| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | L-Thyroxine (sodium salt pentahydrate) perturbation in NCI-H23 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the L-Thyroxine (sodium salt pentahydrate)_NCI-H23 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.335033 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.107206 |
| YBX3 | Y box binding protein 3 | 0.0686968 |
| TPM3 | tropomyosin 3 | 0.0681574 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0557547 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0528355 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0507503 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0434266 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.043272 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0424112 |
| CCNL1 | cyclin L1 | 0.0395043 |
| CTTNBP2NL | CTTNBP2 N-terminal like | 0.037121 |
| FMNL2 | formin-like 2 | 0.03565 |
| CDK17 | cyclin-dependent kinase 17 | 0.0350461 |
| RUSC2 | RUN and SH3 domain containing 2 | 0.0342739 |
| ANKRD36 | ankyrin repeat domain 36 | 0.034183 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.033955 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0338479 |
| CDCP1 | CUB domain containing protein 1 | 0.0336347 |
| PDE10A | phosphodiesterase 10A | 0.032858 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0323696 |
| STC1 | stanniocalcin 1 | 0.0318577 |
| EML4 | echinoderm microtubule associated protein like 4 | 0.0315379 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0314019 |
| MMP12 | matrix metallopeptidase 12 | 0.0312507 |
| LATS2 | large tumor suppressor kinase 2 | 0.0302543 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0300367 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0300351 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0300258 |
| TMEM165 | transmembrane protein 165 | 0.029676 |
| MSN | moesin | 0.0295376 |
| POTEF | POTE ankyrin domain family, member F | 0.0293551 |
| RPS2 | ribosomal protein S2 | 0.0292266 |
| RNF145 | ring finger protein 145 | 0.0282379 |
| ATP11A | ATPase, class VI, type 11A | 0.0277841 |
| CHD1L | chromodomain helicase DNA binding protein 1-like | 0.026788 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0260089 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.025604 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0255848 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0253779 |
| TBK1 | TANK-binding kinase 1 | 0.0246619 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0245108 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.024328 |
| ATP13A3 | ATPase type 13A3 | 0.024282 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0240243 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | 0.0237998 |
| ANO6 | anoctamin 6 | 0.0232308 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0230962 |
| VMP1 | vacuole membrane protein 1 | 0.0229305 |
| PHC2 | polyhomeotic homolog 2 (Drosophila) | 0.0228575 |
| SET | SET nuclear proto-oncogene | 0.022549 |
| OSMR | oncostatin M receptor | 0.0225376 |
| RAP1B | RAP1B, member of RAS oncogene family | 0.0224527 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0223484 |
| MARCHF4 | membrane associated ring-CH-type finger 4 | 0.0221401 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0218665 |
| NKTR | natural killer cell triggering receptor | 0.0218023 |
| PCBP2 | poly(rC) binding protein 2 | 0.021385 |
| USP47 | ubiquitin specific peptidase 47 | 0.020757 |
| AFF3 | AF4/FMR2 family, member 3 | 0.02074 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.02063 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.02056 |
| SNX9 | sorting nexin 9 | 0.0205292 |
| DPYSL2 | dihydropyrimidinase-like 2 | 0.0198828 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0196326 |
| CHIC2 | cysteine-rich hydrophobic domain 2 | 0.0195929 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | 0.019591 |
| CAPRIN2 | caprin family member 2 | 0.0195215 |
| KMT2D | lysine (K)-specific methyltransferase 2D | 0.0194272 |
| CTTN | cortactin | 0.0192531 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0191311 |
| VEZT | vezatin, adherens junctions transmembrane protein | 0.0191116 |
| CALD1 | caldesmon 1 | 0.019099 |
| RPL3 | ribosomal protein L3 | 0.0187056 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0184824 |
| ITGB5 | integrin, beta 5 | 0.0178306 |
| PNN | pinin, desmosome associated protein | 0.0177923 |
| TMEM41B | transmembrane protein 41B | 0.017738 |
| ANP32E | acidic (leucine-rich) nuclear phosphoprotein 32 family, member E | 0.0175186 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0174956 |
| MT2A | metallothionein 2A | 0.0174525 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0173645 |
| CDYL | chromodomain protein, Y-like | 0.0172111 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0171873 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0171821 |
| RTN4 | reticulon 4 | 0.0171159 |
| VPS54 | vacuolar protein sorting 54 homolog (S. cerevisiae) | 0.0168308 |
| DENR | density-regulated protein | 0.0165651 |
| LUZP1 | leucine zipper protein 1 | 0.0163792 |
| TLN1 | talin 1 | 0.0162699 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.0161738 |
| SNX14 | sorting nexin 14 | 0.0161555 |
| DNMBP | dynamin binding protein | 0.0160734 |
| KDM7A | lysine (K)-specific demethylase 7A | 0.0159146 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.0159136 |
| TCIM | transcriptional and immune response regulator | 0.0157582 |
| FERMT2 | fermitin family member 2 | 0.0156878 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0156243 |
| BLTP1 | bridge-like lipid transfer protein family member 1 | 0.0155652 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0154653 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.224963 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.185456 |
| VIM | vimentin | -0.122767 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.117361 |
| TMSB10 | thymosin beta 10 | -0.100505 |
| RPL35A | ribosomal protein L35a | -0.0988138 |
| PTMA | prothymosin, alpha | -0.0804279 |
| RPL23 | ribosomal protein L23 | -0.0709856 |
| AHNAK | AHNAK nucleoprotein | -0.0698027 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0645152 |
| RPLP0 | ribosomal protein, large, P0 | -0.0593022 |
| RPLP1 | ribosomal protein, large, P1 | -0.0579089 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0564854 |
| RPS21 | ribosomal protein S21 | -0.0530979 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0523494 |
| GNAS | GNAS complex locus | -0.051171 |
| RPL12 | ribosomal protein L12 | -0.050623 |
| RPL26 | ribosomal protein L26 | -0.0505828 |
| RPL37 | ribosomal protein L37 | -0.0495188 |
| H1-0 | H1.0 linker histone | -0.0494005 |
| CSDE1 | cold shock domain containing E1, RNA-binding | -0.0483925 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0469665 |
| RPL19 | ribosomal protein L19 | -0.0457284 |
| RPL34 | ribosomal protein L34 | -0.0452634 |
| RPS8 | ribosomal protein S8 | -0.0451027 |
| MKI67 | marker of proliferation Ki-67 | -0.0444691 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0440157 |
| RPL31 | ribosomal protein L31 | -0.0425983 |
| RPL32 | ribosomal protein L32 | -0.0424601 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0420287 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0413463 |
| RPS29 | ribosomal protein S29 | -0.041073 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | -0.0409866 |
| KDM4B | lysine (K)-specific demethylase 4B | -0.0409139 |
| RPS4X | ribosomal protein S4, X-linked | -0.0408104 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0403213 |
| RPS15 | ribosomal protein S15 | -0.0388975 |
| FUS | FUS RNA binding protein | -0.0384798 |
| RPL37A | ribosomal protein L37a | -0.0383896 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.0379355 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | -0.0372202 |
| CANX | calnexin | -0.037186 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0369622 |
| RPS27A | ribosomal protein S27a | -0.0367045 |
| RPS27 | ribosomal protein S27 | -0.0366457 |
| INTS6 | integrator complex subunit 6 | -0.036435 |
| RPL5 | ribosomal protein L5 | -0.0361468 |
| RPS24 | ribosomal protein S24 | -0.0358999 |
| ACTG1 | actin gamma 1 | -0.0358973 |
| LRRC23 | leucine rich repeat containing 23 | -0.0358617 |
| FTL | ferritin, light polypeptide | -0.0357914 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.0355513 |
| SRP72 | signal recognition particle 72kDa | -0.0351529 |
| RACK1 | receptor for activated C kinase 1 | -0.0350417 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0349048 |
| RPL36 | ribosomal protein L36 | -0.033975 |
| CAVIN1 | caveolae associated protein 1 | -0.033572 |
| RPS25 | ribosomal protein S25 | -0.0335484 |
| RPS19 | ribosomal protein S19 | -0.033521 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0334916 |
| RPS16 | ribosomal protein S16 | -0.0332879 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0326584 |
| RNF213 | ring finger protein 213 | -0.0323915 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0321556 |
| UBB | ubiquitin B | -0.0320156 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0319638 |
| TUBB | tubulin, beta class I | -0.0318437 |
| RPL4 | ribosomal protein L4 | -0.031387 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0313438 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | -0.0311604 |
| ADAR | adenosine deaminase, RNA-specific | -0.0310227 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0309851 |
| RPL35 | ribosomal protein L35 | -0.0307865 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0305451 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0302852 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.030112 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0300651 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0293815 |
| RPL8 | ribosomal protein L8 | -0.0293436 |
| CCND1 | cyclin D1 | -0.0291894 |
| SMAD3 | SMAD family member 3 | -0.0291673 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.029077 |
| ZNF609 | zinc finger protein 609 | -0.028803 |
| GOLGB1 | golgin B1 | -0.0287915 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.028602 |
| UBC | ubiquitin C | -0.0282856 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0282311 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.0282282 |
| TAOK1 | TAO kinase 1 | -0.0281808 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0281407 |
| MED13 | mediator complex subunit 13 | -0.0280837 |
| RPS3 | ribosomal protein S3 | -0.0280522 |
| ANXA2 | annexin A2 | -0.0280298 |
| RAD21 | RAD21 homolog (S. pombe) | -0.027882 |
| WNT2B | wingless-type MMTV integration site family, member 2B | -0.0276306 |
| NACA | nascent polypeptide-associated complex alpha subunit | -0.0273105 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.0267247 |
| ARF1 | ADP-ribosylation factor 1 | -0.0261535 |
| CLIP1 | CAP-GLY domain containing linker protein 1 | -0.0260264 |
| HLA-B | major histocompatibility complex, class I, B | -0.0259863 |
