| Symbol | Name | Standardized Value |
|---|---|---|
| RPL23 | ribosomal protein L23 | -0.130164 |
| ERBB2 | erb-b2 receptor tyrosine kinase 2 | -0.0997006 |
| LASP1 | LIM and SH3 protein 1 | -0.0713483 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0673293 |
| RPL35A | ribosomal protein L35a | -0.0567682 |
| PBX1 | pre-B-cell leukemia homeobox 1 | -0.0550294 |
| TMSB10 | thymosin beta 10 | -0.050592 |
| CATSPERB | catsper channel auxiliary subunit beta | -0.0500114 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0481183 |
| PSMD3 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 | -0.0478404 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0470611 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0459696 |
| SMYD3 | SET and MYND domain containing 3 | -0.042705 |
| PTK2 | protein tyrosine kinase 2 | -0.0425516 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0402706 |
| GNAS | GNAS complex locus | -0.0377144 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0372934 |
| CDK12 | cyclin-dependent kinase 12 | -0.0343377 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0340573 |
| LGALS12 | lectin, galactoside-binding, soluble, 12 | -0.0336531 |
| S100A8 | S100 calcium binding protein A8 | -0.0327634 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0326788 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0326649 |
| S100A9 | S100 calcium binding protein A9 | -0.0314111 |
| KAZN | kazrin, periplakin interacting protein | -0.0311887 |
| BCAS1 | breast carcinoma amplified sequence 1 | -0.030889 |
| GOLGB1 | golgin B1 | -0.0307261 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.0304936 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.029617 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0296053 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0292914 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0291808 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.0283648 |
| DYNLRB1 | dynein, light chain, roadblock-type 1 | -0.0283117 |
| DNAH14 | dynein, axonemal, heavy chain 14 | -0.0279773 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0276273 |
| YBX3 | Y box binding protein 3 | -0.0276246 |
| GRB7 | growth factor receptor-bound protein 7 | -0.0275511 |
| MAPK8 | mitogen-activated protein kinase 8 | -0.027235 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0269198 |
| EHMT1 | euchromatic histone-lysine N-methyltransferase 1 | -0.0269066 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0267275 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0267142 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0263076 |
| IL1RAPL2 | interleukin 1 receptor accessory protein-like 2 | -0.0262439 |
| SP100 | SP100 nuclear antigen | -0.0259461 |
| MSI2 | musashi RNA-binding protein 2 | -0.0254941 |
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 | -0.0254297 |
| INTS6 | integrator complex subunit 6 | -0.0252177 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0250401 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | -0.0250036 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | -0.0243535 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.02402 |
| RBM47 | RNA binding motif protein 47 | -0.023612 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0235441 |
| POU2F1 | POU class 2 homeobox 1 | -0.0235019 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0234631 |
| CD46 | CD46 molecule, complement regulatory protein | -0.0232667 |
| TENM2 | teneurin transmembrane protein 2 | -0.0230767 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0230353 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0226389 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0224086 |
| PRRC2C | proline-rich coiled-coil 2C | -0.022343 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0220189 |
| ZFHX3 | zinc finger homeobox 3 | -0.0219067 |
| TFRC | transferrin receptor | -0.0218836 |
| SFPQ | splicing factor proline/glutamine-rich | -0.0218245 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | -0.0217553 |
| MYO1D | myosin ID | -0.0216384 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 | -0.0216087 |
| INSR | insulin receptor | -0.021474 |
| RNF216 | ring finger protein 216 | -0.0213854 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | -0.0213817 |
| PAWR | PRKC, apoptosis, WT1, regulator | -0.0212137 |
| RASA2 | RAS p21 protein activator 2 | -0.0209912 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0209592 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | -0.0208079 |
| RBM25 | RNA binding motif protein 25 | -0.0207639 |
| RBM5 | RNA binding motif protein 5 | -0.0207511 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | -0.0207209 |
| RPLP1 | ribosomal protein, large, P1 | -0.0206757 |
| KIF16B | kinesin family member 16B | -0.0204599 |
| ABHD17C | abhydrolase domain containing 17C | -0.0203945 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0203603 |
| RPL37 | ribosomal protein L37 | -0.0203552 |
| RPS24 | ribosomal protein S24 | -0.0201934 |
| HMGB1 | high mobility group box 1 | -0.0201569 |
| DENND1B | DENN/MADD domain containing 1B | -0.0200783 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0199469 |
| TP53INP2 | tumor protein p53 inducible nuclear protein 2 | -0.0199414 |
| PPM1D | protein phosphatase, Mg2+/Mn2+ dependent, 1D | -0.0195004 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0194561 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | -0.0193445 |
| RPL34 | ribosomal protein L34 | -0.0192999 |
| PHF20L1 | PHD finger protein 20-like 1 | -0.0192036 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.0191922 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0191661 |
| TC2N | tandem C2 domains, nuclear | -0.0191642 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0190859 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0190641 |
