| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | L-Thyroxine (sodium salt pentahydrate) perturbation in HOP62 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the L-Thyroxine (sodium salt pentahydrate)_HOP62 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TRIO | trio Rho guanine nucleotide exchange factor | 0.203149 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.134256 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.134171 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.122231 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.114874 |
| MT2A | metallothionein 2A | 0.113097 |
| MYO10 | myosin X | 0.107754 |
| RPS6 | ribosomal protein S6 | 0.107574 |
| CD44 | CD44 molecule (Indian blood group) | 0.104784 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0946813 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0926745 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0925754 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0874846 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0866683 |
| RFX8 | RFX family member 8, lacking RFX DNA binding domain | 0.0862947 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0816498 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0797785 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0769161 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0758545 |
| RRM2 | ribonucleotide reductase M2 | 0.0758187 |
| ENO1 | enolase 1, (alpha) | 0.0757232 |
| NAV1 | neuron navigator 1 | 0.0742487 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0739354 |
| CDCP1 | CUB domain containing protein 1 | 0.0730432 |
| RPS2 | ribosomal protein S2 | 0.070146 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0686771 |
| VEGFA | vascular endothelial growth factor A | 0.0652986 |
| FAM13A | family with sequence similarity 13, member A | 0.06475 |
| MSN | moesin | 0.0636541 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.063433 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0631446 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0627778 |
| CENPF | centromere protein F, 350/400kDa | 0.0616114 |
| ANKRD12 | ankyrin repeat domain 12 | 0.06109 |
| SEPTIN9 | septin 9 | 0.0599772 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0598589 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0594074 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0593495 |
| RPS3 | ribosomal protein S3 | 0.059116 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0589453 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0574522 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0566374 |
| RAI14 | retinoic acid induced 14 | 0.05657 |
| DTNA | dystrobrevin, alpha | 0.0546779 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0532602 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0510312 |
| TPM3 | tropomyosin 3 | 0.0506573 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0500405 |
| STC1 | stanniocalcin 1 | 0.0489441 |
| MAP1B | microtubule-associated protein 1B | 0.0487516 |
| ASPH | aspartate beta-hydroxylase | 0.0484986 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0481026 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0479245 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0478962 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.047645 |
| RPL12 | ribosomal protein L12 | 0.047606 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0471358 |
| RPL37A | ribosomal protein L37a | 0.0467717 |
| AXL | AXL receptor tyrosine kinase | 0.0459903 |
| RNF24 | ring finger protein 24 | 0.0457776 |
| NGLY1 | N-glycanase 1 | 0.0448356 |
| G0S2 | G0/G1 switch 2 | 0.0448157 |
| RPS8 | ribosomal protein S8 | 0.043696 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0434262 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0430907 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0425303 |
| MYO9B | myosin IXB | 0.0417516 |
| RPS12 | ribosomal protein S12 | 0.0404978 |
| EFNA5 | ephrin-A5 | 0.0402469 |
| TPI1 | triosephosphate isomerase 1 | 0.0396385 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0395836 |
| PCBP3 | poly(rC) binding protein 3 | 0.0393323 |
| TLN1 | talin 1 | 0.0389579 |
| LAMB3 | laminin, beta 3 | 0.0388936 |
| CLTC | clathrin, heavy chain (Hc) | 0.0386483 |
| CADM1 | cell adhesion molecule 1 | 0.0375919 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0375136 |
| TPX2 | TPX2, microtubule-associated | 0.037433 |
| RPL9 | ribosomal protein L9 | 0.0372106 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0368306 |
| SMAD3 | SMAD family member 3 | 0.0366182 |
| CAPRIN2 | caprin family member 2 | 0.0353622 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0353212 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0349656 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0348612 |
| RPL7 | ribosomal protein L7 | 0.0341722 |
| RPL37 | ribosomal protein L37 | 0.0336554 |
| TAC4 | tachykinin 4 (hemokinin) | 0.033219 |
| NECTIN2 | nectin cell adhesion molecule 2 | 0.0332002 |
| CHD1L | chromodomain helicase DNA binding protein 1-like | 0.032811 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0325945 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0325808 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0322297 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0322263 |
| RPL26 | ribosomal protein L26 | 0.0319973 |
| GOLGA4 | golgin A4 | 0.0317441 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.031582 |
| NDRG1 | N-myc downstream regulated 1 | 0.0314743 |
| DSG2 | desmoglein 2 | 0.0314512 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0314193 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.234338 |
| HMGA2 | high mobility group AT-hook 2 | -0.12057 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.115588 |
| CDH13 | cadherin 13 | -0.112353 |
| EGR1 | early growth response 1 | -0.108867 |
| VIM | vimentin | -0.0973782 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0915462 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0824377 |
| AHNAK | AHNAK nucleoprotein | -0.0706331 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0695918 |
| IGF2 | insulin-like growth factor 2 | -0.0630422 |
| LOX | lysyl oxidase | -0.0557929 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0532718 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0494106 |
| VCL | vinculin | -0.0422399 |
| FMN1 | formin 1 | -0.0386742 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0383237 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0382515 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0372818 |
| SBF2 | SET binding factor 2 | -0.0370437 |
| RPL35A | ribosomal protein L35a | -0.0345091 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0338715 |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 | -0.0335822 |
| HDLBP | high density lipoprotein binding protein | -0.03308 |
| COL5A1 | collagen, type V, alpha 1 | -0.0330428 |
| INHBA | inhibin, beta A | -0.032614 |
| COL7A1 | collagen, type VII, alpha 1 | -0.0325099 |
| NABP1 | nucleic acid binding protein 1 | -0.030055 |
| IL1B | interleukin 1, beta | -0.0296799 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0290002 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0286947 |
| TMSB10 | thymosin beta 10 | -0.0284043 |
| TENM2 | teneurin transmembrane protein 2 | -0.0283511 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.0280654 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0273529 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | -0.0269189 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0268773 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.02535 |
| COL1A1 | collagen, type I, alpha 1 | -0.0246826 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0244019 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0237782 |
| THBS1 | thrombospondin 1 | -0.0236498 |
| PLEC | plectin | -0.0232984 |
| IER3 | immediate early response 3 | -0.022811 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0226999 |
| FLNA | filamin A, alpha | -0.0223709 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0220537 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.0218704 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0217179 |
| MORF4L2 | mortality factor 4 like 2 | -0.0216865 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0215438 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0215094 |
| TUBB | tubulin, beta class I | -0.0209253 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0207878 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0202095 |
| GNAS | GNAS complex locus | -0.0199952 |
| ARF1 | ADP-ribosylation factor 1 | -0.0193798 |
| BSG | basigin (Ok blood group) | -0.0192021 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0192008 |
| COPA | coatomer protein complex, subunit alpha | -0.0190693 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0190019 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | -0.0185681 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0185346 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0185276 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0184812 |
| INTS6 | integrator complex subunit 6 | -0.0183569 |
| TMEM263 | transmembrane protein 263 | -0.01822 |
| GLG1 | golgi glycoprotein 1 | -0.018147 |
| AEBP2 | AE binding protein 2 | -0.0181332 |
| DENND1A | DENN/MADD domain containing 1A | -0.0181004 |
| CANX | calnexin | -0.0180549 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0179357 |
| EXOC6B | exocyst complex component 6B | -0.0178933 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0176559 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0176451 |
| PCNX4 | pecanex 4 | -0.0176064 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0172706 |
| NECTIN3 | nectin cell adhesion molecule 3 | -0.0171405 |
| PDGFRB | platelet-derived growth factor receptor, beta polypeptide | -0.0171113 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.017092 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.016813 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.016632 |
| EGFR | epidermal growth factor receptor | -0.016574 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0164692 |
| PRKCA | protein kinase C, alpha | -0.0164178 |
| SAMD3 | sterile alpha motif domain containing 3 | -0.0158218 |
| NF1 | neurofibromin 1 | -0.0157141 |
| GANAB | glucosidase, alpha; neutral AB | -0.0157123 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0156435 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0156372 |
| ZNF148 | zinc finger protein 148 | -0.0154695 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0154106 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0152711 |
| RPL34 | ribosomal protein L34 | -0.0152365 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.015206 |
| SAR1A | secretion associated, Ras related GTPase 1A | -0.0151981 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | -0.0150683 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0150451 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0146673 |
| ARF4 | ADP-ribosylation factor 4 | -0.014532 |
