| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | L-Thyroxine (sodium salt pentahydrate) perturbation in C32 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the L-Thyroxine (sodium salt pentahydrate)_C32 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.116978 |
| CD109 | CD109 molecule | 0.114172 |
| NLGN1 | neuroligin 1 | 0.0800984 |
| FMNL2 | formin-like 2 | 0.0727178 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0683359 |
| FN1 | fibronectin 1 | 0.0674578 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0635009 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.060443 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.0587544 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0565784 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0547417 |
| NDRG1 | N-myc downstream regulated 1 | 0.0538246 |
| GPC6 | glypican 6 | 0.0530936 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0517937 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0486416 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0449353 |
| CALU | calumenin | 0.0443114 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0434857 |
| CTTNBP2 | cortactin binding protein 2 | 0.0423199 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0413864 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0397176 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0368694 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0355459 |
| PHF21A | PHD finger protein 21A | 0.0353845 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0352701 |
| CANX | calnexin | 0.0351203 |
| ENO1 | enolase 1, (alpha) | 0.0345199 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0342575 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0341761 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0338494 |
| FYN | FYN proto-oncogene, Src family tyrosine kinase | 0.033515 |
| TAC4 | tachykinin 4 (hemokinin) | 0.0326809 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.0325788 |
| GOLGA4 | golgin A4 | 0.0324604 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.03158 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0303983 |
| CADM1 | cell adhesion molecule 1 | 0.0299752 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0296476 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0290294 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0288261 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0288047 |
| NBAS | neuroblastoma amplified sequence | 0.0284478 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | 0.0283918 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0281124 |
| ZNF292 | zinc finger protein 292 | 0.0279716 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0271748 |
| CENPF | centromere protein F, 350/400kDa | 0.0269369 |
| NT5C3A | 5'-nucleotidase, cytosolic IIIA | 0.0268159 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0267921 |
| RPS2 | ribosomal protein S2 | 0.026771 |
| CALR | calreticulin | 0.0262075 |
| SCFD2 | sec1 family domain containing 2 | 0.0261076 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0258297 |
| RUNX1 | runt-related transcription factor 1 | 0.0256875 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0249207 |
| TNIK | TRAF2 and NCK interacting kinase | 0.024895 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0248626 |
| DST | dystonin | 0.024437 |
| MACROD2 | MACRO domain containing 2 | 0.0238389 |
| STXBP1 | syntaxin binding protein 1 | 0.0237561 |
| BPNT2 | 3'(2'), 5'-bisphosphate nucleotidase 2 | 0.0237543 |
| FRMD4A | FERM domain containing 4A | 0.0230622 |
| CUX1 | cut-like homeobox 1 | 0.0230357 |
| AHR | aryl hydrocarbon receptor | 0.0226441 |
| KDM5B | lysine (K)-specific demethylase 5B | 0.0222474 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0221966 |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 | 0.0220789 |
| SSBP3 | single stranded DNA binding protein 3 | 0.0219642 |
| MEF2A | myocyte enhancer factor 2A | 0.0216631 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0216606 |
| FRMD6 | FERM domain containing 6 | 0.0215542 |
| COPA | coatomer protein complex, subunit alpha | 0.0214641 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0209752 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0207021 |
| RNF24 | ring finger protein 24 | 0.020624 |
| HELZ | helicase with zinc finger | 0.0201354 |
| PIAS2 | protein inhibitor of activated STAT, 2 | 0.0201263 |
| TRIM2 | tripartite motif containing 2 | 0.0200023 |
| PRKD1 | protein kinase D1 | 0.0198857 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.0198446 |
| IVNS1ABP | influenza virus NS1A binding protein | 0.0198267 |
| TNFRSF19 | tumor necrosis factor receptor superfamily, member 19 | 0.0196838 |
| PRELID2 | PRELI domain containing 2 | 0.0195532 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0194046 |
| PLA2G4A | phospholipase A2, group IVA (cytosolic, calcium-dependent) | 0.0192983 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0192745 |
| RO60 | Ro60, Y RNA binding protein | 0.0192742 |
| NAV3 | neuron navigator 3 | 0.0189806 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | 0.0188389 |
| TPR | translocated promoter region, nuclear basket protein | 0.0187308 |
| CCDC91 | coiled-coil domain containing 91 | 0.0187193 |
| MTDH | metadherin | 0.018562 |
| MYO10 | myosin X | 0.0185384 |
| ANK2 | ankyrin 2, neuronal | 0.018397 |
| ADM | adrenomedullin | 0.0183073 |
| NKTR | natural killer cell triggering receptor | 0.0182415 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0182107 |
| RYBP | RING1 and YY1 binding protein | 0.0181704 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.018161 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0181083 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.164643 |
| MT2A | metallothionein 2A | -0.129754 |
| VIM | vimentin | -0.0871062 |
| RPLP1 | ribosomal protein, large, P1 | -0.0561718 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0491287 |
| TMSB10 | thymosin beta 10 | -0.0414999 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0408133 |
| VGF | VGF nerve growth factor inducible | -0.0400704 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0340039 |
| MT1X | metallothionein 1X | -0.0331022 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0284992 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0268496 |
| OSMR | oncostatin M receptor | -0.0260294 |
| EGR1 | early growth response 1 | -0.0253088 |
| IER3 | immediate early response 3 | -0.0251702 |
| RPL35A | ribosomal protein L35a | -0.0247541 |
| IFRD1 | interferon-related developmental regulator 1 | -0.0234643 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0231659 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0224962 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0221327 |
| RPS19 | ribosomal protein S19 | -0.0204263 |
| ACTG1 | actin gamma 1 | -0.0199143 |
| TNNC1 | troponin C type 1 (slow) | -0.0198307 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0196424 |
| CD74 | CD74 molecule, major histocompatibility complex, class II invariant chain | -0.0195131 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0183904 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0173607 |
| AHNAK | AHNAK nucleoprotein | -0.0171465 |
| EXOC6B | exocyst complex component 6B | -0.016805 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | -0.016541 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | -0.0159509 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0159379 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0155242 |
| LMNA | lamin A/C | -0.0151932 |
| RPL19 | ribosomal protein L19 | -0.0151083 |
| RPS21 | ribosomal protein S21 | -0.0146418 |
| RPS8 | ribosomal protein S8 | -0.0145886 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0145467 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | -0.014488 |
| RPL32 | ribosomal protein L32 | -0.0144229 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0143479 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0142421 |
| RPS5 | ribosomal protein S5 | -0.0141164 |
| RPL34 | ribosomal protein L34 | -0.0140832 |
| FRMD5 | FERM domain containing 5 | -0.0140687 |
| ITGB3BP | integrin beta 3 binding protein (beta3-endonexin) | -0.0138696 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0136818 |
| RCAN1 | regulator of calcineurin 1 | -0.0136603 |
| MED13L | mediator complex subunit 13-like | -0.0135541 |
| RPLP0 | ribosomal protein, large, P0 | -0.0134784 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.013246 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0132458 |
| RPS20 | ribosomal protein S20 | -0.0131967 |
| S100A10 | S100 calcium binding protein A10 | -0.0131898 |
| S100A9 | S100 calcium binding protein A9 | -0.0130436 |
| RPS24 | ribosomal protein S24 | -0.0127214 |
| RPL31 | ribosomal protein L31 | -0.0127004 |
| RPS11 | ribosomal protein S11 | -0.0126151 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0123765 |
| RPL28 | ribosomal protein L28 | -0.0121843 |
| RPL23 | ribosomal protein L23 | -0.0120557 |
| RPL26 | ribosomal protein L26 | -0.011996 |
| RPL8 | ribosomal protein L8 | -0.011848 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0117087 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0117048 |
| LEF1 | lymphoid enhancer-binding factor 1 | -0.0116895 |
| TCF20 | transcription factor 20 (AR1) | -0.0116561 |
| HDAC8 | histone deacetylase 8 | -0.0116495 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0115395 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0113881 |
| SEM1 | SEM1 26S proteasome subunit | -0.0107977 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | -0.0107369 |
| BSG | basigin (Ok blood group) | -0.0107302 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.0107284 |
| SGO2 | shugoshin 2 | -0.0106222 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | -0.0105129 |
| MIDN | midnolin | -0.0105115 |
| ETV1 | ets variant 1 | -0.0103945 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0102995 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0101144 |
| EVI5 | ecotropic viral integration site 5 | -0.0101044 |
| MRTFA | myocardin related transcription factor A | -0.0100564 |
| ZFAND5 | zinc finger, AN1-type domain 5 | -0.00986789 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.00983866 |
| CD59 | CD59 molecule, complement regulatory protein | -0.00983201 |
| ATP5F1E | ATP synthase F1 subunit epsilon | -0.00974901 |
| TBCD | tubulin folding cofactor D | -0.00972817 |
| COL1A2 | collagen, type I, alpha 2 | -0.00970906 |
| MED27 | mediator complex subunit 27 | -0.00970767 |
| GNB2 | guanine nucleotide binding protein (G protein), beta polypeptide 2 | -0.00970721 |
| DPYD | dihydropyrimidine dehydrogenase | -0.00967975 |
| RPS29 | ribosomal protein S29 | -0.00966032 |
| NSD2 | nuclear receptor binding SET domain protein 2 | -0.00960391 |
| RPS15 | ribosomal protein S15 | -0.00952397 |
| RPL30 | ribosomal protein L30 | -0.00952339 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0095197 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | -0.0094543 |
| SPIDR | scaffolding protein involved in DNA repair | -0.00935934 |
| SKAP2 | src kinase associated phosphoprotein 2 | -0.00935557 |
| RPL27A | ribosomal protein L27a | -0.00934897 |
