| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | L-Thyroxine (sodium salt pentahydrate) perturbation in HT-29 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the L-Thyroxine (sodium salt pentahydrate)_HT-29 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NDRG1 | N-myc downstream regulated 1 | 0.0706065 |
| SAMD12 | sterile alpha motif domain containing 12 | 0.0524092 |
| RPS2 | ribosomal protein S2 | 0.0507094 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 0.0441171 |
| MYH14 | myosin, heavy chain 14, non-muscle | 0.0439812 |
| VEGFA | vascular endothelial growth factor A | 0.0395187 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0348976 |
| NTN4 | netrin 4 | 0.0342326 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.02787 |
| TMEM45B | transmembrane protein 45B | 0.0274371 |
| FAM13A | family with sequence similarity 13, member A | 0.0270393 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0260884 |
| RPS6 | ribosomal protein S6 | 0.0242092 |
| DSPP | dentin sialophosphoprotein | 0.0235774 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | 0.0223846 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.022254 |
| RIN2 | Ras and Rab interactor 2 | 0.0218937 |
| CLIC5 | chloride intracellular channel 5 | 0.0213488 |
| CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) | 0.0210815 |
| TNS1 | tensin 1 | 0.0210321 |
| RHPN2 | rhophilin, Rho GTPase binding protein 2 | 0.0209845 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0203474 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0202655 |
| DNM2 | dynamin 2 | 0.0198167 |
| TMC5 | transmembrane channel-like 5 | 0.0194194 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0189355 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0188777 |
| RBCK1 | RanBP-type and C3HC4-type zinc finger containing 1 | 0.0183776 |
| OPTN | optineurin | 0.0173035 |
| GOLM2 | golgi membrane protein 2 | 0.017198 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0168124 |
| BCL2L1 | BCL2-like 1 | 0.0162692 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.0162629 |
| CRYBG3 | beta-gamma crystallin domain containing 3 | 0.0162242 |
| TJP2 | tight junction protein 2 | 0.0158216 |
| RPL21 | ribosomal protein L21 | 0.0156304 |
| FUT11 | fucosyltransferase 11 (alpha (1,3) fucosyltransferase) | 0.0153976 |
| MTMR10 | myotubularin related protein 10 | 0.015378 |
| MYO10 | myosin X | 0.0152967 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0152597 |
| ARFGEF3 | ARFGEF family member 3 | 0.0152322 |
| UBXN4 | UBX domain protein 4 | 0.0149389 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0148467 |
| SLFN5 | schlafen family member 5 | 0.0146254 |
| SPIRE1 | spire-type actin nucleation factor 1 | 0.0145161 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.014407 |
| PLEKHA1 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 | 0.0143553 |
| WLS | wntless Wnt ligand secretion mediator | 0.0142625 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0141062 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0140988 |
| MMP24OS | MMP24 opposite strand | 0.0139769 |
| JMY | junction mediating and regulatory protein, p53 cofactor | 0.0139562 |
| RPL3 | ribosomal protein L3 | 0.0137593 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0137566 |
| MYO5B | myosin VB | 0.0137536 |
| SLK | STE20-like kinase | 0.0135403 |
| GNGT1 | guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 | 0.0135143 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.013502 |
| SULT2B1 | sulfotransferase family, cytosolic, 2B, member 1 | 0.013439 |
| FRY | furry homolog (Drosophila) | 0.0133831 |
| SLC40A1 | solute carrier family 40 (iron-regulated transporter), member 1 | 0.0133429 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0132835 |
| SRSF4 | serine/arginine-rich splicing factor 4 | 0.0131685 |
| TNS4 | tensin 4 | 0.013077 |
| ATP9A | ATPase, class II, type 9A | 0.0128952 |
| VASP | vasodilator-stimulated phosphoprotein | 0.0128659 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0127164 |
| HIVEP1 | human immunodeficiency virus type I enhancer binding protein 1 | 0.0126994 |
| GOLM1 | golgi membrane protein 1 | 0.0125745 |
| TRIM56 | tripartite motif containing 56 | 0.0125408 |
| ITPKC | inositol-trisphosphate 3-kinase C | 0.0123991 |
| APOL1 | apolipoprotein L, 1 | 0.0123281 |
| POTEF | POTE ankyrin domain family, member F | 0.0121367 |
| RBMS2 | RNA binding motif, single stranded interacting protein 2 | 0.0120599 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | 0.0118657 |
| NBR1 | neighbor of BRCA1 gene 1 | 0.0117613 |
| DIP2B | DIP2 disco-interacting protein 2 homolog B (Drosophila) | 0.0116829 |
| RPS18 | ribosomal protein S18 | 0.0116687 |
| TOP6BL | TOP6B like initiator of meiotic double strand breaks | 0.0115457 |
| TMEM51 | transmembrane protein 51 | 0.01136 |
| SH3BP2 | SH3-domain binding protein 2 | 0.011281 |
| OASL | 2'-5'-oligoadenylate synthetase-like | 0.0112636 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0112395 |
| UTRN | utrophin | 0.0111957 |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 | 0.0111648 |
| PGCKA1 | PDCD10 and GCKIII kinases associated 1 | 0.0110866 |
| USP24 | ubiquitin specific peptidase 24 | 0.0110198 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.010907 |
| FTL | ferritin, light polypeptide | 0.0109055 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0108388 |
| PKP4 | plakophilin 4 | 0.0108025 |
| GOLT1B | golgi transport 1B | 0.0107423 |
| SMAD3 | SMAD family member 3 | 0.0106747 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 | 0.0106656 |
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit | 0.0106638 |
| CREB3L1 | cAMP responsive element binding protein 3-like 1 | 0.0106397 |
| EPC1 | enhancer of polycomb homolog 1 (Drosophila) | 0.0106256 |
| PPA2 | pyrophosphatase (inorganic) 2 | 0.0106153 |
| CCSER1 | coiled-coil serine-rich protein 1 | 0.0104892 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | 0.0104599 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.18982 |
| PTMA | prothymosin, alpha | -0.179146 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.130269 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.121019 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.110575 |
| UBC | ubiquitin C | -0.103128 |
| TXNRD1 | thioredoxin reductase 1 | -0.0986532 |
| TMSB10 | thymosin beta 10 | -0.0966718 |
| RPS27A | ribosomal protein S27a | -0.0882862 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0877739 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0870424 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0799212 |
| KRT8 | keratin 8, type II | -0.0741839 |
| AHNAK | AHNAK nucleoprotein | -0.0733362 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0723918 |
| JUN | jun proto-oncogene | -0.0717577 |
| RPL23 | ribosomal protein L23 | -0.0712757 |
| ACTN4 | actinin, alpha 4 | -0.0703175 |
| ANXA2 | annexin A2 | -0.0697171 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0695897 |
| EZR | ezrin | -0.0671456 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0667715 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.06455 |
| ENO1 | enolase 1, (alpha) | -0.0625218 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.062438 |
| RPS3 | ribosomal protein S3 | -0.0535499 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0519871 |
| OGA | O-GlcNAcase | -0.051633 |
| AREG | amphiregulin | -0.0492291 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0487596 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0487404 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0482147 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0480084 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0476503 |
| CANX | calnexin | -0.0464081 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0456863 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0448542 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0445571 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0444389 |
| RPS24 | ribosomal protein S24 | -0.0443228 |
| TOP1 | topoisomerase (DNA) I | -0.0438568 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0430293 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0428873 |
| COG5 | component of oligomeric golgi complex 5 | -0.0421286 |
| S100A10 | S100 calcium binding protein A10 | -0.0417583 |
| SQSTM1 | sequestosome 1 | -0.0413845 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0401316 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0400892 |
| PCBP2 | poly(rC) binding protein 2 | -0.040069 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0399121 |
| HDLBP | high density lipoprotein binding protein | -0.0395007 |
| RPLP0 | ribosomal protein, large, P0 | -0.0392278 |
| FBXO32 | F-box protein 32 | -0.0390629 |
| KRT20 | keratin 20, type I | -0.0386788 |
| CALR | calreticulin | -0.0383982 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0378332 |
| IFRD1 | interferon-related developmental regulator 1 | -0.0377796 |
| EMP1 | epithelial membrane protein 1 | -0.0371169 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0371123 |
| TRIB1 | tribbles pseudokinase 1 | -0.0368458 |
| RPLP2 | ribosomal protein, large, P2 | -0.0358214 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0356126 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0354255 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0349299 |
| ZNF207 | zinc finger protein 207 | -0.0347607 |
| KLF6 | Kruppel-like factor 6 | -0.0346377 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0346184 |
| CSDE1 | cold shock domain containing E1, RNA-binding | -0.0345853 |
| RBM39 | RNA binding motif protein 39 | -0.0339847 |
| S100A6 | S100 calcium binding protein A6 | -0.0339591 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0336766 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0336558 |
| NF1 | neurofibromin 1 | -0.0335417 |
| RPL12 | ribosomal protein L12 | -0.0328475 |
| LAMB3 | laminin, beta 3 | -0.0328287 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0325273 |
| RHEB | Ras homolog enriched in brain | -0.0324765 |
| TES | testin LIM domain protein | -0.0321495 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0321039 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.031952 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.0318747 |
| PTK2 | protein tyrosine kinase 2 | -0.0313166 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0312098 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | -0.0311758 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0311281 |
| LYZ | lysozyme | -0.0310728 |
| RPS21 | ribosomal protein S21 | -0.0308728 |
| THOC2 | THO complex 2 | -0.030454 |
| LMNA | lamin A/C | -0.0304313 |
| RPLP1 | ribosomal protein, large, P1 | -0.0301945 |
| RPS5 | ribosomal protein S5 | -0.0301529 |
| VMP1 | vacuole membrane protein 1 | -0.0301053 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0300859 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0300821 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0300329 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.029994 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0299637 |
| RPS25 | ribosomal protein S25 | -0.0297807 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0296618 |
| IPO7 | importin 7 | -0.0294563 |
