| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | L-Thyroxine (sodium salt pentahydrate) perturbation in J82 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the L-Thyroxine (sodium salt pentahydrate)_J82 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NDRG1 | N-myc downstream regulated 1 | 0.0995162 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0911325 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0713713 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0650418 |
| NAV2 | neuron navigator 2 | 0.0638443 |
| POTEF | POTE ankyrin domain family, member F | 0.0573526 |
| INTS6 | integrator complex subunit 6 | 0.0546452 |
| DTNA | dystrobrevin, alpha | 0.0538579 |
| MSN | moesin | 0.0513087 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0499009 |
| PODXL | podocalyxin-like | 0.0458775 |
| VEGFA | vascular endothelial growth factor A | 0.0421823 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.040234 |
| RAI14 | retinoic acid induced 14 | 0.0397228 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0394335 |
| GALNT18 | polypeptide N-acetylgalactosaminyltransferase 18 | 0.0383283 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0381619 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0355473 |
| EGFR | epidermal growth factor receptor | 0.0355448 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.033494 |
| PHACTR1 | phosphatase and actin regulator 1 | 0.0331733 |
| ZNF841 | zinc finger protein 841 | 0.0330099 |
| RPS2 | ribosomal protein S2 | 0.0328322 |
| TPM3 | tropomyosin 3 | 0.0322778 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0315811 |
| ASPH | aspartate beta-hydroxylase | 0.0303464 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0301289 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0292568 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0286812 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0286314 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0270003 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0269865 |
| SEPTIN9 | septin 9 | 0.0267758 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0260991 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0256276 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0255089 |
| MCL1 | myeloid cell leukemia 1 | 0.025433 |
| VCL | vinculin | 0.0247528 |
| AFF3 | AF4/FMR2 family, member 3 | 0.0244093 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0239313 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.0239132 |
| ATXN1 | ataxin 1 | 0.023856 |
| TLN1 | talin 1 | 0.0235365 |
| ACTG1 | actin gamma 1 | 0.0232397 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0232221 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0231483 |
| SET | SET nuclear proto-oncogene | 0.0226903 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0224388 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0223504 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.02213 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0214524 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0213542 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0213053 |
| BRD2 | bromodomain containing 2 | 0.0212386 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0212222 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0212047 |
| FN1 | fibronectin 1 | 0.0207435 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0205149 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0202286 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0201523 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.0193111 |
| ADM | adrenomedullin | 0.0192125 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0188191 |
| HIVEP1 | human immunodeficiency virus type I enhancer binding protein 1 | 0.0187776 |
| ACTN1 | actinin, alpha 1 | 0.0186879 |
| FAM219A | family with sequence similarity 219, member A | 0.018651 |
| PRELID2 | PRELI domain containing 2 | 0.0185849 |
| PPP1R18 | protein phosphatase 1, regulatory subunit 18 | 0.0183738 |
| GPATCH2L | G patch domain containing 2-like | 0.0183647 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.017939 |
| FLNA | filamin A, alpha | 0.017932 |
| LDHA | lactate dehydrogenase A | 0.017857 |
| CAST | calpastatin | 0.0177657 |
| MYO10 | myosin X | 0.0177561 |
| CALD1 | caldesmon 1 | 0.0175211 |
| USP47 | ubiquitin specific peptidase 47 | 0.017326 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0172116 |
| CENPF | centromere protein F, 350/400kDa | 0.0171838 |
| MMP12 | matrix metallopeptidase 12 | 0.0171406 |
| IPO9 | importin 9 | 0.0170457 |
| FGFR1 | fibroblast growth factor receptor 1 | 0.0170226 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0170196 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.016975 |
| FNIP1 | folliculin interacting protein 1 | 0.0169036 |
| OPTN | optineurin | 0.0166871 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0163373 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.0163211 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0163088 |
| KLF12 | Kruppel-like factor 12 | 0.0160857 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0158915 |
| L1CAM | L1 cell adhesion molecule | 0.01587 |
| DSPP | dentin sialophosphoprotein | 0.0155889 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0154797 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0154084 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.015036 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0149805 |
| PRKCE | protein kinase C, epsilon | 0.0149487 |
| RUNX1 | runt-related transcription factor 1 | 0.0149309 |
| CABIN1 | calcineurin binding protein 1 | 0.0149018 |
| ARID1A | AT rich interactive domain 1A (SWI-like) | 0.0148921 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HLA-B | major histocompatibility complex, class I, B | -0.209593 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.197249 |
| FTL | ferritin, light polypeptide | -0.163719 |
| TXNRD1 | thioredoxin reductase 1 | -0.102259 |
| MT1X | metallothionein 1X | -0.101182 |
| DEK | DEK proto-oncogene | -0.0966353 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0912056 |
| TMSB10 | thymosin beta 10 | -0.0851205 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.083609 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0766136 |
| B2M | beta-2-microglobulin | -0.0718432 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0710532 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0618048 |
| PTMA | prothymosin, alpha | -0.0611102 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0605534 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0602854 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0594217 |
| TUBB | tubulin, beta class I | -0.058714 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0586858 |
| AHNAK | AHNAK nucleoprotein | -0.0580397 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0567539 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0549945 |
| RPL35A | ribosomal protein L35a | -0.0532522 |
| CALR | calreticulin | -0.0531741 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0520315 |
| HLA-A | major histocompatibility complex, class I, A | -0.0518646 |
| SULF1 | sulfatase 1 | -0.0512725 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0478416 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0474052 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0459452 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0457945 |
| TMSB4X | thymosin beta 4, X-linked | -0.0455711 |
| GNAS | GNAS complex locus | -0.0433309 |
| POSTN | periostin, osteoblast specific factor | -0.0432492 |
| PFN1 | profilin 1 | -0.0420205 |
| RPLP2 | ribosomal protein, large, P2 | -0.0418722 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0414167 |
| PLCB4 | phospholipase C, beta 4 | -0.0412694 |
| PPME1 | protein phosphatase methylesterase 1 | -0.040375 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0400587 |
| RPL35 | ribosomal protein L35 | -0.0397882 |
| RPL23 | ribosomal protein L23 | -0.0393018 |
| KRT7 | keratin 7, type II | -0.0388153 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0387037 |
| HMGB1 | high mobility group box 1 | -0.038243 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0380778 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0379301 |
| ARF4 | ADP-ribosylation factor 4 | -0.0371834 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0369508 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0368392 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0365156 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.0364172 |
| CTSD | cathepsin D | -0.0360441 |
| SLC12A8 | solute carrier family 12, member 8 | -0.0357181 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0355938 |
| RPL12 | ribosomal protein L12 | -0.0349424 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0348745 |
| KRT8 | keratin 8, type II | -0.0345568 |
| DPYD | dihydropyrimidine dehydrogenase | -0.033542 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0335095 |
| TPD52 | tumor protein D52 | -0.0332908 |
| KRT18 | keratin 18, type I | -0.033211 |
| RPL19 | ribosomal protein L19 | -0.0329771 |
| RPS6 | ribosomal protein S6 | -0.0328526 |
| UFM1 | ubiquitin-fold modifier 1 | -0.0327856 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | -0.0326216 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0322706 |
| TGFB2 | transforming growth factor, beta 2 | -0.032067 |
| CBX3 | chromobox homolog 3 | -0.0315254 |
| FOXP1 | forkhead box P1 | -0.0313366 |
| ZNF292 | zinc finger protein 292 | -0.0311582 |
| GLIS3 | GLIS family zinc finger 3 | -0.0308093 |
| HLA-C | major histocompatibility complex, class I, C | -0.0306674 |
| TMEM178B | transmembrane protein 178B | -0.0305957 |
| NOP58 | NOP58 ribonucleoprotein | -0.0305841 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0302907 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0300559 |
| RPL8 | ribosomal protein L8 | -0.0300117 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0293715 |
| RPS19 | ribosomal protein S19 | -0.0293181 |
| LIMA1 | LIM domain and actin binding 1 | -0.0292258 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0290353 |
| S100A10 | S100 calcium binding protein A10 | -0.0281141 |
| RLF | rearranged L-myc fusion | -0.0279818 |
| CANX | calnexin | -0.0279027 |
| CCBE1 | collagen and calcium binding EGF domains 1 | -0.0277143 |
| TPI1 | triosephosphate isomerase 1 | -0.0277003 |
| S100A6 | S100 calcium binding protein A6 | -0.0275307 |
| RPS21 | ribosomal protein S21 | -0.0274887 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0273642 |
| ATP5F1E | ATP synthase F1 subunit epsilon | -0.0273641 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0267435 |
| RPL32 | ribosomal protein L32 | -0.0265725 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.0265672 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.026472 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0264663 |
| UGGT2 | UDP-glucose glycoprotein glucosyltransferase 2 | -0.0264301 |
| VGLL3 | vestigial-like family member 3 | -0.0262409 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0262207 |
| IER3 | immediate early response 3 | -0.0260478 |
