| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | L-Thyroxine (sodium salt pentahydrate) perturbation in LoVo cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the L-Thyroxine (sodium salt pentahydrate)_LoVo drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GOLGA4 | golgin A4 | 0.0745345 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0525743 |
| RPS2 | ribosomal protein S2 | 0.0502762 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0375799 |
| RPL3 | ribosomal protein L3 | 0.0362049 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0330174 |
| TXNRD1 | thioredoxin reductase 1 | 0.029784 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0280186 |
| TMF1 | TATA element modulatory factor 1 | 0.0273775 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 0.0270838 |
| RPS6 | ribosomal protein S6 | 0.0259416 |
| RNF145 | ring finger protein 145 | 0.0258779 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0255617 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.025027 |
| CALU | calumenin | 0.0249337 |
| PTEN | phosphatase and tensin homolog | 0.024766 |
| JMY | junction mediating and regulatory protein, p53 cofactor | 0.0237198 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0236623 |
| NKTR | natural killer cell triggering receptor | 0.0234261 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0232586 |
| RPS18 | ribosomal protein S18 | 0.0229024 |
| GALNT3 | polypeptide N-acetylgalactosaminyltransferase 3 | 0.0223086 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0216594 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0205695 |
| TMEM165 | transmembrane protein 165 | 0.0204397 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0203919 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0203423 |
| CLTC | clathrin, heavy chain (Hc) | 0.0203041 |
| ZNF292 | zinc finger protein 292 | 0.020297 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0201902 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0198845 |
| SRP54 | signal recognition particle 54kDa | 0.0197417 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | 0.0193381 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0192903 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.019237 |
| MON2 | MON2 homolog (S. cerevisiae) | 0.0190862 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | 0.0190452 |
| GOLT1B | golgi transport 1B | 0.0187001 |
| COG6 | component of oligomeric golgi complex 6 | 0.0184065 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.017275 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0172479 |
| SETD5 | SET domain containing 5 | 0.0171628 |
| ARRDC3 | arrestin domain containing 3 | 0.0170179 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | 0.016816 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0166931 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0166799 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.016602 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0164671 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0163578 |
| KDM7A | lysine (K)-specific demethylase 7A | 0.0163449 |
| RPL21 | ribosomal protein L21 | 0.0161694 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.01611 |
| NDRG1 | N-myc downstream regulated 1 | 0.016044 |
| COPA | coatomer protein complex, subunit alpha | 0.0159879 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0159041 |
| SEC24A | SEC24 family member A | 0.0158622 |
| TFG | TRK-fused gene | 0.0158025 |
| PCBP2 | poly(rC) binding protein 2 | 0.0156374 |
| PKP2 | plakophilin 2 | 0.0155419 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.015489 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0152121 |
| RPL7 | ribosomal protein L7 | 0.0151807 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0150302 |
| SUCO | SUN domain containing ossification factor | 0.0149879 |
| PGM3 | phosphoglucomutase 3 | 0.0146076 |
| OGA | O-GlcNAcase | 0.0143893 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.014369 |
| PRRC1 | proline-rich coiled-coil 1 | 0.0143288 |
| USP3 | ubiquitin specific peptidase 3 | 0.0140753 |
| TPM3 | tropomyosin 3 | 0.0139598 |
| PCM1 | pericentriolar material 1 | 0.0138959 |
| GLG1 | golgi glycoprotein 1 | 0.0138248 |
| TBC1D15 | TBC1 domain family, member 15 | 0.0138243 |
| CLINT1 | clathrin interactor 1 | 0.0137816 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0136183 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0134929 |
| RLF | rearranged L-myc fusion | 0.0133383 |
| SNX13 | sorting nexin 13 | 0.0133341 |
| UBXN4 | UBX domain protein 4 | 0.0131691 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | 0.0131189 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0130639 |
| UGT1A6 | UDP glucuronosyltransferase 1 family, polypeptide A6 | 0.0130048 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0129948 |
| POTEF | POTE ankyrin domain family, member F | 0.0129279 |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | 0.0129264 |
| CDK19 | cyclin-dependent kinase 19 | 0.0129199 |
| PDE8A | phosphodiesterase 8A | 0.0128565 |
| SLTM | SAFB-like, transcription modulator | 0.0127686 |
| UBN2 | ubinuclein 2 | 0.0127227 |
| RNF43 | ring finger protein 43 | 0.0127101 |
| TMEM41B | transmembrane protein 41B | 0.0126344 |
| SON | SON DNA binding protein | 0.0124845 |
| LRRC1 | leucine rich repeat containing 1 | 0.012481 |
| SCAF11 | SR-related CTD-associated factor 11 | 0.0124791 |
| HERC1 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 | 0.0124373 |
| SEC16A | SEC16 homolog A (S. cerevisiae) | 0.0124361 |
| CUL3 | cullin 3 | 0.0123923 |
| ZNF638 | zinc finger protein 638 | 0.0123716 |
| SFXN1 | sideroflexin 1 | 0.0123475 |
| TNRC6A | trinucleotide repeat containing 6A | 0.0122293 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.149271 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.135367 |
| ANXA2 | annexin A2 | -0.0847686 |
| MYO1E | myosin IE | -0.0844797 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0807525 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0774306 |
| LMO7 | LIM domain 7 | -0.0737697 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0710263 |
| LAMB3 | laminin, beta 3 | -0.0685638 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0649972 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0620679 |
| VCL | vinculin | -0.0615838 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0607964 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.059338 |
| MSI2 | musashi RNA-binding protein 2 | -0.0591062 |
| FLNB | filamin B, beta | -0.0590676 |
| SLCO1B3-SLCO1B7 | SLCO1B3-SLCO1B7 readthrough | -0.0584213 |
| SP100 | SP100 nuclear antigen | -0.0576967 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0567241 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0566021 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0563942 |
| RIGI | RNA sensor RIG-I | -0.0554928 |
| ACTN4 | actinin, alpha 4 | -0.0535684 |
| FRMD5 | FERM domain containing 5 | -0.0533187 |
| INTS6 | integrator complex subunit 6 | -0.0530028 |
| PTPRB | protein tyrosine phosphatase, receptor type, B | -0.0519446 |
| TMSB10 | thymosin beta 10 | -0.0515852 |
| KRT8 | keratin 8, type II | -0.050663 |
| RPL34 | ribosomal protein L34 | -0.0500303 |
| RPLP1 | ribosomal protein, large, P1 | -0.0477091 |
| KRT18 | keratin 18, type I | -0.0476724 |
| RPS24 | ribosomal protein S24 | -0.0476603 |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 | -0.0466121 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0463947 |
| RPL35A | ribosomal protein L35a | -0.0451493 |
| SERINC5 | serine incorporator 5 | -0.0451418 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0444107 |
| EZR | ezrin | -0.0442405 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0440927 |
| MX1 | MX dynamin-like GTPase 1 | -0.0431042 |
| CUX1 | cut-like homeobox 1 | -0.0430068 |
| RPLP0 | ribosomal protein, large, P0 | -0.0423567 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.042103 |
| HLA-B | major histocompatibility complex, class I, B | -0.0415898 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0412983 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0408251 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0407829 |
| ACTG1 | actin gamma 1 | -0.0398714 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0395655 |
| AOPEP | aminopeptidase O (putative) | -0.039527 |
| SPINK13 | serine peptidase inhibitor, Kazal type 13 (putative) | -0.0378286 |
| DSG3 | desmoglein 3 | -0.0368244 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | -0.0366177 |
| RNF213 | ring finger protein 213 | -0.0364901 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0363913 |
| LAMA4 | laminin, alpha 4 | -0.0352954 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.034571 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0343393 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0340615 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | -0.0340608 |
| CATSPERB | catsper channel auxiliary subunit beta | -0.0337434 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | -0.0333884 |
| P3H2 | prolyl 3-hydroxylase 2 | -0.0328994 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0327545 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0325003 |
| PALLD | palladin, cytoskeletal associated protein | -0.0324538 |
| RIMKLB | ribosomal modification protein rimK-like family member B | -0.0320159 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0317955 |
| PTMA | prothymosin, alpha | -0.031224 |
| FBXO11 | F-box protein 11 | -0.0308418 |
| RPS25 | ribosomal protein S25 | -0.0301547 |
| MYH14 | myosin, heavy chain 14, non-muscle | -0.0299321 |
| OXSR1 | oxidative stress responsive 1 | -0.0298849 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0297609 |
| LRRC23 | leucine rich repeat containing 23 | -0.0292542 |
| MCU | mitochondrial calcium uniporter | -0.0290194 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0284109 |
| SQSTM1 | sequestosome 1 | -0.0283964 |
| EXOC4 | exocyst complex component 4 | -0.0283881 |
| DENND1A | DENN/MADD domain containing 1A | -0.0283398 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0281296 |
| XAF1 | XIAP associated factor 1 | -0.0276298 |
| RAD51B | RAD51 paralog B | -0.0274787 |
| LDHA | lactate dehydrogenase A | -0.0274319 |
| PLSCR1 | phospholipid scramblase 1 | -0.0273687 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0273433 |
| AHNAK | AHNAK nucleoprotein | -0.027196 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0271805 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | -0.0270707 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0270362 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 | -0.0268326 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.026816 |
| TSPAN8 | tetraspanin 8 | -0.026784 |
| IFRD1 | interferon-related developmental regulator 1 | -0.0262376 |
| NPSR1 | neuropeptide S receptor 1 | -0.025862 |
| S100A6 | S100 calcium binding protein A6 | -0.0256135 |
| OGDH | oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) | -0.0255987 |
| CTBP2 | C-terminal binding protein 2 | -0.0254283 |
| UBAP2 | ubiquitin associated protein 2 | -0.0250163 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.0247391 |
