| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | L-Thyroxine (sodium salt pentahydrate) perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the L-Thyroxine (sodium salt pentahydrate)_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COL11A1 | collagen, type XI, alpha 1 | 0.197967 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.134341 |
| PHIP | pleckstrin homology domain interacting protein | 0.0958956 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.0861709 |
| RPS6 | ribosomal protein S6 | 0.0774293 |
| NTM | neurotrimin | 0.0651109 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0648847 |
| CALR | calreticulin | 0.0638441 |
| PTMA | prothymosin, alpha | 0.056554 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | 0.0557527 |
| RPS8 | ribosomal protein S8 | 0.0548808 |
| RPS16 | ribosomal protein S16 | 0.0523916 |
| MDK | midkine (neurite growth-promoting factor 2) | 0.0516782 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.05111 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0497416 |
| RPL23 | ribosomal protein L23 | 0.0467293 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0442752 |
| PARD3B | par-3 family cell polarity regulator beta | 0.0436472 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0432417 |
| POTEF | POTE ankyrin domain family, member F | 0.0429298 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0412629 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0411368 |
| MED13L | mediator complex subunit 13-like | 0.04096 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0408252 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0398834 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0393318 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0389634 |
| PCDH9 | protocadherin 9 | 0.0385997 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0384447 |
| GOLIM4 | golgi integral membrane protein 4 | 0.0374544 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | 0.0373719 |
| B2M | beta-2-microglobulin | 0.0372077 |
| RPS12 | ribosomal protein S12 | 0.0371309 |
| RPS2 | ribosomal protein S2 | 0.036351 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0355171 |
| XPO1 | exportin 1 | 0.0352304 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0348651 |
| SFRP4 | secreted frizzled-related protein 4 | 0.0348599 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0348053 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0342756 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.0342493 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0339075 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 0.0338537 |
| RPL5 | ribosomal protein L5 | 0.0332234 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | 0.0331092 |
| FOXG1 | forkhead box G1 | 0.0328544 |
| SETD5 | SET domain containing 5 | 0.031886 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | 0.0314555 |
| RAD51B | RAD51 paralog B | 0.0314508 |
| PCBP2 | poly(rC) binding protein 2 | 0.0314434 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0308748 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | 0.0307132 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0305761 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.030496 |
| RPL19 | ribosomal protein L19 | 0.0299974 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0298763 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0291691 |
| LDHA | lactate dehydrogenase A | 0.0280246 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0279058 |
| UBE2K | ubiquitin-conjugating enzyme E2K | 0.0278742 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | 0.0276073 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | 0.0271947 |
| PGAP1 | post-GPI attachment to proteins 1 | 0.0271872 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0269148 |
| RPLP1 | ribosomal protein, large, P1 | 0.0268057 |
| PPIG | peptidylprolyl isomerase G (cyclophilin G) | 0.0268039 |
| RPS27 | ribosomal protein S27 | 0.0267129 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0265143 |
| MEF2A | myocyte enhancer factor 2A | 0.0264464 |
| SLC38A1 | solute carrier family 38, member 1 | 0.0261343 |
| RPL3 | ribosomal protein L3 | 0.0260377 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0257003 |
| STAG2 | stromal antigen 2 | 0.0256741 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0256575 |
| HMCN1 | hemicentin 1 | 0.0256006 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.0255922 |
| ENO1 | enolase 1, (alpha) | 0.0255855 |
| TLN1 | talin 1 | 0.0255803 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | 0.0252362 |
| NACA | nascent polypeptide-associated complex alpha subunit | 0.0250562 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0249626 |
| GALNTL6 | polypeptide N-acetylgalactosaminyltransferase-like 6 | 0.0249613 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0249459 |
| CBX3 | chromobox homolog 3 | 0.0249382 |
| SNX3 | sorting nexin 3 | 0.0249296 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0248846 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.024565 |
| SNX6 | sorting nexin 6 | 0.0245249 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0244746 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0244618 |
| RPS3 | ribosomal protein S3 | 0.0244596 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0244262 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0244145 |
| SFTPA2 | surfactant protein A2 | 0.0243915 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0242212 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0239256 |
| REST | RE1-silencing transcription factor | 0.0238641 |
| USP34 | ubiquitin specific peptidase 34 | 0.0238188 |
| PPP4R1 | protein phosphatase 4, regulatory subunit 1 | 0.0236809 |
| RPLP2 | ribosomal protein, large, P2 | 0.0236599 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FOXP2 | forkhead box P2 | -0.0829759 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | -0.0758187 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | -0.0670762 |
| GPC3 | glypican 3 | -0.0593801 |
| TENM3 | teneurin transmembrane protein 3 | -0.0591024 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0523204 |
| ZNF292 | zinc finger protein 292 | -0.0464465 |
| DST | dystonin | -0.0462636 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0458561 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0424361 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.042296 |
| CENPE | centromere protein E, 312kDa | -0.0422861 |
| FIGN | fidgetin | -0.0405166 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0402984 |
| COL5A2 | collagen, type V, alpha 2 | -0.0398034 |
| PDGFC | platelet derived growth factor C | -0.0383627 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0382014 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.0375632 |
| VAPA | VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa | -0.0373417 |
| SMYD3 | SET and MYND domain containing 3 | -0.0368859 |
| ZFPM2 | zinc finger protein, FOG family member 2 | -0.0361858 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0360335 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0355986 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0352444 |
| NCAM2 | neural cell adhesion molecule 2 | -0.0346439 |
| THBS1 | thrombospondin 1 | -0.0344571 |
| WDR43 | WD repeat domain 43 | -0.0329841 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0325956 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0313723 |
| YES1 | YES proto-oncogene 1, Src family tyrosine kinase | -0.0313629 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0313619 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.030904 |
| HMGA2 | high mobility group AT-hook 2 | -0.0303339 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0303251 |
| ECT2 | epithelial cell transforming 2 | -0.030217 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | -0.02924 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0286704 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | -0.0285586 |
| ANKRD50 | ankyrin repeat domain 50 | -0.0284663 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0281051 |
| PTK2 | protein tyrosine kinase 2 | -0.0280402 |
| DMD | dystrophin | -0.027148 |
| USP3 | ubiquitin specific peptidase 3 | -0.0267113 |
| PLEKHG1 | pleckstrin homology domain containing, family G (with RhoGef domain) member 1 | -0.0262536 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0257885 |
| AHNAK | AHNAK nucleoprotein | -0.0257122 |
| ZNF385D | zinc finger protein 385D | -0.0253315 |
| AK1 | adenylate kinase 1 | -0.0253091 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0248007 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | -0.0247443 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0247023 |
| PEG10 | paternally expressed 10 | -0.0246396 |
| CDC50A | cell division cycle 50 P4-ATPase accessory subunit A | -0.0236339 |
| SH3RF2 | SH3 domain containing ring finger 2 | -0.0236315 |
| MAN1A2 | mannosidase, alpha, class 1A, member 2 | -0.0235819 |
| H1-0 | H1.0 linker histone | -0.0235775 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.023567 |
| TXNRD1 | thioredoxin reductase 1 | -0.0233424 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.023092 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0230726 |
| EP300 | E1A binding protein p300 | -0.0229052 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0228823 |
| RAB2A | RAB2A, member RAS oncogene family | -0.0226097 |
| ANKRD33B | ankyrin repeat domain 33B | -0.0225941 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | -0.0225614 |
| SIK3 | SIK family kinase 3 | -0.0223265 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | -0.0221237 |
| USP25 | ubiquitin specific peptidase 25 | -0.0220905 |
| WASHC4 | WASH complex subunit 4 | -0.0218548 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0217834 |
| SLC16A1 | solute carrier family 16 (monocarboxylate transporter), member 1 | -0.0217329 |
| PRELID2 | PRELI domain containing 2 | -0.0216964 |
| FUBP1 | far upstream element (FUSE) binding protein 1 | -0.0216047 |
| METAP2 | methionyl aminopeptidase 2 | -0.0214196 |
| VCL | vinculin | -0.0213587 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0212932 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.021176 |
| NEK7 | NIMA-related kinase 7 | -0.0207315 |
| FOXJ3 | forkhead box J3 | -0.0206748 |
| NUP98 | nucleoporin 98kDa | -0.0204806 |
| XPO5 | exportin 5 | -0.0203714 |
| CAMKMT | calmodulin-lysine N-methyltransferase | -0.0203019 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0202135 |
| ZEB2 | zinc finger E-box binding homeobox 2 | -0.0202069 |
| ACTN4 | actinin, alpha 4 | -0.0201349 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0201144 |
| CUL3 | cullin 3 | -0.0199854 |
| ACTG1 | actin gamma 1 | -0.0199681 |
| HS3ST5 | heparan sulfate (glucosamine) 3-O-sulfotransferase 5 | -0.0199506 |
| PHF3 | PHD finger protein 3 | -0.0198409 |
| SYT1 | synaptotagmin I | -0.0196047 |
| CXADR | coxsackie virus and adenovirus receptor | -0.019397 |
| WDR70 | WD repeat domain 70 | -0.019382 |
| PROS1 | protein S (alpha) | -0.0193267 |
| G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | -0.0191153 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -0.019043 |
| NUSAP1 | nucleolar and spindle associated protein 1 | -0.0189861 |
| HDAC8 | histone deacetylase 8 | -0.0189802 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0189203 |
| WASHC5 | WASH complex subunit 5 | -0.0188629 |
