| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | L-Thyroxine (sodium salt pentahydrate) perturbation in CFPAC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the L-Thyroxine (sodium salt pentahydrate)_CFPAC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SAMD4A | sterile alpha motif domain containing 4A | 0.120047 |
| FNDC3B | fibronectin type III domain containing 3B | 0.116576 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0819493 |
| DTNA | dystrobrevin, alpha | 0.0720431 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0622659 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0592693 |
| FAM3C | family with sequence similarity 3, member C | 0.0560182 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0513419 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0502468 |
| TGM2 | transglutaminase 2 | 0.0497369 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0450296 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.044342 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0440039 |
| NABP1 | nucleic acid binding protein 1 | 0.0434454 |
| BCL2L1 | BCL2-like 1 | 0.0422477 |
| ASPH | aspartate beta-hydroxylase | 0.0419634 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0413092 |
| RAD51B | RAD51 paralog B | 0.0411912 |
| VEGFA | vascular endothelial growth factor A | 0.0409341 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0394972 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0394006 |
| RPS2 | ribosomal protein S2 | 0.0383491 |
| LAMC2 | laminin, gamma 2 | 0.0376037 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0375082 |
| MCL1 | myeloid cell leukemia 1 | 0.0361118 |
| SEPTIN9 | septin 9 | 0.0356281 |
| EFNA5 | ephrin-A5 | 0.0355147 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.035371 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0345805 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 0.0343308 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0340153 |
| SMAD3 | SMAD family member 3 | 0.0331369 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.032358 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0310991 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0308847 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0307517 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0302748 |
| ACTN1 | actinin, alpha 1 | 0.0293004 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0292232 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0290659 |
| BARX2 | BARX homeobox 2 | 0.0290322 |
| SVIL | supervillin | 0.0281117 |
| DST | dystonin | 0.0278347 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0271614 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.027022 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0267799 |
| FAM107B | family with sequence similarity 107, member B | 0.0262402 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0261175 |
| INTS6 | integrator complex subunit 6 | 0.0254864 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0251409 |
| HPCAL1 | hippocalcin-like 1 | 0.0243068 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0234142 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0233742 |
| MSN | moesin | 0.0231671 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0228704 |
| VMP1 | vacuole membrane protein 1 | 0.0226126 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0224476 |
| KIAA1217 | KIAA1217 | 0.0222225 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0220314 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0219983 |
| GPATCH8 | G patch domain containing 8 | 0.0216798 |
| CMIP | c-Maf inducing protein | 0.0213858 |
| HDAC9 | histone deacetylase 9 | 0.0212566 |
| NOTCH2 | notch 2 | 0.0211778 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0206946 |
| PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 | 0.0206668 |
| RUNX1 | runt-related transcription factor 1 | 0.0206321 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0205908 |
| JAK1 | Janus kinase 1 | 0.0196189 |
| NTN4 | netrin 4 | 0.0196028 |
| POTEF | POTE ankyrin domain family, member F | 0.0195998 |
| SACK1B | scaffolding CK1 anchoring protein B | 0.019549 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0194974 |
| ARRDC3 | arrestin domain containing 3 | 0.0194925 |
| OPTN | optineurin | 0.019224 |
| CD44 | CD44 molecule (Indian blood group) | 0.0191442 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0191219 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0188399 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.0187094 |
| PTPRE | protein tyrosine phosphatase, receptor type, E | 0.0186683 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0182736 |
| FRMD6 | FERM domain containing 6 | 0.0181029 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0181017 |
| RCOR1 | REST corepressor 1 | 0.0180687 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0180677 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0180648 |
| FERMT2 | fermitin family member 2 | 0.0180373 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | 0.0179705 |
| RPS6 | ribosomal protein S6 | 0.0179645 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0178519 |
| CDCP1 | CUB domain containing protein 1 | 0.0176849 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0176784 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0175269 |
| IL6ST | interleukin 6 signal transducer | 0.0172979 |
| TMCC3 | transmembrane and coiled-coil domain family 3 | 0.0172076 |
| GPATCH2L | G patch domain containing 2-like | 0.0171882 |
| SMYD3 | SET and MYND domain containing 3 | 0.0171185 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 | 0.0170375 |
| TJP1 | tight junction protein 1 | 0.0169922 |
| NAV2 | neuron navigator 2 | 0.016881 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.235978 |
| MMP7 | matrix metallopeptidase 7 | -0.167952 |
| TMSB10 | thymosin beta 10 | -0.16011 |
| CP | ceruloplasmin (ferroxidase) | -0.133555 |
| LAMB3 | laminin, beta 3 | -0.111386 |
| HLA-B | major histocompatibility complex, class I, B | -0.105158 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.1042 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.103704 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.100963 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0976573 |
| PGK1 | phosphoglycerate kinase 1 | -0.094283 |
| VIM | vimentin | -0.0911442 |
| S100A6 | S100 calcium binding protein A6 | -0.0897601 |
| PTMA | prothymosin, alpha | -0.0821592 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0793863 |
| TMSB4X | thymosin beta 4, X-linked | -0.079325 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0781544 |
| LMO7 | LIM domain 7 | -0.0755928 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0741893 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0723714 |
| EZR | ezrin | -0.0696672 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0652384 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0629015 |
| NDRG1 | N-myc downstream regulated 1 | -0.0624993 |
| B2M | beta-2-microglobulin | -0.0590968 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0585531 |
| HLA-A | major histocompatibility complex, class I, A | -0.0579912 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0550901 |
| ACTG1 | actin gamma 1 | -0.0542152 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0509019 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0489462 |
| IER3 | immediate early response 3 | -0.0488774 |
| RPL35A | ribosomal protein L35a | -0.0488307 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0481144 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | -0.0467235 |
| ENO1 | enolase 1, (alpha) | -0.0466567 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0463448 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0460369 |
| HLA-E | major histocompatibility complex, class I, E | -0.0456925 |
| KLF6 | Kruppel-like factor 6 | -0.045656 |
| AHNAK | AHNAK nucleoprotein | -0.0453432 |
| MT1X | metallothionein 1X | -0.044773 |
| RRBP1 | ribosome binding protein 1 | -0.0443502 |
| INSIG1 | insulin induced gene 1 | -0.0433572 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0433302 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0420896 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0418763 |
| GNAS | GNAS complex locus | -0.0418025 |
| ANXA2 | annexin A2 | -0.0410569 |
| LMNA | lamin A/C | -0.0407195 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0407153 |
| S100A10 | S100 calcium binding protein A10 | -0.0392318 |
| TPM4 | tropomyosin 4 | -0.0390144 |
| FDPS | farnesyl diphosphate synthase | -0.0379996 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0378188 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.037559 |
| PLAT | plasminogen activator, tissue | -0.0370249 |
| FAM162A | family with sequence similarity 162, member A | -0.0368981 |
| FLNB | filamin B, beta | -0.0367428 |
| LDHA | lactate dehydrogenase A | -0.036551 |
| CSTB | cystatin B (stefin B) | -0.0362169 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0358787 |
| LASP1 | LIM and SH3 protein 1 | -0.0356759 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.0352959 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0351328 |
| ACTN4 | actinin, alpha 4 | -0.0348621 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0346742 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0334908 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0333134 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0330949 |
| MSMO1 | methylsterol monooxygenase 1 | -0.0326043 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0323988 |
| KRT19 | keratin 19, type I | -0.0323302 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0313788 |
| MUC4 | mucin 4, cell surface associated | -0.0313706 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0311442 |
| S100A11 | S100 calcium binding protein A11 | -0.0310265 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0308068 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0304194 |
| TMEM123 | transmembrane protein 123 | -0.0301696 |
| FOXO3 | forkhead box O3 | -0.0297188 |
| AHNAK2 | AHNAK nucleoprotein 2 | -0.0294783 |
| JUP | junction plakoglobin | -0.0293598 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0292571 |
| ARF1 | ADP-ribosylation factor 1 | -0.0288603 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0288044 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0285558 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0281262 |
| SPAG9 | sperm associated antigen 9 | -0.0278362 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0275059 |
| CD2AP | CD2-associated protein | -0.0272261 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.027098 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0270643 |
| WDR45B | WD repeat domain 45B | -0.0269471 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0267053 |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 | -0.0266267 |
| CLINT1 | clathrin interactor 1 | -0.0265164 |
| RLF | rearranged L-myc fusion | -0.0260863 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0259331 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0258752 |
