| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | L-Thyroxine (sodium salt pentahydrate) perturbation in HCT15 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the L-Thyroxine (sodium salt pentahydrate)_HCT15 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NDRG1 | N-myc downstream regulated 1 | 0.187379 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.147264 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.113947 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0725457 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0698046 |
| GOLGA4 | golgin A4 | 0.0642807 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0613823 |
| VEGFA | vascular endothelial growth factor A | 0.0593221 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0533603 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0516937 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0513806 |
| HELZ | helicase with zinc finger | 0.0497749 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0479663 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0479349 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0419757 |
| B2M | beta-2-microglobulin | 0.0408118 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0394519 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0362039 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.0335869 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0330485 |
| WDR45B | WD repeat domain 45B | 0.0310415 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0308028 |
| RNMT | RNA (guanine-7-) methyltransferase | 0.0299804 |
| TMF1 | TATA element modulatory factor 1 | 0.0295592 |
| ENO1 | enolase 1, (alpha) | 0.0294337 |
| RPL3 | ribosomal protein L3 | 0.0291069 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0289095 |
| RNF24 | ring finger protein 24 | 0.0286274 |
| SRP54 | signal recognition particle 54kDa | 0.0261049 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0251972 |
| MXI1 | MAX interactor 1, dimerization protein | 0.024556 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0243821 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0243634 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0234746 |
| SEC24A | SEC24 family member A | 0.0232279 |
| FAM117B | family with sequence similarity 117, member B | 0.0229922 |
| FAM162A | family with sequence similarity 162, member A | 0.0226119 |
| ANKRD37 | ankyrin repeat domain 37 | 0.0225237 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0221228 |
| LMAN1 | lectin, mannose-binding, 1 | 0.0219603 |
| PGM3 | phosphoglucomutase 3 | 0.0217692 |
| ARFGEF3 | ARFGEF family member 3 | 0.0217293 |
| FNIP1 | folliculin interacting protein 1 | 0.0212144 |
| SETD5 | SET domain containing 5 | 0.0210682 |
| ARRDC3 | arrestin domain containing 3 | 0.0203975 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | 0.0196971 |
| MATR3 | matrin 3 | 0.0196737 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.0195628 |
| INSIG2 | insulin induced gene 2 | 0.0185806 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.018494 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0182516 |
| NUP58 | nucleoporin 58 | 0.0182412 |
| BRD2 | bromodomain containing 2 | 0.0178118 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0175688 |
| SUPT6H | suppressor of Ty 6 homolog (S. cerevisiae) | 0.0175622 |
| PDGFA | platelet-derived growth factor alpha polypeptide | 0.0173512 |
| SNX3 | sorting nexin 3 | 0.0170447 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0168572 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.0167966 |
| WASF2 | WAS protein family, member 2 | 0.0167721 |
| RPS18 | ribosomal protein S18 | 0.0163844 |
| TMEM65 | transmembrane protein 65 | 0.0163497 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0161432 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0159769 |
| COG6 | component of oligomeric golgi complex 6 | 0.0156038 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0155375 |
| RAB18 | RAB18, member RAS oncogene family | 0.0154456 |
| PDXDC1 | pyridoxal-dependent decarboxylase domain containing 1 | 0.0154414 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0153488 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0148966 |
| SFXN1 | sideroflexin 1 | 0.0148919 |
| UBC | ubiquitin C | 0.0148353 |
| CDK18 | cyclin-dependent kinase 18 | 0.0147017 |
| RIOK3 | RIO kinase 3 | 0.0146925 |
| ZNF160 | zinc finger protein 160 | 0.014622 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0146045 |
| GPC5 | glypican 5 | 0.0144798 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0143982 |
| RUNX1 | runt-related transcription factor 1 | 0.0143292 |
| ADM | adrenomedullin | 0.0141709 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0140374 |
| BPNT2 | 3'(2'), 5'-bisphosphate nucleotidase 2 | 0.0140346 |
| DIAPH1 | diaphanous-related formin 1 | 0.0137587 |
| AP3S1 | adaptor-related protein complex 3, sigma 1 subunit | 0.013656 |
| RPS2 | ribosomal protein S2 | 0.0135885 |
| RPL21 | ribosomal protein L21 | 0.0134672 |
| HERC3 | HECT and RLD domain containing E3 ubiquitin protein ligase 3 | 0.013291 |
| TPM3 | tropomyosin 3 | 0.0132658 |
| MIMS1 | mitochondrial inner membrane scaffold 1 | 0.0131409 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0131387 |
| HM13 | histocompatibility (minor) 13 | 0.0130732 |
| SEPTIN7 | septin 7 | 0.0130042 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0129931 |
| ATF4 | activating transcription factor 4 | 0.0127354 |
| GALNT3 | polypeptide N-acetylgalactosaminyltransferase 3 | 0.012455 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0124417 |
| TM9SF2 | transmembrane 9 superfamily member 2 | 0.0123555 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 0.01232 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme | 0.0122182 |
| HMGA1 | high mobility group AT-hook 1 | 0.0121397 |
| Symbol | Name | Standardized Value |
|---|---|---|
| AHNAK | AHNAK nucleoprotein | -0.224026 |
| FAT1 | FAT atypical cadherin 1 | -0.195573 |
| TXNRD1 | thioredoxin reductase 1 | -0.0925944 |
| RAD51B | RAD51 paralog B | -0.0904098 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.088877 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0823484 |
| TMSB10 | thymosin beta 10 | -0.0790926 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0770424 |
| TENM3 | teneurin transmembrane protein 3 | -0.075317 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0748398 |
| SMYD3 | SET and MYND domain containing 3 | -0.0699961 |
| MKI67 | marker of proliferation Ki-67 | -0.0682728 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0651665 |
| PRELID2 | PRELI domain containing 2 | -0.0648875 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0616471 |
| MED13L | mediator complex subunit 13-like | -0.0604831 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0597959 |
| VCL | vinculin | -0.0592706 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0554152 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0544337 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | -0.0542216 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0530134 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0529127 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0526017 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0520744 |
| JMJD1C | jumonji domain containing 1C | -0.0499092 |
| SLC38A2 | solute carrier family 38, member 2 | -0.04961 |
| GPHN | gephyrin | -0.049105 |
| EZR | ezrin | -0.0473684 |
| FHIT | fragile histidine triad | -0.0470994 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0470261 |
| SPIDR | scaffolding protein involved in DNA repair | -0.0469922 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0454104 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0448739 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | -0.0446096 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0441002 |
| PTMA | prothymosin, alpha | -0.0439546 |
| TCF12 | transcription factor 12 | -0.0434653 |
| SERINC5 | serine incorporator 5 | -0.0434174 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0430853 |
| FRMD5 | FERM domain containing 5 | -0.0429846 |
| NF1 | neurofibromin 1 | -0.0425134 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.042487 |
| ZC3H12B | zinc finger CCCH-type containing 12B | -0.0419258 |
| CENPF | centromere protein F, 350/400kDa | -0.04156 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0405739 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0405485 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0401534 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0401325 |
| ACTG1 | actin gamma 1 | -0.0375947 |
| BPTF | bromodomain PHD finger transcription factor | -0.0370045 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0365159 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.036408 |
| MYO9A | myosin IXA | -0.0363626 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0361344 |
| RPL35A | ribosomal protein L35a | -0.0358782 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0357301 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0355235 |
| KDM4C | lysine (K)-specific demethylase 4C | -0.0352585 |
| PRRC2B | proline-rich coiled-coil 2B | -0.0348237 |
| RPS24 | ribosomal protein S24 | -0.034651 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0346394 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0345222 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0341623 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | -0.0338744 |
| ERBIN | erbb2 interacting protein | -0.0334934 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0328448 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0328229 |
| LARP4B | La ribonucleoprotein domain family, member 4B | -0.0328064 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0325076 |
| SON | SON DNA binding protein | -0.0323638 |
| ACBD6 | acyl-CoA binding domain containing 6 | -0.0322215 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.0318352 |
| EHBP1 | EH domain binding protein 1 | -0.0318246 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | -0.0315672 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0314389 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0312087 |
| KLF12 | Kruppel-like factor 12 | -0.0311786 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0310314 |
| PTK2 | protein tyrosine kinase 2 | -0.0307588 |
| CDK12 | cyclin-dependent kinase 12 | -0.0305677 |
| APP | amyloid beta (A4) precursor protein | -0.0305105 |
| CARD16 | caspase recruitment domain family, member 16 | -0.0304438 |
| SUMF1 | sulfatase modifying factor 1 | -0.0303685 |
| NFIA | nuclear factor I/A | -0.030201 |
| HMGB2 | high mobility group box 2 | -0.0301869 |
| ACTN4 | actinin, alpha 4 | -0.0298061 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.029751 |
| SATB2 | SATB homeobox 2 | -0.0296941 |
| PARD3 | par-3 family cell polarity regulator | -0.029577 |
| SCAPER | S-phase cyclin A-associated protein in the ER | -0.0294467 |
| KRT8 | keratin 8, type II | -0.0291234 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0290569 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0290337 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0288968 |
| POU2F1 | POU class 2 homeobox 1 | -0.0288331 |
| EXOC4 | exocyst complex component 4 | -0.0286095 |
| SCLT1 | sodium channel and clathrin linker 1 | -0.0286072 |
| TNPO1 | transportin 1 | -0.0285729 |
| CSDE1 | cold shock domain containing E1, RNA-binding | -0.0285635 |
