| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | L-Thyroxine (sodium salt pentahydrate) perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the L-Thyroxine (sodium salt pentahydrate)_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0810649 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0714265 |
| GOLGA4 | golgin A4 | 0.0697568 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0664542 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0616312 |
| DPYSL3 | dihydropyrimidinase-like 3 | 0.0546436 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0521781 |
| NAV2 | neuron navigator 2 | 0.0521085 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.05081 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0505735 |
| NRP1 | neuropilin 1 | 0.047604 |
| NGLY1 | N-glycanase 1 | 0.0472308 |
| SMAD3 | SMAD family member 3 | 0.0465081 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0429351 |
| FAM13A | family with sequence similarity 13, member A | 0.0414471 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0407418 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0397576 |
| ADD3 | adducin 3 (gamma) | 0.0396975 |
| SETD5 | SET domain containing 5 | 0.0385788 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0374164 |
| PARP8 | poly (ADP-ribose) polymerase family, member 8 | 0.0372346 |
| ATP13A3 | ATPase type 13A3 | 0.035557 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0349956 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0349901 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0344608 |
| CD109 | CD109 molecule | 0.0343372 |
| GPAT3 | glycerol-3-phosphate acyltransferase 3 | 0.0339866 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.0339172 |
| OPTN | optineurin | 0.0338949 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0336827 |
| KYNU | kynureninase | 0.0335636 |
| VEGFA | vascular endothelial growth factor A | 0.0334597 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0331633 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0330038 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0329944 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0312199 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.0310352 |
| PLEKHA1 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 | 0.0309083 |
| FAM3C | family with sequence similarity 3, member C | 0.0308121 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0308051 |
| MEF2A | myocyte enhancer factor 2A | 0.0304674 |
| RAB27B | RAB27B, member RAS oncogene family | 0.0302456 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0296675 |
| RNF145 | ring finger protein 145 | 0.0296522 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0292676 |
| PFKP | phosphofructokinase, platelet | 0.0289976 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.028967 |
| YEATS2 | YEATS domain containing 2 | 0.0287571 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | 0.0277131 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0275302 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0274083 |
| ZNRF1 | zinc and ring finger 1, E3 ubiquitin protein ligase | 0.0271639 |
| ARHGAP42 | Rho GTPase activating protein 42 | 0.0266437 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0264586 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0264314 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0264016 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0263112 |
| PIAS2 | protein inhibitor of activated STAT, 2 | 0.0263101 |
| ZNF638 | zinc finger protein 638 | 0.0261026 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0259857 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0259352 |
| RNF24 | ring finger protein 24 | 0.0254545 |
| ITGAV | integrin, alpha V | 0.0250277 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0248691 |
| ECE1 | endothelin converting enzyme 1 | 0.0247915 |
| RARB | retinoic acid receptor, beta | 0.0245634 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.024545 |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.0244961 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.0242188 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0239933 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0239297 |
| ARRDC3 | arrestin domain containing 3 | 0.0238705 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0238267 |
| DAB2 | Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) | 0.023392 |
| ANKH | ANKH inorganic pyrophosphate transport regulator | 0.0233124 |
| AMPD3 | adenosine monophosphate deaminase 3 | 0.0231181 |
| LRRC49 | leucine rich repeat containing 49 | 0.0231042 |
| TENT4A | terminal nucleotidyltransferase 4A | 0.0229882 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0228495 |
| PCBP2 | poly(rC) binding protein 2 | 0.022798 |
| OGA | O-GlcNAcase | 0.0227435 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0227426 |
| RUNX1 | runt-related transcription factor 1 | 0.022666 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0224831 |
| PRSS3 | protease, serine, 3 | 0.0224157 |
| POM121C | POM121 transmembrane nucleoporin C | 0.022364 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0222702 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.022219 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | 0.0219502 |
| SMAD4 | SMAD family member 4 | 0.0217129 |
| MYO1E | myosin IE | 0.0216027 |
| PIP4K2A | phosphatidylinositol-5-phosphate 4-kinase, type II, alpha | 0.0215625 |
| DSE | dermatan sulfate epimerase | 0.021525 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0214675 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0214393 |
| SLTM | SAFB-like, transcription modulator | 0.0213757 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0213063 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0209116 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0207813 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | 0.0207125 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.151296 |
| TMSB10 | thymosin beta 10 | -0.149296 |
| VIM | vimentin | -0.112162 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.107287 |
| HMGA2 | high mobility group AT-hook 2 | -0.101387 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.100261 |
| NRG1 | neuregulin 1 | -0.0855882 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0733188 |
| LOX | lysyl oxidase | -0.0720906 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0707842 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0675329 |
| FAM20C | family with sequence similarity 20, member C | -0.0641854 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.062415 |
| MSRB3 | methionine sulfoxide reductase B3 | -0.0623824 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0614242 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0593671 |
| AADAC | arylacetamide deacetylase | -0.0542256 |
| CDH13 | cadherin 13 | -0.0529133 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.0511878 |
| PTMA | prothymosin, alpha | -0.0503047 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0498815 |
| SP100 | SP100 nuclear antigen | -0.0496894 |
| FN1 | fibronectin 1 | -0.0488892 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0487889 |
| STC1 | stanniocalcin 1 | -0.0479243 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0472251 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0470705 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0458388 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0455857 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0451753 |
| MTSS1 | metastasis suppressor 1 | -0.043375 |
| EGR1 | early growth response 1 | -0.0426045 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0417413 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0402418 |
| IER3 | immediate early response 3 | -0.0395049 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0394275 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | -0.0385411 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0382707 |
| CDK14 | cyclin-dependent kinase 14 | -0.0375276 |
| EFCAB13 | EF-hand calcium binding domain 13 | -0.0374893 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0374595 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0373856 |
| S100A6 | S100 calcium binding protein A6 | -0.0372066 |
| ZNF804A | zinc finger protein 804A | -0.0365924 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0362269 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0361843 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0360174 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0358442 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0354577 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0351631 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0350699 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0350409 |
| FBN1 | fibrillin 1 | -0.0349231 |
| CLIC4 | chloride intracellular channel 4 | -0.0342544 |
| HLA-B | major histocompatibility complex, class I, B | -0.0338107 |
| THBD | thrombomodulin | -0.0334903 |
| RPS24 | ribosomal protein S24 | -0.0315991 |
| GLCCI1 | glucocorticoid induced 1 | -0.0312593 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0305906 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0305544 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0302658 |
| IL1B | interleukin 1, beta | -0.0294913 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0294696 |
| VCL | vinculin | -0.0292511 |
| INTS6 | integrator complex subunit 6 | -0.0292345 |
| CP | ceruloplasmin (ferroxidase) | -0.0288546 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0286857 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0285805 |
| RIGI | RNA sensor RIG-I | -0.0283907 |
| EREG | epiregulin | -0.0282235 |
| GLIS3 | GLIS family zinc finger 3 | -0.028206 |
| TMSB4X | thymosin beta 4, X-linked | -0.0279954 |
| TGFB1 | transforming growth factor, beta 1 | -0.0277509 |
| ATG7 | autophagy related 7 | -0.0275083 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0274365 |
| RPS21 | ribosomal protein S21 | -0.0273851 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | -0.0272773 |
| RPL34 | ribosomal protein L34 | -0.0268522 |
| TMEM263 | transmembrane protein 263 | -0.0268396 |
| ANXA2 | annexin A2 | -0.026828 |
| NLK | nemo-like kinase | -0.026802 |
| MT2A | metallothionein 2A | -0.0267278 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0266076 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0264761 |
| CUX1 | cut-like homeobox 1 | -0.0264319 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0260116 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0260063 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0259256 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | -0.0258586 |
| ATXN1 | ataxin 1 | -0.0257616 |
| PRSS23 | protease, serine, 23 | -0.0254368 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.0252603 |
| S100A10 | S100 calcium binding protein A10 | -0.0252122 |
| B2M | beta-2-microglobulin | -0.0251549 |
| DNER | delta/notch-like EGF repeat containing | -0.0250771 |
| ENOSF1 | enolase superfamily member 1 | -0.025046 |
| DIAPH2 | diaphanous-related formin 2 | -0.0247349 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0245218 |
| ASPH | aspartate beta-hydroxylase | -0.0243708 |
| CLMP | CXADR-like membrane protein | -0.0243182 |
