| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | L-Thyroxine (sodium salt pentahydrate) perturbation in NCI-H2347 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the L-Thyroxine (sodium salt pentahydrate)_NCI-H2347 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.161826 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0965047 |
| LAMC2 | laminin, gamma 2 | 0.0842028 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0735296 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0708767 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0680239 |
| EFNA5 | ephrin-A5 | 0.064952 |
| DSPP | dentin sialophosphoprotein | 0.0603101 |
| LMO7 | LIM domain 7 | 0.0579231 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.056822 |
| FN1 | fibronectin 1 | 0.0519717 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0475873 |
| FBXO32 | F-box protein 32 | 0.0465925 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0463187 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0452366 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.044978 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0408959 |
| PLEC | plectin | 0.0387181 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0382681 |
| AHNAK | AHNAK nucleoprotein | 0.0375155 |
| GOLGB1 | golgin B1 | 0.0366797 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0362515 |
| DSG2 | desmoglein 2 | 0.0352206 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0346003 |
| TMSB4X | thymosin beta 4, X-linked | 0.033476 |
| CANX | calnexin | 0.0321353 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0308597 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0304073 |
| VCL | vinculin | 0.0298868 |
| CLTC | clathrin, heavy chain (Hc) | 0.0298623 |
| LAMB3 | laminin, beta 3 | 0.0295713 |
| ERBIN | erbb2 interacting protein | 0.0295514 |
| DST | dystonin | 0.0285585 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0282896 |
| CAB39 | calcium binding protein 39 | 0.0281136 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.02807 |
| MYO1E | myosin IE | 0.0276596 |
| FNIP1 | folliculin interacting protein 1 | 0.027239 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0270848 |
| MYO5B | myosin VB | 0.0263879 |
| MAP1B | microtubule-associated protein 1B | 0.025682 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0255708 |
| ATXN1 | ataxin 1 | 0.0250436 |
| NR3C2 | nuclear receptor subfamily 3, group C, member 2 | 0.0248899 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0247889 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0243983 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0239475 |
| HDLBP | high density lipoprotein binding protein | 0.0239408 |
| RPS2 | ribosomal protein S2 | 0.0239312 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0238844 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.023835 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0238233 |
| DUSP10 | dual specificity phosphatase 10 | 0.0238204 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0237164 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.02369 |
| RAI14 | retinoic acid induced 14 | 0.0234993 |
| SVIL | supervillin | 0.0231892 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0231855 |
| NAV2 | neuron navigator 2 | 0.0230551 |
| PATJ | PATJ crumbs cell polarity complex component | 0.0229982 |
| RCOR1 | REST corepressor 1 | 0.0225549 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.0224528 |
| ETV6 | ets variant 6 | 0.0223667 |
| DTNA | dystrobrevin, alpha | 0.0223177 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.0221009 |
| ARHGAP20 | Rho GTPase activating protein 20 | 0.0220277 |
| PGBD5 | piggyBac transposable element derived 5 | 0.0219497 |
| VGLL3 | vestigial-like family member 3 | 0.0211696 |
| CEP350 | centrosomal protein 350kDa | 0.0211167 |
| RPL4 | ribosomal protein L4 | 0.0209608 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0208911 |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 | 0.0207922 |
| RPL14 | ribosomal protein L14 | 0.0207209 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0206962 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0204129 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0202731 |
| FBXO34 | F-box protein 34 | 0.0197087 |
| MICAL3 | microtubule associated monooxygenase, calponin and LIM domain containing 3 | 0.0196499 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0196161 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0195285 |
| TPM3 | tropomyosin 3 | 0.0193053 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0192311 |
| HMGB2 | high mobility group box 2 | 0.0191837 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0191335 |
| RBM47 | RNA binding motif protein 47 | 0.0190662 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0189929 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0189866 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0188201 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0185085 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0184773 |
| TPM4 | tropomyosin 4 | 0.018185 |
| SH3RF1 | SH3 domain containing ring finger 1 | 0.0178815 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0178404 |
| TMF1 | TATA element modulatory factor 1 | 0.0177486 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0176459 |
| PALLD | palladin, cytoskeletal associated protein | 0.0175174 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0174618 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0173605 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0173316 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | 0.0172663 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.159529 |
| NDRG1 | N-myc downstream regulated 1 | -0.109489 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0944053 |
| FTL | ferritin, light polypeptide | -0.0834433 |
| HMGA1 | high mobility group AT-hook 1 | -0.0775357 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0747489 |
| TMSB10 | thymosin beta 10 | -0.0638981 |
| S100A6 | S100 calcium binding protein A6 | -0.058797 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0581401 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0580932 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0449875 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0420372 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0413812 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0409056 |
| RPL35A | ribosomal protein L35a | -0.0393244 |
| MT2A | metallothionein 2A | -0.0388469 |
| FOSL1 | FOS-like antigen 1 | -0.0365455 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | -0.0353478 |
| FAM162A | family with sequence similarity 162, member A | -0.0353347 |
| CCNL1 | cyclin L1 | -0.035121 |
| G0S2 | G0/G1 switch 2 | -0.0346066 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0343889 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0324988 |
| LDHA | lactate dehydrogenase A | -0.0319493 |
| S100A10 | S100 calcium binding protein A10 | -0.0317422 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.031596 |
| RNF145 | ring finger protein 145 | -0.0306983 |
| POTEF | POTE ankyrin domain family, member F | -0.0293603 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0293119 |
| PTMA | prothymosin, alpha | -0.0280356 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0266271 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0262271 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0256144 |
| RPS19 | ribosomal protein S19 | -0.0248159 |
| RPS23 | ribosomal protein S23 | -0.0246767 |
| RPLP0 | ribosomal protein, large, P0 | -0.0243218 |
| AREG | amphiregulin | -0.0241191 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0237668 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0232426 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | -0.0231578 |
| PCBP2 | poly(rC) binding protein 2 | -0.0225063 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0224592 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0210078 |
| RPL8 | ribosomal protein L8 | -0.0209596 |
| MAL2 | mal, T-cell differentiation protein 2 (gene/pseudogene) | -0.0208902 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0208571 |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain | -0.0206763 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | -0.02048 |
| RYBP | RING1 and YY1 binding protein | -0.0203923 |
| CLDN4 | claudin 4 | -0.0202902 |
| MXD1 | MAX dimerization protein 1 | -0.0197161 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | -0.0196181 |
| USP3 | ubiquitin specific peptidase 3 | -0.0194456 |
| TFG | TRK-fused gene | -0.0192667 |
| VDAC1 | voltage-dependent anion channel 1 | -0.018876 |
| QKI | QKI, KH domain containing, RNA binding | -0.0187403 |
| CD46 | CD46 molecule, complement regulatory protein | -0.018525 |
| RPLP1 | ribosomal protein, large, P1 | -0.0181556 |
| PFN1 | profilin 1 | -0.0180349 |
| MSMO1 | methylsterol monooxygenase 1 | -0.0180188 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0178508 |
| ZNF292 | zinc finger protein 292 | -0.0176402 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0176095 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0174214 |
| DEK | DEK proto-oncogene | -0.017164 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.017101 |
| RBM25 | RNA binding motif protein 25 | -0.0170973 |
| CHMP2B | charged multivesicular body protein 2B | -0.017086 |
| CCNI | cyclin I | -0.0170763 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0168943 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0168 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0167637 |
| TAPBP | TAP binding protein (tapasin) | -0.0167274 |
| TUBA1B | tubulin, alpha 1b | -0.016597 |
| SPINT2 | serine peptidase inhibitor, Kunitz type, 2 | -0.0165585 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.0162779 |
| RTN4 | reticulon 4 | -0.0162173 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0161504 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0161447 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.0160816 |
| NUP58 | nucleoporin 58 | -0.0160608 |
| DSTN | destrin (actin depolymerizing factor) | -0.0160092 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0159877 |
| PKM | pyruvate kinase, muscle | -0.0158833 |
| CD47 | CD47 molecule | -0.0156915 |
| RPS8 | ribosomal protein S8 | -0.0152795 |
| RPS4X | ribosomal protein S4, X-linked | -0.0151969 |
| TPI1 | triosephosphate isomerase 1 | -0.0151167 |
| PHLDA2 | pleckstrin homology-like domain, family A, member 2 | -0.0151103 |
| CD9 | CD9 molecule | -0.0150402 |
| S100A9 | S100 calcium binding protein A9 | -0.014981 |
| SEPTIN7 | septin 7 | -0.0149731 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0149196 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 | -0.0148952 |
| COX7C | cytochrome c oxidase subunit VIIc | -0.0147959 |
| RPL32 | ribosomal protein L32 | -0.014701 |
| FAM13A | family with sequence similarity 13, member A | -0.0144784 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0144337 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0144145 |
| RHOA | ras homolog family member A | -0.0142385 |
