| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | L-Thyroxine (sodium salt pentahydrate) perturbation in LOX-IMVI cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the L-Thyroxine (sodium salt pentahydrate)_LOX-IMVI drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.132627 |
| RPS2 | ribosomal protein S2 | 0.111853 |
| MSN | moesin | 0.106964 |
| EFNA5 | ephrin-A5 | 0.0982089 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0795982 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.077994 |
| MYO10 | myosin X | 0.0772773 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.0678279 |
| DTNA | dystrobrevin, alpha | 0.065624 |
| POTEF | POTE ankyrin domain family, member F | 0.0643689 |
| MCL1 | myeloid cell leukemia 1 | 0.0562254 |
| NAV1 | neuron navigator 1 | 0.0538292 |
| ASPH | aspartate beta-hydroxylase | 0.047469 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0466826 |
| CALD1 | caldesmon 1 | 0.0460717 |
| RPS6 | ribosomal protein S6 | 0.0450672 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.042171 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0415383 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.041473 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0396624 |
| TPM3 | tropomyosin 3 | 0.0394066 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0386444 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0384834 |
| RPS18 | ribosomal protein S18 | 0.0375741 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0361573 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0361248 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0361069 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0354296 |
| RPL21 | ribosomal protein L21 | 0.0352223 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0351334 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0346098 |
| RPL3 | ribosomal protein L3 | 0.0343608 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0316404 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0312527 |
| EGR1 | early growth response 1 | 0.0308771 |
| FRMD6 | FERM domain containing 6 | 0.0308637 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0303401 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0298256 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0293845 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0292866 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0292448 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | 0.0288485 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0276082 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0275084 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0260553 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.026007 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | 0.0259252 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.025358 |
| RPS12 | ribosomal protein S12 | 0.0253128 |
| ADAM32 | ADAM metallopeptidase domain 32 | 0.0248677 |
| RPS3 | ribosomal protein S3 | 0.0247515 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0247356 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0244595 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0241819 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0241632 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0239632 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0239255 |
| CCN2 | cellular communication network factor 2 | 0.0238708 |
| FNDC3B | fibronectin type III domain containing 3B | 0.023619 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0235576 |
| SETD5 | SET domain containing 5 | 0.0235487 |
| USP34 | ubiquitin specific peptidase 34 | 0.0235186 |
| FOSL1 | FOS-like antigen 1 | 0.0229201 |
| PCBP2 | poly(rC) binding protein 2 | 0.0224678 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0223149 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0222069 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0221539 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0219492 |
| TLN1 | talin 1 | 0.0214824 |
| CENPF | centromere protein F, 350/400kDa | 0.0208012 |
| FMNL2 | formin-like 2 | 0.0204715 |
| SKIL | SKI-like proto-oncogene | 0.0198484 |
| RND3 | Rho family GTPase 3 | 0.0196858 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0196671 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.019625 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0195323 |
| ANO6 | anoctamin 6 | 0.0194883 |
| TXNIP | thioredoxin interacting protein | 0.0189333 |
| VEGFA | vascular endothelial growth factor A | 0.0186055 |
| BRD2 | bromodomain containing 2 | 0.0185725 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0180668 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0180315 |
| MYO1B | myosin IB | 0.0178141 |
| KIAA1328 | KIAA1328 | 0.017549 |
| ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | 0.01732 |
| EFNB2 | ephrin-B2 | 0.0173001 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0172613 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0171924 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0170315 |
| DOCK1 | dedicator of cytokinesis 1 | 0.0169749 |
| INTS6 | integrator complex subunit 6 | 0.0169527 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0169419 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.016859 |
| SLC2A13 | solute carrier family 2 (facilitated glucose transporter), member 13 | 0.0167245 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0166722 |
| RPS17 | ribosomal protein S17 | 0.0166537 |
| RPS13 | ribosomal protein S13 | 0.0165737 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0164817 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0164699 |
| PRKCE | protein kinase C, epsilon | 0.0162812 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.328368 |
| TMSB10 | thymosin beta 10 | -0.109212 |
| AHNAK | AHNAK nucleoprotein | -0.10051 |
| ANXA2 | annexin A2 | -0.077599 |
| RPL35A | ribosomal protein L35a | -0.0714678 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0697471 |
| TXNRD1 | thioredoxin reductase 1 | -0.0663373 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0648047 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0642879 |
| LSAMP | limbic system-associated membrane protein | -0.0614497 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0592498 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.054676 |
| CAVIN1 | caveolae associated protein 1 | -0.0515131 |
| RPLP1 | ribosomal protein, large, P1 | -0.0513144 |
| C2CD2 | C2 calcium-dependent domain containing 2 | -0.0508481 |
| GNAS | GNAS complex locus | -0.0497107 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0455573 |
| CFAP251 | cilia and flagella associated protein 251 | -0.0440955 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0433826 |
| RPS24 | ribosomal protein S24 | -0.0401983 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.04016 |
| PGK1 | phosphoglycerate kinase 1 | -0.0385154 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0378379 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0350769 |
| TPM4 | tropomyosin 4 | -0.0334549 |
| RPL23 | ribosomal protein L23 | -0.0331475 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0329728 |
| ARHGAP18 | Rho GTPase activating protein 18 | -0.0329622 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0327134 |
| CD109 | CD109 molecule | -0.0326266 |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 | -0.0316995 |
| MAP4 | microtubule-associated protein 4 | -0.0314617 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.031026 |
| APP | amyloid beta (A4) precursor protein | -0.0307795 |
| PRRC2B | proline-rich coiled-coil 2B | -0.0306098 |
| NTM | neurotrimin | -0.0301499 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0301405 |
| SEPTIN7 | septin 7 | -0.0295872 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0295868 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0285962 |
| KIAA1217 | KIAA1217 | -0.0284607 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0280865 |
| CANX | calnexin | -0.0280438 |
| RLF | rearranged L-myc fusion | -0.027515 |
| WDR43 | WD repeat domain 43 | -0.0274834 |
| TNNC1 | troponin C type 1 (slow) | -0.0273717 |
| RPL4 | ribosomal protein L4 | -0.0273134 |
| WDR45B | WD repeat domain 45B | -0.0272055 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0267915 |
| OSMR | oncostatin M receptor | -0.026782 |
| COLEC10 | collectin sub-family member 10 (C-type lectin) | -0.0267442 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0266445 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0265409 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0264911 |
| NSD2 | nuclear receptor binding SET domain protein 2 | -0.0259781 |
| RPLP0 | ribosomal protein, large, P0 | -0.0257941 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0255323 |
| HLA-E | major histocompatibility complex, class I, E | -0.0253767 |
| TEX14 | testis expressed 14 | -0.0253418 |
| RPL34 | ribosomal protein L34 | -0.0251367 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0249559 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0247281 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0247022 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0246047 |
| RBM39 | RNA binding motif protein 39 | -0.024542 |
| RTN4 | reticulon 4 | -0.0244534 |
| RPS4X | ribosomal protein S4, X-linked | -0.0243903 |
| H1-0 | H1.0 linker histone | -0.0243142 |
| RPL8 | ribosomal protein L8 | -0.0243002 |
| IL13RA2 | interleukin 13 receptor, alpha 2 | -0.0240462 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0239671 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0236345 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0234133 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | -0.0231409 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0231368 |
| EMP1 | epithelial membrane protein 1 | -0.0225955 |
| RPL30 | ribosomal protein L30 | -0.0224489 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.022028 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0218363 |
| SSR3 | signal sequence receptor, gamma (translocon-associated protein gamma) | -0.0217043 |
| USP3 | ubiquitin specific peptidase 3 | -0.0217017 |
| HMGB1 | high mobility group box 1 | -0.021664 |
| MMP12 | matrix metallopeptidase 12 | -0.0212964 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0211626 |
| RPS20 | ribosomal protein S20 | -0.021155 |
| CTSB | cathepsin B | -0.0211188 |
| ACTN4 | actinin, alpha 4 | -0.0211175 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0209991 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0209117 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | -0.0208769 |
| NETO1 | neuropilin (NRP) and tolloid (TLL)-like 1 | -0.0207241 |
| FAM162A | family with sequence similarity 162, member A | -0.0207044 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0206701 |
| LASP1 | LIM and SH3 protein 1 | -0.0206494 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0206273 |
| FOXP1 | forkhead box P1 | -0.0206018 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0204831 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0202796 |
| ESM1 | endothelial cell-specific molecule 1 | -0.0201164 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0200773 |
